LOCUS       NM_033322               6689 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus leucine zipper transcription factor-like 1 (Lztfl1),
            transcript variant 1, mRNA.
ACCESSION   NM_033322
VERSION     NM_033322.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6689)
  AUTHORS   Song,G., Sun,M., Zhang,Y., Zhang,B., Peng,M. and Bao,B.
  TITLE     Anti-inflammation of LZTFL1 knockdown in OVA-induced asthmatic
            mice: Through ERK/GATA3 signaling pathway
  JOURNAL   Mol Immunol 167, 16-24 (2024)
   PUBMED   38310669
  REMARK    GeneRIF: Anti-inflammation of LZTFL1 knockdown in OVA-induced
            asthmatic mice: Through ERK/GATA3 signaling pathway.
REFERENCE   2  (bases 1 to 6689)
  AUTHORS   Huang,Q., Li,W., Zhou,Q., Awasthi,P., Cazin,C., Yap,Y.,
            Mladenovic-Lucas,L., Hu,B., Jeyasuria,P., Zhang,L., Granneman,J.G.,
            Hess,R.A., Ray,P.F., Kherraf,Z.E., Natarajan,V. and Zhang,Z.
  TITLE     Leucine zipper transcription factor-like 1 (LZTFL1), an
            intraflagellar transporter protein 27 (IFT27) associated protein,
            is required for normal sperm function and male fertility
  JOURNAL   Dev Biol 477, 164-176 (2021)
   PUBMED   34023333
  REMARK    GeneRIF: Leucine zipper transcription factor-like 1 (LZTFL1), an
            intraflagellar transporter protein 27 (IFT27) associated protein,
            is required for normal sperm function and male fertility.
REFERENCE   3  (bases 1 to 6689)
  AUTHORS   Datta,P., Ruffcorn,A. and Seo,S.
  TITLE     Limited time window for retinal gene therapy in a preclinical model
            of ciliopathy
  JOURNAL   Hum Mol Genet 29 (14), 2337-2352 (2020)
   PUBMED   32568387
  REMARK    GeneRIF: Limited time window for retinal gene therapy in a
            preclinical model of ciliopathy.
REFERENCE   4  (bases 1 to 6689)
  AUTHORS   Collin,G.B., Gogna,N., Chang,B., Damkham,N., Pinkney,J., Hyde,L.F.,
            Stone,L., Naggert,J.K., Nishina,P.M. and Krebs,M.P.
  TITLE     Mouse Models of Inherited Retinal Degeneration with Photoreceptor
            Cell Loss
  JOURNAL   Cells 9 (4), 931 (2020)
   PUBMED   32290105
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6689)
  AUTHORS   Datta,P., Hendrickson,B., Brendalen,S., Ruffcorn,A. and Seo,S.
  TITLE     The myosin-tail homology domain of centrosomal protein 290 is
            essential for protein confinement between the inner and outer
            segments in photoreceptors
  JOURNAL   J Biol Chem 294 (50), 19119-19136 (2019)
   PUBMED   31694913
REFERENCE   6  (bases 1 to 6689)
  AUTHORS   Lord-Grignon,J., Abdouh,M. and Bernier,G.
  TITLE     Identification of genes expressed in retinal progenitor/stem cell
            colonies isolated from the ocular ciliary body of adult mice
  JOURNAL   Gene Expr Patterns 6 (8), 992-999 (2006)
   PUBMED   16765103
REFERENCE   7  (bases 1 to 6689)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 6689)
  AUTHORS   Kiss,H., Darai,E., Kiss,C., Kost-Alimova,M., Klein,G.,
            Dumanski,J.P. and Imreh,S.
  TITLE     Comparative human/murine sequence analysis of the common eliminated
            region 1 from human 3p21.3
  JOURNAL   Mamm Genome 13 (11), 646-655 (2002)
   PUBMED   12461651
REFERENCE   9  (bases 1 to 6689)
  AUTHORS   Kiss,H., Kedra,D., Kiss,C., Kost-Alimova,M., Yang,Y., Klein,G.,
            Imreh,S. and Dumanski,J.P.
