LOCUS       NM_001142728            4739 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus leucine rich repeat containing 9 (Lrrc9), transcript
            variant 1, mRNA.
ACCESSION   NM_001142728
VERSION     NM_001142728.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4739)
  AUTHORS   Skarnes,W.C., Rosen,B., West,A.P., Koutsourakis,M., Bushell,W.,
            Iyer,V., Mujica,A.O., Thomas,M., Harrow,J., Cox,T., Jackson,D.,
            Severin,J., Biggs,P., Fu,J., Nefedov,M., de Jong,P.J., Stewart,A.F.
            and Bradley,A.
  TITLE     A conditional knockout resource for the genome-wide study of mouse
            gene function
  JOURNAL   Nature 474 (7351), 337-342 (2011)
   PUBMED   21677750
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK029802.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029802.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3241              AK029802.1         2-3242
            3242-4739           AK029802.1         3244-4741
FEATURES             Location/Qualifiers
     source          1..4739
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 30.2 cM"
     gene            1..4739
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /note="leucine rich repeat containing 9"
                     /db_xref="GeneID:78257"
                     /db_xref="MGI:MGI:1925507"
     exon            1..303
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            304..384
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             337..4707
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     leucine-rich repeat-containing protein 9"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 9 isoform
                     1"
                     /protein_id="NP_001136200.1"
                     /db_xref="CCDS:CCDS49085.1"
                     /db_xref="GeneID:78257"
                     /db_xref="MGI:MGI:1925507"
                     /translation="MIESENLNRGEIIKELCLCNGLTYEIVGQEGSDTSKLEMFFSGY
                     PRIVGLSLFHNLSSLTIVAQDIREISGLETCLQLKELWIAECCIEKIEGLQGCRNLEK
                     LYLYYNKISKIENLEKLIKLEVLWLNHNMIKNIEGLQTLKNLKDLNLAGNLVSSIGRC
                     LDPNEQLEKLNLSGNQITSFKDLTNLTKLTRLKDLCLNDPQYKSNPVCQLCNYSTHVL
                     YHLPSLQRLDTFDVSAKQIKELADSTAMKKIMYYNMRIKTVQRHLNEELEKLNDRKCK
                     LQKLPEERIKLFNFAKKTLERELAELKISSKGQSDTTPEAEKPRNSEVVTQESVLQQK
                     ILTKLSALDDRVTFWNKKLHEIEAIYRTEVKQKKKTHGLLTPFLLTELETVGNIHFEE
                     GTQADDWFNSCCELILSRFCTWDFRAYGITGVKVKRVIKVNNRILRLKFEEKFQKCLD
                     LEDTQDPDYRKMLECLFYVFDPEVTVKKKHLLQILERGFKDSDTSKPSLKKEAVTLVN
                     SLSMCECPRIEFLQQKYKEEKKGPSESELYRHGTILIAKVFLGQSIQARDQEPINKAN
                     YPMVNSVFVPQRHVLRQRTCDCGYRQYKWFVFDHDLVLPEYIVEFEYTTVVKVHSLFS
                     TSNNVILEEGKKYSEGLVFSQDLKFDDEVLKMEPRIKPRPKLISLDEKTIISLAKTNI
                     YSHIVNLNLHGNSLSKLRDLAKLTGLRKLNISFNEFTCLDDVYHLYNLEYLDASHNHV
                     ITLEGFRGLMKLKHLDLSWNQLKKTGEEINVLCKHTTSLLTLDIQHNPWQKPATLRLS
                     VIGRLKTLTHLDGLVISEEETRAALKFISGTKITQLTLLQHSSSKEERPRMLSTWPSA
                     KILTQISKLGPHFHLTGNWYSKITALNLDGQHLFEITNLEKLENLKWASFSNNNLSKM
                     EGLESCVNLEELTLDGNCISKIEGITRLTKLSRLSMNNNLLTGLEKHTFDNLLHLHSL
                     SLENNRITSLSALQKTFTLIELYISNNYIAVNQEIYNLKGLCNLVILDMYGNIIIWNQ
                     ENYRFFVIFHLPELKALDGVSIETSETETAKDLFGGRLTSDMIAERQGHSNFIQMQEL
                     NWTSSAIRTVDLIPVDHFRNVSNVNLQNNNLTSFSGLIYLPNVKVLCLNYNHIESIMP
                     RLKPQTHLSSRQLLYQKVPSSGYGQQGTSKLNRDSVGSENLPPIMQSLEVLHLGYNGI
                     CNLVQLQLNRLRNLKFLFLQGNEISQVEGLDNLIVLQELVVDHNRIRAFNDTAFSKPS
                     SLLMLHLEENRLRELSKLQSLVKLEKLFLGYNKIQDITELEKLDVIPSLRELTVYGNP
                     ICRKMVHRHVLIFRLPNLQMLDGIPINSDDRAKAEFHFSELQAKKSSIIQNNLPTSKS
                     SLPSHLQTPLPCKFVPVTNSTDGGSFCHVKASPIKITNVLLPAGFSRFLGPDFTLTPE
                     VEGIFTKSFRENEKTNKQQQ"
     exon            385..603
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            604..744
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            745..808
