LOCUS       NM_181470               1784 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus LTV1 ribosome biogenesis factor (Ltv1), mRNA.
ACCESSION   NM_181470
VERSION     NM_181470.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1784)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1784)
  AUTHORS   Temeles,G.L., Ram,P.T., Rothstein,J.L. and Schultz,R.M.
  TITLE     Expression patterns of novel genes during mouse preimplantation
            embryogenesis
  JOURNAL   Mol Reprod Dev 37 (2), 121-129 (1994)
   PUBMED   7545925
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC067062.1.
            
            On Jun 3, 2007 this sequence version replaced NM_181470.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067062.1, AK011491.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 4.72 cM"
     gene            1..1784
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /note="LTV1 ribosome biogenesis factor"
                     /db_xref="GeneID:353258"
                     /db_xref="MGI:MGI:2447810"
     exon            1..110
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..1520
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /note="LTV1 homolog"
                     /codon_start=1
                     /product="protein LTV1 homolog"
                     /protein_id="NP_852135.1"
                     /db_xref="CCDS:CCDS35845.1"
                     /db_xref="GeneID:353258"
                     /db_xref="MGI:MGI:2447810"
                     /translation="MPHRKKKPFIEKKKAVSFHLVHRSQRDPLAADETAPQRVLLPTQ
                     KVNDEERRAEQRKYGVFFDDDYDYLQHLKEPSGPAELIPSTSFATPLCDKTEDPCVYS
                     STGIKLPSSVFASEFEEDVGLLNKAAPVSGPRLDFDPDIVAALDDDFDFDDPENLLED
                     DFILQANKPTGGERMDTESEEDDGHEWEDMDDEEGSDDRSSAGFLSDGGDLSAPGSPQ
                     EAMKKHLFWEEETKSRFTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDVEIGALDNA
                     ELEGTIQVDSNRLQEVLNDYYKEKAENCVKLSTLEPFEDQDLPTNELDESEKEETITV
                     VLEEAKEKWDCESICSTYSNLYNHPQLIKYEPKPKQIHLSSKTGIPLNVLPKKGLTAK
                     QVERMQMINGSDLPKVSTQPRSKDETKEDKRARKQAIKEERKERRVEKKANKLAFKLE
                     KRRQEKELLNLKKNIEGLKL"
     exon            111..242
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            243..413
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            414..501
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            502..637
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            638..887
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1015
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1155
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1208
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1409
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1769
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1745..1750
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1769
                     /gene="Ltv1"
                     /gene_synonym="2610020N02Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtgacgtgct gccctagccc tgtggaccca cgtgtggagc tgccggcagg taccggggag
       61 cggcggttcg gctgccgcgg ttccggagag ggtgtccctg cctcatcatg cctcacagaa
      121 agaaaaagcc ctttatagag aagaagaaag ctgtgtcttt tcacctggtc caccggagcc
      181 agcgagatcc tttagccgca gatgaaactg caccccagag ggttctcttg cctacacaaa
      241 aggtcaatga cgaggaaaga cgggctgagc agaggaagta cggcgtgttc ttcgacgacg
      301 attatgatta cttgcagcac ctgaaggagc cctctgggcc cgcagagctt atccccagca
      361 cctcctttgc cacacccctc tgcgacaaga cagaagaccc ctgcgtatac tcaagcactg
      421 gaattaagtt gccttcatct gtgtttgcat ccgagtttga ggaagatgtt ggattgttaa
      481 acaaagcagc tccagtttca ggacctcgac tggattttga tccagacatc gttgcagctc
      541 ttgatgatga ttttgacttt gatgacccag aaaacctcct tgaagatgac tttattcttc
      601 aggccaacaa gccgacagga ggagagagga tggatacgga gtctgaggaa gacgatggcc
      661 atgagtggga agacatggac gacgaggaag ggagtgatga caggagctct gcaggctttc
      721 tgtcagatgg aggtgaccta tctgcccccg gctcaccgca ggaagccatg aaaaagcacc
      781 tgttttggga agaggaaacc aaaagccgtt tcacagagta ctccatgacc tcctcagtca
      841 tgaggagaaa tgaacagctg actctacacg atgagaggtt tgagaagttt tatgaacagt
      901 atgatgatgt tgaaattgga gctctggata atgcagaatt ggaaggtacc attcaagtgg
      961 acagcaatcg gctgcaggag gttttgaatg actactacaa ggagaaggca gagaattgtg
     1021 taaaattgag tactcttgag ccttttgagg atcaagatct gccaacaaat gagcttgatg
     1081 agtctgaaaa ggaagagacc attactgtag ttcttgagga agccaaagag aagtgggatt
     1141 gtgaatccat ttgcagtaca tactccaatt tatacaacca cccacagctc atcaaatatg
     1201 aaccaaagcc caaacaaatc cacctgtcgt ctaagaccgg aatacctctc aatgtcttac
     1261 ctaagaaagg cctcacagca aagcaggttg aacggatgca gatgatcaat ggcagtgacc
     1321 tacccaaagt gtccacccag cctcgttcca aagatgagac caaagaggat aaaagagcca
     1381 ggaagcaagc cataaaagag gagcggaagg aacgaagagt tgaaaagaaa gctaacaagc
     1441 tagcatttaa actggagaaa agaagacaag aaaaggagct actgaacttg aagaaaaaca
     1501 ttgaaggtct aaagctgtag gtgtgggaca ttcatataag ttatatttcc atgtcagcag
     1561 tcttagttat gctctgtaat taaccaggat ctgaagaggg gtgagcttgc ccctgccatt
     1621 tttatatgca aatagctgag aaaaatagac tatttgtatt ttcatacaag cggttctcct
     1681 gtcagctaac ttgtaaatac tataatgttg taagtttaat attacacgct tatatttccc
     1741 ctgaaataaa tgatttcatg aaagtcaaaa aaaaaaaaaa aaaa
//
