LOCUS       NM_028190               4977 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Luc7-like (Luc7l), transcript variant 2, mRNA.
ACCESSION   NM_028190
VERSION     NM_028190.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4977)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4977)
  AUTHORS   Blewitt,M.E., Gendrel,A.V., Pang,Z., Sparrow,D.B., Whitelaw,N.,
            Craig,J.M., Apedaile,A., Hilton,D.J., Dunwoodie,S.L.,
            Brockdorff,N., Kay,G.F. and Whitelaw,E.
  TITLE     SmcHD1, containing a structural-maintenance-of-chromosomes hinge
            domain, has a critical role in X inactivation
  JOURNAL   Nat Genet 40 (5), 663-669 (2008)
   PUBMED   18425126
REFERENCE   3  (bases 1 to 4977)
  AUTHORS   Cazalla,D., Newton,K. and Caceres,J.F.
  TITLE     A novel SR-related protein is required for the second step of
            Pre-mRNA splicing
  JOURNAL   Mol Cell Biol 25 (8), 2969-2980 (2005)
   PUBMED   15798186
REFERENCE   4  (bases 1 to 4977)
  AUTHORS   Kimura,E., Hidaka,K., Kida,Y., Morisaki,H., Shirai,M., Araki,K.,
            Suzuki,M., Yamamura,K.I. and Morisaki,T.
  TITLE     Serine-arginine-rich nuclear protein Luc7l regulates myogenesis in
            mice
  JOURNAL   Gene 341, 41-47 (2004)
   PUBMED   15474286
  REMARK    GeneRIF: Luc7l is thought to play an important role in the
            regulation of muscle differentiation.
REFERENCE   5  (bases 1 to 4977)
  AUTHORS   Tufarelli,C., Frischauf,A.M., Hardison,R., Flint,J. and Higgs,D.R.
  TITLE     Characterization of a widely expressed gene (LUC7-LIKE; LUC7L)
            defining the centromeric boundary of the human alpha-globin domain
  JOURNAL   Genomics 71 (3), 307-314 (2001)
   PUBMED   11170747
REFERENCE   6  (bases 1 to 4977)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK160293.1, CF951283.1 and AC126438.3.
            
            On Feb 24, 2011 this sequence version replaced NM_028190.2.
            
            Transcript Variant: This variant (2) differs in the 3' UTR, which
            results in an early stop codon, compared to variant 1. The encoded
            isoform (2) is shorter than isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.2519104.1,
                                           SRR9219382.11283.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-856               AK160293.1         2-857
            857-1253            CF951283.1         253-649
            1254-4977           AC126438.3         19746-23469         c
FEATURES             Location/Qualifiers
     source          1..4977
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 13.09 cM"
     gene            1..4977
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /note="Luc7-like"
                     /db_xref="GeneID:66978"
                     /db_xref="MGI:MGI:1914228"
     exon            1..182
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1237
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     putative RNA-binding protein Luc7-like 1; Luc7
                     homolog-like"
                     /codon_start=1
                     /product="putative RNA-binding protein Luc7-like 1 isoform
                     2"
                     /protein_id="NP_082466.2"
                     /db_xref="CCDS:CCDS28549.1"
                     /db_xref="GeneID:66978"
                     /db_xref="MGI:MGI:1914228"
                     /translation="MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCC
                     PHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTE
                     LAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVE
                     KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF
                     IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLGRRSGSRTRDRRRSRSRDRR
                     RRRSRSTSRERRKFSRSRSRDRYRRHRSRSRSHSRGHRRASRDRSTKYKFSRERSLRE
                     ESWEYGRNERGPTDWRLENSNGKTASRRSEEKEAGEI"
     exon            183..277
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            278..376
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            377..487
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            488..631
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            632..808
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            809..897
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            898..927
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1095
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..4977
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1416..1421
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1440
                     /gene="Luc7l"
                     /gene_synonym="1810045C04Rik; 2410018D03Rik"
                     /note="major polyA site"
ORIGIN      
        1 ttccccgcgg ccggaaagcg ccgtgcgggc ttcaggctga taggagcgtc tttcctcgtc
       61 gctgtttgcg gcttctctgg tcgagttgtg cggagcttct cggccgtccc cactggccac
      121 catgtccgcc caggcgcaga tgcgggccct gttggaccag ctcatgggca cggctcggga
      181 cggagatgaa accagacaga gggtcaagtt tacagatgac cgtgtctgca agagtcacct
      241 tctggactgc tgcccccatg acatccttgc tgggacgcgc atggatttag gagaatgtac
      301 caaaatccac gacttggctc ttcgagcaga ttatgaaatt gcaagtaaag aaagagacct
      361 gttttttgaa ttagatgcta tggatcactt agagtccttc attgcagagt gtgatcggag
      421 aaccgaactt gccaaaaagc ggctggctga aacacaggag gaaatcagtg cagaagtttc
      481 ggctaaggca gaaaaggtac atgaattaaa tgaagaaata ggaaaacttc ttgctaaagc
      541 tgagcagcta ggagctgaag gaaatgtgga cgaatcccag aagattctta tggaagtgga
      601 gaaagttcgt gcaaagaaaa aagaagcaga ggaagaatat agaaattcca tgcctgcatc
      661 cagttttcaa cagcaaaaac tccgtgtttg cgaggtttgt tcagcttacc ttggtctcca
      721 tgacaatgac cgtcggcttg cagaccactt cgggggcaag ttacacctgg ggttcattca
      781 gatccgggag aagcttgatc agttgaggaa aactgtggct gaaaaacagg aaaaaagaaa
      841 tcaggatcga ttgaggagaa gagaggagag agagcgagaa gagcgcctgg gcaggaggtc
      901 tggatcaaga acccgagatc gcagaaggtc acgctcccgg gatcgtcgac ggaggcggtc
      961 taggtctacc tccagagagc ggcggaagtt ttcccgttcc agatcccgag atagatacag
     1021 gcgccatcgc agccgttccc ggagccacag ccggggtcac cgccgggctt ccagggaccg
     1081 gagtacaaaa tacaagttct ccagggagcg ctcattgaga gaggaatcct gggagtacgg
     1141 gcggaatgaa cgagggccca ctgactggag gctggagaat tccaatggca agactgcatc
     1201 gcggaggtcg gaggagaagg aggctggcga gatctgaatc tggctcaggc gctgtaaata
     1261 gtctgacaaa tgttcggcac cgcctaaatt accctttata tttgctgata caactcatct
     1321 tttgtagtta aaatttctat tgtttggtcc tagctgtgag tttctagagt tgttcagagc
     1381 tgcttctgtg tttggggtta cattgtatag gaacaaataa atctggcggc tgcctcctga
     1441 cagctgtgtt ggggtatctg ctgtcctcta gagtagaggc acttcactag gaccctgcac
     1501 ctgtggagaa aaggctggtg ctgccattac cttaggaaac tgaccaaatg tctgaccaat
     1561 ttgatttttg gcactcccaa cacacttaac tgagccagat gtatgtggct tcgtttcctg
     1621 gttcacgctg catcttagct gctcatgtac tcgctcagtg cagaccatag agcaggttct
     1681 gtggatggga gaaggtggcc atatgacaca gttattttcc taggaagagc tgtatctgtt
     1741 gaaaccttag ctcaggtcag ctacactgca gttccatctt gttacttaag tggaataaag
     1801 acatagatga cctgctaatc aagaagtcct tgagggagag ttacagctta ggtcaggtat
     1861 tctgggaggt ttatactcaa gacaggctaa ctgttacccc ctgagcattt gttgttgctc
     1921 acaaggacca atgccttaag accaaagtga agcccaaata gaaaggatca ctgaatagga
     1981 gttgcttccc ttcacttgtc ttggggaggg aggcattaca gtttgttttt ggagggaacc
