LOCUS       NM_001191004            3801 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus LSM6 homolog, U6 small nuclear RNA and mRNA
            degradation associated (Lsm6), transcript variant 1, mRNA.
ACCESSION   NM_001191004
VERSION     NM_001191004.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3801)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   2  (bases 1 to 3801)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 3801)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV648841.1, AK141884.1 and AC167022.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141884.1, AK161686.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                DV648841.1         1-54
            55-2362             AK141884.1         2-2309
            2363-3801           AC167022.4         99953-101391
FEATURES             Location/Qualifiers
     source          1..3801
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 37.22 cM"
     gene            1..3801
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="LSM6 homolog, U6 small nuclear RNA and mRNA
                     degradation associated"
                     /db_xref="GeneID:78651"
                     /db_xref="MGI:MGI:1925901"
     exon            1..105
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            106..204
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            205..309
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..458
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="LSM6 homolog, U6 small nuclear RNA associated"
                     /codon_start=1
                     /product="U6 snRNA-associated Sm-like protein LSm6"
                     /protein_id="NP_001177933.1"
                     /db_xref="CCDS:CCDS40396.1"
                     /db_xref="GeneID:78651"
                     /db_xref="MGI:MGI:1925901"
                     /translation="MSLRKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIA
                     LEQTEEYVNGQLKNKYGDAFIRGNNVLYISTQKRRM"
     exon            310..423
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            424..3801
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      607..612
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="hexamer: ATTACA"
     polyA_site      635
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="major polyA site"
     regulatory      681..686
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="hexamer: ACTAAA"
     polyA_site      705
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
     regulatory      1569..1574
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1588
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
     regulatory      2068..2073
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="hexamer: AACAAA"
     polyA_site      2108
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
     regulatory      2191..2196
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
                     /note="hexamer: AATACA"
     polyA_site      2220
                     /gene="Lsm6"
                     /gene_synonym="1500031N17Rik; 2410088K19Rik"
ORIGIN      
        1 cgctgattgg gtgagatggg aaagccgctg ccgggggcgg tttcggtttt cggcgcgcgc
       61 gtccgcggaa gcccggcctg tgagcgttct ggatccggct gcaagatgag cctggggccg
      121 tgacaggtga aatggtgatg agttacgcaa gctgcacaga taattaagta gcagagatta
      181 gaactcaggt ttcctgcctc ccaaggttgt taaacatgag cctgcggaag caaaccccta
      241 gcgacttctt aaagcagatc atcggacggc cagttgtggt gaaattaaat tctggcgtgg
      301 attatcgagg ggtcctggcc tgcctggatg gctacatgaa tatagccctg gaacagacag
      361 aggagtatgt aaatggacag ctgaagaata agtacggaga tgcgttcatc cgaggaaaca
      421 atgtgctgta cataagtaca cagaagaggc ggatgtgaag acaccaggag gcagtgctct
      481 tcagagatgg atagatgaag tggttttggt tctcttacca tcttagttgg cctgttttca
      541 tggtggctgg tgggggtttg tttgtttgtt tgtttaattg acattggaat aagatagagg
      601 tattgcatta cagatcgact cttaagtttt tcacatttat gtctcagtct ttatcatttc
