LOCUS       NM_029008               3219 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus laeverin (Lvrn), mRNA.
ACCESSION   NM_029008 XM_911283 XM_988298
VERSION     NM_029008.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Tobita,T., Kiyozumi,D., Muto,M., Noda,T. and Ikawa,M.
  TITLE     Lvrn expression is not critical for mouse placentation
  JOURNAL   J Reprod Dev 65 (3), 239-244 (2019)
   PUBMED   30745494
  REMARK    GeneRIF: LVRN is irrelevant to preeclampsia and dispensable for
            normal placentation and embryonic development in mice
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122801.3 and AC132100.3.
            
            On or before Jul 24, 2009 this sequence version replaced
            XM_911283.2, XM_988298.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164133,
                              SAMN01164137 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-839               AC122801.3         46923-47761         c
            840-982             AC122801.3         32985-33127         c
            983-1122            AC122801.3         31263-31402         c
            1123-1249           AC122801.3         23892-24018         c
            1250-1404           AC122801.3         20763-20917         c
            1405-1518           AC122801.3         19458-19571         c
            1519-1662           AC122801.3         17039-17182         c
            1663-1728           AC122801.3         16477-16542         c
            1729-1794           AC122801.3         16323-16388         c
            1795-1967           AC122801.3         15424-15596         c
            1968-2044           AC122801.3         13305-13381         c
            2045-2184           AC122801.3         12642-12781         c
            2185-2240           AC122801.3         10629-10684         c
            2241-2394           AC122801.3         8261-8414           c
            2395-2489           AC122801.3         6877-6971           c
            2490-2597           AC122801.3         4020-4127           c
            2598-2774           AC122801.3         3060-3236           c
            2775-2912           AC122801.3         2748-2885           c
            2913-2988           AC132100.3         127237-127312       c
            2989-3219           AC132100.3         122349-122579       c
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 24.84 cM"
     gene            1..3219
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /note="laeverin"
                     /db_xref="GeneID:74574"
                     /db_xref="MGI:MGI:1921824"
     exon            1..839
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..3129
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /codon_start=1
                     /product="aminopeptidase Q"
                     /protein_id="NP_083284.1"
                     /db_xref="CCDS:CCDS50284.1"
                     /db_xref="GeneID:74574"
                     /db_xref="MGI:MGI:1921824"
                     /translation="MSRPFSSGVYVSRGVALLLAALTAVLLLVLVALASLYGSCAHVQ
                     PSEQGNSRVKNTSLWPPGGQEWALPTPAQEPTVGTSQDLGPPSGPWDHLRLPPWLVPL
                     HYDLELWPWLQPDKLSPPNLTFTGRVNITVRCTVASSRLLLHSFLLNYKQVEVWGPLA
                     QDTRNATVGRVQVEKVWFAPDMQFVVLDLGQSLEPGSRYELSFHFSGQVLQVGLEGLF
                     LNLYHDEDELRALVATQMEPTFARHVFPCFDEPALKATFNITVIHHPGYAALSNMPQL
                     GQSERIDVNGSRWTVTTFHTTPRMPTYLVALVVCDLDHISRTERGKEIRVWARKDDIA
                     SGYLDFAANITGPIFSFLEDLFNISYRLPKTDIVALPIFASGAMENWGLLIFDESSLL
                     LEPEDELTEKRAMILSIIAHEVGHQWFGNLVTMSWWNNIWLNEGFASYFELELTNYFY
                     PKVPMNMIFFFTVLHGILGEDHALESRAVSTAVENFTETSEINRLFDLYTYKKGACMA
                     WMLASFLSPHLFINALKSYLETFSYSNAEQDDLWRHIQMAIGEQNVTHLPATVKGIMD
                     SWTHRGGFPIITVNVSTGVVKQEPFYLDKVENQTLLSHNSTWIVPIFWMKNGIPQPLV
                     WLDKSNMMFPGMKLSDSDSDWVILNFNVTGYYRVNYDELGWKKLSEQLEKDPKAIPVI
                     NRLQLVSDAFALTKNNYIEIETALDLTKYIAEEDEILVWFEVLLNLINREVIYDVNNY
                     ALYPLLKKYLLKRFNSIWNTYSAIIRENVASLQDNYLSLFSLERIFETACWLGLEDCL
                     QLSRELFKKWTAHPETAIPPQIENAVLCSAVALGSDKDWDFLFNLYINTTEEEDESRR
                     RRLVHAMSCSKDPWILNRFMEYAITAVSSNFSETNIIVVVATSEVGRYIAKDFLMDNW
                     VAVTERYGMDWLDALVPVLGRTVSTDQQVTELQHFFSTVLEEHQRVVVQAKLQAMKTK
                     NLQNKKRIARVVEWLRKNT"
     exon            840..982
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1122
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1249
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1404
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1518
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1662
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1728
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1794
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1967
