LOCUS       NM_053247               2607 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus lymphatic vessel endothelial hyaluronan receptor 1
            (Lyve1), mRNA.
ACCESSION   NM_053247
VERSION     NM_053247.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Do,L.N.H., Delgado,E., Lim,C.G., Bkhache,M., Peluzzo,A.M., Hua,Y.,
            Oza,M., Mohsin,S., Chen,H., Autieri,M.V., Kim,S. and Liu,X.
  TITLE     A neuro-lymphatic communication guides lymphatic development by
            CXCL12 and CXCR4 signaling
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39470100
REFERENCE   2  (bases 1 to 2607)
  AUTHORS   Brouillard,P., Murtomaki,A., Leppanen,V.M., Hyytiainen,M.,
            Mestre,S., Potier,L., Boon,L.M., Revencu,N., Greene,A.,
            Anisimov,A., Salo,M.H., Hinttala,R., Eklund,L., Quere,I.,
            Alitalo,K. and Vikkula,M.
  TITLE     Loss-of-function mutations of the TIE1 receptor tyrosine kinase
            cause late-onset primary lymphedema
  JOURNAL   J Clin Invest 134 (14), e173586 (2024)
   PUBMED   38820174
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2607)
  AUTHORS   Sanketi,B.D., Mantri,M., Huang,L., Tavallaei,M.A., Hu,S.,
            Wang,M.F.Z., De Vlaminck,I. and Kurpios,N.A.
  TITLE     Villus myofibroblasts are developmental and adult progenitors of
            mammalian gut lymphatic musculature
  JOURNAL   Dev Cell 59 (9), 1159-1174 (2024)
   PUBMED   38537630
REFERENCE   4  (bases 1 to 2607)
  AUTHORS   Seo,S., Sonn,S.K., Kweon,H.Y., Jin,J., Kume,T., Ko,J.Y., Park,J.H.
            and Oh,G.T.
  TITLE     Primary Cilium in Neural Crest Cells Crucial for Anterior Segment
            Development and Corneal Avascularity
  JOURNAL   Invest Ophthalmol Vis Sci 65 (3), 30 (2024)
   PUBMED   38517430
REFERENCE   5  (bases 1 to 2607)
  AUTHORS   Whitchurch,J.B., Schneider,S., Hilger,A.C., Kollges,R.,
            Stegmann,J.D., Waffenschmidt,L., Dyer,L., Thiele,H., Dhabhai,B.,
            Dakal,T.C., Muller,A., Norris,D.P. and Reutter,H.M.
  TITLE     PKD1L1 Is Involved in Congenital Chylothorax
  JOURNAL   Cells 13 (2), 149 (2024)
   PUBMED   38247840
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2607)
  AUTHORS   Wigle,J.T., Harvey,N., Detmar,M., Lagutina,I., Grosveld,G.,
            Gunn,M.D., Jackson,D.G. and Oliver,G.
  TITLE     An essential role for Prox1 in the induction of the lymphatic
            endothelial cell phenotype
  JOURNAL   EMBO J 21 (7), 1505-1513 (2002)
   PUBMED   11927535
REFERENCE   7  (bases 1 to 2607)
  AUTHORS   Mouta Carreira,C., Nasser,S.M., di Tomaso,E., Padera,T.P.,
            Boucher,Y., Tomarev,S.I. and Jain,R.K.
  TITLE     LYVE-1 is not restricted to the lymph vessels: expression in normal
            liver blood sinusoids and down-regulation in human liver cancer and
            cirrhosis
  JOURNAL   Cancer Res 61 (22), 8079-8084 (2001)
   PUBMED   11719431
  REMARK    GeneRIF: LYVE-1 is not exclusive to the lymph vessels
REFERENCE   8  (bases 1 to 2607)
  AUTHORS   Prevo,R., Banerji,S., Ferguson,D.J., Clasper,S. and Jackson,D.G.
  TITLE     Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic
            endothelium
  JOURNAL   J Biol Chem 276 (22), 19420-19430 (2001)
   PUBMED   11278811
REFERENCE   9  (bases 1 to 2607)
  AUTHORS   Boensch,C., Huang,S.S., Connolly,D.T. and Huang,J.S.
  TITLE     Cell surface retention sequence binding protein-1 interacts with
            the v-sis gene product and platelet-derived growth factor beta-type
            receptor in simian sarcoma virus-transformed cells
  JOURNAL   J Biol Chem 274 (15), 10582-10589 (1999)
   PUBMED   10187853
REFERENCE   10 (bases 1 to 2607)
  AUTHORS   Banerji,S., Ni,J., Wang,S.X., Clasper,S., Su,J., Tammi,R., Jones,M.
            and Jackson,D.G.
  TITLE     LYVE-1, a new homologue of the CD44 glycoprotein, is a
            lymph-specific receptor for hyaluronan
  JOURNAL   J Cell Biol 144 (4), 789-801 (1999)
   PUBMED   10037799
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC184052.2.
