LOCUS       NM_028971               3988 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus leucine rich repeat containing 71 (Lrrc71), mRNA.
ACCESSION   NM_028971
VERSION     NM_028971.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3988)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3988)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3988)
  AUTHORS   Scavizzi,F., Ryder,E., Newman,S., Raspa,M., Gleeson,D.,
            Wardle-Jones,H., Montoliu,L., Fernandez,A., Dessain,M.L.,
            Larrigaldie,V., Khorshidi,Z., Vuolteenaho,R., Soininen,R.,
            Andre,P., Jacquot,S., Hong,Y., de Angelis,M.H., Ramirez-Solis,R.
            and Doe,B.
  TITLE     Blastocyst genotyping for quality control of mouse mutant archives:
            an ethical and economical approach
  JOURNAL   Transgenic Res 24 (5), 921-927 (2015)
   PUBMED   26178246
REFERENCE   4  (bases 1 to 3988)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB614807.1, AK016993.1, AK029938.1 and AC161454.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029938.1, AK016993.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                BB614807.1         1-73
            74-1932             AK016993.1         2-1860
            1933-3279           AK029938.1         1901-3247
            3280-3280           AC161454.3         138156-138156
            3281-3988           AK029938.1         3249-3956
FEATURES             Location/Qualifiers
     source          1..3988
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.46 cM"
     gene            1..3988
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /note="leucine rich repeat containing 71"
                     /db_xref="GeneID:74485"
                     /db_xref="MGI:MGI:1921735"
     exon            1..319
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..1836
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /note="leucine-rich repeat-containing protein C10orf92
                     homolog"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 71"
                     /protein_id="NP_083247.1"
                     /db_xref="CCDS:CCDS50946.1"
                     /db_xref="GeneID:74485"
                     /db_xref="MGI:MGI:1921735"
                     /translation="MSSEPSTTGTSPRTPRPGAQKSSGAVTKKGDRAAKDKTASTLPP
                     VGEDEPKNPEEYQCTGVLETDFAELCTRSGYVDFPKVVTRPRVQQSSVPSASTSEKPV
                     LDDQRPSASCSQSSLESKYVFFRPTIQVELEQEDSKAVKEIYIRGWKVEDRILGIFSK
                     CLPSLSQLQAINLWKVGLTDKTLTTFIALLPLCSSTLRKVSLEGNPIPEQSFSKLMGL
                     DSTIVHLSLRNNNINDHGAQLLGQALSTLQNSNRTLVSLNLAFNHIGDVGAGYIADGL
                     RLNRSLLWLSLAHNHIQDKGALKLAEVLRPFELTHREVVERRRLLLVKGTQERSRSPS
                     SSRYGDSKAEREKSQTLGISNVTLVDKQEKMQSLKAPKTISKKKEKTGEVVKKEEKLG
                     SGQSPTQGTPKKEDAAKAGKGKVTIPEQKMSKGKATKMGAKEKRSILLESEQLVVEAT
                     EMVNPLLEPVEHRDGKVFLPGNKVLLHLNLLRNQITEVGLEGFLTAVQYQVQVSKPKT
                     SPKAPLGLLWLSLAKNCFDPQCPTHVMIQELMLPRDPVKAKAREEEAAAT"
     exon            320..469
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            470..598
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            599..674
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            675..752
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            753..821
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            822..981
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1065
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1155
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1305
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1399
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1488
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1489..1603
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1725
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..3988
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1936
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /note="major polyA site"
     regulatory      2948..2953
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      2968
                     /gene="Lrrc71"
                     /gene_synonym="4933430H15Rik"
                     /note="major polyA site"
ORIGIN      
        1 tctttgcccg ttgctccggc cacagcccca cccaatcagg ctgggttgcc ctggagaggg
       61 cagtcgcgga gtcgcttggc tgagtggaga tcctaggggt gaggcccaca gagtcccgtt
      121 tcatcttgcc tctcactcga ggggtccaaa agcaccccta tgtcaagtga gccaagcact
      181 acagggacct cacccaggac tccgcgtcct ggggcccaga agtcatccgg agcagtaacc
      241 aagaaggggg atcgggctgc taaagataag acagcaagca ccctgccccc ggtgggagag
