LOCUS       NM_001419266            1200 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus Ly6/Plaur domain containing 4 (Lypd4), transcript
            variant 2, mRNA.
ACCESSION   NM_001419266 XM_011250517
VERSION     NM_001419266.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1200)
  AUTHORS   Wang,D., Cheng,L., Xia,W., Liu,X., Guo,Y., Yang,X., Guo,X. and
            Xu,E.Y.
  TITLE     LYPD4, mouse homolog of a human acrosome protein, is essential for
            sperm fertilizing ability and male fertilitydagger
  JOURNAL   Biol Reprod 102 (5), 1033-1044 (2020)
   PUBMED   32040177
  REMARK    GeneRIF: LYPD4, mouse homolog of a human acrosome protein, is
            essential for sperm fertilizing ability and male fertilitydagger.
REFERENCE   2  (bases 1 to 1200)
  AUTHORS   Fujihara,Y., Noda,T., Kobayashi,K., Oji,A., Kobayashi,S.,
            Matsumura,T., Larasati,T., Oura,S., Kojima-Kita,K., Yu,Z.,
            Matzuk,M.M. and Ikawa,M.
  TITLE     Identification of multiple male reproductive tract-specific
            proteins that regulate sperm migration through the oviduct in mice
  JOURNAL   Proc Natl Acad Sci U S A 116 (37), 18498-18506 (2019)
   PUBMED   31455729
REFERENCE   3  (bases 1 to 1200)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1200)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161441.21.
            
            On Mar 30, 2023 this sequence version replaced XM_011250517.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.7833.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               AC161441.21        83696-83962
            268-454             AC161441.21        86037-86223
            455-598             AC161441.21        86621-86764
            599-925             AC161441.21        87951-88277
            926-1200            AC161441.21        88558-88832
FEATURES             Location/Qualifiers
     source          1..1200
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.3 cM"
     gene            1..1200
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /note="Ly6/Plaur domain containing 4"
                     /db_xref="GeneID:232973"
                     /db_xref="MGI:MGI:2687054"
     exon            1..267
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            268..454
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             388..1128
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /note="ly6/PLAUR domain-containing protein 4"
                     /codon_start=1
                     /product="ly6/PLAUR domain-containing protein 4 precursor"
                     /protein_id="NP_001406195.1"
                     /db_xref="GeneID:232973"
                     /db_xref="MGI:MGI:2687054"
                     /translation="MILQAWRSLQLLYLLEAISLLPCTEALLCYEATASAFRAVSLHN
                     WKWLLLRSMVCNQREGCEETVVFIETGTSKGVLSFKGCSSAFSYPPQISYLVSPPGVS
                     IASYSRVCRSYLCNNLTNLEPFVRLKASQPMSTLPSAKSCPSCVGKHDQECLPSFVTT
                     ENCPFAASSCYSSTLKFQAGNLNTTFLIMGCARDSHKLLADFQHIGSIRVTEVINVLD
                     KSEAVSAGHCSQGISWSVLLCLLILLRD"
     exon            455..598
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            599..925
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1200
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1177..1182
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1200
                     /gene="Lypd4"
                     /gene_synonym="4933400F01Rik"
                     /note="major polyA site"
ORIGIN      
        1 agacccactg cgcttgcgcc tgcgcataac ctgggctccg cgcttaggcc tccttcggct
       61 ccccctccat gcctggtgtt tagggcaggc tttttagcct gccttttgcc acgcacatct
      121 gggttacagc acccgggtgt ctgtggcatt cctggctaaa gaaggtggca gaagtgactt
      181 ccagctggac tactgctata cagaggatgt gtcctggagc tggaaaggtg ctttctgccc
      241 agcctggggt gttgggattg cttaatgaaa cagtgaccca cagggaagtg gacagaggat
      301 tcagggattg acaagagcca aacttgagat tccatctgaa actggctcca gagtgacgtg
      361 tcacatccag gaccctgaca cggaaccatg atactgcagg cctggagatc tctgcagctg
      421 ctgtacctct tagaagccat ctctttactg ccttgtactg aagctcttct gtgctatgag
      481 gcgacagcat cagccttcag agccgtgtcc ttgcataact ggaagtggct tctgttgagg
      541 agcatggtgt gcaatcagag agagggctgc gaggagaccg tagtgttcat cgagacgggg
      601 accagtaagg gagtcctgag tttcaaaggc tgcagctccg ccttttctta ccctccacaa
      661 atctcctacc tcgtgtctcc gcccggagtg tccattgcct cctacagccg cgtctgcagg
      721 tcctatctct gcaacaacct aaccaacctg gagccttttg tgagactcaa ggccagtcaa
      781 cccatgtcca cactaccttc tgccaaaagc tgtccaagct gcgtgggcaa gcacgaccag
      841 gaatgtcttc caagctttgt caccacagag aattgcccct ttgctgcttc ctcatgttac
      901 agttccacct taaaatttca agcagggaat ctcaatacca ccttcctcat catgggctgt
      961 gctcgtgact cacacaagct tttagcagat tttcagcaca ttgggagcat ccgagtgact
     1021 gaggtcatca atgtcctaga taagtccgag gctgtcagtg cagggcactg cagtcaaggt
     1081 atctcttgga gtgttctctt atgccttctt atactcctca gagattgacc acccagcagg
     1141 actggaaaaa tatcagaccc tccccttgca taatcaaata aagcctcgga tttctcctcc
//
