LOCUS       NM_026032               2360 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus LSM1 homolog, mRNA degradation associated (Lsm1),
            mRNA.
ACCESSION   NM_026032 XM_357867 XM_911934 XM_922221 XM_983898 XM_987686
VERSION     NM_026032.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2360)
  AUTHORS   Wei,W., Chen,Q., Liu,M., Sheng,Y., OuYang,Q., Feng,W., Yang,X.,
            Ding,L., Su,S., Zhang,J., Fang,L., Vidal-Puig,A., Wang,H.Y. and
            Chen,S.
  TITLE     TRIM24 is an insulin-responsive regulator of P-bodies
  JOURNAL   Nat Commun 13 (1), 3972 (2022)
   PUBMED   35803934
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2360)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 2360)
  AUTHORS   Yang,G., Smibert,C.A., Kaplan,D.R. and Miller,F.D.
  TITLE     An eIF4E1/4E-T complex determines the genesis of neurons from
            precursors by translationally repressing a proneurogenic
            transcription program
  JOURNAL   Neuron 84 (4), 723-739 (2014)
   PUBMED   25456498
REFERENCE   5  (bases 1 to 2360)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 2360)
  AUTHORS   Hoefig,K.P., Rath,N., Heinz,G.A., Wolf,C., Dameris,J., Schepers,A.,
            Kremmer,E., Ansel,K.M. and Heissmeyer,V.
  TITLE     Eri1 degrades the stem-loop of oligouridylated histone mRNAs to
            induce replication-dependent decay
  JOURNAL   Nat Struct Mol Biol 20 (1), 73-81 (2013)
   PUBMED   23202588
REFERENCE   7  (bases 1 to 2360)
  AUTHORS   Pessa,H.K., Will,C.L., Meng,X., Schneider,C., Watkins,N.J.,
            Perala,N., Nymark,M., Turunen,J.J., Luhrmann,R. and Frilander,M.J.
  TITLE     Minor spliceosome components are predominantly localized in the
            nucleus
  JOURNAL   Proc Natl Acad Sci U S A 105 (25), 8655-8660 (2008)
   PUBMED   18559850
REFERENCE   8  (bases 1 to 2360)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 2360)
  AUTHORS   Kerr,S.M., Vambrie,S., McKay,S.J. and Cooke,H.J.
  TITLE     Analysis of cDNA sequences from mouse testis
  JOURNAL   Mamm Genome 5 (9), 557-565 (1994)
   PUBMED   8000140
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK041290.1.
            
            On or before Jul 24, 2006 this sequence version replaced
            XM_357867.4, XM_987686.1, XM_911934.2, XM_922221.2, XM_983898.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK041290.1, BC021460.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 14.17 cM"
     gene            1..2360
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /note="LSM1 homolog, mRNA degradation associated"
                     /db_xref="GeneID:67207"
                     /db_xref="MGI:MGI:1914457"
     exon            1..127
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..483
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /note="LSM1 homolog, U6 small nuclear RNA associated"
                     /codon_start=1
                     /product="U6 snRNA-associated Sm-like protein LSm1"
                     /protein_id="NP_080308.1"
                     /db_xref="CCDS:CCDS22202.1"
                     /db_xref="GeneID:67207"
                     /db_xref="MGI:MGI:1914457"
                     /translation="MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLH
                     QTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVQ
                     QQTRLEAEKLKVQTLKDRGLSIPRADTLDEY"
     exon            128..196
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /inference="alignment:Splign:2.1.0"
     exon            197..312
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /inference="alignment:Splign:2.1.0"
