LOCUS       NM_001304832            2022 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus v-maf musculoaponeurotic fibrosarcoma oncogene family,
            protein F (avian) (Maff), transcript variant 4, mRNA.
ACCESSION   NM_001304832 XM_006520548
VERSION     NM_001304832.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Deng,M., Tan,X., Peng,X., Zheng,W., Fu,R. and Tao,S.
  TITLE     HDAC6 promotes inflammation in lupus nephritis mice by regulating
            transcription factors MAFF and KLF5 in renal fibrosis
  JOURNAL   Ren Fail 46 (2), 2415517 (2024)
   PUBMED   39412062
  REMARK    GeneRIF: HDAC6 promotes inflammation in lupus nephritis mice by
            regulating transcription factors MAFF and KLF5 in renal fibrosis.
REFERENCE   2  (bases 1 to 2022)
  AUTHORS   von Scheidt,M., Zhao,Y., de Aguiar Vallim,T.Q., Che,N., Wierer,M.,
            Seldin,M.M., Franzen,O., Kurt,Z., Pang,S., Bongiovanni,D.,
            Yamamoto,M., Edwards,P.A., Ruusalepp,A., Kovacic,J.C., Mann,M.,
            Bjorkegren,J.L.M., Lusis,A.J., Yang,X. and Schunkert,H.
  TITLE     Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription
            Factor F) Regulates an Atherosclerosis Relevant Network Connecting
            Inflammation and Cholesterol Metabolism
  JOURNAL   Circulation 143 (18), 1809-1823 (2021)
   PUBMED   33626882
  REMARK    GeneRIF: Transcription Factor MAFF (MAF Basic Leucine Zipper
            Transcription Factor F) Regulates an Atherosclerosis Relevant
            Network Connecting Inflammation and Cholesterol Metabolism.
REFERENCE   3  (bases 1 to 2022)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   4  (bases 1 to 2022)
  AUTHORS   Agrawal,S.A., Anand,D., Siddam,A.D., Kakrana,A., Dash,S.,
            Scheiblin,D.A., Dang,C.A., Terrell,A.M., Waters,S.M., Singh,A.,
            Motohashi,H., Yamamoto,M. and Lachke,S.A.
  TITLE     Compound mouse mutants of bZIP transcription factors Mafg and Mafk
            reveal a regulatory network of non-crystallin genes associated with
            cataract
  JOURNAL   Hum Genet 134 (7), 717-735 (2015)
   PUBMED   25896808
REFERENCE   5  (bases 1 to 2022)
  AUTHORS   Osipovich,A.B., Long,Q., Manduchi,E., Gangula,R., Hipkens,S.B.,
            Schneider,J., Okubo,T., Stoeckert,C.J. Jr., Takada,S. and
            Magnuson,M.A.
  TITLE     Insm1 promotes endocrine cell differentiation by modulating the
            expression of a network of genes that includes Neurog3 and Ripply3
  JOURNAL   Development 141 (15), 2939-2949 (2014)
   PUBMED   25053427
REFERENCE   6  (bases 1 to 2022)
  AUTHORS   Murphy,P. and Kolsto,A.
  TITLE     Expression of the bZIP transcription factor TCF11 and its potential
            dimerization partners during development
  JOURNAL   Mech Dev 97 (1-2), 141-148 (2000)
   PUBMED   11025215
REFERENCE   7  (bases 1 to 2022)
  AUTHORS   Onodera,K., Shavit,J.A., Motohashi,H., Katsuoka,F., Akasaka,J.E.,
            Engel,J.D. and Yamamoto,M.
  TITLE     Characterization of the murine mafF gene
  JOURNAL   J Biol Chem 274 (30), 21162-21169 (1999)
   PUBMED   10409670
REFERENCE   8  (bases 1 to 2022)
  AUTHORS   Martin,F., van Deursen,J.M., Shivdasani,R.A., Jackson,C.W.,
            Troutman,A.G. and Ney,P.A.
  TITLE     Erythroid maturation and globin gene expression in mice with
            combined deficiency of NF-E2 and nrf-2
  JOURNAL   Blood 91 (9), 3459-3466 (1998)
   PUBMED   9558405
REFERENCE   9  (bases 1 to 2022)
  AUTHORS   Motohashi,H., Shavit,J.A., Igarashi,K., Yamamoto,M. and Engel,J.D.
  TITLE     The world according to Maf
  JOURNAL   Nucleic Acids Res 25 (15), 2953-2959 (1997)
   PUBMED   9224592
  REMARK    Review article
REFERENCE   10 (bases 1 to 2022)
  AUTHORS   Igarashi,K., Kataoka,K., Itoh,K., Hayashi,N., Nishizawa,M. and
            Yamamoto,M.
  TITLE     Regulation of transcription by dimerization of erythroid factor
            NF-E2 p45 with small Maf proteins
  JOURNAL   Nature 367 (6463), 568-572 (1994)
   PUBMED   8107826
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC165278.4.
