LOCUS       NM_001404637            2797 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus leucine rich repeat containing 63 (Lrrc63), transcript
            variant 2, mRNA.
ACCESSION   NM_001404637 XM_006519545
VERSION     NM_001404637.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2797)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129591.4.
            
            On Apr 12, 2022 this sequence version replaced XM_006519545.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.114114.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-391               AC129591.4         90943-91333
            392-561             AC129591.4         92224-92393
            562-1257            AC129591.4         95293-95988
            1258-1401           AC129591.4         96590-96733
            1402-1562           AC129591.4         98762-98922
            1563-1661           AC129591.4         100773-100871
            1662-1798           AC129591.4         114437-114573
            1799-1882           AC129591.4         123551-123634
            1883-2113           AC129591.4         135521-135751
            2114-2797           AC129591.4         136872-137555
FEATURES             Location/Qualifiers
     source          1..2797
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 39.59 cM"
     gene            1..2797
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /note="leucine rich repeat containing 63"
                     /db_xref="GeneID:70859"
                     /db_xref="MGI:MGI:1918109"
     exon            1..391
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            392..561
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             438..2354
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 63"
                     /protein_id="NP_001391566.1"
                     /db_xref="GeneID:70859"
                     /db_xref="MGI:MGI:1918109"
                     /translation="MKKSIYRSLKTQQHPLLLRRPLPPKLPKVPLLKKKVRIVHTVKA
                     REPKEETYGKFDPDESAFVKMDQNVSQSQRPTSTQTICLDYDHKALERVVNIFPHQHR
                     VRRFHWKVPKSTAGSMFIPRCLSASSRIFKNTLSQMKKRAKKSSKKEVKEDGYLTKKT
                     FNTLVLSKEFSKPSPTSYSRFIASKFKPLGTQFHPAPKISGYSQELPLLRDVKRAALS
                     PVPSTSSVIPEPQWSERTHPSAAPSKVVLNTGSLPPARSLPTPVLPRKPLRQAMIENA
                     AAAAAAAAAAAAATTTTTTTTTTTTTAVTTTAAVSGKTEAHKPPETVQRTTRTIGPDA
                     HVLRGEGFKAVAATRSETVLALTTLAIINCQIYGRNALNLKGFFLANCPDLTPVAFQL
                     VYLNLSFNDLNQFPIEILYLQNLQVLKLRNNPIKEIPSEIHLLTYLRIFSIAFNYITK
                     LPDGLFCLNYLEELDVSYNEIENISNEIQKLRSLEKLIVDGNPITSFPPGILKLNLIK
                     LQIENTFTCSQFWLESSWNDPQQLTQICSLFLVKNKLLDYIPDAVRKSLKSTSECDWC
                     HGPKFGEGFRIIRSCDIFGVSHVPIMFHVCSSTCYRDIRETSFVLEGFPSRRIALHMD
                     WVKESKVSNVSFYL"
     exon            562..1257
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1401
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1562
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1661
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1798
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1882
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..2113
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2797
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2774..2779
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2797
                     /gene="Lrrc63"
                     /gene_synonym="4921509B22Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtaattcggc tgtagcaggg cttggggatg ctgctaaagg agctgcgtcc agcacaaaca