     exon            313..2360
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /inference="alignment:Splign:2.1.0"
     regulatory      891..896
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /note="hexamer: AATAAA"
     polyA_site      922
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /note="major polyA site"
     regulatory      1636..1641
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
                     /note="hexamer: AAGAAA"
     polyA_site      1656
                     /gene="Lsm1"
                     /gene_synonym="2810025O06Rik; CASM"
ORIGIN      
        1 ggccggttcc cgtccgcgtc ccgccgacgg gcgactggac gccctcgcgg ccgtccggtg
       61 cagccttgcg agagctcaaa catgaactat atgcccggca ccgccagcct catcgaggac
      121 atcgacaaaa agcacttggt cctacttcga gatggaagaa cacttatagg ttttttaaga
      181 agcattgatc aatttgctaa cttagtgctc catcagactg tggagcgaat tcatgtgggc
      241 aaaaagtacg gtgatattcc tcgagggatt ttcgtggtca gaggagagaa tgtggtccta
      301 ctaggagaaa tagacctgga gaaggagagt gacacgcccc ttcagcaagt gtctattgaa
      361 gagatcctag aggaacagag ggtgcaacag cagaccagac tggaggcaga gaagctgaag
      421 gtccagaccc ttaaagatcg gggcctttcc attcctcgcg cagacactct ggacgagtac
      481 tgagtccttg ctcagagact gctctagaga gcaggtgctg tcacctggtc acctcacaca
      541 ttgaccagag tatcacgctg aaaagtgatc tcattctttc atggatgcca acatgaagaa
      601 atcatgggat tttggttttt ttaaacaaaa tcattgtata ttagttttgc ttttcttctt
      661 cagtctcagc acatagtcct ggctgaccta gagctcactg tgtaaaccag ggtgaccttt
      721 agcttgtggg actgcaggtg gcctccacct ccaccagccc agctttactg tctaaagaaa
      781 cagtggcgtg acctccctca cacaagtcac tgtggagcca agaactatgt ctttatattg
      841 cttatctcag agtttacatt tcttttttaa aaatatttca tttacttgta aataaaaaat
      901 gattctcaga actgtcacaa aatggagttt ctggtggaga gtcaaaattc cctactgcaa
      961 cataaggctg tatacatcct aatgtataca ctaggatgcc tactgtggat atagctggct
     1021 cctcaggagg acatttcata ctctgctgct tcctagttcc cattttcatg tttgtacttg
     1081 gcagaagttt taagcttgag aagggagttt tcaaggaact ggttacaaca gaatcctcag
     1141 gtttagaaaa cttgagccct gatttaccca cagtttttcc aaactataag aatatgcttt
     1201 gctctcaatc ttacattaac ttatccagat tttcaactcc ttttgatcat cttttgctta
     1261 gattatcatc tatacaagaa caacaaccct ccctacacac acacacacac aaaagccctc
     1321 aaatggtgct tagtaacaat tgattcatga tgacagcacg ttttgttggc ttgattgttg
     1381 gagagtaata attgcgtagg aagtctgaca gatgacactt tagaagcagt gtgtttcagt
     1441 acacagagtg agcaatgagg caacagcata gaaattggct tattggcaca ctgaaatgtt
     1501 tctcagtaat ttatctcgga tatatcattt tttataatct tttgaacagt agtactcttc
     1561 tctttcctaa gaggtttgtg gactttttca tactgcaata tgaaatacac ttttttatgt
     1621 tctcaggtgt ttaaaaagaa aaaacctacc ctggaagcca tttggcacgt gaattcttta
     1681 ttgttgagtt gattttacag tagatacttt ttgaagttat tgtccttgga ttgaggatgt
     1741 ggctcagtaa gtagcagaat gcttgcttag gatatgcaag gtccacatgt cacatgccta
     1801 agtacagtga catcctagtt cagggacagc agagtgactg gttaattgag ctctgcgtag
     1861 gtcacttagt tatttcagca tcagtcagac aattccagtg tagcagcaga tatgagttac
     1921 aaagggacat tcctgccctt gacacctacg ttctttgcaa ggttcagctg tgtgaggttt
     1981 ccagtccagg tcatgcagca gcctggaagt ggtcttaaaa gttaacactg tcgggcctgc
     2041 ttcccctctc tccccttggg ttctcagctg agggcctgct tctgctgccc ttccctgtgt
     2101 tcgtactgag aggcagtgct ctgaccaaac tggccgtcgc aggagcaaat ccagttcata
     2161 ctgaaagttc ctaccagctg gggggattcg attccccaga gccctgcgtg tagccatgtg
     2221 cattctgaaa ctactgcgca tggctgcttc aggctctttt aatgtctccc gaggcccttc
     2281 atattcaatt tcatgctctc tgcttattaa accacaatat cctctcccct ctaccctgaa
     2341 tagaatacaa aagaaaatgt
//
