LOCUS       NM_001159612            1982 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus leucine rich repeat containing 57 (Lrrc57), transcript
            variant 4, mRNA.
ACCESSION   NM_001159612
VERSION     NM_001159612.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1982)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ169080.1 and BC034894.1.
            
            Transcript Variant: This variant (4) differs in the 5' UTR and
            coding sequence compared to variant 1. The resulting isoform (c) is
            shorter at the N-terminus compared to isoform a. Variants 3 and 4
            both encode isoform c.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012637.1, AK169249.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-426               CJ169080.1         3-428
            427-1553            BC034894.1         269-1395
            1554-1982           BC034894.1         1397-1825
FEATURES             Location/Qualifiers
     source          1..1982
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..1982
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /note="leucine rich repeat containing 57"
                     /db_xref="GeneID:66606"
                     /db_xref="MGI:MGI:1913856"
     exon            1..244
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            245..350
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..986
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /note="isoform c is encoded by transcript variant 4;
                     leucine-rich repeat-containing protein 57"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 57
                     isoform c"
                     /protein_id="NP_001153084.1"
                     /db_xref="CCDS:CCDS16623.1"
                     /db_xref="GeneID:66606"
                     /db_xref="MGI:MGI:1913856"
                     /translation="MGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTID
                     LSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPS
                     TFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNL
                     NQNQISQLSVKISCCPRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKL
                     RELEGYDKYMERFTATKKKFA"
     exon            351..489
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            490..758
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            759..944
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1965
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1304..1309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /note="hexamer: CATAAA"
     polyA_site      1322
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
     regulatory      1946..1951
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1965
                     /gene="Lrrc57"
                     /gene_synonym="2810002D13Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggcggaagcc ctgggagcgc gtctcaggcg agcgcgggtc cccggtgttc cctggcggag
       61 tcttctttgc actgagcggt aggaggcgag tctcaagctc cctgttccgg cagcagctat
      121 cggaggctcc ctggccctta gctctgctgc caaagcatca ggaccttgtg gtagcgctgc
      181 ctgctcgcct gttttctcct tgccactctt gggctggccc cagggaagta gggataggca
      241 gaagggaact gagccgtggc gctaggatgg gtaacagtgc tctccgtgct catgtggaaa
      301 cagcgcagaa aactggtgtc tttcagctta aagaccgtgg tctgaccgag ttcccctcag
      361 agttgcagaa gctgacaagc aatcttagga ccatcgattt atccaacaac aagattgaca
      421 gcctaccgcc tctgataata ggaaagttca ctctgctaaa gagcctctcc ctcaacaaca
      481 acaaactgac tgttctacct gatgaattat gcaatctgaa aaaactagag acactaagtc
      541 tcaacaacaa tcacctgaga gagctaccat ctacctttgg gcagttgtct gccctgaaga
      601 cgctgagcct ctctgggaat cagctgggag cattaccccc ccagctttgt tgcctgagac
      661 atctagatgt agtagatctc tctaaaaacc agattcggag tatacctgac acagttgggg
      721 agctgcaggc catcgaactc aatctcaacc agaaccagat ctctcagctc tctgtgaaga
      781 tatcctgctg tcctcgcctc aaggtcctcc ggctggaaga gaactgcctt gagctcagca
      841 tgcttccaca gagcatcctc agtgactccc aaatctgcct gcttgctgtg gaaggcaatc
      901 tctttgaaat aaagaaactt cgagaactag agggttatga taagtacatg gagaggttca
      961 cagccaccaa gaagaaattt gcatgatatt ctccaggatc atgggacaga cttggaacct
     1021 ctgttgaaat ctgactgagt caaaggctcc tgatgttgga tacactgcag agaacatttt
     1081 acttaatgac tttttccttt ttaggactat gtcagataag ctgaaggaaa gggatttagg
     1141 agtaggagac aggaagaacc cttcatcttg agccgtgtag gtcatggcca gtgttgatct
     1201 tcaaaactat cattagttgg gctctaagga acctgctgtt catgaaggga ggaaatgctg
     1261 cttgccatag ctggagactt tgagtttgcg aactgtcagc tttcataaag tctttcccat
     1321 cacctctgtg ttaatacttc atatttttta tgaaattcta atttgtggga aacgtatgac
     1381 taaggatgaa tgtgtttgtt cctgtacact aactcaatag cagtgtttac acttggaact
     1441 taggatgtac ctaaatatgt agctgtcttg aagagacctt tgtcaaagga gcaccaacac
     1501 aacagccacc gagaatgttc cccaaggctg cagtagcaaa tttttttttt tttactattg
     1561 caggtgcctt attggtagaa ggctctgaaa gagctaaaac tatatgcaaa aattatacaa
     1621 aatttttgtt tttagacagg tttttgctat gtagcccagg ctggcctcag actcaaaatc
     1681 tcccaacctc acacctctcc cctcccccac atgctgggat tgtaggcatg cgctacactc
     1741 agcctacttg taggatttta aattaatttt aataatcaag attttcctga agctttgtta
     1801 aaaatcatgt gctatttctg gtaactcctc ccccttttgt atttataact gtactaatca
     1861 gattaccttc aagaaaacca ttgctacaat attttaaaat aacttatgtt tatcatagtt
     1921 actctctgaa tgagagaata ttctaaataa aatattttta atgaaaaaaa aaaaaaaaaa
     1981 aa
//