      301 gacgagccaa aaaatccgga ggagtaccag tgcacggggg tcctggagac agacttcgct
      361 gagctctgca cacggtcagg ctacgtggac tttcccaaag ttgtcacccg gccacgggtc
      421 caacagagct ctgtcccttc cgcctccacg tcagaaaaac ctgtcctaga tgaccagaga
      481 ccgtcggcat cctgcagcca gagcagcctg gagagcaagt atgtgttttt tcggcccact
      541 attcaagtgg agctggagca ggaggacagc aaggccgtga aggagatcta cattcgaggc
      601 tggaaagttg aagatcggat tctgggtatt ttctccaaat gtctgccctc cctcagccag
      661 ctgcaggcca tcaacttgtg gaaggtgggg ctgacggata agaccctgac cactttcatc
      721 gcccttttgc ctctttgttc ctccacactc aggaaggtat ctctggaggg gaacccaata
      781 ccagagcagt cctttagtaa gctgatggga ctggacagca cgattgttca cttgtctctg
      841 aggaacaaca acatcaacga ccacggggcg cagctcctgg gccaggcgct gtccacactg
      901 cagaacagca accgaaccct ggtttcactg aacctagcat tcaaccacat cggggatgtg
      961 ggcgcaggct acattgcgga tggcttgagg ctgaaccgct ctctcctctg gctgtcccta
     1021 gcgcacaacc acattcaaga caagggagca ctgaagctgg ccgaggtcct gcgccccttt
     1081 gagctgaccc acagggaggt ggtggagcgg cggcgcctgc tgctggtgaa aggaacgcag
     1141 gagcggtctc gatcgccttc ctcctcccga tacggggact ccaaagcaga acgtgagaag
     1201 tctcagacgt tggggatcag caatgtcact ttggtggaca agcaagaaaa gatgcagtca
     1261 ctgaaagccc ctaagaccat aagcaagaaa aaggagaaga caggggaagt tgtcaagaag
     1321 gaagagaagc tgggctctgg gcagtcaccc acacaaggaa cccctaagaa agaagatgcc
     1381 gcaaaggcag gcaaggggaa ggtaaccatc cctgagcaga agatgagcaa gggaaaagcg
     1441 acaaagatgg gggccaaaga gaagcgcagc atcctcctgg agtcagaaca gctggttgtt
     1501 gaagctacag agatggttaa ccctctcctg gagcccgtgg aacaccgaga tgggaaggtc
     1561 ttcttgcctg ggaacaaggt ccttttgcac ctcaacctcc tccgaaacca aatcacagag
     1621 gtggggctgg aaggcttcct cactgctgtg caataccagg ttcaggtctc caagcccaag
     1681 acttcaccca aggcccccct gggtctgctg tggctgtcct tggcgaaaaa ctgctttgac
     1741 ccacagtgtc caacacacgt catgattcaa gaactgatgt tgccaaggga ccctgtgaag
     1801 gccaaggcca gggaggagga ggctgcagct acctaggtct cctacaggca gcctgtctcc
     1861 ctgggaggta gcttggacca gtaacatagt ctcttgctgt gctgttcctt gaaaatcact
     1921 ccatacctgt ttggaacgtt taggttctta agtctgttca tattccctgg ctagacaggg
     1981 ccgaatgttg gcctgaatca caccatggtt ccattggggg atgagctgag ctcctggcta
     2041 gggccattgc tctgagagtc ccagcagcat cctccgggcc atctctgtca gcatgcacag
     2101 cactaggatg atgggggttg gttagcacaa tgacggaggg agcgggcttg gaacccagcc
     2161 ttctctgatg ctatctccat gtgtttgtct ggttttccag aggccagggc tctgctttaa
     2221 aagatgaggg cactctggag agggtactgt atccaatttg cataacaaag gccaaacctt
     2281 agacacacgt acacacggca ggcaggtcag caactagaaa tcatggacat ccagagcagg
     2341 gctgcctctg ctgagggttc tggagagccc atgccaacct ccagggaatc tccaaccaag
     2401 gtaactctcc ctcatctcta gcccctcctc taccttccag agctccagcc ccggctggca
     2461 agtggctctg gggatctctc cggctgctct gagtctcagt cactgtgtta aggtgcacca
     2521 tggcttttcc agttatgtcc caggtcctct aaggcatggc tcagctgcca tggctcttcc
     2581 tggtctgtgg gaaggagggc agtgtggtaa ccctcttcat ggtttgcatc tgagagtagg
     2641 tcacagcagc cctgttcctt cgtgtgacgt aaccacaatg tccttttctg ggccagagcc
     2701 agttgtccaa cctctgctga gaaggtctac acaccggcac tttgggacag gtggaaagac
     2761 ctggtgcagg atggctgtgg caggggcttt cttgtctccc tctacccatt tttgaccggt
     2821 cacaccggca gcctcacacc ctctatcagg ctaagaatca tacaaccaca atggaagaat
     2881 atttaacttt tctttaaaaa aatcttaacc atgaaaggaa gaaaataaga gtatacatta
     2941 ttttaacagt aaaacagtca tttccatatc tatattttat atattatata tatttatata
     3001 tatgtatata tacacctagc acagtgtgta tgttcattgt agggagtggc gtgaggacag
     3061 ggtgatgagc caacggtgct gtggcccctg gggaaggaag ggccctgact taactcaggg
     3121 actccagcaa tccactccac atctctcttg agagtctgtg ttgagatccg tacctggtgt
     3181 attgtttcta tggggcaagt ggggaagggc tgggtaagac actccctgca ggagcatttc
     3241 ctgacactga gaaggcctag gcttcagagg tgggcaggcc ctggagcttg acagcactgg
     3301 aatctgggag acctccctgc cagtgggaca taaacaatca tggccctgtg cggggctgct
     3361 gcctggctct ctgtgactgg ttgaacatgc cagggacaga ataaaaggct aagttattta
     3421 caatggcaaa gatacacata caatagacat atttatagga aactaaaggg caaagaggag
     3481 agccaggcat ctagctgtct cggggcctag gaagaagagg aggaagaaag tgcatttata
     3541 cataagcctc ctcaagggca ctgtgcacat agcacacccc acactggcta tgtggggtgg
     3601 aggcctttct attgtggtca gcatgcttag gagacgaaag ccacggagac ttgggctaac
     3661 aggaggaaga gacactaaac tggactgtct ggtgggaaca gaccaggcaa catgagggat
     3721 tcccaggcct cacagtatct ttcacgggga ggctcggatc tcctaatgtg gcgctctggc
     3781 tcaggccaga ctctggttgt ctggatggct atggtcctgg tgacgaagct gtgtctgtgg
     3841 cactgtcttc caggggggtg tcggagcctg tgggaagatg gtgagggtga gacgctggct
     3901 acatttgaga ggttctcttt catgtccctg gctgattctt gagtgccagc tgtgacaaag
     3961 cttatatgta atagagtgtg tggaagct
//
