LOCUS       NM_197945               4319 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus leucine zipper, putative tumor suppressor family
            member 3 (Lzts3), transcript variant 1, mRNA.
ACCESSION   NM_197945
VERSION     NM_197945.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4319)
  AUTHORS   Laguesse,S., Morisot,N., Shin,J.H., Liu,F., Adrover,M.F.,
            Sakhai,S.A., Lopez,M.F., Phamluong,K., Griffin,W.C. 3rd,
            Becker,H.C., Bender,K.J., Alvarez,V.A. and Ron,D.
  TITLE     Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens
            Drive Alcohol Intake, Seeking, and Reward
  JOURNAL   Neuron 96 (1), 145-159 (2017)
   PUBMED   28890345
  REMARK    GeneRIF: data suggest that Prosapip1 in the NAc is a molecular
            transducer of structural and synaptic alterations that drive and/or
            maintain excessive alcohol use.
REFERENCE   2  (bases 1 to 4319)
  AUTHORS   Peng,Y., Clark,C., Luong,R., Tu,W.H., Lee,J., Johnson,D.T., Das,A.,
            Carroll,T.J. and Sun,Z.
  TITLE     The leucine zipper putative tumor suppressor 2 protein LZTS2
            regulates kidney development
  JOURNAL   J Biol Chem 286 (46), 40331-40342 (2011)
   PUBMED   21949185
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY258870.1, AK148251.1, AK161711.1, CO043440.1, BY636255.1 and
            BY630564.1.
            
            On Mar 22, 2014 this sequence version replaced NM_197945.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219379.13644.1,
                                           SRR7345562.3287341.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BY258870.1         1-41
            42-1215             AK148251.1         1-1174
            1216-1386           AK148251.1         1176-1346
            1387-1979           AK161711.1         1341-1933
            1980-2080           AK148251.1         1878-1978
            2081-3531           AK161711.1         1982-3432
            3532-4245           CO043440.1         16-729              c
            4246-4312           BY636255.1         347-413
            4313-4319           BY630564.1         379-385
FEATURES             Location/Qualifiers
     source          1..4319
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 63.24 cM"
     gene            1..4319
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /note="leucine zipper, putative tumor suppressor family
                     member 3"
                     /db_xref="GeneID:241638"
                     /db_xref="MGI:MGI:2656976"
     exon            1..124
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /inference="alignment:Splign:2.1.0"
     exon            125..287
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /inference="alignment:Splign:2.1.0"
     exon            288..764
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /inference="alignment:Splign:2.1.0"
     exon            765..1619
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1620..4319
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4211..4216
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /note="hexamer: AATATA"
     polyA_site      4243
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /note="major polyA site"
     regulatory      4284..4289
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /note="hexamer: AATAAA"
     polyA_site      4314
                     /gene="Lzts3"
                     /gene_synonym="Prosapip1"
                     /note="major polyA site"
ORIGIN      
        1 gggaggggcc aagagcagag cccggccgcg ccgcgcgccc tgtggggcgg gcttcgggct
       61 gcgccagaga gcgggacagc tagcgccggt gtctgagcct ctgcgccgga ctctgaggca
      121 gtgaaggaga aagctgtagt acgggatggc ttggttggct agtccaaagt cgcgcagctg
      181 cttagggccg agcctggatt tcgagaaaga gccatatggc ccctgcagac ctggcctcgg
      241 agggtcccaa gcttgaggac ccgccggccc cccacctctt tggaaagtgc ccttctggct
      301 taatcatggc gaagctggag acgttacctg tgcgcgctga tccagggagg gatcctctcc
      361 tggcctttgc cccccggcct tctgagcttg gacccccaga tccccgcctg actatgggca
      421 gtgtgggtag tggggtgacc catgctcagg agtttcctat gaaaagcgtg ggcactcgaa
      481 cagggggtgg gggcaaccaa ggcagtttcc ctggtccaag aagcggtggt agcggggcca
      541 acagggagag acctggtcgc tacccatcag aggacaaggt tctcgccaac tctctctacc
      601 tcaatggcga gctgcggggc agtgaccaca cagatgtctg tggtaatgtg gtgggcagca
      661 gtgggggcag cagcagcagt gggggcagcg acaaggctcc accccagtat cgcgaaccca
      721 atcacccacc caagctcctg accacctctg gcaagctaga ccagtgctcg gagccactag
