LOCUS       NM_020016               1685 bp    mRNA    linear   ROD 23-NOV-2023
DEFINITION  Mus musculus MAGE family member A2 (Magea2), mRNA.
ACCESSION   NM_020016
VERSION     NM_020016.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Fon Tacer K, Montoya MC, Oatley MJ, Lord T, Oatley JM, Klein J,
            Ravichandran R, Tillman H, Kim M, Connelly JP, Pruett-Miller SM,
            Bookout AL, Binshtock E, Kaminski MM and Potts PR.
  TITLE     MAGE cancer-testis antigens protect the mammalian germline under
            environmental stress
  JOURNAL   Sci Adv 5 (5), eaav4832 (2019)
   PUBMED   31149633
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  AUTHORS   Gordeeva O, Gordeev A and Khaydukov S.
  TITLE     Expression dynamics of Mage family genes during self-renewal and
            differentiation of mouse pluripotent stem and teratocarcinoma cells
  JOURNAL   Oncotarget 10 (35), 3248-3266 (2019)
   PUBMED   31143371
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1685)
  AUTHORS   Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T and Lucas S.
  TITLE     An overview of the MAGE gene family with the identification of all
            human members of the family
  JOURNAL   Cancer Res 61 (14), 5544-5551 (2001)
   PUBMED   11454705
REFERENCE   4  (bases 1 to 1685)
  AUTHORS   Van Pel A, De Plaen E, Duffour MT, Warnier G, Uyttenhove C,
            Perricaudet M and Boon T.
  TITLE     Induction of cytolytic T lymphocytes by immunization of mice with
            an adenovirus containing a mouse homolog of the human MAGE-A genes
  JOURNAL   Cancer Immunol Immunother 49 (11), 593-602 (2001)
   PUBMED   11225990
REFERENCE   5  (bases 1 to 1685)
  AUTHORS   De Plaen E, De Backer O, Arnaud D, Bonjean B, Chomez P, Martelange
            V, Avner P, Baldacci P, Babinet C, Hwang SY, Knowles B and Boon T.
  TITLE     A new family of mouse genes homologous to the human MAGE genes
  JOURNAL   Genomics 55 (2), 176-184 (1999)
   PUBMED   9933564
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ005526.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC106842.2, AA562292.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN00849384, SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="129"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 72.38 cM"
     gene            1..1685
                     /gene="Magea2"
                     /gene_synonym="Mage-a2"
                     /note="MAGE family member A2"
                     /db_xref="GeneID:17138"
                     /db_xref="MGI:MGI:1333793"
     exon            1..40
                     /gene="Magea2"
                     /gene_synonym="Mage-a2"
                     /inference="alignment:Splign:2.1.0"
     exon            41..145
                     /gene="Magea2"
                     /gene_synonym="Mage-a2"
                     /inference="alignment:Splign:2.1.0"
     exon            146..234
                     /gene="Magea2"
                     /gene_synonym="Mage-a2"
                     /inference="alignment:Splign:2.1.0"
     exon            235..1685
                     /gene="Magea2"
                     /gene_synonym="Mage-a2"
                     /inference="alignment:Splign:2.1.0"
     CDS             300..1262
                     /gene="Magea2"
                     /gene_synonym="Mage-a2"
                     /note="melanoma antigen, family A, 2"
                     /codon_start=1
                     /product="melanoma antigen family A, 2"
                     /protein_id="NP_064400.1"
                     /db_xref="CCDS:CCDS30491.1"
                     /db_xref="GeneID:17138"
                     /db_xref="MGI:MGI:1333793"
                     /translation="MADSHNTQYCSLQESAQAQQELDNDQETMETSEEEEDTTTSNKV
                     YGSGIPSPPQSPQRAYSPCVALASIPDSPSEEASIKGSGGLEDPLYLLHNAQNTKVYD
                     LVDFLVLNYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEVDPSV
                     HSYILVTALGITYDGMMTDVLGMPKTGILIAVLSVIFMKGNYVSEEIIWEMVNNIGLC
                     GGRDPYIHKDPRKLISEEFVQEGCLKYRQVPNSDPPSYGFLWGPRAFAETSKMKVLQF
                     FASINKTHPRAYPEKYAEALQDEIDRTKAWILNRCSNSSDLLTF"
ORIGIN      
        1 agcgtcctgg aagggaggtc tccatgctgt gccagttgag agagcacctc gccagccaat
       61 cgtatctgga gactttgtgg acttgaacta ggcgccattt tgggagaagc ctgagatggg
      121 agatcgctct gcagtgccag tttaggtccc tggtatcaag gagctgaaaa tctcctaaag
      181 cagagtttga ctagagtcat cagagggaag atctcaggag tgtcaggact gaaggcccgt
      241 gtttcctccc tgctgtgatt ggaacactat ccagcctact gttacctagg acagtcataa
      301 tggctgactc ccataacacc caatactgca gcctccaaga gagtgctcag gcccaacagg
      361 aattagacaa tgaccaggag accatggaga catcagagga ggaggaagat accaccacct
      421 caaataaagt gtatggcagt ggaataccaa gtcctcccca gagtcctcag agagcctact
      481 ctccctgtgt ggcactggcc tccatccctg atagcccatc tgaggaagct tccatcaaag
      541 gatcaggggg cctggaagac ccactttatt tgttgcacaa tgcacagaac acaaaggtgt
      601 atgacttggt ggactttctg gttttaaact atcaaatgaa ggcattcact accaaagcag
      661 aaatgttgga aagtattggt agagagtatg aggagtacta ccctctgatc tttagtgagg
      721 cctctgagtg cttgaagatg gtctttggcc ttgacatggt agaagtggac ccctctgtcc
      781 actcctatat ccttgtcact gccctgggga tcacctatga tggcatgatg actgatgtcc
      841 tgggtatgcc caagacaggt atcctcatag ctgtactgag tgtcattttc atgaagggaa
      901 actatgtcag tgaggagatt atctgggaaa tggtgaataa cataggattg tgtggtggga
      961 gggatcctta catacataaa gaccccagga agctcatctc tgaggagttt gtgcaggaag
     1021 ggtgcctgaa atacaggcag gtgcccaata gtgatcctcc tagctatggg ttcctgtggg
     1081 gcccaagggc ttttgcagaa accagcaaaa tgaaagtctt acagtttttt gccagcatta
     1141 ataagactca tcccagagcc taccctgaaa agtatgcaga ggctttgcaa gatgagatag
     1201 acaggaccaa ggcctggatc ttgaacagat gctccaactc ctctgacctg ctcacattct
     1261 agtgtagtgg catttccctt ctaaccccag gtcagacaga gtcactgatt ccattgctgt
     1321 accctcattg gacagctggg tggaggagag cataacacat tcaattttca ctctgtttgg
     1381 gtgacttgag gattcttggt agcccaaaat gttaataatc gtagtataag gtccaatagt
     1441 tttagcttta aatgcatgta gtgttttttt caggtttgct gaatgtcatt ttttttaaat
     1501 aaatgggaat gacttgtgta ttaatttgta aaatgtttca agatactagc gacattgaaa
     1561 ctaattttct gggcaatgga aaaatgtgaa tatttaaaaa aaagaagaag aaaagatttt
     1621 tcatcatctc aaactgttta gtctcttgtt gtgtttaaca aattaaaatt caaactgaaa
     1681 acagt
//
