LOCUS       NP_001348503             432 aa            linear   ROD 28-APR-2025
DEFINITION  luc7-like protein 3 isoform 3 [Mus musculus].
ACCESSION   NP_001348503 XP_006534073
VERSION     NP_001348503.1
DBSOURCE    REFSEQ: accession NM_001361574.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 432)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 432)
  AUTHORS   Charles,C.H., Abler,A.S. and Lau,L.F.
  TITLE     cDNA sequence of a growth factor-inducible immediate early gene and
            characterization of its encoded protein
  JOURNAL   Oncogene 7 (1), 187-190 (1992)
   PUBMED   1741163
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645965.8 and AL645846.12.
            
            On Mar 29, 2018 this sequence version replaced XP_006534073.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.4162.1,
                                           SRR7652917.1068291.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 58.9 cM"
     Protein         1..432
                     /product="luc7-like protein 3 isoform 3"
                     /note="cisplatin resistance-associated overexpressed
                     protein; luc7-like protein 3"
                     /calculated_mol_wt=51319
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0000250|UniProtKB:O95232; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Site            3
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O95232; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Region          4..246
                     /region_name="LUC7"
                     /note="LUC7 N_terminus; pfam03194"
                     /db_xref="CDD:460842"
     Site            110
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O95232; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Site            115
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O95232; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Site            231
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:O95232; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Region          234..432
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Site            420
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Site            425
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     Site            431
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17242355,
                     ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q5SUF2.1)"
     CDS             1..432
                     /gene="Luc7l3"
                     /gene_synonym="3300001P08Rik; Luc7a"
                     /coded_by="NM_001361574.1:176..1474"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS88223.1"
                     /db_xref="GeneID:67684"
                     /db_xref="MGI:MGI:1914934"
ORIGIN      
        1 misaaqllde lmgrdrnlap dekrsnvrwd hesvckyylc gfcpaelftn trsdlgpcek
       61 ihdenlrkqy ekssrfmkvg yerdflrylq sllaeverri rrgharlals qnqqssgaag
      121 ptgkneekiq vltdkidvll qqieelgseg kveeaqgmmk lveqlkeere llrsttstie
      181 sfaaqekqme vcevcgafli vgdaqsrvdd hlmgkqhmgy akikatveel keklrkrtee
      241 pdrderlkke kqereereke rerereerer krrreeeere kerardrerr krsrsrsrhs
      301 srtsdrrcsr srdhkrsrsr drrrsrsrdr rrsrshdrse rkhrsrsrdr rrsksrdrks
      361 ykhrsksrdr eqdrkskeke kkgsddkkss vksssrekqs edtnpeskes dtknevngts
      421 ediksegdtq sn
//
