LOCUS       NM_172879               2951 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus leucine rich repeats and death domain containing 1
            (Lrrd1), mRNA.
ACCESSION   NM_172879
VERSION     NM_172879.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2951)
  AUTHORS   Suzuki,A., Yabuta,N., Shimada,K., Mashiko,D., Tokuhiro,K.,
            Oyama,Y., Miyata,H., Garcia,T.X., Matzuk,M.M. and Ikawa,M.
  TITLE     Individual disruption of 12 testis-enriched genes via the
            CRISPR/Cas9 system does not affect the fertility of male mice
  JOURNAL   J Reprod Immunol 163, 104252 (2024)
   PUBMED   38697008
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022236.4 and AC027653.3.
            
            On Nov 27, 2007 this sequence version replaced NM_172879.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029981.1, BC141026.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               AC022236.4         2174-2447           c
            275-2238            AC027653.3         107242-109205       c
            2239-2437           AC027653.3         100010-100208       c
            2438-2599           AC027653.3         94846-95007         c
            2600-2717           AC027653.3         93055-93172         c
            2718-2951           AC027653.3         92241-92474         c
FEATURES             Location/Qualifiers
     source          1..2951
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 2.26 cM"
     gene            1..2951
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /note="leucine rich repeats and death domain containing 1"
                     /db_xref="GeneID:242838"
                     /db_xref="MGI:MGI:3045299"
     exon            1..274
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            275..2238
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             340..2901
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /codon_start=1
                     /product="leucine-rich repeat and death domain-containing
                     protein 1"
                     /protein_id="NP_766467.2"
                     /db_xref="CCDS:CCDS19068.1"
                     /db_xref="GeneID:242838"
                     /db_xref="MGI:MGI:3045299"
                     /translation="MSEDGSNVEPGGFPRFESLEEPGSEISDLLDEASPYSKSKDSNQ
                     IYEANPSKDTEQSAASFTSQLDRNEEKNTGIPFSETNIADIIPLSIEESLQSSGSSET
                     KMAEDYYPVKFPTGRKFRGRIFNGNQKGLDMKSDNFTVNLDAKGLQEFPVDIVKVKYV
                     KYLYLDKNQIKNFQGIDPGDLLGLEILSLQENGLSSIPLEIQLFHNLKILNASYNEIS
                     QIPKELLQLENMRQLLLNSNHIDTLPSGLEHLRYLETLSLGKNMLTYIPDSLSSLKNL
                     RILNLEYNQLTIFSKSLCFLPKLNSLNLTGNMIGSLPKEVRELKNLESLLMDHNKLTF
                     LAVEIFQLPKIKELHLADNKLEAISPKIENFKELRLLNLDKNLLQSIPKKISHCVNLE
                     SLSLSDNNIEELPKKIRKLKNLRQLHVNRNKMITMTEEISHLSNIHILEFSGNQITHV
                     PIEIKNCRKITRVELNYNNIMYFPVGLCALQSLDYLSFNGNYISEIPVDMSFSKQLLH
                     LELNRNKLTVFSKHLCSLTNLEYLDLAKNQIMTIPSCISAMVSLHVLILSDNKFESFP
                     KELCSLKNLRVLDISENKLQKIPLEISKLKRIQKLNLSNNIFTNFPVELCQLQTLEEL
                     NISQTSGKKLTRLPEEVSHMTQLKILNISNNAIKDIPKNIGELRSLVSFYASNNQISS
                     LPSSFLSLEVLQSLDLRGNNMTALPSGIYKLSSLKEINFDDNPLMRPPMEICKGKEMH
                     MITCYLQRADERDEKILEKIFNIVANSITETNFEFLQQKLNMASSANNMPVRPTTPLN
                     ERIYQALIKWKAEKDVQFTATALRDKLFRALNMIGAYDIMDKITALNLYTSAIKL"
     exon            2239..2437
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2438..2599
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2600..2717
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2718..2951
                     /gene="Lrrd1"
