LOCUS       NM_020280                948 bp    mRNA    linear   ROD 23-NOV-2023
DEFINITION  Mus musculus MAGE family member A4 (Magea4), mRNA.
ACCESSION   NM_020280
VERSION     NM_020280.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Fon Tacer K, Montoya MC, Oatley MJ, Lord T, Oatley JM, Klein J,
            Ravichandran R, Tillman H, Kim M, Connelly JP, Pruett-Miller SM,
            Bookout AL, Binshtock E, Kaminski MM and Potts PR.
  TITLE     MAGE cancer-testis antigens protect the mammalian germline under
            environmental stress
  JOURNAL   Sci Adv 5 (5), eaav4832 (2019)
   PUBMED   31149633
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  AUTHORS   Gordeeva O, Gordeev A and Khaydukov S.
  TITLE     Expression dynamics of Mage family genes during self-renewal and
            differentiation of mouse pluripotent stem and teratocarcinoma cells
  JOURNAL   Oncotarget 10 (35), 3248-3266 (2019)
   PUBMED   31143371
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 948)
  AUTHORS   Sakurai T, Itoh K, Higashitsuji H, Nagao T, Nonoguchi K, Chiba T
            and Fujita J.
  TITLE     A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in
            human cells
  JOURNAL   J Biol Chem 279 (15), 15505-15514 (2004)
   PUBMED   14739298
  REMARK    GeneRIF: a cleaved form of MAGE-A4 binds to Miz-1 and induces
            apoptosis
REFERENCE   4  (bases 1 to 948)
  AUTHORS   Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T and Lucas S.
  TITLE     An overview of the MAGE gene family with the identification of all
            human members of the family
  JOURNAL   Cancer Res 61 (14), 5544-5551 (2001)
   PUBMED   11454705
REFERENCE   5  (bases 1 to 948)
  AUTHORS   De Plaen E, De Backer O, Arnaud D, Bonjean B, Chomez P, Martelange
            V, Avner P, Baldacci P, Babinet C, Hwang SY, Knowles B and Boon T.
  TITLE     A new family of mouse genes homologous to the human MAGE genes
  JOURNAL   Genomics 55 (2), 176-184 (1999)
   PUBMED   9933564
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671874.17.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by NM_020280.3.
            
            On Aug 12, 2009 this sequence version replaced NM_020280.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC104089.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-948               AL671874.17        174328-175275
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.2 cM"
     gene            1..948
                     /gene="Magea4"
                     /gene_synonym="Mage-a4"
                     /note="MAGE family member A4"
                     /db_xref="GeneID:17140"
                     /db_xref="MGI:MGI:1333839"
     CDS             1..948
                     /gene="Magea4"
                     /gene_synonym="Mage-a4"
                     /note="melanoma antigen, family A, 4"
                     /codon_start=1
                     /product="melanoma-associated antigen 4"
                     /protein_id="NP_064676.2"
                     /db_xref="CCDS:CCDS30185.1"
                     /db_xref="GeneID:17140"
                     /db_xref="MGI:MGI:1333839"
                     /translation="MENPDNTHYCSLQGSARSQRELDNVQATIAVVDEEEATPTSKKV
                     YSSGIPSPPQSPQRASSPLVILASVPEGPSEEASTNQVEEQEDPLCMLYNAQNIKLYE
                     LATFLFFKYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECFKLVSGIGMIEVDPFV
                     QSYILVPALGLTYDGMLTDVQSKPKTGILIVVLGAIFTQGNCVSEEIIWKMLNNIGLY
                     GGRHLYIHQDPRKFISEEFVQEGYLEYRQVPNSDPPSYEFLWDPRAFAETTKMKVLEI
                     FASITMTDPRAYTEKYAEALRDETERAQARIIQQIVLQL"
     exon            1..948
                     /gene="Magea4"
                     /gene_synonym="Mage-a4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggaaaatc ccgataacac ccattactgc agcctccaag gcagtgctcg gagccaaagg
       61 gagttagaca atgttcaggc tacaatagct gtggtagatg aagaggaagc cactcccacc
      121 tcaaagaagg tgtacagtag tggaatacca agtcctcccc agagtcctca aagagcctcc
      181 tctccccttg tgatactagc ctctgttcct gaaggcccat ctgaggaagc ttccaccaac
      241 caagtagagg aacaggaaga cccactgtgc atgttgtaca atgcacagaa cataaagtta
      301 tatgaattgg caacctttct gtttttcaaa tatcaaatga aggcatttac taccaaagca
      361 gaaatgctgg aaagtattgg tagagagtat gaggagtact accctctgat ctttagtgag
      421 gcctctgagt gctttaagct ggtctctggc attggcatga tagaagtgga cccatttgtc
      481 caatcctata tccttgtccc tgccctgggg ctcacctatg atgggatgct gactgatgtt
      541 cagagtaagc ccaagacagg tatcctaata gttgttcttg gtgctatttt cacgcaagga
      601 aactgtgtca gtgaggagat tatctggaaa atgctgaata acatagggtt gtatggtggg
      661 aggcatcttt acatacatca agaccccagg aagttcatct ctgaggagtt tgtgcaggaa
      721 gggtacctgg aatacaggca ggtgcctaat agtgatcctc caagctatga gtttctgtgg
      781 gacccaaggg cctttgcaga aaccaccaaa atgaaagtct tggagatttt tgccagcatt
      841 actatgaccg atcccagagc ttacactgaa aaatacgcag aggctttgag agatgagaca
      901 gagagggccc aggccaggat catccagcag atagttctac agctctga
//
