LOCUS       NM_198250               2753 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus leucine rich repeat containing 4B (Lrrc4b), mRNA.
ACCESSION   NM_198250 XM_907133
VERSION     NM_198250.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2753)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2753)
  AUTHORS   Lee,H., Shin,W., Kim,K., Lee,S., Lee,E.J., Kim,J., Kweon,H.,
            Lee,E., Park,H., Kang,M., Yang,E., Kim,H. and Kim,E.
  TITLE     NGL-3 in the regulation of brain development, Akt/GSK3b signaling,
            long-term depression, and locomotive and cognitive behaviors
  JOURNAL   PLoS Biol 17 (6), e2005326 (2019)
   PUBMED   31166939
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2753)
  AUTHORS   Maruo,T., Mandai,K., Miyata,M., Sakakibara,S., Wang,S., Sai,K.,
            Itoh,Y., Kaito,A., Fujiwara,T., Mizoguchi,A. and Takai,Y.
  TITLE     NGL-3-induced presynaptic differentiation of hippocampal neurons in
            an afadin-dependent, nectin-1-independent manner
  JOURNAL   Genes Cells 22 (8), 742-755 (2017)
   PUBMED   28695613
  REMARK    GeneRIF: NGL-3 induced differentiation of hippocampal mossy fibers.
            This activity of NGL-3 was dependent on afadin, but not the
            afadin-binding presynaptic nectin-1.
REFERENCE   4  (bases 1 to 2753)
  AUTHORS   Gu,Z., Imai,F., Kim,I.J., Fujita,H., Katayama,Ki., Mori,K.,
            Yoshihara,Y. and Yoshida,Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2753)
  AUTHORS   Wentzel,C., Sommer,J.E., Nair,R., Stiefvater,A., Sibarita,J.B. and
            Scheiffele,P.
  TITLE     mSYD1A, a mammalian synapse-defective-1 protein, regulates
            synaptogenic signaling and vesicle docking
  JOURNAL   Neuron 78 (6), 1012-1023 (2013)
   PUBMED   23791195
REFERENCE   6  (bases 1 to 2753)
  AUTHORS   Yoshida,T., Yasumura,M., Uemura,T., Lee,S.J., Ra,M., Taguchi,R.,
            Iwakura,Y. and Mishina,M.
  TITLE     IL-1 receptor accessory protein-like 1 associated with mental
            retardation and autism mediates synapse formation by trans-synaptic
            interaction with protein tyrosine phosphatase delta
  JOURNAL   J Neurosci 31 (38), 13485-13499 (2011)
   PUBMED   21940441
REFERENCE   7  (bases 1 to 2753)
  AUTHORS   Mandai,K., Guo,T., St Hillaire,C., Meabon,J.S., Kanning,K.C.,
            Bothwell,M. and Ginty,D.D.
  TITLE     LIG family receptor tyrosine kinase-associated proteins modulate
            growth factor signals during neural development
  JOURNAL   Neuron 63 (5), 614-627 (2009)
   PUBMED   19755105
REFERENCE   8  (bases 1 to 2753)
  AUTHORS   Homma,S., Shimada,T., Hikake,T. and Yaginuma,H.
  TITLE     Expression pattern of LRR and Ig domain-containing protein (LRRIG
            protein) in the early mouse embryo
  JOURNAL   Gene Expr Patterns 9 (1), 1-26 (2009)
   PUBMED   18848646
REFERENCE   9  (bases 1 to 2753)
  AUTHORS   Kim,S., Burette,A., Chung,H.S., Kwon,S.K., Woo,J., Lee,H.W.,
            Kim,K., Kim,H., Weinberg,R.J. and Kim,E.
  TITLE     NGL family PSD-95-interacting adhesion molecules regulate
            excitatory synapse formation
  JOURNAL   Nat Neurosci 9 (10), 1294-1301 (2006)
   PUBMED   16980967
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC060263.1.
