LOCUS       NM_001099217             823 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus lymphocyte antigen 6 family memberC2 (Ly6c2),
            transcript variant 2, mRNA.
ACCESSION   NM_001099217 XM_001477071 XM_001477088
VERSION     NM_001099217.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 823)
  AUTHORS   Swierczek-Lasek,B., Tolak,L., Bijoch,L., Stefaniuk,M., Szpak,P.,
            Kalaszczynska,I., Streminska,W., Ciemerych,M.A. and Archacka,K.
  TITLE     Comparison of Muscle Regeneration after BMSC-Conditioned Medium,
            Syngeneic, or Allogeneic BMSC Injection
  JOURNAL   Cells 11 (18), 2843 (2022)
   PUBMED   36139418
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 823)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 823)
  AUTHORS   Ramachandran,P., Pellicoro,A., Vernon,M.A., Boulter,L.,
            Aucott,R.L., Ali,A., Hartland,S.N., Snowdon,V.K., Cappon,A.,
            Gordon-Walker,T.T., Williams,M.J., Dunbar,D.R., Manning,J.R., van
            Rooijen,N., Fallowfield,J.A., Forbes,S.J. and Iredale,J.P.
  TITLE     Differential Ly-6C expression identifies the recruited macrophage
            phenotype, which orchestrates the regression of murine liver
            fibrosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (46), E3186-E3195 (2012)
   PUBMED   23100531
REFERENCE   4  (bases 1 to 823)
  AUTHORS   Stier,M.T. and Spindler,K.R.
  TITLE     Polymorphisms in Ly6 genes in Msq1 encoding susceptibility to mouse
            adenovirus type 1
  JOURNAL   Mamm Genome 23 (3-4), 250-258 (2012)
   PUBMED   22101863
REFERENCE   5  (bases 1 to 823)
  AUTHORS   Takikawa,O., Oku,T., Ito,N., Ushio,Y., Yamamoto,N., Yoneda,Y.,
            Tsuji,J., Sanchez-Bueno,A., Verkhusha,V. and Yoshida,R.
  TITLE     Multiple expression of Ly-6C and accumulation of a Ly-6C pre-mRNA
            in activated macrophages involved in rejection of an allografted
            tumor
  JOURNAL   Biochem Biophys Res Commun 226 (1), 247-253 (1996)
   PUBMED   8806622
REFERENCE   6  (bases 1 to 823)
  AUTHORS   Palfree,R.G., Sirlin,S., Dumont,F.J. and Hammerling,U.
  TITLE     N-terminal and cDNA characterization of murine lymphocyte antigen
            Ly-6C.2
  JOURNAL   J Immunol 140 (1), 305-310 (1988)
   PUBMED   3335781
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116498.15.
            
            On Nov 4, 2017 this sequence version replaced NM_001099217.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092082.1, BY226144.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AC116498.15        147494-147525
            33-115              AC116498.15        147785-147867
            116-232             AC116498.15        148838-148954
            233-823             AC116498.15        150714-151304
FEATURES             Location/Qualifiers
     source          1..823
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 34.29 cM"
     gene            1..823
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /note="lymphocyte antigen 6 family memberC2"
                     /db_xref="GeneID:100041546"
                     /db_xref="MGI:MGI:3712069"
     exon            1..32
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /inference="alignment:Splign:2.1.0"
     exon            33..115
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..441
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 2; lymphocyte antigen 6C precursor (Ly-6C);
                     lymphocyte differentiation antigen; lymphocyte antigen
                     6C2; lymphocyte antigen 6 complex, locus C2"
                     /codon_start=1
                     /product="lymphocyte antigen 6C2 isoform 1 precursor"
                     /protein_id="NP_001092687.1"
                     /db_xref="CCDS:CCDS49638.1"
                     /db_xref="GeneID:100041546"
                     /db_xref="MGI:MGI:3712069"
                     /translation="MDSTHATKSCLLILLVALLCAGRAQGLQCYECYGVPIETSCPAV
                     TCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIKDPNIRERTSCCSEDLCN
                     AAVPTAGSTWTMAGVLLFSLSSVILQTLL"
     exon            116..232
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /inference="alignment:Splign:2.1.0"
     exon            233..823
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      803..808
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /note="hexamer: AATAAA"
     polyA_site      823
                     /gene="Ly6c2"
                     /gene_synonym="Ly-6C.2; Ly-6C2"
                     /note="major polyA site"
ORIGIN      
        1 accactgttc ctgaaacctg gtcagagagg aacccttctc tgaggatgga cagtactcac
       61 gctacaaagt cctgtttgct gattcttctt gtggccctac tgtgtgcagg aagagctcag
      121 ggactgcagt gctacgagtg ctatggagtg ccaattgaga cttcctgccc agcagttacc
      181 tgccgcgcct ctgatggatt ctgcattgct caaaacatag aattgattga ggactctcaa
      241 agaaggaaac taaagacccg tcagtgcctt tctttctgcc ctgctggtgt gccaatcaag
      301 gatcctaaca tcagggagag gacttcctgt tgcagcgaag acctctgcaa tgcagcagtt
      361 cccactgcag gcagcacctg gaccatggca ggggtgcttc tgttcagcct gagctcagtc
      421 atcctgcaga ccttgctctg atggtccttc caatgacccc cacccttttc cttttatcct
      481 catgtgcaac cactctttcc tggagtcctc tagtgacaaa ttatatgtta tagaatgtcc
      541 aatgtgggga tagtgtgtgg aacaccctgt ttcaccttta tagcccctgc tgggtaagtg
      601 cccgactcct ctctagggct ttcaaatctg tacttcttgc aatgccattt agttgtggat
      661 ctctattctt ggccctggag gcatgtgccc agcacatgca acaggcagta ttccaaggta
      721 ttatactatc accatccaca cataagtatc tggggtcctg cagggttccc atgtgtgcct
      781 gtcaatgacc cctgctgagt ccaataaaag ctttgttctc cca
//