  TITLE     The LZTFL1 gene is a part of a transcriptional map covering 250 kb
            within the common eliminated region 1 (C3CER1) in 3p21.3
  JOURNAL   Genomics 73 (1), 10-19 (2001)
   PUBMED   11352561
REFERENCE   10 (bases 1 to 6689)
  AUTHORS   Nishiguchi,S., Sakuma,R., Nomura,M., Zou,Z., Jearanaisilavong,J.,
            Joh,T., Yasunaga,T. and Shimada,K.
  TITLE     A catalogue of genes in mouse embryonal carcinoma F9 cells
            identified with expressed sequence tags
  JOURNAL   J Biochem 119 (4), 749-767 (1996)
   PUBMED   8743579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147312.1, AK054003.1 and BE979461.1.
            
            On Oct 28, 2017 this sequence version replaced NM_033322.2.
            
            Transcript Variant: This variant (1) reprsents the protein-coding
            variant.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026840.1, SRR9219380.69106.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AK147312.1         2-64
            64-1902             AK054003.1         2-1840
            1903-6666           AK147312.1         1779-6542
            6667-6689           BE979461.1         1-23                c
FEATURES             Location/Qualifiers
     source          1..6689
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 74.36 cM"
     gene            1..6689
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="leucine zipper transcription factor-like 1"
                     /db_xref="GeneID:93730"
                     /db_xref="MGI:MGI:1934860"
     exon            1..100
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..997
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /codon_start=1
                     /product="leucine zipper transcription factor-like protein
                     1"
                     /protein_id="NP_201579.1"
                     /db_xref="CCDS:CCDS40818.1"
                     /db_xref="GeneID:93730"
                     /db_xref="MGI:MGI:1934860"
                     /translation="MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKDSRL
                     VEETFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFSQAEKWYLKLQTDI
                     SELENRELLEQVAEFEKAEFVSSSKKPIIDITKPKLVPINEGGTTELLNKEILRLQQE
                     NEKLKSRLKTIEIQAVNALDEKSKLERVLQDLQLDQENQQDLLKAQDLDDLENTVATL
                     RSEFQKTLNDKTENQKSLEENLAAAKHDLLRVQEQLSMAEKELEKKFQQTAAYRNMKE
                     ILTKKNDQIKDLRKRLAKYESED"
     exon            101..225
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            226..420
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            421..481
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            482..553
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            554..619
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            620..697
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            698..874
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            875..978
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            979..6678
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1405..1410
