LOCUS       NM_027164               2329 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus leucine rich repeat containing 27 (Lrrc27), transcript
            variant 1, mRNA.
ACCESSION   NM_027164 XM_133916
VERSION     NM_027164.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2329)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2329)
  AUTHORS   Zambrowicz,B.P., Abuin,A., Ramirez-Solis,R., Richter,L.J.,
            Piggott,J., BeltrandelRio,H., Buxton,E.C., Edwards,J., Finch,R.A.,
            Friddle,C.J., Gupta,A., Hansen,G., Hu,Y., Huang,W., Jaing,C.,
            Key,B.W. Jr., Kipp,P., Kohlhauff,B., Ma,Z.Q., Markesich,D.,
            Payne,R., Potter,D.G., Qian,N., Shaw,J., Schrick,J., Shi,Z.Z.,
            Sparks,M.J., Van Sligtenhorst,I., Vogel,P., Walke,W., Xu,N.,
            Zhu,Q., Person,C. and Sands,A.T.
  TITLE     Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap
            screen to identify potential targets for therapeutic intervention
  JOURNAL   Proc Natl Acad Sci U S A 100 (24), 14109-14114 (2003)
   PUBMED   14610273
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC050816.1.
            
            On Mar 10, 2005 this sequence version replaced XM_133916.5.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC050816.1, SRR5189685.113278.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..2329
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 84.3 cM"
     gene            1..2329
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /note="leucine rich repeat containing 27"
                     /db_xref="GeneID:76612"
                     /db_xref="MGI:MGI:1923862"
     exon            1..280
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            281..565
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             329..1900
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     leucine-rich repeat-containing protein 27"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 27
                     isoform a"
                     /protein_id="NP_081440.1"
                     /db_xref="CCDS:CCDS21953.1"
                     /db_xref="GeneID:76612"
                     /db_xref="MGI:MGI:1923862"
                     /translation="MEDTSPQAVAEKAAKDPKAAKDLKDDAAAATKSFPDHFSREGDD
                     QMDFEGVIFSSSPVLDLSQRGLRHLGKFFKIPNLQQLHLQRNLLREIPEDFFQLLPNL
                     TWLDLRYNKIKVLPSGIGSHKHLKTLLLERNPIKMLPVELGQVTTLTALNLRHCPLEF
                     PPRLIVQKGLVAILTFLRICSVEKAFPGDELLPEVSAPKMGSNDLQYPVLPLPRKGSP
                     SENSLNDPDQEKEKADFFPPMERLDLSELRKSNAASEIWPSKEEIRRFWKLRQEIVEN
                     EQVEIQEKKLLAVELPPNLKAALNVKEKKHRKPWPAVRKRSTSFKGILPNLPSGYQNT
                     VHANRMEDTHKAALQELQEKETVLEQRRRDKRALQEWREQTQHMRTRRELSKLQPPHS
                     NMMASKIPFATDLTDYEKMPVSPFGKVKPSGEGTAQRPIEISASPLAELEDKIKRHTQ
                     QIRTRSFLGTNPMQDIKTANQDLETTKKLQEELRKLKVEMTLNKDHPFPSFTGNLSLH
                     PPASQPQNIFFNTKS"
     exon            566..696
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            697..755
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            756..908
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1269
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1416
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1510
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1629
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1753
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..2107
                     /gene="Lrrc27"
                     /gene_synonym="1700071K18Rik; 2310044E02Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaggcgcgg agggcagcgg tcagttccag aggcctgagg cccgagggtc catggccctg
       61 gaagacggtc tggtcagcag aagcatcact cgacctcctt cgggtcccca agccctcccc
      121 gaatccacca gcccatcctc tcgaagtttc tttctggcct tgtcgcccac ctccagcata
      181 agaggcggta agcgcacgcg caccgaagct atcccaagcc agacctgcga cttgatgcct
      241 tccggcctcc gtaccgcagc agcgtctcca tggcgacctg gtgactccat accaagaagg
      301 atgagcagtg gccactggag cgcatcacat ggaggacacc agcccccaag cagtggccga
      361 gaaggctgct aaagacccca aggctgctaa agatctcaag gatgatgctg ctgccgccac
      421 caagagcttc cccgatcact tttccagaga gggtgatgat caaatggact ttgaaggggt
      481 catcttttct tcctcaccag ttttagacct gagtcaaaga ggcctgcgcc atttgggaaa
      541 gttctttaaa attcccaacc tccaacaatt acacctgcag aggaatttgc tcagggagat
      601 tccggaggat ttcttccaac tgctgcccaa cctgacatgg ctggacctcc gttacaacaa
      661 aatcaaggtt cttccatctg ggattggctc tcacaaacat ttgaaaactt tgcttctaga
      721 acgaaatcct atcaaaatgt tacccgttga gctggggcag gtcactacac tgacagcact
      781 gaacctgaga cactgccctc tggaatttcc tcctcgcctg attgtgcaga aaggcttggt
      841 agccatcctc accttcctac gcatctgctc agtggagaag gccttccctg gagatgagtt
      901 gcttccagaa gtctcagcac ctaagatggg cagcaatgac cttcagtatc ccgtgctccc
      961 tctgccccgt aaaggctcac ctagtgagaa cagccttaat gacccagacc aggagaagga
     1021 gaaggctgac ttcttcccac ctatggaaag gctagacctg agtgagctcc gcaaatccaa
     1081 cgccgcctcc gagatatggc ccagtaagga ggagatcaga cgcttctgga agctgaggca
     1141 ggagattgtg gagaatgagc aggtggagat tcaagagaag aagctcttgg ctgttgagct
     1201 gccgccaaat ctcaaggcag cgctaaacgt caaggagaaa aagcacagga agccatggcc
     1261 cgcagtcagg aagaggtcca cctccttcaa aggcatcttg cccaacctcc cttcagggta
     1321 ccaaaacaca gttcatgcaa acaggatgga agacactcac aaggcggctc ttcaggagct
     1381 ccaagagaag gagacagtgc tggagcaacg gaggagagac aagagagctc tgcaggagtg
     1441 gcgagagcag acccagcaca tgaggaccag gagggaactc agtaaactcc aacctccaca
     1501 tagtaacatg atggcatcga agattccctt tgccacagat ctgacagact atgagaaaat
     1561 gccagtaagt ccatttggga aagtgaagcc cagcggagag gggacagcac aaaggcctat
     1621 agaaataagt gcctcaccat tagcagagct ggaggacaag ataaagcggc acacacagca
     1681 gatccgcact cgaagtttcc tgggtacaaa cccaatgcaa gacattaaga cagccaacca
     1741 ggacctggaa accactaaga aacttcagga ggagttaagg aaactgaaag tggagatgac
     1801 cttgaacaaa gaccatccat ttccatcttt cactggaaac ctttcacttc acccaccagc
     1861 atcacagcct caaaatatat tttttaacac gaaatcctag gaaggcagcg ctgtcagcag
     1921 gagtgacaag taccttccac acgaggagct gctgtccccc atgtgtgtgg ggactggcct
     1981 ggatgacaac tcgcgggtaa ctcgcgggtc ttcagctgcc acacaggcta tggcttttaa
     2041 tagacctgat tccttcctga ggctatagaa ggtttagctg cattaaaagg aagaatgctg
     2101 taagcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2161 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