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            809..879
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1062
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1218
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1400
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1532
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1709
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1824
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1825..1957
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2080
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..2184
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2397
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2398..2517
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2518..2709
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2710..2835
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2836..2970
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2971..3148
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3149..3369
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3370..3492
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3493..3623
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3624..3732
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3733..3872
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3873..4009
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4010..4227
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4228..4296
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4297..4437
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4438..4509
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4510..4739
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4703..4708
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /note="hexamer: AATAAA"
     regulatory      4710..4715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /note="hexamer: AACAAA"
     polyA_site      4729
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /note="major polyA site"
     polyA_site      4736
                     /gene="Lrrc9"
                     /gene_synonym="4921529O18Rik; 4930432K16Rik"
                     /note="major polyA site"
ORIGIN      
        1 gggggctcac cgggctcttg gtggcctcag ctgcgcagca gctgggaccg aggccatcag
       61 cggcggaagg ggaaccgtct tatgacctca ctgctccacg ccatgctggg gatcaagacc
      121 agttagtact gctgacttcg aggctccagg tgtcaaaaac tttaactgtg aaaatgccag
      181 gaccaggtcc ccaccgccta gcccacaaac tgtcactgtc ctcggaagga aacaaagtga
      241 acacccaaga ctaagaacta ggcagcgacc ggctgccacc gctccgcggg agtcttaaca
      301 aagatatatt agtgtgacca ttgtttttaa tggaagatga ttgaaagtga aaacctaaat
      361 cgaggtgaaa tcattaaaga actgtgtctg tgcaatggct taacttatga gatcgttgga
      421 caggaaggat cagatacttc aaaactggag atgtttttct cagggtatcc ccgaatagtt
      481 ggattatcat tgtttcataa tttatcaagt cttacaattg ttgctcaaga tataagggaa
      541 atttcagggt tggagacttg cttacagctt aaagaacttt ggattgctga atgctgcata
      601 gagaaaattg aaggccttca aggatgtaga aatttggaaa aattatattt atattacaat
      661 aaaatttcca aaatagaaaa tttagagaag ttaataaaat tggaagttct gtggctgaac
      721 cacaatatga taaaaaatat tgagggcttg cagactttga agaatctaaa agacctcaac
      781 cttgcaggaa acttagtcag cagcattggt cgatgtcttg atcccaatga acaactggaa
      841 aaactaaacc tttctggaaa tcaaattact tccttcaagg accttactaa cttgaccaag
      901 ctcactcgct taaaggactt gtgtctgaac gaccctcagt ataagtccaa ccccgtgtgt
      961 cagctgtgta actattccac ccacgtgctc taccacttgc cgtctctcca acgactcgac
     1021 acgtttgacg tatcagcaaa gcaaatcaag gagctggcgg attccacagc aatgaaaaaa
     1081 ataatgtatt ataacatgcg aataaaaact gttcagagac atctgaatga agaacttgaa
     1141 aaactaaatg acagaaaatg caagttacag aagctacccg aagaacggat aaaattattc
     1201 aactttgcaa agaaaacgtt agaacgggaa ctggctgaac tcaagatctc tagcaaaggg
     1261 cagagcgata caacgccgga ggccgagaaa ccccggaata gtgaggttgt cacacaggaa
     1321 tcagttctgc agcagaagat actgaccaag ctgagcgctc tggatgacag agttacattc
     1381 tggaacaaga aactgcatga gattgaagcg atttatcgga ctgaagtaaa acagaagaag
     1441 aagactcacg gcttactgac cccgtttctg ctaactgagc tggagactgt gggcaatatc