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1430
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="major polyA site"
     regulatory      2700..2705
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2733
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
     regulatory      3467..3472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3494
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
     regulatory      3498..3503
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="hexamer: TATAAA"
     polyA_site      3519
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
     regulatory      6649..6654
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="hexamer: AATAAA"
     regulatory      6659..6664
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
                     /note="hexamer: ACTAAA"
     polyA_site      6669
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
     polyA_site      6678
                     /gene="Lztfl1"
                     /gene_synonym="5530402H04Rik; 6130400H19Rik"
ORIGIN      
        1 gtctccgttc ccattggcaa cgcgcggctt ctaaacaacc tccgttcctc aggccccggt
       61 gccggcctcc ctgtttcctg tcggatccgc cgccaccatg gcagagttgg gcctaaatga
      121 gcaccatcaa aatgaggtca ttaattacat gcgttttgct cgttcaaaaa gaggcttgag
      181 acttaaaacg gtagattcct gctttcagga cctcaaggac agcaggctgg tggaggagac
      241 tttcaccatt gatgaggttt cagaagtcct aaatgggctg caggctgtgg tacacagtga
      301 ggtggagtcc gagctcatca atacagctta caccaatgtc ctgctcctac ggcagctgtt
      361 ctcccaagct gagaagtggt atctaaagct acagacagac atctctgaac ttgaaaacag
      421 agaattatta gaacaagttg ctgaatttga aaaggcagaa tttgtatctt caagtaaaaa
      481 gcccatcata gatatcacaa agcctaaact tgttccaatt aatgaaggtg gaactacaga
      541 gctcctaaac aaggaaattt taagacttca acaagagaat gaaaaactaa agtcaaggct
      601 gaagaccatt gaaatacagg ctgtaaatgc tctggatgag aagtcaaaat tggaaagagt
      661 acttcaagat ttacagctcg atcaagaaaa ccaacaggat ttgctaaagg cccaagactt
      721 ggatgacttg gaaaatacag ttgcaactct taggagtgaa tttcagaaga cacttaatga
      781 caagacagaa aaccaaaaat ctttggaaga gaacctagca gcagccaaac atgacctcct
      841 cagagtacag gagcagctga gcatggctga aaaggagtta gagaagaaat ttcaacaaac
      901 agcagcttat cgaaacatga aagagattct caccaaaaag aatgatcaaa tcaaagacct
      961 acggaaaaga ctggcaaaat atgaatctga agattaaaga ctggagattt tgtctagaac
     1021 ctgccacaca tgaacataca agctatctcc attcacctca ggcatgtatt tagaagcatt
     1081 ttgtcatatt ctgttctttt tccaatgttt aggctttcct tgtaatatta gaactatcat
     1141 tcttatcttc agttctgtaa ttgcgaagag aaaaaaaatg taatgattct tttctattgt
     1201 cccaaatacg cctctgtcat atgctccaga gcctccatgc aagtacagtg agatttcttc
     1261 atggtagaca gcagtttaga gtgggaagaa gagccatcct tttgcgttag tgagtgaact
     1321 ttttaatgtt agagaagctg gtaacatcta tacttgtaca gtccctaagt ataaagataa
     1381 atagtaaagt tattaatatt ttcaaataaa cttttatttt aataacgaaa tcttaattta
     1441 tctaatcatc aaaatgtata aactcatgga aaatatgttt actttccact ctagtcaaca
     1501 tttctaatca gttgtaaggg agaataagct gcaccttgaa cctcagctaa cctttgcatc
     1561 tctccgtcat gaatgctgct tattataggc agacgttttt tgcgtcctta tttaccattg
     1621 gtctgtgtta tgaacagaga agtcagattc atcgtatact ttcacagttt aaaaagcaga