                     /gene_synonym="4932412H11Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttcggagag ccacagagag gctccacggg actgatctaa ggactgctaa gcccaggcta
       61 ggttcttttc ccgcctccgc atcccgcatc tcgggcatct cgcaacaact gtagaggtgc
      121 gcatccccct cccttcatgc tcccagccca ccgcttctag catttgcatt ctgtcccagg
      181 ctgctttagc ctccgctcag cgttcttctc cctacaccgg tcgaagcatt gaaaaagtct
      241 tgtagttacc tggatggcca catcgttcag ataggttcaa aggaaaaaac acaaaagatt
      301 aaagttatag tcttagttcg tgcaagagtt tccagtaaga tgtctgaaga tgggagtaat
      361 gtggagcctg gaggatttcc tagatttgag tcactggagg agcctggatc tgaaatatca
      421 gatctcttgg atgaagcttc tccttactca aaaagtaaag attccaacca gatttatgaa
      481 gcaaatcctt caaaggacac agaacagtca gcagcttcct tcacaagcca gcttgataga
      541 aacgaagaga aaaatacagg aattccattt tcagaaacta acatagcaga tatcatccca
      601 ctgtcaatag aagaaagtct gcagagctct gggtcatcag agactaagat ggctgaagat
      661 tattacccag tcaaatttcc aactgggagg aaatttagag gacgaatctt taatggaaat
      721 cagaaaggat tggacatgaa gtctgataac tttacagtta atcttgatgc caagggttta
      781 caagaattcc ctgtagacat tgtcaaagtc aaatatgtaa aatatctata tttagataag
      841 aatcaaataa aaaatttcca agggatagac ccaggggatt tgctaggact tgaaattctg
      901 tccttgcaag aaaatggatt gtcatcaatt cccttggaaa ttcagttgtt tcacaactta
      961 aagatactaa atgccagtta caatgagata tcacagatac ccaaagaact actacaactt
     1021 gagaatatga gacaactcct cttaaatagt aatcatattg acactttacc ttctggctta
     1081 gaacatctta gatatttgga aactttaagt ttgggtaaaa atatgttaac atatatacca
     1141 gattctttgt ctagtttgaa aaatttgaga attctcaatc tggaatataa ccaattaaca
     1201 atattttcaa aatcattatg cttccttcca aaattaaatt ccctaaacct tactggaaac
     1261 atgataggca gtttgccaaa agaagtgagg gaactgaaaa atttagaaag ccttctaatg
     1321 gatcacaata aacttacttt tttggcagta gaaatatttc aattgcccaa aataaaagaa
     1381 cttcatctag ctgacaataa actggaagcc atttcaccca aaattgagaa tttcaaagaa
     1441 ctcaggctgc ttaaccttga taaaaattta ttgcaaagca taccaaaaaa aatttcccac
     1501 tgcgtaaatt tggaatctct tagtcttagt gataataata tagaagaact tcctaagaaa
     1561 atccgtaagc ttaaaaattt gagacaactc catgtaaaca gaaataaaat gataacaatg
     1621 actgaagaaa tctcacatct tagtaatata cacatcctgg agttttcagg caatcaaatc
     1681 acacatgttc ctattgaaat aaaaaactgc agaaaaataa caagagttga actgaattat
     1741 aacaatataa tgtatttccc agtggggttg tgtgctttgc aatcacttga ctacttgagt
     1801 tttaatggaa attatatttc agaaatccct gtggacatgt cgttcagtaa gcagctgctt
     1861 catttagagt tgaatagaaa caaactcacc gtattttcaa aacatttatg ttctctcact
     1921 aatcttgaat acctggatct tgctaaaaac caaataatga caattccatc ctgtatctct
     1981 gctatggtat cactccatgt tctcattcta tctgataata agttcgagag tttcccgaag
     2041 gaactgtgtt ctttaaaaaa cttgcgagtg cttgatattt cagaaaataa attacagaaa
     2101 atacctttag aaatatccaa actgaaaagg atccagaagt taaacttgtc aaacaatatt
     2161 ttcacaaatt ttcctgttga actgtgccaa cttcaaactc ttgaggagct gaatataagt
     2221 cagacaagtg ggaaaaagtt aacaagactt ccagaagagg tgtctcatat gactcaactc
     2281 aaaatactca acatctcaaa caatgccatc aaagatattc caaaaaatat aggggagctg
     2341 agaagtctgg ttagttttta tgcgagcaac aatcaaataa gttctcttcc atcatccttt
     2401 ctgtctttag aagttctaca gagcctagat ctcagaggaa acaatatgac agctttgccc
     2461 agtggtatct acaaactttc atctctgaaa gagataaatt ttgatgacaa tcctttgatg
     2521 agaccgccaa tggaaatctg taaaggaaaa gagatgcata tgatcacatg ctatctccaa
     2581 agagcggatg aaagagatga gaaaatctta gagaagatat tcaacatagt tgccaacagt
     2641 atcactgaaa caaattttga atttttgcaa caaaaactaa acatggcaag ctcagcaaac
     2701 aacatgcctg taaggcccac tactccatta aatgaaagaa tctaccaggc actcattaag
     2761 tggaaagcag agaaggatgt acaattcaca gctactgccc taagagacaa actttttcgg
     2821 gcactaaata tgataggtgc ctatgatata atggacaaga tcacagcgct gaacctttat
     2881 acaagtgcca tcaaactcta gccggtggat ctgaaatagt agttaaacct taccttgcac
     2941 ttacagaact g
//