      781 ttcggccatc agccttcaag cctgttgtac ccaagaactt tcattccatg cagaacttgt
      841 gtcctccaca gaccaatggg acccctgagg gacgacaggg ccccgcgggc ctcaaaggcg
      901 gactggacaa gtctcggacc atgaccccag ctggtgggag tgggggcggc ctctcagact
      961 caggccggaa ctcactcaca agcttgccca cctatagctc cagctatagc cagcatctgg
     1021 cacccctcag tgcttccacc agccatatca accgtattgg caccgctggc tatagtagtg
     1081 gcagcagcgg tggggggtca ggctaccagg atctggggac ctctgacagt gggcgggctt
     1141 ccagtaagag tgggtcgtca tcatccatgg ggcggtcagg ccacctggga tccggggagg
     1201 gcggaaatgg gggcctgcca tttgcagcct gttcaccacc ctcgcccagt gcgctgatcc
     1261 aggagctgga ggagcggctg tgggagaagg agcaggaggt ggcagctctg cggcgcagcc
     1321 tggagcagag cgaggcagcc gtggcccagg tgttggagga gcggcagaag gcatgggagc
     1381 gggagctagc cgagctccgg cagggctgca gtgggaagct gcagcaggtg gcccgccgtg
     1441 cccagcgtgc ccagcagggc ctacagctgc aggtgctgcg gttacagcag gacaagaaac
     1501 agctgcagga ggaggcggcc cagctgataa ggcaacggga agagctggag gacaaggtgg
     1561 ccgtctgtca gaaggagcag gccgacttcc tgccccggat ggaggaaact aagtgggagg
     1621 tgtgccagaa ggccggtgag atttccctcc tgaagcaaca actgaaggac tctcaggccg
     1681 atgtgtcgca gaagttgagt gagatcgtgg ggctgcgctc acagcttcgg gagggtaggg
     1741 cctcgctccg ggagaaggag gagcagctgc tcagcttgag ggactccttc ggcagcaaac
     1801 aggccagcct ggagctgagt gaaggcgagc tgccccctgc ctgcctcaag cctgcgctga
     1861 cccccgtgga cctggtcgag ccacaggagg cgctggcctc ctgtgagagt gacgaggcca
     1921 agatgcgccg gcaggctggc gtggcggctg ccgcttctct ggtttctgtt gatggggagg
     1981 tggaggctgg aggagagggt gggacacggg ccctacgcag ggaggtgggg agattgcagg
     2041 ctgagctggc tgctgagcgg cgtgcccgtg agcgccaggg tgccagcttt gcggaggagc
     2101 gccgggtgtg gttggaggag aaggagaagg tcattgagta tcagaaacag ctccagctga
     2161 gttatgtgga gatgtatcag cgcaaccagc agctggagcg gcgacttcgg gagcgtgggg
     2221 cagcaggggg gtccagcacg cctactcccc agcatggaga ggaaaagaaa gcctggaccc
     2281 cctcccgcct ggagcgcatc gagtccactg aaatctgatt ctctacgtgc acaaccttct
     2341 gacacgtgcc ctgtctgaag gtcggagtca ccaatgtccc ttccattcat ctcccttccc
     2401 cacgtgtgct gcacatcccc agaccaaaga ggttctcgaa gcagctgtga ccagcccctc
     2461 cccccacttg tcccccgtcc ttgcagctcc agcactgcct ttgtgggtga ccactccaga
     2521 ccctcctgcc aaggagagca tgggagaggg cagagtacaa tggggtgagg tcccaggcgc
     2581 atggagcaag gctccctttc tggggaagcc tcgtgttgga gatagaggca gcaggcctgc
     2641 gttgccaggg agtaccccag cccctttccc ttcttgggct gctaccgccg ccaccaccgt
     2701 caccaccatc tgtccagtgc tactgtctgt gccctcctag gccacacagc ctgagggagc
     2761 ttgcatgggt ctgcccgtgt cgacagaccc taggctccca gtctctctcc ttcatgtgct
     2821 attctccttc cccaggcaga ttggcagggg aagtgggagc agatggcctg cctgtggttg
     2881 agagggctac ctgcccgacc cctcccccac caaggtatct tgggctccag cctcagagcc
     2941 tggactagtt ctgagcatgt gtccctctgt gtatagtgag gaagtgagag cagaggctgg
     3001 aaactcaatc ccaaggggag atctgccttc ctaccctcgg gaagggtcac ctagaggctt
     3061 ctcagcccca ccctcaccct ctggccagga tcctacaagg ctacatcccc tgctgcttgg
     3121 ttgacccccc caaatccagg gtcactgctc agctctgctt atagctatac ctgcctctta
     3181 ggtcttctgt ttgcccgttt ctgaggtcag atggatggat gtctgatgtc ttcctgtgtt
     3241 ttccctcgat ctctcccctt ggcctccttt cgcactcaca tcttcccagg ctgccttttc
     3301 ttccaagttt cacctttcct cccagcagaa agctctgctt ggcttttggt gcactgctca
     3361 cccccagctc cactggccca agtctgagcc tggggccctt gctttgaggg gccagtccga
     3421 gttggatggg actgccctca aggaacaagg ctaatgtgtg tgtgtatgtt agagagagag
     3481 agagagagag agagagagag agagagagag agagagagag agagagagag agagaaagag
     3541 agagagagag aaagagagag agggaggact actgaccctt gggttgcttg ccagactctt
     3601 gagttggctc atttgtccgg gcagggttgg ctggtatggt catcagtatg ggtcgtgaca
     3661 gtcaatgtca cttccttctc taggatctct cagattctat ctccccaaga caggcaggga
     3721 aattctaatt tctctcttaa gaaagtaaat ttccacttca ccagcaataa caatcagagg
     3781 agacttggcc ctcagtcctt gtatttctct ttttcactct ctcttccacc ccaagatgga
     3841 atcttgggga caggagggag agggttggta actactgtga gcaagtcccc caagccctga
     3901 ccagcctcct cccatgactg gtgactgttt aacaagctgt gcatccccca caaaaatagg
     3961 agtgccctat ttgtagtctc cacctctctg cacagctcct tctgggtggt cctcagcagg
     4021 gttttgacct tgattggcgg ctactctggc aaccactgcc cattcttcta atccctcaca
     4081 atacgtgatt cagaccctga gcctggtcca cagtgactgg gaaaaggcat taacacaaaa
     4141 caaaagagat ggggggagag aaaaatatga acagctttgg aatgtccaac tgcaaaataa
     4201 attatatata aatatataaa tatataaata tatatatcta ccatatgtga tggaaagagt
     4261 tttcattttt cctttcccaa agaaataaaa tggagaaagc ctcttggatg gcaattctg
//
