LOCUS       NM_148939               1165 bp    mRNA    linear   ROD 12-OCT-2024
DEFINITION  Mus musculus lymphocyte antigen 6 family member G5B (Ly6g5b),
            transcript variant 1, mRNA.
ACCESSION   NM_148939
VERSION     NM_148939.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Sakurai,N., Fujihara,Y., Kobayashi,K. and Ikawa,M.
  TITLE     CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c
            causes male subfertility in mice
  JOURNAL   Andrology 12 (5), 981-990 (2024)
   PUBMED   36428102
  REMARK    GeneRIF: CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and
            Ly6g5c causes male subfertility in mice.
REFERENCE   2  (bases 1 to 1165)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1165)
  AUTHORS   Hernandez-Torres,F., Rastrojo,A. and Aguado,B.
  TITLE     Intron retention and transcript chimerism conserved across mammals:
            Ly6g5b and Csnk2b-Ly6g5b as examples
  JOURNAL   BMC Genomics 14, 199 (2013)
   PUBMED   23521802
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1165)
  AUTHORS   Mallya,M., Campbell,R.D. and Aguado,B.
  TITLE     Characterization of the five novel Ly-6 superfamily members encoded
            in the MHC, and detection of cells expressing their potential
            ligands
  JOURNAL   Protein Sci 15 (10), 2244-2256 (2006)
   PUBMED   17008713
REFERENCE   5  (bases 1 to 1165)
  AUTHORS   Mallya,M., Campbell,R.D. and Aguado,B.
  TITLE     Transcriptional analysis of a novel cluster of LY-6 family members
            in the human and mouse major histocompatibility complex: five genes
            with many splice forms
  JOURNAL   Genomics 80 (1), 113-123 (2002)
   PUBMED   12079290
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR974444.18.
            
            On Jun 25, 2019 this sequence version replaced NM_148939.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC131966.1, HE864438.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               CR974444.18        51338-51504         c
            168-296             CR974444.18        51113-51241         c
            297-1165            CR974444.18        49939-50807         c
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.59 cM"
     gene            1..1165
                     /gene="Ly6g5b"
                     /note="lymphocyte antigen 6 family member G5B"
                     /db_xref="GeneID:266614"
                     /db_xref="MGI:MGI:2385809"
     exon            1..167
                     /gene="Ly6g5b"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..694
                     /gene="Ly6g5b"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; lymphocyte antigen 6 complex locus protein G5b;
                     lymphocyte antigen 6 complex, locus G5B"
                     /codon_start=1
                     /product="lymphocyte antigen 6 complex locus protein G5b
                     isoform 1 precursor"
                     /protein_id="NP_683741.1"
                     /db_xref="CCDS:CCDS28683.1"
                     /db_xref="GeneID:266614"
                     /db_xref="MGI:MGI:2385809"
                     /translation="MRARVLVGMLTMVGFAMGKAPVARVRTCHLCLLEDPSLGCISGS
                     EKCTISLPSPCMVITIYKNTTVRFHVRGCGQHHSYRCQERHVIYQSDYLYKADCCQYD
                     YCNSWSSAQHQSTLRGSPGSHLGMPLSASQIKQFYQALNLSLPQPGFHAHKVSEGLES
                     LILPPELGLSIADLRQIYLFLNSSGLLVLPWDRP"
     exon            168..296
                     /gene="Ly6g5b"
                     /inference="alignment:Splign:2.1.0"
     exon            297..1165
                     /gene="Ly6g5b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1144..1149
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ly6g5b"
                     /note="hexamer: AATAAA"
     polyA_site      1165
                     /gene="Ly6g5b"
                     /note="major polyA site"
ORIGIN      
        1 atcagtttct gctcagactg cctgtcaaac ccattctgcc tctgaagatc aagaaaggtg
       61 gggcttgggg gtactttgtg ggagttgctc ctctccccca aattccataa tgagggcccg
      121 cgtgcttgta ggtatgctga ccatggtggg ctttgcgatg gggaaggctc cagttgccag
      181 agtccgtacc tgccacctgt gcctcttaga agacccttcg ctaggctgca tttctggctc
      241 agaaaagtgc accatcagcc ttccatcgcc gtgtatggtg atcaccatct ataaaaatac
      301 tactgttcgc ttccacgtac ggggctgtgg acagcatcat tcctaccgat gtcaagaaag
      361 gcatgtgatc taccaatcag actacttgta taaggctgat tgctgccagt acgattactg
      421 caactcctgg tccagtgctc agcaccagag caccctgcgt gggtccccag gaagccatct
      481 gggcatgccc ctgtcagcgt ctcagataaa acagttttac caggccctga acctctctct
      541 gcctcagcct ggcttccatg ctcataaggt gtctgagggc ctggagtctc tcattctgcc
      601 cccggagctg ggcttgtcca ttgccgacct tcgccaaata tacttgttcc tcaacagttc
      661 aggacttctg gtccttccct gggatagacc ctgatgtgtt ccccttccta gattctgctc
      721 tgtctgagag actcttcctt tgaggggccc agcatcctgc tctgcggtct gtgaacactc
      781 agatcctctg agccctctga tctcttaagc tttctgctct acatggccaa attctgtatg
      841 gcccctggat ctggggctgg tttgtcctcc tccttttcag gaaacttaag gacggttctc
      901 accaaggctg acttgacaat gaatcccatt ttgagtgtca ctgtctccgt gtaccctcag
      961 tctggtcata tgccatatcc gagcctcagc agccaggccc aagggtggac ttgcatacct
     1021 ttacatctgg cacagcgacc tatctcacta tctccaccat cctggtccgc tgtccttggt
     1081 ctcatcattt cacctgactg cctgccttgt gaggggttgt aggggctccc atgtctcctc
     1141 cgtaataaat caaaacttgg caaaa
//
