LOCUS       NM_133807               2846 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus leucine rich repeat containing 59 (Lrrc59), mRNA.
ACCESSION   NM_133807
VERSION     NM_133807.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK159552.1 and CX203638.1.
            
            On Jul 6, 2018 this sequence version replaced NM_133807.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159552.1, AK159374.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2827              AK159552.1         4-2830
            2828-2846           CX203638.1         473-491
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 58.9 cM"
     gene            1..2846
                     /gene="Lrrc59"
                     /note="leucine rich repeat containing 59"
                     /db_xref="GeneID:98238"
                     /db_xref="MGI:MGI:2138133"
     exon            1..333
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     CDS             229..1152
                     /gene="Lrrc59"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 59"
                     /protein_id="NP_598568.1"
                     /db_xref="CCDS:CCDS25261.1"
                     /db_xref="GeneID:98238"
                     /db_xref="MGI:MGI:2138133"
                     /translation="MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVL
                     DLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPV
                     SFAQLKNLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQ
                     RRLEVEREAEKKREAKQQAKEAKERELRKREKAEEKERRRKEYDAQKASKREQEKKPK
                     KEANQAPKSKSGSRPRKPPPRKHTRSWAVLKVLLLLLLLCVAGGLVVCRVTGLHQQPL
                     CTSVNTIYDNAVQGLRHHEILQWVLQTDSQQ"
     exon            334..393
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     exon            394..552
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     exon            553..657
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     exon            658..730
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     exon            731..904
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     exon            905..2834
                     /gene="Lrrc59"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2805..2810
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc59"
                     /note="hexamer: ATTAAA"
     polyA_site      2827
                     /gene="Lrrc59"
                     /note="major polyA site"
ORIGIN      
        1 agtggtcgtc gtcgcggcgg caccggtggg agcggggccc tgggctggga gtgcggcggg
       61 cgagcggacg ggcggcggag gcctcgcagc ggcggcggag gcgacggcgg cttaaggcgc
      121 aggcgtggtc cgttgggtgt gagtccgccg agcccacgag cggcccctca tccctctctc
      181 ctgcccgtcg gaaaccggga gccagggacc cgcttagccg gcgtcatcat gaccaaggcc
      241 ggtagcaagg gcgggaacct ccgcgacaag ctggacggca atgagctgga cctgagcctc
      301 agcgacctga atgaagtccc cgtcaaggag ctggctgcac ttcccaaggc tacggtattg
      361 gatctgtcct gcaataaact gagtactctt ccgtcggatt tctgtggcct cacacacctg
      421 gtaaagctgg acctcagcaa gaacaagctg cagcagctac ccgcagactt tggccgcctg
      481 gttaaccttc agcatttgga tctcctcaac aacaggctgg tcaccctgcc tgtcagcttt
      541 gcccagctca agaatctgaa gtggctggat ctgaaggaca atcccctgga ccctgtcctg
      601 gccaaggtgg caggtgattg cttggatgag aagcaatgta agcagtgtgc aaacaaggtg
      661 ttacagcaca tgaaggccgt gcaggcagat caggaacgag agcggcagcg ccggctggaa
      721 gtggagcgag aggcagagaa gaagcgtgag gccaagcagc aagctaagga agcgaaggag
      781 cgcgagctgc ggaagcggga gaaggcggag gagaaggagc gccggcggaa ggagtatgac
      841 gctcagaagg cgtccaagcg ggagcaagag aagaagccta agaaagaggc aaaccaggcc
      901 ccgaaatcga agtctggctc tcgtcctcgc aagccaccac cccgaaaaca cactcgctcc
      961 tgggctgtgc tgaaggtgtt gctgttgctc ctgctgctgt gtgtagcagg agggctggtt
     1021 gtatgccggg tgacagggct gcaccagcag cccctctgca ccagcgtgaa caccatctac
     1081 gacaatgcgg tccagggcct gcgtcatcat gagatcctcc agtgggtcct gcaaaccgac
     1141 tcccagcagt gagctcaccc tcagcacccg ctgcctccca gccttggagc ttggattcct
     1201 atggaattgg gttctgctgg acacaacctc tttttagcgt cagacctacc tgccatcatc
     1261 acatggctgc tggtggtact tgagatctcc cctttgtagg acttctgttc catagtcagg
     1321 gttccctggt ggaatgagga gaaatggaga ggggggagga agagttacct gcatgcctaa
     1381 aggagtaggc ttaggggtgg ggagagagaa ggcataggct tttctagtta tacaaagctg
     1441 tgtaaggcaa ggttcctttc tactaaatgg tcagctgtca ctacatttat acttttgtat
     1501 gtcataaacc ctttctttca ttcctccctg ggtaaccagg acaatcggag ggcagtgtgt
     1561 tactgggatt agaggactag caatactggg taacccagcc taagctggga aggtgacgta
     1621 atacgtttct ttaaagattc agtcagtcaa gcagtttagc aatatccaaa atgtctggct
     1681 gtttggtcca gtgtcacatg ttgaggcagg aggtgccgtc tcatccatga cttgccagca
     1741 gtgttcaggc tagtctgagg cacaaccagg ctctcattcc agttttcctc cttcccttta
     1801 tgtcattcga cctcctatat aatacccaag aggatgaact cacaccagag ttgtctcagc
     1861 taaagcgaat ctttcataac agtcttacca cccacaaata gatctcatat catcagggtc
     1921 ctgggaaact taactcctgt ggaattttgc ctcaactttt aaatggcttc cacaaaatgg
     1981 cagcaggccg ggttccttgc ctcagtttta gagcattaac tcccgaatgg cctggaagca
     2041 gagggaactc tgcaaagccg tactgtggct gctccactag cactcggtgt gatgaaatac
     2101 ctcaaaggca acctagaaac ttgacttcat ggaagcaggt ttagagttga ttctggacct
     2161 gtaacagaag ggaaggaagg aagagaacag tgggagtcaa agggaaacaa agtcacatgg
     2221 tggcgctgca gagtgataca taactaaaca ttagcacaac cagggcagag ccgcccacct
     2281 ccctgctgct acaagaaagc attctcccct ttcccagtct cttcacaaca gctgcatgaa
     2341 gggatcagaa acaactgtgt ctcggtgctt acttgctaaa aactcccatt tgcaagctcc
     2401 ctagaggagc aaggacctgt catagttcag cagtgtagcc ctagtggccc atctggatag
     2461 gtctgccatt caaaactgtc ctgacactgg aagaaaggcc ttggattttt cctccccaga
     2521 cagttctgcc atgtaggccc acacctcctc agcatcacct cctcagcatc actacacgct
     2581 cctttagtct tcctccaagc tccacagcca ttggtacaaa ggctttattg agacaaaata
     2641 catactacat acatatggtg acatcatgaa aacaggagtc agcctcatca tagctcccta
     2701 gctggttgag gcagctcagt ggctgggcgt agtcaagcca acccgcaggc aagagttcac
     2761 tctgacttcg agatttgatg cttatttctt ggatttctac aattattaaa tccatgtctg
     2821 agtggtctgc ctttaaaaaa aaaaaa
//
