LOCUS       NM_198860               4601 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus leucine rich repeat containing 75B (Lrrc75b), mRNA.
ACCESSION   NM_198860 XM_112504
VERSION     NM_198860.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4601)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4601)
  AUTHORS   Zhong,Y., Zou,L., Wang,Z., Pan,Y., Dai,Z., Liu,X., Cui,L. and
            Zuo,C.
  TITLE     Lrrc75b is a novel negative regulator of C2C12 myogenic
            differentiation
  JOURNAL   Int J Mol Med 38 (5), 1411-1418 (2016)
   PUBMED   27633041
  REMARK    GeneRIF: Data show that leucine rich repeat containing 75B
            (Lrrc75b) is a suppressor of C2C12 myoblast myogenic
            differentiation.
REFERENCE   3  (bases 1 to 4601)
  AUTHORS   Endoh-Yamagami,S., Karkar,K.M., May,S.R., Cobos,I., Thwin,M.T.,
            Long,J.E., Ashique,A.M., Zarbalis,K., Rubenstein,J.L. and
            Peterson,A.S.
  TITLE     A mutation in the pericentrin gene causes abnormal interneuron
            migration to the olfactory bulb in mice
  JOURNAL   Dev Biol 340 (1), 41-53 (2010)
   PUBMED   20096683
REFERENCE   4  (bases 1 to 4601)
  AUTHORS   Thuret,S., Bhatt,L., O'Leary,D.D. and Simon,H.H.
  TITLE     Identification and developmental analysis of genes expressed by
            dopaminergic neurons of the substantia nigra pars compacta
  JOURNAL   Mol Cell Neurosci 25 (3), 394-405 (2004)
   PUBMED   15033168
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC056492.1 and AK132309.1.
            
            On Jun 17, 2008 this sequence version replaced NM_198860.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055322.1, SRR1660819.246225.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2303              BC056492.1         1-2303
            2304-4601           AK132309.1         2027-4324
FEATURES             Location/Qualifiers
     source          1..4601
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 38.55 cM"
     gene            1..4601
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /note="leucine rich repeat containing 75B"
                     /db_xref="GeneID:192734"
                     /db_xref="MGI:MGI:2143657"
     exon            1..375
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1131
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /note="leucine-rich repeat-containing protein C22orf36
                     homolog; leucine-rich repeat-containing protein FAM211B;
                     family with sequence similarity 211, member B"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 75B"
                     /protein_id="NP_942560.1"
                     /db_xref="CCDS:CCDS35937.1"
                     /db_xref="GeneID:192734"
                     /db_xref="MGI:MGI:2143657"
                     /translation="MGARLGRRARADAPAAPSAGPAPYERRVRWLREIQSTLRERRPE
                     RARQLLRLLRQDLGLEGNLLTDILHRNVTFLNLVDPISHDLLVNLARDLQCPKKDHEL
                     WKSSDKICRQLIYHLTPHSKRKHHRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQ
                     HISRYLDTRGVELVVLDLSFTELSDELLHLLLPSLWALPRLTQLLLNGNRLTRAAARE
                     LTEAIKDTAKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEPG
                     GGMAETTAAVSTWGSAATEAGPEPQGCCAR"
     exon            376..504
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /inference="alignment:Splign:2.1.0"
     exon            505..605
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /inference="alignment:Splign:2.1.0"
     exon            606..4601
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4574..4579
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc75b"
                     /gene_synonym="Fam211b"
                     /note="putative"
ORIGIN      
        1 gggaagagct ccaacaccag gtcgtacgcg ggcggggccc tcgacaacga aacctctgcc
       61 aaagaggagt gaccctgggc tccacgctgg cggccagtgc ttgggcgcgc agccgtagac
      121 ccggcattgc ccatcccgcg catcccgggc ggggcgcggc gcggctaacc cgcctccctt
      181 ccatcctccc ggcgcccgcc cgcggcggcc atgggggcgc ggctggggcg gcgggcgaga
      241 gcagatgccc ctgcggcgcc gagtgcgggg cccgcgccct acgagcgccg ggtgcgctgg
      301 ctgcgagaga tccagtccac gcttcgggag cggcggccgg agcgcgctcg gcagctgctg
      361 cgcctcctgc gccaggacct gggccttgaa gggaacctcc tcactgacat cctccacagg
      421 aatgtgactt tccttaactt ggtggacccc atctcccatg acctgctggt gaacctggcc
      481 cgggacctgc agtgccccaa gaaggaccat gagctctgga agtcctcgga caagatctgt
      541 cggcagctca tctaccacct cactccgcac tccaagcgaa aacaccacag gaaaacccag
      601 agcagcctca agagcagcct ccagaagact ctgctggtag gggagactgt ggatctttct
      661 ggcatcccgc tctcggcccg ggatgtgcag cacatatcac gctacctgga cactcgtggt
      721 gtagagctgg tggtcctgga cctgagcttc acggagctga gcgatgagct gctgcatctg
      781 ctgctgccca gcctctgggc gctgccccgc ctcacccagc tgctgctcaa tggcaatcgg
      841 ctgaccagag ctgctgcccg ggaactcacc gaggctatca aggacactgc caagttcccc
      901 gtgttggcct gggtggacct ggggaacaat gtggatgtgt cttcacttcc ccaacccttg
      961 ctggttggcc tccggaggcg actgagccag catacctcgc tccccactat ctatgagggc
     1021 ctggacctcg agcctggggg cggcatggct gagaccactg ctgctgtctc cacctggggc
     1081 tctgccgcca ctgaggcagg accagaacct cagggttgtt gtgccaggtg acttcctact
     1141 ggtctggttc aatgataatg actggggtct tttaagaacc aggtattaga ggcccacgtg
     1201 tgtccctcag agagacagtg aaaatgctcg acttgaggtg gagtgagtgg aaggagaaag
     1261 gtttcatggc aggcaggcca ggcggcccag actaggggct ccatcttgcc cagcaagagg
     1321 tgcctcagcg cccatggccc agaccttcca ggaaaggata gcatccatta cttcaggctt
     1381 tatgtaccac agacttcaga ctcactgagc tccaggtccg atgcggaggg ggggaaaacc
     1441 ccacctaccc agagtgggta aaactgcagc ctcattgatg ctcccttagc gctcactggg
     1501 aagtctccat ggaaacaaga tgtagaggtc atgggttcag tggtgtgggc tcaggagttg
     1561 gaggagacct gacctcaggg cagggtatga gttctaagca gttgggagct tcaggggaga
     1621 aggttgggag tcacagacag ataggcaaag ctctgcacgg agcctgagag caaatgccat
     1681 tggagccctt cagtgtgcac tgggctgggg acaaggctct acacaccgaa ggcaaggcca
     1741 cggtggatct ggaggtggga cagttgactg tgtgtttgtc tcccatagga cacagcactg
     1801 gccactctcc ccagctctag ttcccaccct ccctgtgtag gccgagtgag tatcttggcc
     1861 gggtgaggag atgcatctgg ctagagatga tgaggtgtcg tgtttccttt ggttttaggg
     1921 tcacacacag cgtgtaaggg gatggaggtg gggcccagct agcatcagga gttctcaggg
     1981 cagaacggac ctaatggtat ctctctaggg agttactgcc ttcctttccc aaaaatccct
     2041 caaggtggtc tttcaactag aagcctaagg tctccctgac tcatttagga aactagagtt
