LOCUS       NM_001159940            2302 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus mab-21-like 4 (Mab21l4), transcript variant 2, mRNA.
ACCESSION   NM_001159940
VERSION     NM_001159940.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2302)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2302)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK009193.1 and AK081300.1.
            
            [WARNING] On Jul 31, 2024 this sequence was replaced by
            NM_001159940.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009193.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-894               AK009193.1         1-894
            895-2302            AK081300.1         774-2181
FEATURES             Location/Qualifiers
     source          1..2302
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 47.03 cM"
     gene            1..2302
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /note="mab-21-like 4"
                     /db_xref="GeneID:71874"
                     /db_xref="MGI:MGI:1919124"
     exon            1..69
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            70..819
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             291..1649
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /note="uncharacterized protein C2orf54 homolog"
                     /codon_start=1
                     /product="protein mab-21-like 4"
                     /protein_id="NP_001153412.1"
                     /db_xref="CCDS:CCDS15185.1"
                     /db_xref="GeneID:71874"
                     /db_xref="MGI:MGI:1919124"
                     /translation="MPGSEMPAPCVFAPDMAEQVPLWHHYLLAIQSRESPRVQDYQRA
                     ENILLTVLERVHALDSRFIVDYSRDLEAFQFALRSSEDPLDVEVLLGVDSEALLIEES
                     EATEPGDGPAICRLGVLKEASGLEPWMTADIFSVSSEDRDKCCGHLVPSKVLCVLKDL
                     LVAAIVHCKHHRLIPPGSLNAANLKEGQMRLSLLVSSGWRKIRFNVVPVVRKKHRVPA
                     LEGAQLKLGFPEGILRRIASHGVDLVPANAQHWRISTGYLLSRLLDALGSLPGHRLDS
                     LSILDRVNLESWQGGSQNHGLTFDHLKTVLLWASTLFPAPEDWADLQGSVYRQLVVLL
                     CCLATRKLPHFLYPEHNLLQDGGLDLGAIYQRVEHFASQPEESLRIHVTHLGPSRPPR
                     IDNGVKALLQLPASDPTYWATAYFDFLLDKFQVFNIQDKDRISAMQNIFQKTKTMGSE
                     NS"
     exon            820..1045
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1199
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1556
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..2302
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2056..2061
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /note="hexamer: AATATA"
     polyA_site      2075
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /note="major polyA site"
     regulatory      2284..2289
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2302
                     /gene="Mab21l4"
                     /gene_synonym="2310007B03Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggtgagactt tccagccgtg aggcagagcc agagactgct tctcctagaa ggccccagct
       61 cctggccagg tactgactca ccccacttca aaggccttgg ccttggttca gctatttaac
      121 ctgctgcgag aagcctgtca ctctggaact ctgcctgtgg agagctgagc cctgcctgca
      181 gacctgctcc tcacctgggc aggtacctct tcctccgagc cagtctacac aagctcgaga
      241 gcggtcccca agagccagcg gggccctgct gcctgctgct cggctcaggg atgcctggct
      301 cagagatgcc tgctccctgt gtctttgctc cagacatggc ggagcaggtg cccctgtggc
      361 atcactacct gttggccatc cagtcacggg agtcaccccg tgtccaggac taccagagag
      421 cggagaatat cttgcttacg gtgctggaac gcgtccatgc cttggactcc cgcttcattg
      481 ttgactattc tagagacctg gaggccttcc agtttgccct gcgttcctca gaggacccac
      541 tggatgtgga ggtgctcctg ggggtggatt cggaggctct cctgatcgag gagtcagaag
      601 ccactgagcc aggggatggc cctgcaatct gtcgcctggg tgtcctcaag gaggcatctg
      661 gcctggagcc atggatgact gctgacatct tcagtgtctc ctcagaggac agagacaagt
      721 gctgtggcca ccttgtaccc agtaaagtcc tgtgtgtcct caaagatctt ctggtggctg
      781 ccattgtaca ttgcaagcac cacaggctca ttccaccagg ttcactgaat gctgctaatc
      841 tgaaggaagg gcagatgcgc ctgtctctgc tggtgtccag tggctggagg aagatccgct
      901 tcaacgttgt gcccgtggtg aggaagaagc accgggtgcc tgccttggag ggggcccagt
      961 tgaagcttgg atttcctgag ggcatcttga gaagaattgc cagccacggg gtggacctgg
     1021 taccagctaa tgcccagcac tggaggatct ccactggcta cctgctcagt cgcctgcttg
     1081 atgcactagg ctccctccct ggccaccgcc tggacagcct ctccattctc gaccgcgtaa
     1141 acctagaaag ttggcaaggt ggcagccaga accatggcct aacttttgac cacctgaaga
     1201 cagtgctgct gtgggcctct acgctgttcc cagcaccaga ggactgggct gacctgcagg
     1261 gctcagtgta ccgccagctg gtggtgctgc tctgctgcct ggctaccagg aagctgcccc
     1321 acttcctgta cccggagcac aacttgctgc aggatggtgg cctggacctt ggcgccatct
     1381 accaacgagt agaacacttc gccagccagc ccgaagagtc cttacgaatc catgtcaccc
     1441 acctgggccc cagccgtcca ccacgcatcg acaatggtgt caaagcgcta ctgcagctcc
     1501 cagccagcga ccctacctac tgggccaccg cctactttga ctttctgcta gataagttcc
     1561 aggtcttcaa catccaggat aaggacagaa tctcagccat gcagaacatc ttccagaaga
     1621 ccaagaccat ggggagtgag aacagctgag ctgggctggg agatccagtg tctacctgtg
     1681 gagctcccta gaacttttgg aaaaggaatg gggaacaggg atgtctcttt gagtgactgg
     1741 tggagggact tagtccctaa ggactcctgt tcaagagatc actgtgagag tctaagtatc
     1801 ctgccctggg gacttgaggc agctgccatg ttccagtctg agtttgaagt ccatgggtat
     1861 atgcttccca gaaacccacc gatccatcca tttgatagcc gaacaggtac agccacgaga
     1921 caacacgggt gcttgctctg ctattctcca cactactcct tggggttgaa atactatgtg
     1981 ttcaaggttg aacacattaa tgctccagtg taccccatgg agagggcccc cctactttct
     2041 gtatctctca atgcaaatat agactcctaa aactatgaaa ggctcatgtg caaaggatgg
     2101 tttcatttca aaccttctct actctcgggt agagagtgtt ctcctggaca gccatctcta
     2161 ctctgcagaa gagggaattc catagctccc cttcccccat accagtctta cctgcttctc
     2221 tgtcactgtg ttctctgttc ccagagttct gtgattcccc atatgcactt atttaatctt
     2281 ctcattaaat gccttaagca gc
//
