LOCUS       NM_175215               2974 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus LysM, putative peptidoglycan-binding, domain
            containing 4 (Lysmd4), transcript variant B, mRNA.
ACCESSION   NM_175215
VERSION     NM_175215.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2974)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158751.7 and AK033681.1.
            
            On Jul 17, 2010 this sequence version replaced NM_175215.3.
            
            Transcript Variant: This variant (B) differs in the 5' UTR compared
            to variant A. Both variants A and B encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033681.1, SRR1660813.222500.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AC158751.7         76937-77000         c
            65-2962             AK033681.1         2-2899
            2963-2974           AC158751.7         71076-71087         c
FEATURES             Location/Qualifiers
     source          1..2974
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 36.71 cM"
     gene            1..2974
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /note="LysM, putative peptidoglycan-binding, domain
                     containing 4"
                     /db_xref="GeneID:75099"
                     /db_xref="MGI:MGI:1922349"
     exon            1..86
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            87..369
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..978
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /note="isoform A is encoded by transcript variant B; lysM
                     and putative peptidoglycan-binding domain-containing
                     protein 4"
                     /codon_start=1
                     /product="lysM and putative peptidoglycan-binding
                     domain-containing protein 4 isoform A"
                     /protein_id="NP_780424.1"
                     /db_xref="CCDS:CCDS21350.1"
                     /db_xref="GeneID:75099"
                     /db_xref="MGI:MGI:1922349"
                     /translation="MRQKEVLAKSFQGPAAVCRTPNSHVYMFNNGSGDSGDSSEEESH
                     QVVLRPRGKEHQKNSSQRPGAGTMVLLQRELAQEDSLNKLALQYGCKVADIKKANNFI
                     REQDLYALKSIKIPVRNHGILTETHQELMPLGASSSETRVTLVDLPEDEDAGGATTQG
                     NQLTDFFKGIDENIERAVHSDVFHGDSCCVEAPDQLLLPITQKPVADGADCGIQWWNA
                     VFLMLLIGIVLPVFYLVYFKIQATGEPSNGLNATVVPNGSMTLSPVPGQAPRLAIPVP
                     TLPASDSQVSPTTQAGA"
     exon            370..2974
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2942..2947
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2969
                     /gene="Lysmd4"
                     /gene_synonym="4930506D23Rik"
                     /note="major polyA site"
ORIGIN      
        1 ttggttggct cttagtcccc gcccccggaa gacctgcttt ttgcagccaa tcggcgggcg
       61 cggtggcggt gaagcctggg agcgagttaa gagaaaatga ggcagaagga agtgttagcc
      121 aagagcttcc aaggtccagc tgctgtctgc aggactccaa acagccacgt ttacatgttc
      181 aacaatggca gcggggactc tggggactcc tctgaggaag agtcacatca ggtggtgtta
      241 cgaccccggg gcaaggagca ccagaagaac agcagccaac ggccaggagc aggcaccatg
      301 gttctgctgc agcgggagct ggctcaggaa gacagcctca acaagctggc tctccagtat
