LOCUS       NM_030257               3139 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus LysM, putative peptidoglycan-binding, domain
            containing 3 (Lysmd3), mRNA.
ACCESSION   NM_030257
VERSION     NM_030257.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3139)
  AUTHORS   Yokoyama,C.C., Baldridge,M.T., Leung,D.W., Zhao,G., Desai,C.,
            Liu,T.C., Diaz-Ochoa,V.E., Huynh,J.P., Kimmey,J.M., Sennott,E.L.,
            Hole,C.R., Idol,R.A., Park,S., Storek,K.M., Wang,C., Hwang,S.,
            Viehmann Milam,A., Chen,E., Kerrinnes,T., Starnbach,M.N.,
            Handley,S.A., Mysorekar,I.U., Allen,P.M., Monack,D.M.,
            Dinauer,M.C., Doering,T.L., Tsolis,R.M., Dworkin,J.E.,
            Stallings,C.L., Amarasinghe,G.K., Micchelli,C.A. and Virgin,H.W.
  TITLE     LysMD3 is a type II membrane protein without an in vivo role in the
            response to a range of pathogens
  JOURNAL   J Biol Chem 293 (16), 6022-6038 (2018)
   PUBMED   29496999
  REMARK    GeneRIF: Mouse LysMD3 is a type II integral membrane protein that
            co-localizes with GM130+ structures, consistent with localization
            to the Golgi apparatus. LysMD3-deficient mice were born at
            Mendelian ratios and had no obvious pathological abnormalities.
            They also exhibited no obvious immune response deficiencies in a
            number of models of infection and inflammation.  LysMD3-deficient
            mice exhibited no signs of intestinal dysbiosis
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC003322.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003322.1, SRR1660817.1897.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3139
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 43.64 cM"
     gene            1..3139
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /note="LysM, putative peptidoglycan-binding, domain
                     containing 3"
                     /db_xref="GeneID:80289"
                     /db_xref="MGI:MGI:1915906"
     exon            1..131
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            132..396
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            397..3128
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2399..2404
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2421
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /note="major polyA site"
     regulatory      2694..2699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2716
                     /gene="Lysmd3"
                     /gene_synonym="1110030H10Rik"
ORIGIN      
        1 gcggcgacgg cggcgacggt ggcagaagcg gacccagaca ccggagaacc tagagtcggt
       61 catgaacgtc tccggggccg cggctgtggt ggaggacata accgtgtcgc cgcgcccctg
      121 ctagaggaca gctagaacgt catggcgggg aggaatcaga accggacggt ttccctccca
      181 ggaattcagg ccagtggcca tgtacttgct tttggaaatt gtacagacaa tgacatgttg
      241 gaagaagatg ctgaagtcta cgaacttcgg tccaggggaa aggagaaggt tcgaagaagc
      301 gcatcgagag atagacttga tgacattgtt atattaacca aagatatcca ggaaggagac
      361 actctaaacg cagtagccct tcagtactgc tgtacggtag cagatatcaa aagagttaac
      421 aatctcatca gtgatcaaga cttttttgct cttaggtcta tcaaaattcc agttaaaagg
      481 tttagttctt tgactgaaac tcttcatcct ctgaaaggaa gacacatttt acatcctcca