     2041 ttagttggtt gtgttaaatg aaaaagcctc cccttctcca tgctgtgctt gtaaaaactt
     2101 agatgctgtt cttgagctgt tgatttgatg gttacacata ggatcttgtg attttgtaat
     2161 gtggctcctg gtgatgctgt gaactcccgt ctgcaggagg atgtatgtgg gtacctgctc
     2221 tgctggtatt gtgaaaacag gcttttcttg atcagctgtc tccatatgca agaaagtagg
     2281 gtggactatc tctggaggca ctggggctcc gtaccatata caggtgccgt gtgtagattt
     2341 cattcacctc tagtcccttg gcctccaggt ggggctcagt ttagctctgc tgacttcctg
     2401 gaataaggtt tgtacctggg cttcttggtc ccaggtagac attttgacta gctgtgacca
     2461 cttatgctgg gcacattttg tttcttggac tcttttgggc cttaactgga cagtcctaac
     2521 cttagatcca acatcagcat gtctggtttg gatccctctc taaatataaa tgtgtgtatg
     2581 gagaaacagc tgttttgctt tattttatca cagagtaaag attctggaaa catttctgtg
     2641 ccatggcctg tagtacccac aggatgatcc ctggggtcac gtggtataca actacaacta
     2701 ctgggtacag taggcagacc ccctgcttac atggcatctt tttgagtggt cggctttccc
     2761 agtctcttgt ggagggtgag ttttacaagg atgttgtggc aaaagttttt tgtcggtttt
     2821 tgaacctttt ctggaaagac agtcttgtct gggcagactt ggatttcagg actcaaggca
     2881 cacttgtttc tgtcccaagt agctgttact aacaagtgtc ccaacatgcc tagatgcttt
     2941 ttttttgttt gttttttgtc ttgtttttgt ttgtttgttt tttgttttgt ttgagacagg
     3001 gttttctgaa tagaaccagc tggcctcaaa ctcagagatc taccttactc tgcctcctga
     3061 tgttttgtta acttttctta agtggagttt cctgtaattt aggtggacat agatgataac
     3121 cagagatctg tttgtggtgt tgttggtagc tctggacatt atgcaagaaa tcatagggtc
     3181 cctgggcagt ggtggcgcat gtctttaatc ccagcgcttg gggggcagag gcaggcagat
     3241 ttttgagttc caggccaacc tggtctacag agagagaccc aggatagcca aggctacaca
     3301 gagaaaccct gtctcgaaaa aaccaaaaag gaaaaaaaat catagggtct tccatctgta
     3361 acccgaggtc tgacacaggt actgattacg aagagcaagc ctccaaggaa gaattgggag
     3421 agccagtagt tttcaaaaac ccagtaacca gtcacccatg ggcccagagc acaggaggtg
     3481 ggtatccagc tcagagagag tagatacacc cttcctgggc cctcttgttc tttctaggct
     3541 tttggtgttg cccagtgcac tgagtgaaga ggttggagtg cactgagtgt tggaggcctc
     3601 ttgaatttcc caatgtccca tggtcattgt aacaggtaaa aggctgggtc ttcccttgga
     3661 tctgtgactc ttggaacttg gcccattgta ttgaaagaat agccacttaa tatccagata
     3721 atgagggcag atgcaggttg cgcctcttgg aggacccatc cccagttcag cagtacttgg
     3781 aagtcagtac ctgagtcgtg tggcttagga atgtcactgt ctgtcaaggc ctgtatggtg
     3841 agccagaagt atccagagtg ggccaggtga aggttaacaa gctgacaatt gcttcaggaa
     3901 gctctgggaa aacttggtta tcctgatggg ggtcccaaca gcaggatcag ttgtctgcgt
     3961 ttgactttac tctgcagtct ggtcctagaa tgtgtgagct ctgtttgttt ccaaaggtag
     4021 ctgtggcctg gcagctttaa gcttacctgg actctaaagc ctcacatttt atacctggca
     4081 tgcactatta gaatacactg aattttagtg tgtactttgt cagtgtcttc tgcctactca
     4141 gttcttaaca cacttccttg ggtctaaatt taaatttact gctaaaatga aagtaattct
     4201 caagatactg ttgttaggtg tgtgacttct agcacatgtt tttttcagaa cagtgatatt
     4261 tatagaatac tgtgatgtat tccagtgata gcaaaatgca acaaagcttc ttataacaaa
     4321 ctcccattat agccacttct gatgggtata agtcagtgac atttatgtgt ccagtgttgt
     4381 gaagtgatca ctgatacaaa gttgcaggat gttcgatcca gacagaaact tcagcccacc
     4441 agttgaaact gactagcttc tcctgagccc cctggcaacc aggaacccgt tttctctcta
     4501 tagtttgctc atttggatat ttcacaaaaa tggactcatg cactgggtgg cctttggtgt
     4561 gttggcttct tccactcaag gtttctacaa aacttggctg tgtgatgtaa tctcattact
     4621 tttatgagta agaaatactc cattctgagt gtaagctacg tatttctcac tgtgatggtt
     4681 aacttgctaa actcgatggg cttagaaacg ccatgagaac acacccctgc gtatgtcagt
     4741 gcaggtgttt ccagggaatt cagtgagaga cccaccaagg atgtgggcgg caccatccta
     4801 tgtgctggta tcctagaatg aagaaaaaag gagggcaaga gctgagcacc agccatctct
     4861 caacttcctg actgcagatg caatgtgacc agctgcctta agttcctgca accatgactt
     4921 cccaccacaa ggactgtacc cttatactgt gagccaaata aaccttccct cagttgc
//
