LOCUS       NM_020015               1272 bp    mRNA    linear   ROD 23-NOV-2023
DEFINITION  Mus musculus MAGE family member A1 (Magea1), mRNA.
ACCESSION   NM_020015 XM_001006950
VERSION     NM_020015.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1272)
  AUTHORS   Fon Tacer K, Montoya MC, Oatley MJ, Lord T, Oatley JM, Klein J,
            Ravichandran R, Tillman H, Kim M, Connelly JP, Pruett-Miller SM,
            Bookout AL, Binshtock E, Kaminski MM and Potts PR.
  TITLE     MAGE cancer-testis antigens protect the mammalian germline under
            environmental stress
  JOURNAL   Sci Adv 5 (5), eaav4832 (2019)
   PUBMED   31149633
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1272)
  AUTHORS   Gao X, Nan Y, Yuan Y, Gong X, Sun Y, Zhou H, Zong Y, Zhang L and Yu
            M.
  TITLE     Gas-filled ultrasound microbubbles enhance the immunoactivity of
            the HSP70-MAGEA1 fusion protein against MAGEA1-expressing tumours
  JOURNAL   Mol Med Rep 18 (1), 315-321 (2018)
   PUBMED   29749485
  REMARK    GeneRIF: HSP70MAGEA1 delivered via microbubbles clearly inhibited
            and delayed the growth of MAGEA1expressing B16 melanomas in mice
            and improved the survival times of these animals compared with the
            fusion protein alone.
REFERENCE   3  (bases 1 to 1272)
  AUTHORS   Jiang J, Xie D, Zhang W, Xiao G and Wen J.
  TITLE     Fusion of Hsp70 to Mage-a1 enhances the potency of vaccine-specific
            immune responses
  JOURNAL   J Transl Med 11, 300 (2013)
   PUBMED   24314011
  REMARK    GeneRIF: results indicate that the fusion of Hsp70 to Mage-a1 can
            enhance immune responses and anti-tumor effects against
            Mage-a1-expressing tumors
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1272)
  AUTHORS   Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T and Lucas S.
  TITLE     An overview of the MAGE gene family with the identification of all
            human members of the family
  JOURNAL   Cancer Res 61 (14), 5544-5551 (2001)
   PUBMED   11454705
REFERENCE   5  (bases 1 to 1272)
  AUTHORS   De Plaen E, De Backer O, Arnaud D, Bonjean B, Chomez P, Martelange
            V, Avner P, Baldacci P, Babinet C, Hwang SY, Knowles B and Boon T.
  TITLE     A new family of mouse genes homologous to the human MAGE genes
  JOURNAL   Genomics 55 (2), 176-184 (1999)
   PUBMED   9933564
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC116904.1 and CJ223782.1.
            
            On Oct 31, 2007 this sequence version replaced NM_020015.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1105              BC116904.1         1-1105
            1106-1272           CJ223782.1         221-387
FEATURES             Location/Qualifiers
     source          1..1272
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 72.38 cM"
     gene            1..1272
                     /gene="Magea1"
                     /gene_synonym="Mage-a1"
                     /note="MAGE family member A1"
                     /db_xref="GeneID:17137"
                     /db_xref="MGI:MGI:1333834"
     exon            1..1272
                     /gene="Magea1"
                     /gene_synonym="Mage-a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..1025
                     /gene="Magea1"
                     /gene_synonym="Mage-a1"
                     /note="melanoma antigen, family A, 1"
                     /codon_start=1
                     /product="melanoma antigen family A, 1"
                     /protein_id="NP_064399.1"
                     /db_xref="CCDS:CCDS30493.1"
                     /db_xref="GeneID:17137"
                     /db_xref="MGI:MGI:1333834"
                     /translation="MADSRNTQYCSLQESAQAQQELDNDQETMETSEEEEDTTTSNKV
                     YGSGIPSPPQSPQRAYSPCVALASIPDSPSEEASIKGSGGLEDPLYLLHNAQNTKVYD
                     LVDFLVLNYQMKAFTTKAEMLESIGREYEEYYPLIFSEASECLKMVFGLDMVEVDPSV
                     HSYILVTALGITYDGMMTDVQGMPKTGILIAVLSVIFMKGNYVSEEIIWEMVNNIGLC
                     GGRDPYIHKDPRKLISEEFVQEGCLKYRQVPNSDPPSYGFLWGPRAFAETSKMKVLQF
                     FASINKTHPRAYPEKYAEALRDEIYRTKAWILNRCSNFSDLLTF"
ORIGIN      
        1 cgtgtttcct ccctgctgtg attggaacac tatccagcct actgttacct aggacagtca
       61 taatggctga ctcccgtaac acccaatact gcagcctcca agagagtgct caggcccaac
      121 aggaattaga caatgaccag gaaaccatgg agacgtcaga ggaggaggaa gataccacca
      181 cctcaaataa agtgtatggc agtggaatac caagtcctcc ccagagtcct cagagagcct
      241 actctccctg tgtggcactg gcctccatcc ctgatagccc atctgaggaa gcttccatca
      301 aaggatcagg gggcctggaa gacccacttt atttgttgca caatgcacag aacacaaagg
      361 tgtatgactt ggtggacttt ctggttttaa actatcaaat gaaggcattc actaccaaag
      421 cagaaatgtt ggaaagtatt ggtagagagt atgaggagta ctaccctctg atctttagtg
      481 aggcctctga gtgcttgaag atggtctttg gccttgacat ggtagaagtg gacccctctg
      541 tccactccta tatccttgtc actgccctgg ggatcaccta tgatggcatg atgactgatg
      601 tccagggtat gcccaagaca ggtatcctca tagctgtact gagtgtcatt ttcatgaagg
      661 gaaactatgt cagtgaggag attatctggg aaatggtgaa taacatagga ttgtgtggtg
      721 ggagggatcc ttacatacat aaagacccca ggaagctcat ctctgaggag tttgtgcagg
      781 aagggtgcct gaaatacagg caggtgccca atagtgatcc tcctagctat gggttcctgt
      841 ggggcccaag ggcttttgca gaaaccagca aaatgaaagt cttacagttt tttgccagca
      901 ttaataagac tcatcccaga gcctaccctg aaaagtatgc agaggctttg cgagatgaga
      961 tatacaggac caaggcctgg atcttgaaca gatgctccaa cttctctgac ctgctcacat
     1021 tctagtgtat tggcatttcc cttctaaccc caggtcagac agagtcactg attccattgt
     1081 tgtaccctca ttggacagct gggtggagga gagcataaca cattcaattt tcactctgtt
     1141 tgggtgactt gaggattctt ggtagcccaa aatgttaata atcgtagtat aaggtccaat
     1201 agttttagct ttaaatgcat gtagtgtttt tttcaggttt gctgaatgtc atttttttta
     1261 aataaatggg aa
//