       61 tggaattaga cctaactgga gacctcgcta gacagtcact ggcagccagg actcagggat
      121 aaaggagatg gacgtgggaa atctggtctg tgtgcttgaa ggcagggtcc gtaggagctg
      181 gacacttggg gactgggggg tggtgatggg gtctccccac caactagaaa aggaaacttg
      241 tggcgggcgg gcacgcgcta ccagccgaca aatcaggagc gagcgctggc ctgcagttac
      301 ctttcgcggg taaaccgctc ttctgcaccg caccagggtt ccctgcctgc cgggcattcc
      361 gcggagctgc actgtgccag gcacttttga gtaacgattc gttctcagga agttcagttc
      421 tcacttaacc agcagctatg aaaaagagca tttatcgctc actcaaaacc cagcagcatc
      481 cactacttct gcgaagaccc ttacctccaa agctccctaa agtaccttta ttaaaaaaga
      541 aagttcgtat agtacataca gttaaggcta gagaaccgaa ggaggagacc tatggaaagt
      601 tcgatcctga tgaaagtgct ttcgtgaaaa tggatcaaaa tgtttctcaa tcacaaagac
      661 ctaccagcac tcaaaccatc tgtcttgact atgaccataa ggcactcgaa agagtggtta
      721 acatttttcc acatcaacac cgtgttcgcc gttttcactg gaaggtccca aagagcaccg
      781 ctggttccat gttcattcca agatgtctgt cggcgtcttc cagaattttt aagaatacgc
      841 tatcccaaat gaaaaaaaga gccaagaagt cctcgaaaaa ggaagtcaaa gaagatgggt
      901 atctcactaa aaagacattt aacactttag ttctttccaa ggagttttcc aaaccttcac
      961 ccacttctta ctctagattc atcgcatcta agtttaagcc actaggtacc cagtttcacc
     1021 ctgcaccaaa gatttcaggc tatagtcaag agctccctct tctcagagat gtaaagaggg
     1081 cagcactcag ccctgtacct agcacttcat ctgtaatacc tgaaccgcag tggtctgaac
     1141 ggacacaccc ttcggcagcc ccaagtaaag tggtactgaa cactggctca ctcccgccag
     1201 cccgttctct gccaacgcct gttttgccaa gaaaacctct aagacaggct atgatagaaa
     1261 atgctgctgc tgctgctgcc gctgccgccg ccgccgccgc cgccaccacc accaccacca
     1321 ccaccaccac caccaccacc accgctgtca ccaccaccgc tgcagtgagt ggaaaaacag
     1381 aagcccacaa accgcctgaa actgttcaga gaaccaccag aacaataggc ccagatgccc
     1441 atgtcttacg aggggaaggc tttaaggctg ttgcagcaac acgctctgaa acagtactgg
     1501 cgctgaccac cctggccata ataaattgcc aaatatatgg aagaaatgca cttaatctta
     1561 agggattctt tctagcaaac tgtccagact taacacctgt ggcttttcaa ttggtatacc
     1621 ttaatttatc atttaatgac ttaaaccaat ttcctataga aatactttat cttcaaaacc
     1681 tacaagtact gaaattgaga aataacccta tcaaagaaat tccttctgaa atccatctat
     1741 tgacatacct taggattttc tccattgcct ttaattatat tacaaagctt cctgatgggt
     1801 tattttgcct gaattatctt gaggagctcg atgtttccta caatgaaatt gaaaatattt
     1861 caaatgaaat ccagaaactc agatcacttg aaaaactgat tgttgatggg aatcccataa
     1921 cgtcttttcc acctgggatt ttgaagctta acttgatcaa attacaaatt gaaaatacat
     1981 tcacttgttc tcagttttgg ttagagagtt cctggaatga cccccaacaa cttactcaaa
     2041 tttgctcctt gttccttgtt aaaaataaac tgttggatta catcccagat gcagttcgga
     2101 agtctcttaa aagcacatct gaatgtgatt ggtgccatgg tcccaagttt ggtgaaggtt
     2161 tccgcatcat ccgatcctgc gatatctttg gagtatcaca tgtccccatt atgttccatg
     2221 tctgctcctc tacttgctat cgggacatca gggaaaccag ctttgtttta gaaggtttcc
     2281 ctagtagaag aatagctcta catatggact gggtaaaaga gagcaaagtc agcaatgtct
     2341 cgttctattt gtaaaaccca caaatatttc tgtataagta attcacctct tagagcacgg
     2401 gttctgcaag gagggaccca tggttcttct ctgctgagtt ctctctgatc ctcctcctca
     2461 cgaaagcctg attgttagaa atcggtgctg agctctgact caaggagtag gaaaggcctt
     2521 tggagttcag tagggacctt gagaagttcc tggagaacac gtttatagta aagggggggg
     2581 ggggttcaaa acatttgcca aaagaactgc atcttatact ttgtcttttc atggacctat
     2641 attcaatgac aggctagcag cttgaagcca ttatggggaa ctatgttgca cgaggccaca
     2701 aagttatgtg tccaggtact aaatgttagc tcgtgcaccc tcctcaatgc caaccggctg
     2761 gttttcttct gagaataaaa gattaattgc aaactga
//