     2101 tttagcccaa ctgttagaca ggcagggcac gtgaggaagg gactcagaga agagcaaagt
     2161 agggaagcag ggtagagaca agacttatgg cctggtgaca gtggagagac ccaggaacag
     2221 agggcagcct cagggtcaag gtaaaggctg gggtcacccc ggacctgagt gcctttggcc
     2281 caccagctct gacccccccc ccccaccttc ctgtctaact ccaagtgggc tatggacagt
     2341 acatccaggc ccccacaaaa catcaatggc agcatgtccc cagcccagtg tgcccaagga
     2401 ggcagctggc tacactgcat cagctcccag gcttgggaaa ggagacagct gaggaaaagc
     2461 atttcacctc atgcccggcc actttagaca actgcttatc aagacactgt gagaagagcc
     2521 caggacctag ggctctgctt tgtacttgct gtgggacctg gccagatcct ccatctcttt
     2581 ggacccacct tccccctctc tgttaactag aacttgttgt tccagatcct ggcactcagt
     2641 gcttcatctt gaatttactg tccaccccct gagttccccc cgcccctgcc ctgttttaaa
     2701 gacatagctt gaagctgttg gacttcccct gtgccttaac aactcgggac aaagtttggg
     2761 gctttctgga gccaggctaa gcaagatgga gtatgggcca gcagaaagaa ggaagggaga
     2821 gccagctttg ggcccagcgg actgataacc ccaacacatg cttaggcagc tgagttctct
     2881 ctgtaactcc ttgctggaca aaggctgagt tctgagtctc tcctgcccct cttattctct
     2941 gcccacaaac ctttaggtat cacagtgcag caaggttctt cctaggatag tgtgtgagga
     3001 ccagagccgg gggttcctgg gcagtttcca ggcaaatcca gatggcagca gacggtctca
     3061 atttccccac cttttcgagg caaaaaaaaa aaaaagcagt agctgagcca gatcctgaga
     3121 cagtttagga gaccagagac aaagttgact ttgctgctgt gcaagtaagt ggtcctggcc
     3181 cttcacggag tagttctcat gactaccgac agggagattc catgggcagg gacagagatt
     3241 gcccgagaag ggagggttga gccttgtctt tgtgctactg taacagaatt ccacatcctg
     3301 gtaatttata aacaatagaa gtttacttag cccgtggttc taacgtgaag cagaggagga
     3361 gcatctggtg agggctttct tgctgcgtca ttgtctgtat cacatggcta gagagcatgc
     3421 aaggggcagt caggacttcc gcgcacccgg ggagagagag ccccgctgac ccaatcaccc
     3481 tttaaacggc agacctgctg ggtttcccat gcatgtgctc tgagtaggcg gcactcaggg
     3541 tggagaagac agcactgacc aggaaggaag aaggaagcgt ggtgggggcc caacctggag
     3601 gcattgaaac atctttggtc cagacccatc acttcctagc agtgtggtcc atttgggagc
     3661 tagggcacaa atatccttgt tatcctgttg aagtgaggag gagatgaggt ttgaaaagag
     3721 gctgtcacag gactggggca agccagcatg atgcagtgtc tgttggtgag tccttcacct
     3781 gggctttctg tgtggtgaga tttggcaaga gctaggctga aacacattat ctatctatct
     3841 atctatctat ctatctatct atctatctat ctacctacct acctacctat ctatctatct
     3901 atctatctat ctatctatct atctatctat ctatctatct atctacctac ctatctatct
     3961 atctatctga ctgtctgtct atcatctatt catccattca tcatctatca ataaatctac
     4021 ccatcatcta tcaatcaatc tatccatcat ctatcagtca tctatcaatc atctatttta
     4081 gcactgagaa ttggactctg ggcctgaact atactaggca agtgcttttt caccatactc
     4141 cccccacccc ctctccttac ttagccagtc ttatggtgta gcctacactg ggctcaaact
     4201 tccaatcccc ctgcctctgt cttatgagtg ctaggatgac aggcctgtgt cactgtttct
     4261 agcgcaatct ctctgagaac ccagaatcgt gggcagctgg ttcctgatgc accaaggttt
     4321 tctctgggtg aaaaggaaag ctcactcgtc ctgggagagg gcctcggatc gccaccaccg
     4381 ctgctgtcgt ctccactaaa gaaaccttct gtactttctt cccagttaca tattttgtat
     4441 tgtattgttt tgttttaaac agtaatttac ttaaaaaaaa aaaaaacaaa caagctgtta
     4501 tgtactgggc gtggtggcac atgcctgtaa gccagtcttg gctatgtagt aagcatccgt
     4561 gacattgcaa cataataaag caaacacact gtgacaagtt t
//
