LOCUS       NM_138680               2833 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus LUC7-like 2 (S. cerevisiae) (Luc7l2), transcript
            variant 1, mRNA.
ACCESSION   NM_138680
VERSION     NM_138680.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2833)
  AUTHORS   Howell,V.M., Jones,J.M., Bergren,S.K., Li,L., Billi,A.C.,
            Avenarius,M.R. and Meisler,M.H.
  TITLE     Evidence for a direct role of the disease modifier SCNM1 in
            splicing
  JOURNAL   Hum Mol Genet 16 (20), 2506-2516 (2007)
   PUBMED   17656373
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124762.4 and AC161147.6.
            
            On Sep 13, 2016 this sequence version replaced NM_138680.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF318301.1, BC056970.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-575               AC124762.4         23258-23832         c
            576-670             AC124762.4         4562-4656           c
            671-769             AC161147.6         170975-171073       c
            770-880             AC161147.6         166828-166938       c
            881-1024            AC161147.6         164683-164826       c
            1025-1201           AC161147.6         163319-163495       c
            1202-1293           AC161147.6         162645-162736       c
            1294-1323           AC161147.6         157300-157329       c
            1324-1515           AC161147.6         152646-152837       c
            1516-2833           AC161147.6         146644-147961       c
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 17.85 cM"
     gene            1..2833
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /note="LUC7-like 2 (S. cerevisiae)"
                     /db_xref="GeneID:192196"
                     /db_xref="MGI:MGI:2183260"
     exon            1..575
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     CDS             515..1693
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative RNA-binding protein Luc7-like 2; CGI-74-like
                     SR-rich"
                     /codon_start=1
                     /product="putative RNA-binding protein Luc7-like 2 isoform
                     1"
                     /protein_id="NP_619621.2"
                     /db_xref="CCDS:CCDS20015.1"
                     /db_xref="GeneID:192196"
                     /db_xref="MGI:MGI:2183260"
                     /translation="MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCC
                     PHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTE
                     VSKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVE
                     KARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF
                     IEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREH
                     RRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR
                     SSKERFRDQDLASRDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI
                     "
     exon            576..670
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            671..769
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            770..880
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1024
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1201
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1293
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1323
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1515
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..2833
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2765..2770
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /note="hexamer: AATAAA"
     polyA_site      2786
                     /gene="Luc7l2"