      661 tgcctgtaca gaatgctaaa actaaaacag tttgtttctc caggattatt ttacctaaga
      721 ttcctgccct gtcattccat tggttgatta cgtattcagc tgactaagtg gtacatcccg
      781 gaacctgtga tcaagcattc tggaggcatc ctttgtctct ttctctactc accatccgta
      841 ccatttaaag caggtagata gaaagtcata tggtttcagc cttgggctat aaagggacaa
      901 gaggtcagaa aatcagctgt ttatttagtc acctagttag tggtggtatc tccacaaagg
      961 agtgcaactg tagagtcagg aattggaaag gtcagccacg tgaggtgaga cactgcctgg
     1021 aagcctcctg tgcagttaga ctcttcatgt taacttgctc cctgttgaga gtgttggtgc
     1081 aatggctggt tacgccagcc aggggaggag ctctactgtt cctgagaaac tggctgtggc
     1141 tgaggtggtg caagcccaga gtgcttagac tcagtttcca ggcactgagc ttcggctgcg
     1201 aaagtttctc ctgctttttg ctttagcaag tggccttggg gaaagggttg tattcttggc
     1261 cttcaggtca cgtgactccc gctgagcggg cttgtgctgt ctgtggactg tgtgtgggtg
     1321 ctttggttgc atggacgcta gggctttcct taccctcctt caatctaaac agatccctgt
     1381 ctcgggaggt cggacagttt tagagcaatt gcccggctgg aggaagtgga ggcagatgga
     1441 cagctaagga gggagggtgt gctttctgga gaggtgtata tatggcattt gtctaattta
     1501 aatagtaatc agaaacaatt aataactcag gaaagagagg agtaaggttt gatggtgtgc
     1561 acactgaaaa taaaacactt tatcctaagc ttcagtaatt catcacttcc tgacaggggc
     1621 ttgcaaaggc accagtgtgt aagtacaaat caccaatttg ctcttttata aatggcttct
     1681 ttaaaggaga aaatggatgt ctctcggagt ggagcacaca tgttctcatt tgttttttag
     1741 agtgtgtgag gccgccaggt tactgcatcc cttcattcat cccctcagct gccctgaaag
     1801 cagccctgct gttatctcca gcagtctgta acatcccggc tctgctcatt tcttccctga
     1861 cctcccctcc agcctgcagg tctttatttc cctcttgcca tttctagctt aatagcgcta
     1921 ctgcagaata ttgttttcat ccatggaacc gcttttaatc aagatggact ttgggaaatg
     1981 ctaccatttt tatggtaata accatattat gcatctggac cagcacatgt tgtcccctgt
     2041 gcataccttc ttgtgataga attctgaaac aaattgtaaa tggtaaaatt actttttttt
     2101 taactgtagt ctcctcgtgg tctgtgaatg gttttcagtt ggatggtagc aaagacaatt
     2161 gttgtagggt gaaaattttt cacttgagta aatacatttt ccgtgtccct atgcccccaa
     2221 ccacagttgc caccatcttt ctcttgggcc gtgacaaaac agaatgtcta gcaggaaaca
     2281 gaacttgtgc ttgctttcca gactatctgc cttcatattt tgttttggtc tgtgagctat
     2341 tccttggcta atcttgcaga ctgaatcaat tcttacttca aaagtgttta tcccaaacag
     2401 agctgtagac gagtacaaat acagatggcg gccatgtggt ctgaaccatg ttccccctca
     2461 gcctgcagac agggttcaca tcttgagcat catgtttgag gccatatgta atgcatgcga
     2521 ggagttccta atgatgtgac agatagtaac aaatgcttaa gggatttcct caaggttgga
     2581 aacagcagca tcgacttaag tgtgagccgc atcaccctgg aggctacagt cagcttcatt
     2641 agaaacaagc actgtgggaa aactgtcttt gatattcaca gtgcctcttg gatgacagca
     2701 ttccaggcca aggagccagt ctgtccctca gtgcagatta gcatacatgc ccgtctttac
     2761 agtgactttt ggtttaagag aaaatggtgt attggcttgt tcctcttgtg ggaagatctc
     2821 aaccttggag ttctcatagc caatctatgc ttgtcacgtt ttatttgttt ttcctgcccc
     2881 aaaacaaatt attggtgaaa gaagccaact gcagtttttc cctcacgacc ttcaagcggc
     2941 tgtgctccac agcagctacc tgttctaatc agctggcttc tgagagtaca cggctaggtg
     3001 tgctctgatc tgaataatgt ccagcagggg gttttatccc aggagctgct gccgtgtcta
     3061 ctgtagttgg ccaagcagtt atgagtgttt ccattgatca accatttgtg attccacaaa
     3121 gtcttgccta aaggacaggg tggacagtat gcacctctta tgtaataggg caagagacag
     3181 cctcaagtga tgcttgctta ttgtcttagt tgttactgct gtgaacagac accacgacca
     3241 aggcaactct tataaggacc acatttaact ggggccggct tacaggttca gagattcagt
     3301 tcattatcat caaggcagga acatggcagc atccaggcag gcatggtgca ggaggagctg
     3361 agagatctac atcttcatct gcaggccact aggagaagac tggcttccag gcagctagga
     3421 caagctaaag cccacgcctc agcgacacat gtccaaagaa gtgccactct ctgggccaaa
     3481 attcaagcca ccacacttac tttcttgaaa agttagagga gctaactagg gaggggagtt
     3541 ggaagaaatg atgttgatga tcagcgccca ctgaatggca gctgtggaca ggatctatgt
     3601 ggtaccctaa atgaataagt gagatactac cccctgtgca cgataggaag tcacttgcaa
     3661 gtctggctat ttataggaga aagtacctga cactgtcttt ttagatggga caggatttta
     3721 aaatagttca taaatgcatt tgatgtctca gctatgttca taccttaaaa tttcagataa
     3781 acttggaact ggaaaacctt g
//