            
            On Nov 17, 2006 this sequence version replaced NM_053247.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004726.2, BC038892.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               AC184052.2         128133-128302       c
            171-339             AC184052.2         124939-125107       c
            340-479             AC184052.2         124710-124849       c
            480-776             AC184052.2         119046-119342       c
            777-855             AC184052.2         118178-118256       c
            856-2607            AC184052.2         115956-117707       c
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 57.89 cM"
     gene            1..2607
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /note="lymphatic vessel endothelial hyaluronan receptor 1"
                     /db_xref="GeneID:114332"
                     /db_xref="MGI:MGI:2136348"
     exon            1..170
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /inference="alignment:Splign:2.1.0"
     exon            171..339
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /inference="alignment:Splign:2.1.0"
     exon            340..479
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /inference="alignment:Splign:2.1.0"
     exon            480..776
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /inference="alignment:Splign:2.1.0"
     exon            777..855
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /inference="alignment:Splign:2.1.0"
     exon            856..2607
                     /gene="Lyve1"
                     /gene_synonym="1200012G08Rik; Crsbp-1; Lyve-1; Xlkd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaactctcc atccagcttg gtgattgaac atctgtctcc cttactgcgg gtggccagcc
       61 acagtgcccc ggagggatct gcacaatgct ccagcacact agcctggtgt tactcctcgc
      121 ctctatttgg accactaggc acccagtcca aggtgccgac ctcgtgcaag acctttccat
      181 ttctacatgc agaatcatgg gcgttgccct tgtgggcaga aacaaaaacc cacagatgaa
      241 tttcacagaa gccaacgagg cctgtaagat gctgggactg actctggcca gcagggacca
      301 ggtagagtca gcgcagaaat ctggctttga gacttgcagc tatggatggg ttggagaaca
      361 gttctctgtc atccctcgga ttttctcaaa ccccaggtgt gggaagaatg gcaaaggtgt
      421 cctgatttgg aatgctccct ccagccaaaa gttcaaagcc tattgccaca actcatccga
      481 cacctgggtt aactcctgca ttccagaaat cgttaccaca ttttaccccg tgttggacac
      541 tcaaacaccc gcaacagagt tttctgtcag cagcagcgcc tacttggctt catcccctga
      601 ctccacaaca cctgtttctg ccaccacccg ggctccacct ttgacctcca tggcacggaa
      661 gacaaaaaag atttgtatca cggaagttta tacagaacct atcaccatgg ctacagaaac
      721 agaagcattt gttgcaagtg gagcagcatt caagaacgaa gcagctgggt ttggaggtgt
      781 ccccaccgcc ctgctggtgc tggctctcct cttctttggt gctgccgctg tgctggctgt
      841 ttgctacgtg aaaaggtatg tgaaggcctt ccctttcaca accaagaatc aacagaagga
      901 aatgatcgaa accaaggttg taaaggaaga gaaggctgat gacgtcaacg ctaatgaaga
      961 atcaaagaaa accattaaaa acccagagga ggccaagagt ccacccaaaa ctacggtgcg
     1021 atgcttagaa gctgaagttt agatgcaaga gagtggagaa ggtgcacacg aggcaagttt
     1081 catgccccgg gaaccaaaga agcaagccac tgtcagttcc tgcagaaaaa gactgcagag
     1141 ttcaccagaa ggagccctct ccttactgca gtcttctctg gactctaccc tctggcctcc
     1201 aaccttccca cagcctccct aacccttctg tggctcacag cagaccagag agtagaggga
     1261 gctttcaaag taccaggtcc taaaacagct cctaagctca cactcagaga caggcttcca
     1321 ggttgcctga cccccatgaa aggccagagt ccctgagaca tggccagccc catagttcaa
     1381 aatcttccca cagggaaata caccacctgg ccgtgctctt tggaaccagg cacatgtaaa
     1441 ataaggaaag gaaaacaaca gaaggtcatg gagagcctgg gtgacttgag acttaatctc
     1501 tggaaagcca aaataaacag agcatgagat gggagctggg gccacagata gcagccttgt
     1561 tggctgagac tgtaaataca ggctggggct gagaagcctc tcggttaatt gatctgcagc
     1621 acgtagacag actttctttt ctttttactg ttgctggtgt tctctagaga caaatacacg
     1681 tttataagaa acctaaaagc aggagagccc aggagctgac tcagtggtaa agcacttgcc
     1741 cggcatgtac aaacaaggct tccagtccaa tccccagaat ccactgaccc cacacacaca
     1801 aagaaacaaa cacaagtatg catttccatt ttttacttga attacaggac ccatggctga
     1861 gaaaataact atgttaaaag gttaaaaaaa aggagaaaag tacaaaaaag aaaaaaaaat
     1921 tgtcagataa tctactacaa acagaacact tgagaaaccg aaatgcttgg caccgacagt
     1981 gttaaagagt gcaggttatg tttgaagtct gggatgcttt cacaaacata atgatatatt
     2041 agagggactc agtctaaata tgaagtttac ttatgtttca tgcacacctt agacacttag
     2101 cctggcggta atttcagacg aaaatttaaa aataattttc cacatgagat aaagtctcac
     2161 agtgtgacat ttgcccctgg ggacagcatg ctgacaagca gtttcaggct tggtaaaagt
     2221 ttagttttca gatttttggg ttaaagctat gaggagctat gtacggcatg acattccata
     2281 actgatatta ctcaacacat tctcatgtat agcggagtgt gggctgaagc taatattttt
     2341 ttccagcttt tatatcctta gcttttctac ttccaaacta atttttttgt tgctgagaat
     2401 aatccattca ttttctctaa tacagcaact acttcaacct ttaatttatt attaatgtat
     2461 ttgaaagtgt attattacct ctatgtacca acatatacac tttgtgtgcc tttaacaaat
     2521 acattattag ctctcattct tttccagcaa gaagaacctg agaggagaaa aaaaaatatt
     2581 tgtgccccaa acaaataaag catttag
//