     1501 cattttgaag aaggcactca ggctgatgac tggtttaact cctgctgtga actaatcctg
     1561 tcgcgtttct gcacctggga cttcagagcg tacggcatca cgggggtgaa ggtgaagcgg
     1621 gtcattaaag tcaacaaccg tattctgagg ctgaagtttg aagagaaatt ccaaaagtgt
     1681 ttggatcttg aagacacaca agatccggat taccggaaga tgctggagtg ccttttctac
     1741 gtctttgatc ccgaagtgac tgtaaagaag aagcatctgc tacagatact tgaaagggga
     1801 ttcaaagaca gcgacacaag caagccctct ctcaaaaagg aagccgtcac tcttgtgaac
     1861 agcctcagta tgtgtgagtg tccccggata gagttcctcc agcagaaata caaggaggag
     1921 aagaaaggcc cctcagagag tgaactctac agacatggca ccatcctcat tgcgaaggtt
     1981 tttcttggcc agagtattca ggctcgtgac caggagccca tcaataaagc caactatccc
     2041 atggttaact cggtgtttgt tcctcagaga catgtgctaa gacaaagaac ttgcgactgt
     2101 ggctaccggc agtacaaatg gtttgtcttc gaccatgacc tcgttttgcc agagtacatc
     2161 gttgaatttg agtacactac agtggtcaaa gttcactctt tattttctac atcaaacaac
     2221 gttattctag aggaaggcaa aaagtattct gaaggattag tattctcaca ggatttgaaa
     2281 tttgatgatg aagttctgaa gatggaaccc aggattaagc cccgcccaaa actcattagt
     2341 ttggatgaga agactataat ttcccttgct aagactaata tttacagcca tattgtgaat
     2401 ctgaatctac acgggaatag cttgagtaaa ctgagagatc ttgccaagct aactgggctt
     2461 cggaagctga acattagctt caatgagttt acttgcttag atgatgtgta ccacttgtac
     2521 aaccttgagt atttggacgc cagccataac catgtgataa ccctagaggg attcagaggc
     2581 ctgatgaaac tgaagcattt ggacttgagc tggaaccagc tgaagaagac tggggaagag
     2641 atcaatgtgc tgtgcaaaca caccaccagc cttctcaccc ttgacattca gcacaacccc
     2701 tggcagaagc cagccacatt gaggctgagt gttattggca gactaaagac tcttacacac
     2761 ttagacggcc tcgtcatttc tgaagaagaa accagagcag ctctgaaatt cattagtgga
     2821 acgaagatta ctcagctaac tctcttacag cattccagtt ctaaagagga aaggcctcgg
     2881 atgctcagta catggccctc tgccaaaatc ctgacccaga tttccaagct gggaccccac
     2941 tttcacctga ccgggaactg gtactcaaag ataactgcct taaatttaga tggacaacat
     3001 ctctttgaaa tcacaaatct agaaaaattg gagaatttga aatgggcatc gttcagcaat
     3061 aataacctct ccaaaatgga aggccttgag tcctgtgtca acctggagga gctcacatta
     3121 gacggcaact gcatctcaaa gatagaaggc atcaccaggc tgacaaagtt aagccgcctc
     3181 agcatgaaca acaaccttct cacgggcctg gagaagcaca cgtttgataa cctgcttcac
     3241 cttcactccc tctctctgga gaacaacagg atcacatctc tgagcgcgtt acagaagacc
     3301 ttcactctga tcgagttgta cataagcaac aactacatag ctgtgaacca ggagatctac
     3361 aacttaaagg gtttatgcaa cttggtcatt ctagacatgt atggaaacat tattatatgg
     3421 aaccaagaaa actaccggtt ctttgtaata tttcatcttc cagaactgaa agccttggat
     3481 ggagtctcaa ttgagacatc agagacagag actgcaaaag atttgtttgg tggacggctt
     3541 acctctgaca tgattgccga acgacaagga cactcaaact ttatccaaat gcaagagcta
     3601 aactggactt catcagccat caggaccgtg gatctgattc ctgtcgacca cttcaggaat
     3661 gtgagcaacg tgaatctcca gaacaacaac ctcacctcgt tcagcggcct catctacctg
     3721 cccaacgtga aggtcttatg cctcaactac aatcacattg aatcaattat gcctagacta
     3781 aagcctcaga cccacttaag cagcagacag ctgctctacc agaaagtgcc ctcaagtggc
     3841 tacggacagc aaggaacctc aaaactaaat agagattcag taggcagtga gaacttgcct
     3901 ccaataatgc aaagtttaga ggttctgcat ttgggataca atggaatttg taacttagtc
     3961 cagctacaac ttaacagact gagaaactta aagttcctct ttctccaggg aaatgagatc
     4021 agtcaggtgg aagggctgga caacctgatc gtcctccagg agctggtcgt cgaccataac
     4081 cgcatccggg cctttaatga caccgcgttt tccaagccaa gttccctgct gatgcttcat
     4141 ctagaggaaa acaggctgcg agaactaagc aaactgcagt ctttggtcaa actggagaaa
     4201 ctcttcctag gatataacaa aatccaggat atcacagaac tggaaaaact tgatgttatt
     4261 ccttctctca gagagcttac tgtctatggc aatccaattt gtaggaaaat ggttcatcga
     4321 catgtgctca tattccgcct gcctaattta cagatgttgg atggaattcc tataaattct
     4381 gatgataggg caaaagctga gtttcatttc tctgaactac aagcaaaaaa aagttcgata
     4441 atccagaata atctccctac ttccaagtcc tcacttccat cacacctgca aactcctttg
     4501 ccatgtaagt tcgttcctgt taccaactct acggatggtg ggtcattctg ccacgttaaa
     4561 gcctctccca ttaaaataac aaatgttctt ctgcctgctg gatttagccg tttcttggga
     4621 cctgacttca ccttaactcc tgaagttgaa ggtattttta caaagagttt cagagagaat
     4681 gaaaaaacga acaagcagca gcaataaaaa acaaagggaa aaaccctcat ttaaaagag
//