                     /gene_synonym="4930471C18Rik; CGI59; Cgi74"
                     /note="major polyA site"
ORIGIN      
        1 gtgaacgcgc tcgggagccg ttagggtggg acccttcgta ggaggggcag ggcggagcgc
       61 agcgacgtgg atggcgattg gccgaacccc cacgggaaac gactaggcgc gagctgcgtg
      121 cgcgctcccg tcgcggcggc tgcgagccgc gtcagagctc gcttgctggg ggggggggtt
      181 gacggcttct ggcgggtgtt ggtgtcggga ggaggcgaga gtcggcttag cctgtgtcgc
      241 gtctgtctca ggaaccggac ggagagtgag ggcaccaggg ctcactctct aggggggctg
      301 ccattttccg cgttcacgcc gtcgtgagga gcgcagcccg gactctccac gacccctccg
      361 actccctact cgcgggcctc gaggccgcgg cggccaccga gacagcgccg cacctccccc
      421 accccttccc ctcgtccccc gcccgccagg gcccggccgg tgccccaccc ccgcctgcct
      481 gcccgcccga ccgcccgccc gctacgccgc cgccatgtcg gcgcaggccc agatgcgcgc
      541 tatgctggac cagttaatgg gcacctctcg ggacggagat actactcgtc aacgaatcaa
      601 attcagcgat gacagagtat gcaagagcca ccttctcaac tgttgccccc acgatgtcct
      661 ttctggaaca agaatggatc ttggagaatg cttgaaagtc catgacctgg ctttaagagc
      721 agattatgaa attgcgtcca aagaacaaga ctttttcttt gaacttgatg ccatggatca
      781 tctgcagtca ttcattgcag attgtgatag aagaacagaa gtatctaaga aaagactagc
      841 agaaactcaa gaagagataa gtgctgaagt ggctgcaaag gcagagcgtg ttcatgagtt
      901 aaatgaggaa ataggcaagt tgttggccaa agtggaacaa ctaggagctg aaggaaatgt
      961 ggaagaatct cagaaagtca tggatgaagt cgagaaagca cgggcaaaga aaagagaagc
     1021 agaggaagtt tatcggaact ctatgccagc ttccagcttc cagcagcaga aacttcgtgt
     1081 ctgcgaggtc tgctctgcgt atttaggtct tcatgacaat gacaggcgac tggctgatca
     1141 ttttgggggt aaattgcacc tgggatttat tgaaataaga gagaagctgg aagaattaaa
     1201 gagagttgta gctgagaagc aggagaagag aaaccaggaa cgtctgaaac gaagagaaga
     1261 gagggagaga gaagaacggg agaaactgag gaggtcccga tcacatagca agaatcccaa
     1321 aagatctaga tccagagagc atcgcagaca ccgatctcgc tccatgtcac gagaacgcaa
     1381 gaggaggact cgatccaagt ctcgtgagaa acgccatcgc cacaggtcca ggtccagtag
     1441 ccgaagccgc agccgtagcc accagagaag tcggcacagt tcaagagata ggagcagaga
     1501 gcgatccaag aggagatcct caaaagaaag attcagagat caagacttag catcacgtga
     1561 cagagacagg agttcaagag acagatcacc tcgtgaccga gatcgaaaag ataagaagcg
     1621 gtcctatgag agtgctaatg gcagatcaga agacaggagg agctctgaag agcgtgaagc
     1681 aggggagatc taactagctg tgtacatatc ttcaatcctt aagcttccca tggagttaca
     1741 tgctattgtt tatagttgta aagggtgaca gttctagaca ccgatccagt cagactagat
     1801 gtatagtatc caatgatttg aactgaacct gttttccttc ataaagccta aaactacatc
     1861 catagttttt tgtgaacctg aacataacag tttatatgat gagatactgt tctctattct
     1921 ttcaagttag gagtgatagt gaatgaattg tgttaatgtc ttgcagtttt tgaacatttg
     1981 taaaatattg tcttcttttc tattccaaac agcagcagct ttaggatttt ttttttccat
     2041 tataattctt cttcctttga cttttatatc tcctgatacc tgttcctcca actataagag
     2101 gagagggtga agggaagtat tgtaacttct tttctaaggt tctgttcacg ttggttatta
     2161 gttgattaca gttgagcatt tctactggat tgtgtgctgg agacatttaa acacggggct
     2221 gttttgttag gggcctatag agttggaagt tgaacagctg ttgcattaca tacttttgct
     2281 tttatattga aaatttgaaa tcagacttgc cttgattttt tttttttttt tttgttctaa
     2341 gaaactgcta tgttcagtat attgaggggg gtgggggggc agggactatt tcataatagc
     2401 acttgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtagag tttaaagact
     2461 ataattgtaa aaaaaatgaa aagaatcatc accaccactg taacttgttg atagtaagtt
     2521 gccactagaa ctatttgctg tggttatttt ctattttgta acatcttaac agtgcctttc
     2581 tgtataaggc accaaaggaa gtaaatattt aactctggat ttcagatgaa ttgttgctcc
     2641 acccaaatct cttgctgcct atactatact tcagagctgt agtgagcagc ttctgtaagg
     2701 aaagagtgaa cctgtagaag caactaagag ttgcttggtt tgtatttctt aattgacaag
     2761 cctgaataaa aaccatatgt aaccaacata ctgaaacagc agtttctgca ttaaagatct
     2821 aattacctac tga
//