      361 ggctgcaaag ttgcagatat caagaaagca aacaacttca tcagagagca agacctgtat
      421 gctttgaagt caatcaagat tccagtgaga aatcatggga ttctcacgga gacccaccaa
      481 gaactaatgc cccttggggc ttcatcctct gagaccaggg tgaccctggt agacctgcct
      541 gaagatgaag atgctggtgg agcaaccact cagggcaacc agctgacaga cttcttcaag
      601 ggcattgatg agaacattga gcgggctgtg cattctgacg tcttccacgg tgacagctgc
      661 tgtgtggagg ccccagatca gctgctgctc cccataaccc agaagccagt agccgatggt
      721 gccgactgtg ggattcagtg gtggaatgcc gtcttcctta tgcttctcat tgggatcgta
      781 ttgccagtgt tctatctcgt ctacttcaaa atacaggcca ccggggagcc ctcaaatggc
      841 ttgaacgcaa ctgttgtccc caatggctcg atgacactga gcccagttcc agggcaggct
      901 cccaggttgg caatcccagt gcctaccctc cccgcttcag acagccaggt cagccctacc
      961 acccaggcag gggcctaagc gcattgtttc ctagagttgg cagactttgg cagttggccc
     1021 ttgtgtaact gtcaccagct gtttgcattt cgcttcctga gatgtgtgga caccatggca
     1081 atctggatgg tctagactga ggaatagctt ggcctaactc aaggatgcag gagcccagac
     1141 atccaccatc ccagcaagag agacatttat atgaaactca cagctcttga agacatgtag
     1201 gggccggctg tgagttcctg tgcagcactc tgtgcaggct cctaagtaga atgtgacaaa
     1261 ggttctgcac tattgctgcc cccagtgttg aatagggttt caatggtggg ctcagagaca
     1321 tgctctgtgt ctagatcaag gtgctatata gtatgtcact gagtttgtca gttgacagcc
     1381 tgacatgtta tgtttgcctc ttcacttggc cccactgagg cagtgcttca gaaatgagaa
     1441 cctgaaatcc aaaccgccac cctctaattt aagctctacc cccagagtca ccctaagagc
     1501 atctctgtgg tggtggctcc ctgggttccc cagttggcat ctgggaagca gctggtattg
     1561 gcgaatggtt tgaagggact acatccacca ttaagcttct gtcacatgga cctttgaagc
     1621 aaactggttg ccatgccagc ccagcattgt taataacagt gagtcccacc ccaccctgat
     1681 catgtgcgcc caaagcagag ttctcccact gcctccttga ctcatctatt ctttgggtcc
     1741 ttagagtaaa cttgcacatg ctgtgtctca gtgtgaaaac cagacacaat gtcagtcagc
     1801 cgtcttttac tgtaacaaaa tcatctccag tgggaaaggt ttatcttggc tcatggtttc
     1861 aatccatggc ctgatttggg gctgggtggc tgggggctat ggtaagaaca ccatgaagga
     1921 gagtgtggta aagcagattg ttcatgtggc agggagagag aaggggagag gagcttgggc
     1981 gcaggcatca ccttcagagt tctgcctgca gtggcctgac ttcctcccac tgggtcccat
     2041 ttcttaaagg acccattcct tcccaacact gagatgagga ccaagccttt aagatactat
     2101 ccaaacccca ccaaggtaac tctggctccg aaaggctgga gagagagatg taggagggta
     2161 caaaatgctc agggtttcct cagccactcc ctgagagcag ttggccatca gtcctgttag
     2221 ggatgttggg gggagggcta agtcagcctg ccttgtcaca gcaggggcag gcagaggtgg
     2281 ctgggagctc agcctgggga ggacaggcta gcaggcttct gggatggtta gcaacttgac
     2341 acataggcct agaaatctga ccagaggagc aggaccttac ttgagctggg cctcctgtct
     2401 gaaaaacaac ccacccaggg tgcagatagc aaatttaaat catcttcaga attgagtatt
     2461 ttgaggcaga aaatgaaccc atgaatcttg gtacaataaa catcttgatt atgtaagtga
     2521 tttctatctg gatgctcaaa gaccgttgtg gctgtgaagt ttctcttaaa tgttatcatt
     2581 aacttcatca ggcagggctc agagtcccgt agggaaatga ttcttttggc agacagagaa
     2641 tgtctatatt ttttctatct tctgtctcaa gtgttgggga cttattacca cctgtatata
     2701 gccctgcgtg ggttcctaag taaaaggtga caagggatct gcagtgtcag ggctcctgag
     2761 gttggatgag gtcaaatgac tatcacagtg tccctgcctg ctgagggcag gggtgggctt
     2821 ggctcagaga tttgtgttct gtgtctaggc agaccatggt gctatgcaat agtatcagta
     2881 tgtcactgag ttttagacat gttacagttt taacttgtat ttctgtattt ttctcaagtg
     2941 gaataaaaca atttcttctg tgaaggaaac atga
//