            
            On Feb 4, 2022 this sequence version replaced NM_001304832.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY740342.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-299               AC165278.4         21557-21855
            300-366             AC165278.4         30122-30188
            367-2022            AC165278.4         30576-32231
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.7 cM"
     gene            1..2022
                     /gene="Maff"
                     /note="v-maf musculoaponeurotic fibrosarcoma oncogene
                     family, protein F (avian)"
                     /db_xref="GeneID:17133"
                     /db_xref="MGI:MGI:96910"
     exon            1..299
                     /gene="Maff"
                     /inference="alignment:Splign:2.1.0"
     exon            300..366
                     /gene="Maff"
                     /inference="alignment:Splign:2.1.0"
     CDS             331..801
                     /gene="Maff"
                     /note="V-maf musculoaponeurotic fibrosarcoma oncogene
                     homolog F"
                     /codon_start=1
                     /product="transcription factor MafF"
                     /protein_id="NP_001291761.2"
                     /db_xref="GeneID:17133"
                     /db_xref="MGI:MGI:96910"
                     /translation="MAVDPLSSKALKVKRELSENTPHLSDEALMGLSVRELNRNLRGL
                     SAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRL
                     ELDALRGKCEALQGFARSVAAARGPAALVAPASVITIVKSAPGPAPAADPAPCS"
     exon            367..2022
                     /gene="Maff"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1995..2000
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Maff"
                     /note="hexamer: AATAAA"
     polyA_site      2022
                     /gene="Maff"
                     /note="major polyA site"
ORIGIN      
        1 agaatagagc agaggttagc gagccagtct tctcctggcc acctggtgga tctgggaacc
       61 tagtacatgg gagtccttcc ttagccccaa gttttccggc tcagtatgga ctgtccaccc
      121 ctggattgtc ccattcttcc agtctcagga gaaacaggca aggccagaaa gtttgtgaca
      181 gattggagaa cacaaggctc ccggactatt ctgttggcga ctgtggttgg tctgggtgtc
      241 tgaggctgca cctgctgggt ccaggaggat ggcatgaggc ccactgtcac actcctcagg
      301 tctccagccc agaggtcatc ttctgcgaaa atggctgtgg atcccttatc tagcaaagcc
      361 ctgaaggtca agcgcgagtt gagcgagaac acgccgcacc tgtcggatga agcgctgatg
      421 gggctgtcgg tgcgcgagct gaaccgcaac ctgcgcgggc tgtcggcgga ggaggtgacg
      481 cggctgaagc agcggcgccg cacactcaag aaccgcggct acgcggccag ctgccgcgtg
      541 aagcgcgtgt gccagaagga ggagctgcag aagcagaagt ccgagctgga gcgcgaggtg
      601 gacaagctgg cgcgcgagaa cgccgccatg cgcctggagc tcgacgcgct gcgcggcaag
      661 tgtgaagcgc tgcagggctt cgcgcgctcc gtggccgccg cccgcgggcc cgccgcactg
      721 gtggcgcccg ccagcgtcat caccatcgtc aagtcggcgc cgggcccagc ccctgctgct
      781 gaccccgccc cctgctccta gtacccgccc ccaccccacc acacccctcg gaggccactc
      841 ccttcttcaa gtgcctgagt tccttctgct tcccattcct ttcctctgcc actcgttgta
      901 gtgacttcac attcctttcc tgggctctga ctcttgcagg cccccaaact gggacctgat
      961 ggccctgggg aggggcaact ttgctaagtt gggggtgggg ggaggcgtta gggttctaag
     1021 tttccctggg ctgaaagtcc ggctcaaatt gaaaatgagg tcgtgtggcc agaaggagag
     1081 ctggtggaag aggctttgga ttgtgccagc atgcccttcc gaccctccca ggacccagga
     1141 ctaggtgtgg ccttgtgaga ctgtcctgct gggaagcaga cctcccaact gtgcttgaga
     1201 cttgggaatg ccaggctttc ccaagctaag agtctttgga acggatcaat ggagctcagt
     1261 tgacacatgg ggaagctgtc aggcaaaacg acctaaggcc actgagcacg gaattgttga
     1321 gctgcaaacc caagtggggc cttcttacag ctgccttaat gaacattcca agcgtggctt
     1381 tcacaggggg aacagtaccc cgggactgaa taacatggta ggagagcctc ccgggcctgg
     1441 gagacagctg tgtggtgggg aaagaagctg aaggagagag aaggtgacac aaagggttga
     1501 ggtgaggagc tggccagcca gagaaagatg gatggagacg accactggta gagagaggca
     1561 aacactacag tcctgatgca ggagaatggg gtgggtgtgg ggtgacctgg agttacggct
     1621 tccactttgg tccagagtat ctgtggtggt ctgagggtgc tgatcactgt ccccctggga
     1681 agtccagccc tagcaccttc ccaacactgt atacagctga ctcttccaca ctcttattta
     1741 ttgcacgaat ctaagttatt ctcaccagcc agagtccagc tcctcttccc tgggaaatac
     1801 gtgggccctg agctggactt atattttata tctacaaata aatcacattt aatcttatat
     1861 ttagggagag ctgggtggca acaataggtt ttttttttaa aaaaaaaaaa aaatttgcgc
     1921 agctcccaga gtttatttat tttctgactt caagtgagcc agttatctgc cttgagtatt
     1981 ttgtagactt tctgaataaa gtcaagttct ctttttccac aa
//
