LOCUS       NM_026092                816 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus lysozyme-like 1 (Lyzl1), transcript variant 1, mRNA.
ACCESSION   NM_026092 XM_973744
VERSION     NM_026092.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Khan,M., Jabeen,N., Khan,T., Hussain,H.M.J., Ali,A., Khan,R.,
            Jiang,L., Li,T., Tao,Q., Zhang,X., Yin,H., Yu,C., Jiang,X. and
            Shi,Q.
  TITLE     The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2
            are dispensable for fertility in mice
  JOURNAL   Sci Rep 8 (1), 4975 (2018)
   PUBMED   29563520
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 816)
  AUTHORS   Miyata,H., Castaneda,J.M., Fujihara,Y., Yu,Z., Archambeault,D.R.,
            Isotani,A., Kiyozumi,D., Kriseman,M.L., Mashiko,D., Matsumura,T.,
            Matzuk,R.M., Mori,M., Noda,T., Oji,A., Okabe,M.,
            Prunskaite-Hyyrylainen,R., Ramirez-Solis,R., Satouh,Y., Zhang,Q.,
            Ikawa,M. and Matzuk,M.M.
  TITLE     Genome engineering uncovers 54 evolutionarily conserved and
            testis-enriched genes that are not required for male fertility in
            mice
  JOURNAL   Proc Natl Acad Sci U S A 113 (28), 7704-7710 (2016)
   PUBMED   27357688
REFERENCE   3  (bases 1 to 816)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123048.4.
            
            On Jan 24, 2023 this sequence version replaced NM_026092.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048450.1, CA466175.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC123048.4         31006-31091
            87-250              AC123048.4         33641-33804
            251-409             AC123048.4         34281-34439
            410-488             AC123048.4         46258-46336
            489-816             AC123048.4         47049-47376
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 2.57 cM"
     gene            1..816
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /note="lysozyme-like 1"
                     /db_xref="GeneID:67328"
                     /db_xref="MGI:MGI:1914578"
     exon            1..86
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /inference="alignment:Splign:2.1.0"
     exon            87..250
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..558
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /EC_number="3.2.1.17"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; lysozyme-like protein 1; lysozyme-like protein
                     2; lysozyme d1"
                     /codon_start=1
                     /product="lysozyme-like protein 1 isoform 1 precursor"
                     /protein_id="NP_080368.1"
                     /db_xref="CCDS:CCDS29035.1"
                     /db_xref="GeneID:67328"
                     /db_xref="MGI:MGI:1914578"
                     /translation="MKSVGVFALIISFSIVAESKIYTRCKLAKIFAKAGLDNYGGFAL
                     GNWLCMAYYESHYNTTAENVLEDGSTDYGIFQINSFTWCRNARKHQKNHCHVACSALI
                     TDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSEWKRGCEVS"
     exon            251..409
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /inference="alignment:Splign:2.1.0"
     exon            410..488
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /inference="alignment:Splign:2.1.0"
     exon            489..816
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      673..678
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /note="hexamer: AGTAAA"
     polyA_site      700
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /note="major polyA site"
     regulatory      791..796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /note="hexamer: AATAAA"
     polyA_site      816
                     /gene="Lyzl1"
                     /gene_synonym="1700038F02Rik; Lyc2; Lyzd1"
                     /note="major polyA site"
ORIGIN      
        1 agtgaaggat cacgtgtgcc ttgtgagaat caggaatggc ttcacgggat tcaggaaggt
       61 cctgaaaact agaactcact gtctgagctc tgcttccaac gggtcttcgg gatgaagtct
      121 gttggtgtct tcgccctaat tatcagcttc agcatagtcg cagaatccaa aatctacact
      181 cgatgtaaac tggcaaaaat ctttgcaaag gccggcctgg acaattacgg gggatttgcc
      241 cttggaaact ggctctgcat ggcatactat gagagccact acaacactac agccgagaat
      301 gtcctggagg atggaagcac tgactatggc attttccaga taaacagttt cacatggtgc
      361 agaaatgcaa gaaagcatca gaagaatcac tgccatgttg cctgctcagc cttgatcact
      421 gatgacctca cagatgccat tctctgtgcc aagaaaattg ttaaagagac acaagggatg
      481 aactattggc agggctggaa gaagaactgt gagaacaaag acatgtcaga gtggaagaga
      541 ggatgtgagg tttcctgatc tgcagcaggt gcaagggtgc tttccgtgac ccgtcagact
      601 tgtactgagt atcgctttct ctcagtgccc cttctcagac ttggagaggg aatctaagct
      661 gtattttaag aaagtaaaca tttcccttta catgccgtca tttctctctg acctgagttc
      721 aatgatgtca taataatttc atgatattag tacttgaaaa atcatttcac aatgtctaag
      781 gactggagag aataaacttt tcttctttgt tgtaaa
//
