LOCUS       NM_175124               2978 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus leucine rich repeat containing 28 (Lrrc28), transcript
            variant 1, mRNA.
ACCESSION   NM_175124
VERSION     NM_175124.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2978)
  AUTHORS   Ikegami,K., Saigoh,K., Fujioka,A., Nagano,M., Kitajima,K., Sato,C.,
            Masubuchi,S., Kusunoki,S. and Shigeyoshi,Y.
  TITLE     Effect of expression alteration in flanking genes on phenotypes of
            St8sia2-deficient mice
  JOURNAL   Sci Rep 9 (1), 13634 (2019)
   PUBMED   31541165
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI663251.1 and BC086694.1.
            
            On Jul 30, 2009 this sequence version replaced NM_175124.4.
            
            Transcript Variant: This variant (1) is the longest transcript and
            encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077270.1, AK159417.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-439               AI663251.1         1-439
            440-2978            BC086694.1         331-2869
FEATURES             Location/Qualifiers
     source          1..2978
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 37.05 cM"
     gene            1..2978
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /note="leucine rich repeat containing 28"
                     /db_xref="GeneID:67867"
                     /db_xref="MGI:MGI:1915689"
     exon            1..59
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            60..296
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1232
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     leucine-rich repeat-containing protein 28"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 28
                     isoform 1"
                     /protein_id="NP_780333.3"
                     /db_xref="CCDS:CCDS21351.1"
                     /db_xref="GeneID:67867"
                     /db_xref="MGI:MGI:1915689"
                     /translation="MASEICKTISVARLEKHKNLFLNYRNLHHFPLELLKDEGLQHLE
                     RLYMKRNSLTTLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEI
                     VCPEIGGLRALRHLRLANNQLQFLPPEVGDLKELQTLDISSNRLLALPERLHLCLSLQ
                     YLTVDRNRLCCVPRHLCQLPSLNELSMAGNHLASLPIDLGRSRELQYVYVDNNIQLKG
                     LPSYLYNKVIGCNGCGIPIQLSEVRLLTFSSGQLTVFLPAEVKTIGTEKDHVLPLQEL
                     TMRSLYRTYHGLWKDLNFLSPISLPRSLLELLHCPLGHCHLCSEPMFTFVYPKIFPLR
                     ETPMAGLHQRRTSIGFVAYCCSTQCLRTFNLLC"
     exon            297..337
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            338..375
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            376..513
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            514..720
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            721..823
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            824..999
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1159
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..2928
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1443..1448
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /note="hexamer: AATACA"
     polyA_site      1464
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /note="major polyA site"
     regulatory      2908..2913
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2928
                     /gene="Lrrc28"
                     /gene_synonym="1300004K21Rik; 2210012C09Rik;
                     2310058O11Rik"
                     /note="major polyA site"
ORIGIN      
        1 tttttagact gcctaccagc gcagcctgag ccgctgagtg ccggtcagcg ggcgccgaga
