LOCUS       NM_010757               2825 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus v-maf musculoaponeurotic fibrosarcoma oncogene family,
            protein K (avian) (Mafk), mRNA.
ACCESSION   NM_010757
VERSION     NM_010757.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2825)
  AUTHORS   Patel,S.D., Anand,D., Motohashi,H., Katsuoka,F., Yamamoto,M. and
            Lachke,S.A.
  TITLE     Deficiency of the bZIP transcription factors Mafg and Mafk causes
            misexpression of genes in distinct pathways and results in lens
            embryonic developmental defects
  JOURNAL   Front Cell Dev Biol 10, 981893 (2022)
   PUBMED   36092713
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2825)
  AUTHORS   Abdellatif,A.M., Oishi,H., Itagaki,T., Jung,Y., Shawki,H.H.,
            Okita,Y., Hasegawa,Y., Suzuki,H., El-Morsy,S.E., El-Sayed,M.A.,
            Shoaib,M.B., Sugiyama,F. and Takahashi,S.
  TITLE     beta-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine
            Cell Development
  JOURNAL   PLoS One 11 (2), e0150010 (2016)
   PUBMED   26901059
  REMARK    GeneRIF: beta-Cell-Specific Mafk Overexpression Impairs Pancreatic
            Endocrine Cell Development
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2825)
  AUTHORS   Agrawal,S.A., Anand,D., Siddam,A.D., Kakrana,A., Dash,S.,
            Scheiblin,D.A., Dang,C.A., Terrell,A.M., Waters,S.M., Singh,A.,
            Motohashi,H., Yamamoto,M. and Lachke,S.A.
  TITLE     Compound mouse mutants of bZIP transcription factors Mafg and Mafk
            reveal a regulatory network of non-crystallin genes associated with
            cataract
  JOURNAL   Hum Genet 134 (7), 717-735 (2015)
   PUBMED   25896808
  REMARK    GeneRIF: These data identify Mafg and Mafk as new
            cataract-associated candidates and define their function in
            regulating largely non-crystallin genes linked to human cataract.
REFERENCE   4  (bases 1 to 2825)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 2825)
  AUTHORS   Hwang,Y.J., Lee,E.W., Song,J., Kim,H.R., Jun,Y.C. and Hwang,K.A.
  TITLE     MafK positively regulates NF-kappaB activity by enhancing
            CBP-mediated p65 acetylation
  JOURNAL   Sci Rep 3, 3242 (2013)
   PUBMED   24247732
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2825)
  AUTHORS   Igarashi,K., Itoh,K., Motohashi,H., Hayashi,N., Matuzaki,Y.,
            Nakauchi,H., Nishizawa,M. and Yamamoto,M.
  TITLE     Activity and expression of murine small Maf family protein MafK
  JOURNAL   J Biol Chem 270 (13), 7615-7624 (1995)
   PUBMED   7706310
REFERENCE   7  (bases 1 to 2825)
  AUTHORS   Noguchi,M., Kitabatake,A., Ishibashi,T. and Kasahara,M.
  TITLE     The MHC class I-like Zn-alpha 2-glycoprotein gene maps to mouse
            chromosome 5
  JOURNAL   Immunogenetics 42 (1), 72-74 (1995)
   PUBMED   7797272
REFERENCE   8  (bases 1 to 2825)
  AUTHORS   Peters,L.L. and Eicher,E.M.
  TITLE     The ubiquitous subunit of the globin enhancer-binding protein NF-E2
            (Nfe2u) maps to mouse chromosome 5
  JOURNAL   Genomics 22 (2), 490-491 (1994)
   PUBMED   7806243
REFERENCE   9  (bases 1 to 2825)
  AUTHORS   Igarashi,K., Kataoka,K., Itoh,K., Hayashi,N., Nishizawa,M. and
            Yamamoto,M.
  TITLE     Regulation of transcription by dimerization of erythroid factor
            NF-E2 p45 with small Maf proteins
  JOURNAL   Nature 367 (6463), 568-572 (1994)
   PUBMED   8107826
REFERENCE   10 (bases 1 to 2825)
  AUTHORS   Andrews,N.C., Kotkow,K.J., Ney,P.A., Erdjument-Bromage,H.,
            Tempst,P. and Orkin,S.H.
  TITLE     The ubiquitous subunit of erythroid transcription factor NF-E2 is a
            small basic-leucine zipper protein related to the v-maf oncogene
  JOURNAL   Proc Natl Acad Sci U S A 90 (24), 11488-11492 (1993)
   PUBMED   8265578
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC167333.3.