     1681 tggactctga gtacgtgtaa cctttagaat tatttgcaga atatcctttt agcttatatg
     1741 tgaattagaa ttctttcaaa ctttgactca acataaaggc actaagttcc aggttgaact
     1801 ttggtttgta tgtgtataga aaaatggcat tttcaagaga ttttaatatc tccattgatg
     1861 tacttttcct cgggtgacca tatataaagt atcggaaacc agacatgacg cctacaatgt
     1921 gtggtgcggt gatgtggtat gagaataaat aaagaccaca aggcaggtaa aactcagaaa
     1981 gaaagcattt aaccgtcacg tgttaacatg gaggaagtgt tctatttctc aaagcaaaca
     2041 tgtcacatcc tgtgtgaaca ctctaagaga gacttttcca tctccaccaa tagggaattt
     2101 attcccagag aagagtacat tgaccagaga gtacatcttt attattttca ctcacacact
     2161 tcatattagc tttgactata ctgtgagact tttgtaactt tgttaaatac taaacgaaca
     2221 aataataatg aagtgatttt tcccttaaaa aaaaaaaagc tgggaaggca atcttaggat
     2281 gataaatgaa cctgaaaggg aagagagaaa aatatataaa aacaaagcaa catttcctac
     2341 acattttttt tcatccattt gtttgcagtt ggaccgctct tcagtttcac gtagggcttg
     2401 cattgaggat gcactttcac cctgtgtttc tttagcccaa cataattccc tctctgaaat
     2461 tccatttgtg gaccaggatg ttttgaataa gtcagaaacc aaaccttgta actaagtgga
     2521 aaatgtgtct gagaaatggt ttaattgtat tctccctcca cctttctcag ttgaaggcca
     2581 ggaagaaaag acttggtaag acactgcacc acatgtaata cattgctggt tagaattttg
     2641 atttgttttg ttggtggtgg ctttgaaata ttctgtgtag tatgttatac ttgttgaata
     2701 ataaattcaa aagtatttct gaaaccttaa aaactgttaa gtagtaaggt aaacagatgg
     2761 gttgcataac cattgtgatg cctgtcttct acagcatgta ctgcgtaatc actgtgcccc
     2821 tgtctcgtac ctgtctcgtg tggcactgat tctccttttt tccactgttg tgctttgttt
     2881 ttaaactcaa acctcagcaa aatttcacct ggtttcccag ttttaagatt tactgaatca
     2941 tttaactgaa aaggcctgtt tagtctatat attttggctc tctaggaaac tgcttcgagc
     3001 cctaagtgag cggatagtgt ccaggcaact gtggactgtc tgctggtaaa ccatcttaat
     3061 gacactcttg gccagggtgc agcacttaac ctactatgca cagggctctg ggatcagaac
     3121 ccacacaata aaataaaaac aactaaagaa gatgtggctt tgatttaact ttaaattgaa
     3181 gcttttgcaa ttatgattga gacattttgt tcacaaaaat aaaatgcaaa gggttttgtt
     3241 attaatgcct tcaattttgt tattaatatc aatttaaatg gttatttgct ctcatcttac
     3301 atgtgtatct gtctgtgttg aatatatatt taatcatttg tttatgtctt ataaatctta
     3361 tatagaatat tttgctcttt taaatgtgta ataatacttg gtaaagcctt tactatctat
     3421 tatttccact ttgataaact gaatgagatt cttagatatc tttataatta aatgtttgca
     3481 tttttaatac attagattat aaaactttgg tattgtttac cctctggtta tgcataagtg
     3541 cctgtgtcct gagctttgct gttagaaatt taagacatga tttatctcat ataatcaagt
     3601 ctttgaagat aattccatct cagcaagcta aaccaccatc aaagaaacaa aacaaacaaa
     3661 aaccattaaa tatttcctga agggaaatca taaagaaagg tattaggatg gccttgatat
     3721 ctttcatatt gccactaggt cagccattaa aggtaccaca aaatcacctg tttatgtgaa
     3781 ttaatgaaaa tatagtcaga gctgaagagc tggctcacta gttaaaagca catagttatc
     3841 ttgcagagag tctatggcat agagttgaaa cctaattcca ggctcctact tgatggctca
     3901 caaccatctg aaactctagt cccaagggat ctgacacctt cttctgactt ctgcaagcac
     3961 cggggctcat gtggtgctaa gacatacatt tatgcaaaac actcatacac ataaaataaa
     4021 taaatcaaat caatagaaag aaaggaaaga acaggaggaa ggaaagaagg aaggaaggaa
     4081 ggaaagggaa aaaagggaaa agggggggaa agggggaagg ggagagggag atgtatcaat
     4141 ctctgttttc atttctcact gtggccttgg aaaacaaaca agcttattag gattactgta