       61 attggaccaa atggaccagt tttgacaaga tgtagtgcga cagcacttcc ggttggacat
      121 gttcagtcat ggcatccgaa atctgtaaga cgatctctgt ggccaggctt gaaaagcaca
      181 agaatttgtt cttaaattac aggaatctgc accattttcc actggagttg ctgaaggatg
      241 aggggctgca gcacctggag aggctctata tgaaaaggaa ctccctcaca accttgccag
      301 aaaaccttgc tcagaagctt ccaaaccttg tggaactgta ccttcactca aataacatag
      361 ttgtggttcc agaagccatc gggtccctcg tgaaactcca gtgtctggat ctcagtgaca
      421 atgccttaga gatcgtttgc ccagaaatcg gtggtctgag agcgttgcgt catcttcgat
      481 tagctaataa ccagctacag ttcctacctc cagaggttgg cgatttgaag gagctgcaga
      541 cactagacat ttctagcaat cgcttgctag ctttacccga gaggcttcac ctgtgccttt
      601 ctctgcagta cctcactgtg gaccgcaatc ggctatgctg tgtgccgcgc catctctgcc
      661 agctgcccag cctcaatgag ctctccatgg ctggaaacca tcttgcatct ttgcccattg
      721 atttaggtcg ctcccgagaa ctgcagtacg tgtatgtgga taacaacatc cagctgaagg
      781 gcctgccctc atacctctac aacaaagtca tcggctgcaa cggctgtggc atccccatcc
      841 aattgtcaga ggtgaggctg ctgacatttt catctgggca gctgacagtc ttcctcccag
      901 cagaggtgaa gacaataggc acagagaagg atcatgtcct gcctctgcaa gaactgacca
      961 tgcggagtct ctaccgcacc taccacgggc tttggaaaga tctgaacttt ttgtctccaa
     1021 tctcattacc cagaagtctc ctggagctgc tgcactgccc cctggggcac tgtcacctgt
     1081 gtagtgagcc catgtttacc ttcgtctatc ctaagatctt ccccttgaga gagacgccga
     1141 tggcaggcct gcaccagagg aggacaagta ttggcttcgt ggcttactgc tgctccaccc
     1201 agtgtctgcg gacttttaac ctgctgtgtt gataaacact cgagagcctt aggagcactg
     1261 ccagctcagc cactgcgact gccttccatc gccagtgtgt gcggccaggc caggagagtc
     1321 cagccaggca ggacagaccc ttccatcctg cctgccctgt cctgaggagg gccgtgctga
     1381 actctgggaa tgtcctgatt gggcttcaca actaaaaggc cttcgctttt ccctcaagtc
     1441 ggaatacatc ctcccccaaa tgaaggacgt gttgtcttct gtgtttttct ttgtatgtga
     1501 gtgtgtctca tatataaact tagtcaaatg agcttcccca catctaattt aaagcgagct
     1561 gcagttccct gaagaactct taatttgata atagaaccaa attaactgtt ggatgacata
     1621 cgtttggtga tgatcctgcc ttcccccaga ggatgatttc ccctggagat tattcttagg
     1681 agcttctcca ttggaaactt gtcactttct agagtctctg caacgcctat ggcctcagca
     1741 gccagcatag cagggcaggg tgcccgggct ggagcagcta ggctcctgca gaggcacagc
     1801 tggctccaga gcacacgccc tctggaaact tcctgtctta tttctaagtt ttgcaaccta
     1861 ggaagacatt ttttgagagg gatttaaaaa caaaaatgta gacacaaatt aaatatactt
     1921 ttgttctaaa ctactataga aaaagaagtt ttgaattttt tttttttttt ttttgctaag
     1981 attttcctat aattgggaag tttgaggcat ctgatgctct gctgtggatg gggcttagtg
     2041 gtatttaccc ggtacatgaa attgccttca ttttcctctg acttctccct agggaaacag
     2101 aaggaatgaa cgggtccaca tcccaccttt gcaaaaatcc catgagcttt cccttgccag
     2161 agagatgagc tctctggggg gacagctgat tggctcttcc tctgaaagga tgccaccata
     2221 atctgtttta ctttcaggtg ttcgttgggc tgctttgggg ggggggtaaa agttctctgt
     2281 ttactggtat gatttatgta agacaagact gaaaggggaa tcaagaaggc ttgcttggtg
     2341 ggaaagctat ttcccaaaac tttggttggt gacattttgt tagccagcct gactgtaatt
     2401 ctaggctcta acagtgccaa aaatcctaca tagttactga caagtgtgtg atctctttgc
     2461 agtcacacca cctgctgcct gaaaagcaga ctcttccaag taatggcaga ggcagaaagc
     2521 ggccatgcat gccatgtgtg gccactgtcc ctacttcctc ccgtcccttt cacaacttgc
     2581 tctgttcagc cttaatattt caaaggccta cagtataata ggagctgagc gtctggatca
     2641 agtgtatctc ttctttcatc ctttcggaag aatggaagtt tcagcacaac cccgacatgt
     2701 atataagctg aaggcaggaa aatgtggcct gacacttcac atccgtgctt gacttaattg
     2761 aacgacaggg aaacacaggg ctgcatctgt gttttgccct cgaccatctt atgtcttaag
     2821 tggagctatg aaatgtcacc ctgatactca ggaattctca ttgagagaag gtgtgggata
     2881 cttttgttct aacttgttta aattcttaat aaaggtgttt acactccaaa aaaaaaaaaa
     2941 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
