LOCUS       NM_001361574            3519 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus LUC7-like 3 (S. cerevisiae) (Luc7l3), transcript
            variant 3, mRNA.
ACCESSION   NM_001361574 XM_006534010
VERSION     NM_001361574.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3519)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3519)
  AUTHORS   Charles,C.H., Abler,A.S. and Lau,L.F.
  TITLE     cDNA sequence of a growth factor-inducible immediate early gene and
            characterization of its encoded protein
  JOURNAL   Oncogene 7 (1), 187-190 (1992)
   PUBMED   1741163
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645965.8 and AL645846.12.
            
            On Mar 29, 2018 this sequence version replaced XM_006534010.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.4162.1,
                                           SRR7652917.1068291.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               AL645965.8         4048-4321           c
            275-341             AL645846.12        178945-179011       c
            342-381             AL645846.12        175506-175545       c
            382-526             AL645846.12        173162-173306       c
            527-601             AL645846.12        170825-170899       c
            602-706             AL645846.12        169276-169380       c
            707-868             AL645846.12        167079-167240       c
            869-1152            AL645846.12        166204-166487       c
            1153-1313           AL645846.12        165240-165400       c
            1314-3519           AL645846.12        160393-162598       c
FEATURES             Location/Qualifiers
     source          1..3519
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 58.9 cM"
     gene            1..3519
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /note="LUC7-like 3 (S. cerevisiae)"
                     /db_xref="GeneID:67684"
                     /db_xref="MGI:MGI:1914934"
     exon            1..274
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     CDS             176..1474
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /note="isoform 3 is encoded by transcript variant 3;
                     cisplatin resistance-associated overexpressed protein;
                     luc7-like protein 3"
                     /codon_start=1
                     /product="luc7-like protein 3 isoform 3"
                     /protein_id="NP_001348503.1"
                     /db_xref="CCDS:CCDS88223.1"
                     /db_xref="GeneID:67684"
                     /db_xref="MGI:MGI:1914934"
                     /translation="MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCP
                     AELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRR
                     GHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMK
                     LVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHM
                     GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREE
                     EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRDRRRSRSRDRRRSR
                     SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKKGSDDKKSSVK
                     SSSREKQSEDTNPESKESDTKNEVNGTSEDIKSEGDTQSN"
     exon            275..341
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            342..381
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            382..526
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            527..601
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            602..706
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            707..868
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1152
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1313
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..3519
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3426..3431
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /note="hexamer: AATAAA"
     polyA_site      3455
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /note="major polyA site"
ORIGIN      
        1 atgctgggaa ggtgcccggg cggcggccat tttgtcttct cggctcctct ctggaagagg
       61 cttttcgagc ttgagagtgg gccgaggggg cttggttcgg cggccgggcg gctggtgggg
