LOCUS       NM_133939                768 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus LSM8 homolog, U6 small nuclear RNA associated (Lsm8),
            mRNA.
ACCESSION   NM_133939
VERSION     NM_133939.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 768)
  AUTHORS   Cajigas,I., Chakraborty,A., Lynam,M., Swyter,K.R., Bastidas,M.,
            Collens,L., Luo,H., Ay,F. and Kohtz,J.D.
  TITLE     Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological
            control in developing forebrain
  JOURNAL   Development 148 (6) (2021)
   PUBMED   33593819
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 768)
  AUTHORS   Wang,X., Li,Z.T., Yan,Y., Lin,P., Tang,W., Hasler,D., Meduri,R.,
            Li,Y., Hua,M.M., Qi,H.T., Lin,D.H., Shi,H.J., Hui,J., Li,J., Li,D.,
            Yang,J.H., Lin,J., Meister,G., Fischer,U. and Liu,M.F.
  TITLE     LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and
            Spermatogenesis in Mice
  JOURNAL   Mol Cell 77 (5), 999-1013 (2020)
   PUBMED   32017896
REFERENCE   4  (bases 1 to 768)
  AUTHORS   Cajigas,I., Chakraborty,A., Swyter,K.R., Luo,H., Bastidas,M.,
            Nigro,M., Morris,E.R., Chen,S., VanGompel,M.J.W., Leib,D.,
            Kohtz,S.J., Martina,M., Koh,S., Ay,F. and Kohtz,J.D.
  TITLE     The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially
            Organizes Megabase Distant Genes in the Developing Forebrain
  JOURNAL   Mol Cell 71 (6), 956-972 (2018)
   PUBMED   30146317
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC019458.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019458.1, DV061045.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 8.16 cM"
     gene            1..768
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /note="LSM8 homolog, U6 small nuclear RNA associated"
                     /db_xref="GeneID:76522"
                     /db_xref="MGI:MGI:1923772"
     exon            1..129
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..389
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /note="U6 snRNA-associated Sm-like protein LSm8"
                     /codon_start=1
                     /product="LSM8 homolog, U6 small nuclear RNA associated"
                     /protein_id="NP_598700.1"
                     /db_xref="CCDS:CCDS39433.1"
                     /db_xref="GeneID:76522"
                     /db_xref="MGI:MGI:1923772"
                     /translation="MTSALENYINRTVAVITSDGRMIVGTLKGFDQTINLILDESHER
                     VFSSSQGVEQVVLGLYIVRGDNVAVIGEIDEETDSALDLGNIRAEPLNSVAH"
     exon            130..170
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /inference="alignment:Splign:2.1.0"
     exon            171..298
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /inference="alignment:Splign:2.1.0"
     exon            299..750
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /inference="alignment:Splign:2.1.0"
     regulatory      730..735
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /note="hexamer: AATAAA"
     polyA_site      750
                     /gene="Lsm8"
                     /gene_synonym="2010003I05Rik; Naa38"
                     /note="major polyA site"
ORIGIN      
        1 gccagcgggc gcgaagctgt ccgggtttct gtcgggcggt gttttgtctc ctcgttgccg
       61 agccctcgca gattcccggg acctccgggc ccagcagcat gacgtctgct ttggagaact
      121 acatcaaccg gactgtggct gttattactt ctgatggcag aatgattgtg ggaacactaa
      181 aaggttttga ccagaccatt aacttgattt tggatgaaag ccatgagcgg gtgttcagct
      241 cttcacaggg agtagaacaa gtggtgttgg ggttatacat tgtgaggggc gacaatgtag
      301 cagtcattgg ggaaatagat gaagagacgg attctgcact cgacttgggg aacatccgag
      361 cagagcctct gaactccgta gcacactgag acctcagtgt gtagtgagat gtgtgtaaat
      421 cctgtacaga agcgtctgtc ctgagagtga tgtttagggt ttttatgagt gtgtaattgt
      481 gcagtttgac ttcatgttgg tacactgtaa tatgtaattt aaatatttct acatttttta
      541 ttgggaaaca ttgcctaaat taataaatgt ggttggctgg tttatttttc taccaaatga
      601 tacaaaaatc taaggatcat ttgaaaactt agaaaatacc attacttttg gtaatttaat
      661 atttatggga aattggctgt aaagagaact tagactatta ttgtaactta tactaatgca
      721 aataatagta ataaaagaca catttctttt aaaaaaaaaa aaaaaaaa
//
