LOCUS       NM_148947                676 bp    mRNA    linear   ROD 11-OCT-2024
DEFINITION  Mus musculus lymphocyte antigen 6 family member G5C (Ly6g5c), mRNA.
ACCESSION   NM_148947
VERSION     NM_148947.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 676)
  AUTHORS   Sakurai,N., Fujihara,Y., Kobayashi,K. and Ikawa,M.
  TITLE     CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c
            causes male subfertility in mice
  JOURNAL   Andrology 12 (5), 981-990 (2024)
   PUBMED   36428102
  REMARK    GeneRIF: CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and
            Ly6g5c causes male subfertility in mice.
REFERENCE   2  (bases 1 to 676)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 676)
  AUTHORS   Mallya,M., Campbell,R.D. and Aguado,B.
  TITLE     Characterization of the five novel Ly-6 superfamily members encoded
            in the MHC, and detection of cells expressing their potential
            ligands
  JOURNAL   Protein Sci 15 (10), 2244-2256 (2006)
   PUBMED   17008713
REFERENCE   4  (bases 1 to 676)
  AUTHORS   Mallya,M., Campbell,R.D. and Aguado,B.
  TITLE     Transcriptional analysis of a novel cluster of LY-6 family members
            in the human and mouse major histocompatibility complex: five genes
            with many splice forms
  JOURNAL   Genomics 80 (1), 113-123 (2002)
   PUBMED   12079290
REFERENCE   5  (bases 1 to 676)
  AUTHORS   Allcock,R.J., Martin,A.M. and Price,P.
  TITLE     The mouse as a model for the effects of MHC genes on human disease
  JOURNAL   Immunol Today 21 (7), 328-332 (2000)
   PUBMED   10871872
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087117.9.
            
            On Jun 24, 2019 this sequence version replaced NM_148947.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC145968.1, AJ315552.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               AC087117.9         216911-217037
            128-292             AC087117.9         219284-219448
            293-676             AC087117.9         220407-220790
FEATURES             Location/Qualifiers
     source          1..676
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.59 cM"
     gene            1..676
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /note="lymphocyte antigen 6 family member G5C"
                     /db_xref="GeneID:114652"
                     /db_xref="MGI:MGI:2148974"
     exon            1..127
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..456
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /note="lymphocyte antigen 6 complex locus protein G5c;
                     lymphocyte antigen 6 complex, locus G5C"
                     /codon_start=1
                     /product="lymphocyte antigen 6 complex locus protein G5c
                     precursor"
                     /protein_id="NP_683749.1"
                     /db_xref="CCDS:CCDS28682.1"
                     /db_xref="GeneID:114652"
                     /db_xref="MGI:MGI:2148974"
                     /translation="MLFMAGPAASWSLRPLGLHGVPQALCAVLLTVLVMKTLVLGDTK
                     LEDLHPQSLPLNKYLNCYRCLLETEELGCLLGSDTCLTPLGSSCVTLHIKNSSGFNVM
                     VSDCYSKEQMVHCSYTRASPVFGFWIFYQCCFLDFCNNPDNRKNSMH"
     exon            128..292
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /inference="alignment:Splign:2.1.0"
     exon            293..676
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /inference="alignment:Splign:2.1.0"
     regulatory      656..661
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /note="hexamer: AATAAA"
     polyA_site      676
                     /gene="Ly6g5c"
                     /gene_synonym="G5c; NG33"
                     /note="major polyA site"
ORIGIN      
        1 gaagccatgc tttttatggc aggccctgca gccagctggt ccctgaggcc cctgggactc
       61 catggcgtcc cccaagcctt gtgtgctgtc ctcttaacag tgctggtcat gaagaccttg
      121 gttctcggtg ataccaagct cgaggacctt caccctcagt ccctcccact aaacaagtac
      181 ctgaattgct accgatgtct gctggagacc gaagagctgg ggtgcctcct ggggtctgac
      241 acctgcctga cacctctggg cagcagctgt gtcaccctgc acataaagaa cagcagcggt
      301 tttaatgtca tggtgagcga ctgctacagc aaggagcaga tggtccattg ttcatatacc
      361 cgtgcttccc cggtgtttgg cttttggata ttctatcagt gttgcttcct ggatttctgc
      421 aacaatccgg acaacagaaa gaatagcatg cactagaaca gcaggaaccc gccacgtcct
      481 gccagctaac ctccagactg gatttccatc tgagtccatc aggacaactc caaagccctc
      541 actcactaca gcctacatcg ttgaccccac gttggcctcc cctctccatc catacccaca
      601 atgctctcct acctctattt tgttcagccc cctctttggt ccaaagttcc ccccaaataa
      661 aatagtatgc aaagtg
//