      121 ttttttatcg ggtgggtgct agggctggcg tgagcagccg cccggaggaa gcaccatgat
      181 ttctgccgcg cagttgctgg atgagttaat gggccgggac cgaaacctcg ccccggatga
      241 gaagcgcagc aacgtgcgct gggaccacga gagcgtttgt aaatattatc tctgcggttt
      301 ttgtcctgcg gaattgttca caaatacccg ttctgatctt ggtccatgtg aaaaaattca
      361 tgatgaaaat ctaagaaaac agtatgagaa gagttctcgc tttatgaaag ttggctatga
      421 gagagatttt ttgcgatact tacagagttt acttgccgag gtagagcgca gaattagacg
      481 aggtcatgct cgtttggcat tatctcaaaa tcagcagtct tctggggctg ctggtccaac
      541 aggcaaaaat gaagaaaaaa ttcaggttct gacagacaaa attgatgtgc ttctacagca
      601 gattgaagag ttaggatctg aaggaaaggt agaagaagcc cagggaatga tgaaattggt
      661 tgaacagtta aaggaagaga gagaattact aagatctaca acctcgacta tagaaagttt
      721 tgctgcccaa gaaaaacaga tggaagtttg tgaagtgtgt ggagcctttt tgatagtagg
      781 agacgcccag tcccgagtag atgaccatct gatgggaaag caacacatgg gctatgccaa
      841 aattaaagcc actgtggaag aattaaaaga aaagttaaga aaaagaacag aggaacctga
      901 tcgggatgaa cgtctcaaaa aagagaagca agaaagagag gaaagagaaa aagagcggga
      961 gagagaaaga gaagaacggg aaagaaaaag acgaagagaa gaggaagaaa gggaaaaaga
     1021 aagagctcgt gacagagaaa ggagaaagag aagtcgttca cggagtagac actcaagccg
     1081 aacttctgac cggagatgca gcaggtctcg ggaccacaaa agatcacgga gtagagacag
     1141 aaggcgaagc agaagtagag atcgacgaag aagcagaagc catgacagat cagaaagaaa
     1201 acatagatct cgcagtcggg atcgaagacg gtcaaaaagc cgagatcgaa agtcatataa
     1261 gcacaggagc aaaagtcggg acagagaaca agatagaaag tccaaggaga aagaaaagaa
     1321 gggatctgat gataaaaaga gtagtgtgaa gtccagtagt cgagaaaagc agagtgaaga
     1381 cacaaaccct gaatcgaagg aaagtgacac taagaatgag gtcaatggga ccagtgaaga
     1441 cattaaatct gaaggtgaca ctcagtccaa ttaaaactga tctgataaga cctcagatca
     1501 gacagaggta agtgtattgt ttctcacttt gattagggct ttttgttact gtttgacagt
     1561 gcagcgtaag tatgcacaga tgaagatgga gctaagccga gtaagaagac atacaaaagc
     1621 ctcttctgaa ggaaaagaca gtgtagtcct gcaaaacatt ttgaggtaca ttgttttgtc
     1681 tcagctattt tgtagcagac ttcgtgcccc cattagtgtg cctctttgga aattactgtc
     1741 cacgtatgta atatagtcgc cattgaaaag ttaattatcc tttttttagg gattttgctg
     1801 tcatttcttt ttctttttct tttttttttt aataaaaagg ttgaactgtt ttttttttct
     1861 ttttggtatt aagtccatct tgtgttggta cattggcaga aacatatgct ttaaaactta
     1921 actatttctg aggcacatgt tggactactt tgttttaatt aaactgctag tatttatttg
     1981 tccaggatgt ttctagtttt ttgctttatt gccttgcatt ctaatgcagt ttgttctgta
     2041 actcgagagc cagtagcatt ggattgatgg aagtgtaggg tttatgaatt attgcagctg
     2101 actaccatac ctcacacagc gttggtgttg tgagcggccc atgaaaagcc aaattagaaa
     2161 tcaaggattc agtcaaacta agcaggtatt catgccaggt actcctttct ctacccacat
     2221 ccgtgtttga atgctattgc ctgtgacctt tacgcttaac tgttgtgtat cctttttgtt
     2281 ctttacaaga agcacagagg ggttttttgt gtattgcgtg aaatcttaca aagcctatgt
     2341 taacagaatg gaattttttt tcaactgtgt gtagggatgc agtggtgccc agaattagat
     2401 atctttaaag aattttaaat acaataaaca cttcatatta cccgccttgt tacattcagt
     2461 gcaattctca agtctttaag aggtatgtgt ttaatgtttc ctactgtgta ggagaatttg
     2521 cagtcagcca tagtatagag gaataatcac tggctgagac atcgaaagca acagcatcta
     2581 gccaggacag acacttggat cagtgacaca aagaactgat tgactatcag atgaggttgg
     2641 gttcttaaag aactgtttca agctaggttt tatagatatt cttaaaacct ctaactgttc
     2701 aatcttcggg ctagtggtgt gggatgaaat attcctaatg aaaggaagta ccaattagtt
     2761 gatttattgg tggcattcct gttttagaaa agcagtgtag ttctgtctgt gtgaaccatt
     2821 cactcatagg cagcacacac aggcacatgg ctctaagcac cacactgatt gattgatgcc
     2881 ttgatgtaaa aacagtacat tttatataca cgtgtcatgg ttagcagtta gcgactgggc
     2941 caacacttag tcataaaagt ttacctttta tatgctgtct aattatcaat tttccccaaa
     3001 ttttgcattg taggactact gttgaagagt ttttgaagaa tactgaaaac ggaataaagt
     3061 gaagatcaac attaaaatga ggtgaaagaa agctatagtg gcatagaaaa agtataaagc
     3121 tcagttagtt atttggtttt tttattatta ttattaaaaa ttaattcagg actgttgtga
     3181 cctaccagat ttcagaacat gtgttaatag cacatatgcc actttgaaaa cttaggtcct
     3241 gtatcatatt ttttctttaa gactttttaa gaaatattac ctaaacatgt ggcttgctca
     3301 gtgtttactt gcaagttttc agtcttggac tttgaagcca ggattccacg ttagtgctca
     3361 tgtggagcag actggggctc cgttttacac ttgtgctctc cttagccttt ggatttagaa
     3421 gtgaaaataa agtatctctg acttcctgtt gcagagttga ttgtctgtgt cattgaaagg
     3481 ctcagtgctg ctctcttcca ataaagtgac gactccaac
//