            
            On Dec 7, 2005 this sequence version replaced XM_907133.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060263.1, CX204940.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2753
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.83 cM"
     gene            1..2753
                     /gene="Lrrc4b"
                     /gene_synonym="A830007M12; Lrig4; Ngl3"
                     /note="leucine rich repeat containing 4B"
                     /db_xref="GeneID:272381"
                     /db_xref="MGI:MGI:3027390"
     exon            1..45
                     /gene="Lrrc4b"
                     /gene_synonym="A830007M12; Lrig4; Ngl3"
                     /inference="alignment:Splign:2.1.0"
     exon            46..383
                     /gene="Lrrc4b"
                     /gene_synonym="A830007M12; Lrig4; Ngl3"
                     /inference="alignment:Splign:2.1.0"
     exon            384..2726
                     /gene="Lrrc4b"
                     /gene_synonym="A830007M12; Lrig4; Ngl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcctggggc acagagagaa ggccatcgga agccaagccg ccaggccccc cagcgtgccc
       61 tcggagtatg aacattgagg atggcgcagg cccacatccg cggctccccg tgccccttgc
      121 tgccgcctgg taggatgtcc tggccccacg gggctctctt gctcctgtgg ctcttctccc
      181 cacccctgag ggctggtggg ggcggtgtgg ccgtgacctc agccgctgga ggaggctccc
      241 cgccagccac ctcctgccca gccgcctgct cctgcagcaa ccaggccagc cgggtgatct
      301 gcacgcggag ggagctggcc gaggtgccag ccagcatccc tgtcaacacc cgctacctga
      361 acctgcaaga gaacagcatc caggtgatcc gcacggacac attcaagcac ctccggcacc
      421 tggagatcct gcagctgagc aagaacctgg tgcgaaagat cgaggtggga gcgttcaatg
      481 ggctgcccag tctcaacaca ctggaactct tcgacaaccg gctgacaacc gtgcccacgc
      541 aggcctttga gtacctgtcc aagctccggg agctgtggct gcgcaacaac cccatcgaaa
      601 gcatcccatc ctatgccttc aaccgtgtgc cctcactgcg ccgcctagac ctgggcgagc
      661 tgaagaggct ggagtacata tctgaggcgg ccttcgaggg gctggtgaac ctgcgctacc
      721 tcaacctggg catgtgcaac ctaaaggaca tccccaacct cacagcactt gtgcgcctgg
      781 aggagctgga gctgtccggg aaccggctgg acctaattcg ccctggctcc ttccagggcc
      841 tcaccagcct gcgcaagctg tggctgatgc atgcccaagt ggccaccatc gagcgaaacg
      901 ccttcgacga cctcaagtcg ctggaggagc tgaacctgtc ccacaacaac ctgatgtcgc
      961 tgccgcacga ccttttcacg ccccttcacc gcctggagcg tgtccacctg aaccacaacc
     1021 cctggcattg taactgtgat gtgctgtggc tcagctggtg gctgaaggag acagtgccca
     1081 gcaataccac atgctgcgca cgctgccacg cgcccgccgg cctcaagggc cgctacattg
     1141 gcgagctaga ccagtcgcac ttcacctgct atgccccggt catcgtggag ccacccacag
     1201 acctcaatgt caccgagggc atggcggctg agctcaagtg ccgcacaggc acatccatga
     1261 cgtcggtcaa ctggctgaca cctaacggca cgctcatgac gcacggttcc tatcgtgtgc
     1321 gcatttcagt gctgcacgat ggcacactca acttcaccaa tgtcaccgtg caggacacgg
     1381 gccagtacac gtgcatggtg acaaactcgg ctggcaacac tactgcctcg gccacgctta
     1441 acgtgtcggc cgtggacccc gtggctgcgg gagggcccgg tggcgggggc ccagggggtg
     1501 ggggcggtgc agggggcgcg ggcggataca cctacttcac cacggtgacc gtggagacgc
     1561 tggagacgca gccgggggag gaggcccagc agccccgagg tactgagaag gagcccccgg
     1621 ggcccacgac tgatggcgcg tggggcggcg gccggcctga tgctgcagcc ccggcctcgg
     1681 cgtccaccac ggcaccggcc ccgcgctcct cgcggcccac ggagaaggct ttcacggtgc
     1741 ccatcacgga cgtgacggag aatgcgctta aggacctaga cgatgtcatg aagaccacca
     1801 aaatcatcat cggctgcttc gtggccatca ccttcatggc cgccgtgatg ctggtggcct
     1861 tctacaagct gcgcaagcag caccagctgc acaagcacca cgggcccacg cgcactgtgg
     1921 agatcatcaa cgtggaggac gagctgcccg ccgcctccgc tgtgtcggtg gctgcggccg
     1981 ccgcggtggc tggaggcgcg ggcgtgggtg gggacagcca cctggccctt ccggcgctgg
     2041 agcgagacca cctcaatcac caccactacg ttgcggccgc cttcaaggcg cactacggcg
     2101 gcaacccggg aggcgggtgc ggggccaaag gccccggcct caactccatc cacgaacctc
     2161 tgctcttcaa gagcggctcc aaggagaacg tgcaagagac acaaatctaa acccaggcgc
     2221 acgggacgcg ggacgcctgc ccgagatgct cctgcttgcc gagcaaccct ggcggcgcct
     2281 gcgggtcctg caatgggaaa ggacctgggg accaggagag gtggccccgc cctccgcctt
     2341 gccgcgtcct ctgccctcct gccctgcccg ccaccttcca ggggttgagg agcttcttcg
     2401 aggggtaccc ttttctcctc accccaacaa ccctcctttt atggctcttt ttttttcttt
     2461 tcttttcttt tttttttttc ttttgcagtt tgacgcctgt ccttccctcc tactccttca
     2521 ccctcaaaac acaagagaca ggcaacttca ccagagccca gggggcaact ccgacaatgc
     2581 ccccaacagc gagctccact cgcggccctg gcaggcccac cccaccccac agactctttt
     2641 gatactgaag ggaggtttgc gtcaatcact acctgctctg taattacttt aaaaaaaaaa
     2701 aaaaacacgg aaaaagtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
