LOCUS       NM_153545               2476 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus leucine rich repeat containing 45 (Lrrc45), mRNA.
ACCESSION   NM_153545
VERSION     NM_153545.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2476)
  AUTHORS   Ho,K.H., Candat,A., Scarpetta,V., Faucourt,M., Weill,S., Salio,C.,
            D'Este,E., Meschkat,M., Wurm,C.A., Kneussel,M., Janke,C.,
            Magiera,M.M., Genovesio,A., Meunier,A., Sassoe-Pognetto,M.,
            Brill,M.S., Spassky,N. and Patrizi,A.
  TITLE     Choroid plexuses carry nodal-like cilia that undergo axoneme
            regression from early adult stage
  JOURNAL   Dev Cell 58 (23), 2641-2651 (2023)
   PUBMED   37890489
REFERENCE   2  (bases 1 to 2476)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK153361.1 and CN539620.1.
            
            On Nov 11, 2009 this sequence version replaced NM_153545.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC023296.1, AK153361.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2458              AK153361.1         2-2459
            2459-2476           CN539620.1         709-726
FEATURES             Location/Qualifiers
     source          1..2476
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 84.45 cM"
     gene            1..2476
                     /gene="Lrrc45"
                     /note="leucine rich repeat containing 45"
                     /db_xref="GeneID:217366"
                     /db_xref="MGI:MGI:2387183"
     exon            1..101
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            102..357
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..2150
                     /gene="Lrrc45"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 45"
                     /protein_id="NP_705773.2"
                     /db_xref="CCDS:CCDS25753.1"
                     /db_xref="GeneID:217366"
                     /db_xref="MGI:MGI:2387183"
                     /translation="MEEFRRSYNRLCEESGAEPQEAVLQQLHQLPKGGLDLTTQSLTV
                     ETCRALGKLLHKETLLKELVLSDCMLSEEGSTLLFQGLCANTSVQHLDLKGNNLRATG
                     AEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQISHKG
                     AEELALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPSNRTLWKLDLAGNNIPGDILR
                     AVEQAMDHNQDRLTAFRENQARTKILSKEVQHLQEEKSKQFLDLMETIDKQREEMARD
                     SRASAVRVGQLQEALNERQSIINALKAKLQMTEAALALSEQKVRDLGELLVAGDQERQ
                     SLSQRHEKERKLERQEAADRESKLLRDLSAASEKNLLLRSQVDELERKARSQQEQLFL
                     TKQELTNTSAELKIRAIQAEERLDVEKRRAKQNMEDLEKLHSKEVDHMTRHLEESERA
                     MQERVQRLEALRLSLEEELSRMKAAVLSERGQAEEELIKARNQARLEEQHRLAHLEEK
                     IRLLAQARDEAQGTCVQQKQMVAESQARVSQLNLQMEGQQRRLEELQQELINKDQEKV
                     AEVARVRVELQEQMGRMQADLVAQEALREKVAALERQMKVIGSEHREALLDRESENAS
                     LREKLRLKEAEISRIRDEEAQRASFLQNAVLAYVQGSPLRALSPPK"
     exon            358..419
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            420..490
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            491..669
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            670..798
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            799..911
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            912..970
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1048
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1184
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1262
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1374
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1445
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1538
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1631