      541 cctgttccgt attttcaaga gcaagacatt gtgccagctg atggttctct ttcttccagt
      601 gagtcagccg gcagtttcct aaaagaagtg gaccgagaca tagaacaaat agtcaagtgt
      661 acagacacca agaaggagaa cctgaatgaa gtcgtgtctg ccttaacagc acaacaggtc
      721 cgatttgaac ctgataacaa aagcattcac cgaaaggatc cgtattacgg agcagactgg
      781 gggattggtt ggtggacagc tgtagtgata atgttgatag tgggtataat aacaccagtg
      841 ttttatctgc tgtattatga aattttagct aaagtggatg ttagtcacca ttcaacagtg
      901 ggttcttcac acttgcatcc aggactcaca cctccaacac agcacagaga gatggaaaat
      961 gaaattggtc caacaaaagg aatacctgtt ggtcagcaag atgaccacaa actatatagg
     1021 caagaccctc aggcacatga tgctcaacac aaaacgtaac agtgagctgc atcagtgtta
     1081 gtggtcatgt gtgcatatgg aatatggtga ctcacatgca tccgacaact gcttcgaagt
     1141 cggaatctag gacatcgaag atggtttgtt tttacctttc taaaaaatcc ctgaactttt
     1201 acaaatggac tgtctatagc acctgcatat gctatattga ggctggtcag gccgtacccc
     1261 tgctatatca gggcttaaag cagaaataat ttaaatgtat gtctaggaat tctaacttag
     1321 aagacgctgt catttttctt actcaagatt agttatgttt aaattttaac ttttaaaaga
     1381 ttacctttta gtttgttgtt catgtcaagg attccaaatg cttacaactg aagaaaattt
     1441 gataccatac ctaccaccaa aatattaatt ataaaagttt taattctaaa attattcctg
     1501 acaccaagta cttaacactt aaatctgaaa ctttaaaaat atgtttagca tatgtgccat
     1561 gaaagcaaat gtagaaacag atatggaaac atagtttata atttgcataa tacaggctaa
     1621 gaaatagata tcttaagacc ccccaaatag tgtcattggg ttggaaactt cccatttgat
     1681 cacacggaca ctgtaattcg tcaagatcta ttccttaaaa aaaggaatcc tttatgacta
     1741 gctctgcaac ctcacctcca cttcttcatt tttaaaaata cttgtgtctg atatttgaag
     1801 gcacttttgt agttctttga tgaagtgtta cacagaaaag tatattcagc aaatccctct
     1861 ttatatactc aacatactta ttgctgttat aaatagtaac ttatgcctta attaacacct
     1921 aacgccttac aaagttactt aacgtaagtt catgtacact tcacaatcaa agtttgtgtc
     1981 agattttatt gaataggcta tcatttcaca ggctatatac atttgtctgt cttcactttt
     2041 gagcataaat gaatgaagga aaaacaaatt tgtacaacct gcctctgaag tcttgcagaa
     2101 gaaaatgatt cattaagcaa aaatgagtaa gcaagacttt tacactagca gtagacgggt
     2161 tgctttattc ggcactctgt tgacctctgc ttttccaaaa agaacctgtc caatttagat
     2221 tatcctccta atgtgcatca tccaatggag aaacatatgc caaggtgtgt ggcgtggtca
     2281 aaagggctta atagtggcat tttctacatc taatgtggga caagcaattt ggctaattag
     2341 tatgtattct aaaaatacac ttttagggag tggggtctga tttgcgtggg ttttgtgaaa
     2401 taaagtgcag accgtaaaat atgtcacatt acctcatttt ttagactcta tttcctaaat
     2461 caatgtttca gctttttaaa cattttgtat aacaaattcc aatcctgata caaggaatta
     2521 ttaatatcta tttgttatat ttgggatttt atatgctttc agaagaaaaa gcattacaaa
     2581 aagactgaca tggaagtcag tcattttaag gcccctacat cagagcagtt ttagaaattt
     2641 ttccttattt agtaataggt acattttgat aaattgatcc ttgagtaaat cttattaaaa
     2701 ataatttttt cacataccat gtgcattttg aaatcagagt gatctttaat tatgttcagt
     2761 gttaacacag ccagtttaca ttttacctat attaagcctg ctgaaaaaaa tcaagtttta
     2821 tagtaaaaaa aaaaaaaaat gcagatttca gggcagaaca ggctacataa cctctttttc
     2881 catcaaatag agttgtgatt cttttatagg tggttttact tggaattgtg atcgaagggt
     2941 ctgatcactt atatttaaag gagtaggtat atttgctggt taaaatagtt tctgtcttga
     3001 gcactctttc tgaaggaaat acaacatata tccttaggac acaaccaagc aatttccttt
     3061 tcctatatat cttagaatca ttaatagaat atgattcgat atgtagaatt atgctttcat
     3121 ctttaaaaaa aaaaaaaaa
//
