LOCUS       NM_027026               1338 bp    mRNA    linear   ROD 11-SEP-2024
DEFINITION  Mus musculus leucine rich repeat containing 46 (Lrrc46), mRNA.
ACCESSION   NM_027026
VERSION     NM_027026.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Jiang,L., Dai,C., Wei,Y., Zhao,B., Li,Q., Wu,Z., Zou,L., Ye,Z.,
            Yang,Z., Huang,L. and Shi,Y.
  TITLE     Identification of LRRC46 as a novel candidate gene for high myopia
  JOURNAL   Sci China Life Sci 67 (9), 1941-1956 (2024)
   PUBMED   38874710
  REMARK    GeneRIF: Identification of LRRC46 as a novel candidate gene for
            high myopia.
REFERENCE   2  (bases 1 to 1338)
  AUTHORS   Yin,Y., Mu,W., Yu,X., Wang,Z., Xu,K., Wu,X., Cai,Y., Zhang,M.,
            Lu,G., Chan,W.Y., Ma,J., Huang,T. and Liu,H.
  TITLE     LRRC46 Accumulates at the Midpiece of Sperm Flagella and Is
            Essential for Spermiogenesis and Male Fertility in Mouse
  JOURNAL   Int J Mol Sci 23 (15), 8525 (2022)
   PUBMED   35955660
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1338)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC022723.1.
            
            On Jun 19, 2003 this sequence version replaced NM_027026.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022723.1, AK158517.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 60.65 cM"
     gene            1..1338
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /note="leucine rich repeat containing 46"
                     /db_xref="GeneID:69297"
                     /db_xref="MGI:MGI:1916547"
     exon            1..287
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..1237
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 46"
                     /protein_id="NP_081302.2"
                     /db_xref="CCDS:CCDS25311.1"
                     /db_xref="GeneID:69297"
                     /db_xref="MGI:MGI:1916547"
                     /translation="MPGDEQEAKKAAQRTEEGVHITEALITKRNLTFPGDEDLSEKMF
                     HTLGELETVRLDGEGITCIGNLEKLRNIHSLYLQSNKIQRIENLACITSLRFLSLARN
                     QIRHVENLLDLQYLQFLDLSENLIETLKLDELPESLLILNLCGNPCTNQEGYRKMVIG
                     ALPLLLDLDKQPILERWTSDEEDKSSDDDDEFPELNGPFCAERGFFKDLEQELHQHQE
                     RRQQAALTEHLSRMETQPVLTDLPLLPAVPMAGDCSSTATDQPGKESAPKATSSTQTA
                     STTKKQVSKNQKSSVQARKGALAATTSKTSQAATPSMTKMTNKKSTK"
     exon            288..393
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            394..502
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            503..549
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            550..659
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            660..729
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            730..875
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            876..1298
                     /gene="Lrrc46"
                     /gene_synonym="1700006D24Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgagacctc aaggaacggt tctttctatt ccttctggtc ctttcagttt aaggccagta
       61 aagccacgct acacacctct aactccagat ccttcgttcc catttactcc tattttccac
      121 cgcaccccca ataattctca gaaccccctg cccttgtctc ctcagtcttc cctccaacct
      181 gggttcaacc agcccaaccg tctaagcttc tctgctcgcc ttcgtccatc tacctgcctc
      241 aagcagccgc tgtttatttt agatcatgcc aggagacgag caggaagcta agaaagctgc
      301 ccagagaacc gaggaaggtg tccacattac tgaagccctt atcaccaagc ggaacctgac
      361 cttccctgga gatgaagacc tgtcagaaaa gatgtttcac actctcggtg aactggagac
      421 tgtccgcctg gacggggaag ggattacttg tatcgggaat ttagagaaac tccggaatat
      481 tcacagcctc tacctgcaat cgaataagat ccagcgcatt gagaacttgg catgcatcac
      541 ctccctgcgc ttcctgtctt tggcaagaaa ccaaatcagg catgtggaaa acctccttga
      601 cctccagtac ctccagtttc tggacctgtc tgagaacctg atagaaacgc tgaagctaga
      661 tgagctccct gagagccttc tcatcctcaa cctgtgtgga aatccctgca ccaaccagga
      721 aggctacagg aagatggtga taggagccct gccactgctc ttggacctgg acaagcagcc
      781 tatcctggag cggtggacct cagatgagga ggataaatcc tcagatgatg atgatgagtt
      841 tccagagctc aatggcccct tctgcgcaga gcgaggattc ttcaaggact tggagcagga
      901 actgcatcag catcaggaac gcaggcagca ggcagcactg acagagcact tgtcaaggat
      961 ggagacacag cctgtcctca cagacctgcc cctgctgcct gctgtgccca tggctgggga
     1021 ctgcagctct actgccactg accagcctgg gaaggagtca gcccctaaag ctacctcctc
     1081 aactcagact gcctctacta ccaagaaaca ggtttccaag aaccagaaaa gttctgtcca
     1141 ggcaaggaag ggggctctag cagccacaac ctccaagacc tctcaggctg caacccccag
     1201 catgacaaaa atgacaaaca agaaaagcac aaagtagcgc acagcctcta tgcacgcgcc
     1261 acctcctcag gctttgcccc aataaagtgt ctctgggcaa aaaaaaaaaa aaaaaaaaaa
     1321 aaaaaaaaaa aaaaaaaa
//
