LOCUS       NM_001033461            2046 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus leucine rich repeat containing 43 (Lrrc43), transcript
            variant 1, mRNA.
ACCESSION   NM_001033461 XM_355723 XM_915443
VERSION     NM_001033461.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2046)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133051.1 and DV646947.1.
            
            On Jan 31, 2014 this sequence version replaced NM_001033461.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133051.1, SRR5189685.190324.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2045              AK133051.1         2-2046
            2046-2046           DV646947.1         85-85               c
FEATURES             Location/Qualifiers
     source          1..2046
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 63.01 cM"
     gene            1..2046
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /note="leucine rich repeat containing 43"
                     /db_xref="GeneID:381741"
                     /db_xref="MGI:MGI:2685907"
     exon            1..149
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     CDS             6..2009
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /note="isoform 1 is encoded by transcript variant 1;
                     leucine-rich repeat-containing protein 43"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 43
                     isoform 1"
                     /protein_id="NP_001028633.1"
                     /db_xref="CCDS:CCDS19664.1"
                     /db_xref="GeneID:381741"
                     /db_xref="MGI:MGI:2685907"
                     /translation="METSESSTSDYRQTEGEGEGVPGTLSTAVCEHLRKLCLREFPCG
                     IGSWNKSRFLPQKCRVWRELVPKEEETLVPEEETVEALLGLVRSNHSPWAMLKDASAE
                     DRFLRELAIQNPLMIKDTFFYSYFRSLRVVNKGVSLVDKDLLKFLKLEELVLSANKIE
                     EIDANNLPPTLKVLELYGNLIASMECLCSAPPPRLQHLGLGHNKLLGPLESLYVTSHN
                     WPQLVSLDLGFNNLTDLQNMILGLSTLRHLRLLVLQGNPLSLVPYYRGFTIDSLAHLC
                     VLDDITVSPNEKHQFRGLNIHGDLLAREAQFVVTIGNVRGVLDSSILDPEPGPDGPFI
                     SYSYYVTYDFVEDEDMERNVSGLVEATHHDSVLDEIDKHFSGTDEEDQQEDPLDGRHR
                     HRGRQRFHPGSTEEMSKELSEFIAKEMSQMAEGSVESGITEVDWSETSISIHSAPLPQ
                     SIDSSEELAKLRPKIDIQLCPSPGTVLFNTVHKPWSDVIPCTYEMKHTLKELIRVKAF
                     LLAGTTVSIVEEKILSWPVVPTPVESPLPAKKGKDNNKKKEPAKDKVHKKKKEPPREL
                     RQDPPVLTVLGSGLVYLEPLLAGEAVVSTVCNFGVVRTLETDRLTHARDSKKVKKSLK
                     KDRSKTVPPTMESGYQPEPLSVEVQIQLHQYRSVEEAFLSLID"
     exon            150..410
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            411..521
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            522..661
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            662..900
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1112
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1426
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1568
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1661
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1847
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..1881
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2046
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2017..2022
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /note="hexamer: AATAAA"
     polyA_site      2046
                     /gene="Lrrc43"
                     /gene_synonym="Gm1061"
                     /note="major polyA site"
ORIGIN      
        1 acagcatgga gaccagcgag tccagcacta gcgactacag acagaccgag ggcgagggcg
       61 agggtgtacc ggggaccttg agcacggctg tgtgtgagca cctgcggaag ttgtgtctgc
      121 gcgaattccc gtgtggcatc gggagctgga ataagtcacg ctttcttcct caaaaatgtc
      181 gagtctggag ggaattggta cccaaggagg aggagacact ggttcccgag gaggagactg
      241 tggaggccct gctgggcctg gtgcgcagca accactctcc ttgggctatg ctgaaggatg
      301 ccagcgcgga ggaccgtttc ctgagggagc tggccatcca gaatccactg atgatcaaag
      361 acactttctt ctactcctac ttccggtccc tgcgggtggt gaacaagggg gtgagtctgg
      421 tggataaaga cctcttgaaa tttctaaagc tggaggagtt ggtcctgagt gccaataaaa
      481 ttgaggaaat cgatgccaac aatctgcccc cgacattgaa ggtgctggag ctctatggca
      541 atttgatcgc cagcatggag tgtctgtgct cagccccgcc cccaaggctg cagcacctgg
      601 ggctaggcca caacaaattg ctgggccctt tggagagtct gtatgtcacc tcccacaact
      661 ggccccaact cgtctccctg gacctgggct tcaacaactt gacggacctg cagaacatga
      721 tcttgggact cagtaccctg aggcacctga ggctcctagt actgcagggg aacccactat
      781 ctctggtgcc ttactaccgt ggctttacca tagacagcct ggcacatctt tgtgtgctgg
      841 acgacatcac cgtgtctccc aatgagaagc accagttccg gggactcaac attcacggtg
      901 accttttggc acgtgaggcc cagtttgtgg tgacgattgg aaatgtcaga ggggttctgg
      961 acagctctat cttggacccg gagccgggac ctgacggccc tttcattagc tacagctatt
     1021 atgtgaccta tgactttgtg gaagatgagg acatggaaag aaatgttagt gggctagtag
     1081 aggcaacaca tcatgacagc gttctggatg agatcgacaa gcatttctct ggcaccgatg
     1141 aggaggacca acaggaggat cccttagacg gccgccaccg ccacagaggc cgtcagaggt
     1201 ttcacccagg ctcgacggag gagatgtcca aggagctgtc tgagttcata gcgaaggaga
     1261 tgagtcagat ggcagaaggc tcggttgaat ctgggataac agaggtcgac tggtcggaga
     1321 cgagcatttc catccactct gcgcccctgc cacagtcaat cgactcttct gaagagctgg
     1381 ccaagctgcg gccaaagata gacatccagc tctgtccatc cccagggaca gtcctcttca
     1441 acacggtgca caagccctgg tcagatgtta ttccctgcac ctatgagatg aagcacaccc
     1501 tcaaggagct gatccgggtc aaggccttcc tgctggctgg gactactgtg agcatcgtag
     1561 aggagaaaat cctctcctgg cctgtggtac ccactcccgt tgagagtccc ttgcctgcca
     1621 agaaggggaa agacaacaat aaaaagaaag agcctgctaa ggataaggtc cacaagaaga
     1681 aaaaggagcc gcccagggag ctgcggcagg acccccctgt gctgacggtg ttgggcagcg
     1741 ggctggtgta cctggagccc ttgctggccg gggaggcagt ggtatccact gtgtgtaatt
     1801 tcggggtggt ccgaaccctg gagacagaca ggctcacaca tgccagggat tcaaagaagg
     1861 taaagaaatc tctcaagaaa gataggtcga aaacggtgcc tccaaccatg gaaagcgggt
     1921 accagccaga gccactgtcg gtggaggtcc agatccagct gcaccagtac cgctcggtgg
     1981 aggaagcatt ccttagcttg attgactagc agggagaata aaggctgctc tgcagccgga
     2041 gcttga
//