     4201 catccatgct gagggcttaa ggcactcttc cttaagagtg aagtgcatag gatctgctgc
     4261 atcttggaaa cctcaagact tccctgttgc attgcatgaa attatcagtc atccatctca
     4321 gctttgcttt aaatcctgga agtatgtagg tgactgattt gggacatata gatgctatat
     4381 gtgctttatt tcttcctctc gctgtattac acttgctagg atttctagtt aactagaaat
     4441 ggttgtagaa gacattcttg tttcttttgc ggtcttgggg gaaatgcttt aaaattttaa
     4501 taagaattat atgttcaata ttctattatc agataaggaa gttcttactt tgctaaaacc
     4561 tacaaacagg tgttaaattt ttccaaaatt ctttttctgc atttactgaa atgataatgc
     4621 tttttttttt ttttttcttt ttaaagacaa gagtcatact atatagccca ggctgtcttt
     4681 gaaatcttgc ttttgatgcc ttcatttcct gggcacattt tattttttta aatgttaaac
     4741 tatcctcagt tgttaacagt actgccctta gccatagcag tatgtgggtg ctataggaga
     4801 gtggctctgc ctactagtag gtttttcagg caagtattaa tctgttgcta atcttagatt
     4861 tggaaggatg ccttctgatt ctcccaaagc atagaagtat gggaagctat ctgaagccat
     4921 ctcccactca tatcctttcc tcttgggagg cttccaatgt gctcagaata gattggcgtg
     4981 taaaatataa aaatacttac tatgaggcct agccttggtc tctcagtgaa acagcatctc
     5041 acaactgttg ctgttgttat cctgcctgtt tggatgagct attttccttt tggatatatg
     5101 ggggaggccc aagaagctgg caccttcggc ttactctctt ttgttattga tgtaagtaat
     5161 aaactgcctg actctaaaaa cagctcattg catcttttac catctgtctt agtctgacct
     5221 cgatctcact ttggctgcag ctgtatatgt agttacctct caggaactaa ggaatacaac
     5281 ctacaactgc tacagtagca attgacagcc agccttctgc catctgcact ttgagagctg
     5341 tgcagctgaa gaaaatgcct acccaagttt atgctccctt tgggaagaaa ggaaaaggag
     5401 actgtagcca acagcagtca ccccagatat aaaaatgttc tgtcaggcac agtgtgtgtt
     5461 ctcttcccag ggtctatagc cgttctgttg cacctgagtg agactcctga tgatgccctt
     5521 ccagttgccc tcaggctgcc atcaccaaag ctgaagctca caagtgatgc ccagcattta
     5581 tatgccccag cctgtctacc cctggattct gacctcagtt atgatatgtt atagattgct
     5641 gggtcttaag ttttgcaata ttcatgtcaa aactggtctg gaattttcct tccttggtaa
     5701 acatctcttg aaagctgtca acaatgtttc tgagaccata aatgattaac tttaaaaaac
     5761 aaaacaaaaa caacaacaaa ataatgtttg atctctgatt atattcagcg aaagttttaa
     5821 atacttgaac cagcatttat aagtgcagtg atctgaagga agcccatttt gaagaaaagg
     5881 cagtagagag gaaagagtag gagtgaggta gtgggataat gagcaactgt gtctgtatct
     5941 cttaggacat ctcccaacaa cccagcagag ggtttgcatg actcaggttg ctgctgtttg
     6001 tcctggggtt tctgcagcaa tggaggagtg tcttcaaagt gtacggtgtg aattcagtta
     6061 tcagtgttgt cttgtataaa gttctctata gtcagcaact atctgctgtt tttggtttta
     6121 catcttttcc ttatgctcta agttcttaac acatagtttt ggacctcaaa ataacatttt
     6181 agagttattc taggctcaat agtttttgct ttagataatt attacatttt cctaaatttg
     6241 taattgcttt attctgtcag atcttttaaa taatatatat tcatttttaa gggaatatct
     6301 gatgagtttt ggtaaatgtg aatctccatg tgacctctgc cacaattgag aaaggggata
     6361 ttttatcctt ttcagcccct tgtatcactc ttcctgatct ggtacctgag caaccgctga
     6421 tctgcttttt ctcttgacat cttaatgtac ctttttaaaa attcatatga tagaatcata
     6481 gcctaattgt taaatgtacc ttctttcact caacaaaatg tatttaatat ttaagatctg
     6541 tccttgtctg tgtggatact agcagtatat tccttcaatt gttgagaagt tccctgtagt
     6601 atggtctatc atagtttgtt tattcaacca actctcaaga atattttcaa taaaatttac
     6661 taaatctcat acacaaaaaa aaaaaaaaa
//