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            1968..2044
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2184
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2240
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2241..2394
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..2489
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2597
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2598..2774
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2775..2912
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2913..2988
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
     exon            2989..3219
                     /gene="Lvrn"
                     /gene_synonym="4833403I15Rik; AP-Q; APQ; Aqpep"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcttcagtc ccagtcttct cgggctccta gaggaggagg gacagaacaa gagcggaggg
       61 actgggaagg tgtcccatcc ttgcacatcc cgtcctgggt ttaacccgct gtctgtcgct
      121 agtctccgag ttctcctacc ccagtctccc gccatgagcc gtcctttcag ctccggcgtc
      181 tatgtgagcc gcggggtggc cctgctgctg gccgcgctga cagccgtgct cctgctggtg
      241 ctagtggctc tggcttcctt gtatggcagc tgcgctcacg tccagccttc ggagcagggt
      301 aactcccggg tgaagaacac ctcattgtgg cctcccggcg gccaggagtg ggcgctacca
      361 acccccgcac aggagcccac ggtggggacc tcccaagact tgggacctcc gtcggggccc
      421 tgggatcatc tgcgcctgcc tccctggctt gtcccacttc actatgatct ggagctgtgg
      481 ccctggctgc agccggataa gctgtcccca ccgaatttga ccttcacggg tcgcgtgaac
      541 atcacggtac gctgcacagt ggcctcctcg agattgttgc tgcatagctt ccttctgaat
      601 tacaagcaag tggaagtgtg gggtcctctg gcccaggaca ctaggaacgc cactgtaggc
      661 cgcgtgcagg tggagaaagt gtggtttgcg ccggacatgc aattcgtggt gctggatctg
      721 ggccaatcct tggagccagg tagcagatat gagctgagtt tccacttctc tggccaggtg
      781 cttcaggttg gcttagaagg gctctttctg aacctctacc atgatgaaga tgagctcaga
      841 gccctggtag cgactcaaat ggagccaaca tttgccaggc atgttttccc ttgttttgat
      901 gagccagctc taaaggcaac ttttaatatt acagttatcc atcatcctgg gtatgcggct
      961 ctttccaata tgccccagct gggtcagtct gaaagaatcg atgtgaatgg aagcagatgg
     1021 actgtcacta ccttccatac cacaccccgc atgccaacgt accttgttgc ccttgttgtg
     1081 tgtgacttag accacatcag cagaactgag agaggcaagg agatacgtgt ctgggcccgg
     1141 aaagacgaca ttgcaagtgg atatttagac tttgctgcaa acatcacagg ccccatcttc
     1201 tcatttctgg aggatctgtt taatatcagt tatcggcttc caaaaacaga tatagttgcc
     1261 ttgcctattt ttgccagcgg cgccatggag aactggggcc tgttgatatt tgacgaatcg
     1321 tccctgctcc tggaacctga ggatgagctg acggagaaaa gagctatgat cttgagcatc
     1381 atcgcccatg aggttgggca ccagtggttt ggaaacctgg tgaccatgag ctggtggaac
     1441 aatatctggc tcaatgaagg ctttgcatct tattttgaac ttgaactaac taactacttc
     1501 tatcctaaag ttcccatgaa tatgatcttt ttttttaccg ttttacatgg aattctcgga
     1561 gaagatcatg ccctggagtc tagagctgtg tccactgcag tggaaaattt cacagaaaca
     1621 agcgaaataa acagactctt tgacttatat acttacaaga agggagcatg catggcctgg
     1681 atgcttgcta gtttcctgag cccgcacttg tttatcaacg cacttaagtc ttatttggag
     1741 acattttctt actcaaatgc tgagcaagat gacctgtgga gacatattca aatggctata
     1801 ggtgagcaga atgtaactca tttgccagca acagtaaaag gcataatgga cagctggaca
     1861 caccggggtg gctttcctat catcacagta aatgtgtcta ctggcgtcgt taaacaagag
     1921 ccgttttatc ttgacaaggt tgaaaatcag acccttctaa gccacaatag tacatggatt
     1981 gtccctattt tttggatgaa aaatggaatc ccacaacctt tagtctggct agataaaagc
     2041 aacatgatgt tccctgggat gaaactttca gattctgaca gtgactgggt gattttaaac
     2101 ttcaatgtga ctggatatta cagagttaat tacgatgagt taggctggaa gaagttaagt
     2161 gagcaacttg aaaaggatcc taaggccatt cctgtcatta acaggctgca gctggtgagc
     2221 gacgctttcg ccttgactaa aaacaattac attgagatcg agacggcact tgatttaacc
     2281 aaatacattg ccgaagaaga tgagatcctg gtgtggtttg aagtcttact gaacttgata
     2341 aacagggaag ttatttatga tgtgaacaac tatgctttat atccactatt gaagaagtat
     2401 ttactaaaga gatttaactc aatatggaat acttattcag ctataattcg agaaaatgtg
     2461 gcatcattac aagacaatta tttatctcta ttttccctgg aaaggatttt tgaaactgcc
     2521 tgttggttgg gtcttgaaga ctgtctccag ctgtccagag aactcttcaa aaaatggacg
     2581 gctcatccag agacagcaat ccctcctcag attgaaaacg cggtcctctg cagtgccgtt
     2641 gctctgggga gtgataagga ctgggacttt ttgtttaacc tttacatcaa tacgaccgag
     2701 gaagaggacg agagccgccg ccgccgtctt gttcacgcaa tgagctgcag taaagacccg
     2761 tggatactta acagatttat ggagtatgcc atcactgcag tttcctccaa ttttagtgaa
     2821 acaaatataa tagttgttgt agcaacatct gaagttggcc ggtacattgc aaaggacttt
     2881 ctaatggaca actgggtagc tgtgactgaa aggtatggaa tggattggct ggatgctcta
     2941 gtgcctgtct tagggaggac cgtcagtaca gatcagcagg tcacagagtt gcagcacttc
     3001 ttcagtactg tgttggaaga gcaccagagg gttgtggttc aagccaaatt acaggcaatg
     3061 aagacgaaga atctgcaaaa caagaagaga attgccaggg tggttgagtg gcttcggaaa
     3121 aacacgtaat ctatggcttc ttgcaggatg cttcttgcag gatgcttctt gcaggatgct
     3181 tcttgcagga tgcttcttgc atctcataat cttgtttac
//