            
            On Nov 17, 2006 this sequence version replaced NM_010757.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D42124.1, BC014295.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               AC167333.3         53117-53293         c
            178-257             AC167333.3         45611-45690         c
            258-2825            AC167333.3         42177-44744         c
FEATURES             Location/Qualifiers
     source          1..2825
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 78.81 cM"
     gene            1..2825
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /note="v-maf musculoaponeurotic fibrosarcoma oncogene
                     family, protein K (avian)"
                     /db_xref="GeneID:17135"
                     /db_xref="MGI:MGI:99951"
     exon            1..177
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /inference="alignment:Splign:2.1.0"
     exon            178..257
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..692
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /note="erythroid transcription factor NF-E2 p18 subunit;
                     nuclear factor, erythroid derived 2, ubiquitous; p18
                     NF-E2"
                     /codon_start=1
                     /product="transcription factor MafK"
                     /protein_id="NP_034887.1"
                     /db_xref="CCDS:CCDS19814.1"
                     /db_xref="GeneID:17135"
                     /db_xref="MGI:MGI:99951"
                     /translation="MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGL
                     TKEEVTRLKQRRRTLKNRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRL
                     ELDALRSKYEALQTFARTVARGPVTPTKVATTSVITIVKSAELSSTSVPFSAAS"
     exon            258..2825
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2801..2806
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /note="hexamer: AATAAA"
     polyA_site      2823
                     /gene="Mafk"
                     /gene_synonym="NF-E2; Nfe2u"
                     /note="major polyA site"
ORIGIN      
        1 tggggagccg gcggcgggcg gcgggtggca gggacttgtt gttcttcgcc gagtcggaac
       61 gagaagtccg aagcgcgcag gcggagacgg cgactaaggg gagcgcgaga gcagaagcgc
      121 ttgtgaagag tgcgtgtccg caaggagccg ccgcgcccgg ccccgcgcgc gacccggcta
      181 cgattttctg gtggttccgt cctggtgaca gggcccgggt tatgacgact aatcccaagc
      241 ccaacaaggc attgaaggtc aagaaggagg cgggtgagaa cgcccctgtt cttagcgatg
      301 atgagctggt gtccatgtca gtgcgggagc taaaccagca cctgcggggg ctcaccaagg
      361 aggaggtcac tcggctgaag cagcggcggc gcacactcaa gaacagaggc tacgcggcta
      421 gctgtcgcat caagcgtgtg acacagaaag aggagctgga acggcagcgt gtggagctac
      481 agcaggaggt ggagaagctg gctcgagaga acagcagcat gcggctggag ctagatgccc
      541 tgcgctccaa gtatgaggcc ctacagacct tcgctcgcac cgtggcccga gggcctgtca
      601 cacccaccaa ggtggccacc accagtgtca tcaccatcgt caaatctgcc gagctctcct
      661 ccacctctgt acccttctca gccgcctcct agtgtctgct ggggccgggc agggtgcggg
      721 cagtggcaca gccctcatgc ctatcccagg ctccctggca cagattcctc atgtctacct
      781 gcccactgtg aaccctgcgg ggctgagggc agggacagca ggaacagcag ggacagcaga
      841 tgcaggataa aagggaagct ctcaggagcc agtgcctcaa gcaacgccct ctcaaatctc
      901 tccttcccct gggggtgtgt ttttaggagc tggcaggaac cacatggcca accaggatga
      961 acaactctag gcccctgcag cagagtgtga ggactcggtc ttccacttct ccggtgcctg
     1021 cttgtcagca ccgttggtgc cgtcccctct aagggcctcc agctggggta gacaccattc
     1081 tgcctgtccc tttctgggct tgggccttct tgtccttatc aaagggcgct acaacctgct
     1141 ttagctctta gagccaggct catgtcctgg gaaacacttg caggggctaa tgtctgtgtt
     1201 cctgtgtgta cacaggctac catcacagcc tgtggagact ggaaaccgat ggccaggtgg
     1261 ccacatggga gagcctgtcc agtatgtgcg ccgagggttg catgaatgtc atggagtgtc
     1321 cctggaggtc tggtagactg cccattgtgg tgctgcaggg gccgcctgtc cacagagcca
     1381 gcaaacagcc aggctggggt tctctggggc ttagcagagg ggagagagag agaggagcag
     1441 gtgaagcctg agaggtgctg agagatgtcg ctggcaggtg agacgtgtgt tgctgcaaaa
     1501 agaacaggaa cgaagtagac agggatagtg cggagtcctg gcagtcgagg tccaggggat
     1561 gtggaagagg cctgagaggc atagtattaa gggacagaga ctgagtccgg agggccttgt
     1621 ggacacaccc atggtaggca ggtcagcaag gaccccaggc agactgtaag ttgcaaatac
     1681 tctgcatctt tggtgcccac ttgttaccta agccttttcc tccttcatag agctctgggg
     1741 ccactggaca tcttgcgctt ttttactgaa ggaatcgtgt cctccaggtc ctggggaata
     1801 tggtagacag ggagtcaggg gcaggctgag tcacagccag gcacttagaa agcaagcact
     1861 gttggaacca tagccttggt aggtaatcca tattggatat caataaggac catggatatt
     1921 taaagagaga agatattata tatatataat tatacacaca ttttatcgta cagatttttc
     1981 ataacaattt tctttcccag tttgatactg tagatcttta ttaatgcaga gtaggttgga
     2041 cggtggggtg gggaacgaag gcccagggtg ccaacagcct tcctcagtct ttcctgcggt
     2101 ggcactgggc agctgggtca ctggtgaagc ctgctccagc acgtgtcacg ctggatgagt
     2161 acagtggtag gcagatgacc actgactgtc atcttttctg tggtggcact gggcatgctg
     2221 ggccactggt gaagcctgct ccagcacgtg tcacactgga tgagtacagt ggtaggcaga
     2281 tgaccactga ctgtggcttg ctgcccacgc ctggcctgtg gtggtcttcc tgggcggagg
     2341 ctccatattc ttggcctcca gggtagacag ggctgtcagt gctacccgga gcacccgtgc
     2401 agggcacctg cctggagggg ctgggaaggg tgtgagtgcg ccccatggca ctgtgtcact
     2461 gaaatttcat tgtcacaatt taatatatgg acatttttat ttaaagataa aagtgagttt
     2521 tctgtcttgt tcctttgact tctgaaagta agctttaact ttttcaaaag gtgacaggga
     2581 cacatgctga ccacgcagag acctggcatc ctcagccacc tgccacttgg caatttcatt
     2641 tcaatattta tttttttgtg cttttttttc cctaccatgt tataaattat tgagaaaaga
     2701 tcaagatcac agactgttgg ccccctgtct gccccctgcc tcatggccac cacctaattt
     2761 attgctgtac atgttgccgt gactgctttt gtatctttgc aataaagaat ttcctgtttg
     2821 ggatg
//