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1805
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1953
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     exon            1954..2464
                     /gene="Lrrc45"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2436..2441
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc45"
                     /note="hexamer: AATACA"
     polyA_site      2464
                     /gene="Lrrc45"
                     /note="major polyA site"
ORIGIN      
        1 actcttcctg gatactgagg cgcgaggaac cgcgtcctgc cacaccagcg acccgaggct
       61 acgtcgcgag ggcgggctgg gggccacagg gccagactag ggggcatgct tgcgaggctc
      121 cgtcagcatt cggggacatg gaggagttcc ggcgctccta caaccgcctc tgcgaggaga
      181 gtggggctga gccccaggag gctgttctgc agcaactgca ccagcttccg aagggcggac
      241 tggacctgac tactcagagc ctgacggtgg agacctgcag ggccctcggc aagctgctgc
      301 ataaggagac gctgttgaag gagcttgtcc tcagcgactg catgctgagt gaagaagggt
      361 ccacactgct gttccaaggg ctgtgtgcca acaccagtgt gcagcatctg gatctaaagg
      421 gcaacaacct ccgagctaca ggagctgagg ctctgggaaa gctccttcga cagaacaagt
      481 ctattcagag cctcacgctg gagtggaaca accttggcac gtgggaagat gcctttgcca
      541 ccttctgtgg gggtctggca gccaatagtg ccctgcggca gctggacctc cgaaacaacc
      601 agatcagtca caagggagca gaggaactgg ccctggccct gaagggcaac accaccctcc
      661 aacagctgga cctgcgctgg aataacattg gcctcctggg gggccgggct ctggtgaact
      721 gtctccccag caacagaacc ctgtggaagc tggacctggc tgggaacaac atccctggtg
      781 acatcctgag agccgtggag caagccatgg accacaacca ggaccgactc actgcctttc
      841 gggagaacca agcacgcacc aagatcctta gcaaggaagt tcaacacctc caggaggaga
      901 agtccaagca gtttctggat ttgatggaga caatagacaa gcaacgagaa gagatggcca
      961 gagatagccg ggcatcagca gtacgggttg ggcagcttca ggaagccctc aacgagaggc
     1021 agtccatcat caatgctctc aaagccaaac tgcagatgac agaggctgct ctggctctgt
     1081 cagaacagaa ggtccgggac ctgggggaac tgctggtcgc cggagaccag gaacggcaga
     1141 gcctgtccca aagacatgag aaggaacgca agctggagcg gcaggaagct gcagatcggg
     1201 agtccaagtt actcagggac ctgtctgctg ccagcgaaaa gaacctgctg cttagaagcc
     1261 aggtggatga gttggagcgg aaggcgaggt cacagcagga gcagctgttt ctgaccaagc
     1321 aggagctgac taacacgtcg gccgagttga agatccgtgc tattcaggct gaggagcgct
     1381 tggatgtgga gaagaggaga gccaaacaga acatggaaga cttggaaaag ctacactcca
     1441 aggaggtgga tcatatgact cgtcacctgg aggagagtga gagggccatg caggagaggg
     1501 ttcagagact agaggccctg cggctgtctc tggaggagga gctgagccgc atgaaggctg
     1561 cagtgctcag cgagcgtggc caagctgagg aggagctcat caaagccagg aaccaggccc
     1621 gcttggagga gcaacaccgc cttgctcatc tggaggaaaa gatccggctg ttggcacagg
     1681 caagggacga ggctcagggc acctgcgtgc agcagaagca gatggtagcc gagtcccagg
     1741 cacgggtcag ccagctgaac ctgcagatgg aggggcagca gcggcgtctg gaggagctgc
     1801 aacaggagct gatcaacaaa gaccaagaaa aagtggccga agtggccagg gtcagagtag
     1861 agctgcagga acagatgggc cgtatgcagg ctgacctggt ggcccaggag gcgctgagag
     1921 agaaggtggc agccctggag cgtcaaatga aagtgatcgg gagtgaacac cgggaggcgc
     1981 tgttggacag agagagtgag aacgcatctc tccgagagaa gctgcggctc aaagaggcag
     2041 aaatctcccg tatccgggac gaagaggccc agagggcaag cttcctgcaa aacgctgtct
     2101 tggcttacgt gcaggggtcc cctctgagag ccttgagtcc ccctaaatga agggaagcgg
     2161 gagaaccgaa gcgcccagcg agggtagaaa tgctgcatcc cattctcaag ggcaggcccg
     2221 gggtccaaaa agcatcagct gcagttgcag ggcagggttc tgtcaacatc ggtgctcagc
     2281 ggcacacctg ccggtccaag ggacttcatc cacagttcac cgttagcata ggcgcgatga
     2341 agcatacagg atcgcgctca gacaacccgg tcccagaacc acaaacagga caggacagcg
     2401 gtgggaggaa gcagactccc caatggcagg gtggaaatac agaacttttg tacttggtga
     2461 taaaaaaaaa aaaaaa
//
