LOCUS       NM_153542               2636 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus leucine rich repeat containing 20 (Lrrc20), mRNA.
ACCESSION   NM_153542
VERSION     NM_153542.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2636)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   3  (bases 1 to 2636)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC036304.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036304.1, AK139384.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 32.22 cM"
     gene            1..2636
                     /gene="Lrrc20"
                     /note="leucine rich repeat containing 20"
                     /db_xref="GeneID:216011"
                     /db_xref="MGI:MGI:2387182"
     exon            1..57
                     /gene="Lrrc20"
                     /inference="alignment:Splign:2.1.0"
     exon            58..204
                     /gene="Lrrc20"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..677
                     /gene="Lrrc20"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 20"
                     /protein_id="NP_705770.1"
                     /db_xref="CCDS:CCDS23881.1"
                     /db_xref="GeneID:216011"
                     /db_xref="MGI:MGI:2387182"
                     /translation="MLRKMGEAVARVARKVNETVESGSDTLDLADCKLVSFPICIYKV
                     LRNVSDQIHLITLANNELKSLTSKFMTTFNQLRELRLEGNYLFRLPNEVSSLQHLRAI
                     DLSRNQFQDFPEQLTTLPALETINLEENEIVDVPVEKLAAMPALRVINLRLNPLSADV
                     RVIAPPLIKFDMLMSPEDTRAPPP"
     exon            205..354
                     /gene="Lrrc20"
                     /inference="alignment:Splign:2.1.0"
     exon            355..522
                     /gene="Lrrc20"
                     /inference="alignment:Splign:2.1.0"
     exon            523..2635
                     /gene="Lrrc20"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2318..2323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc20"
                     /note="hexamer: AACAAA"
     polyA_site      2339
                     /gene="Lrrc20"
                     /note="major polyA site"
ORIGIN      
        1 gtcggtcgcc gcgggagcgt gagtgctggg cgctgggctc taggacgcat tgtcgccgca
       61 cagacccccc tttgtgagtc gcagaccggc ctgaaggctg ggagccgaac acccacgtct
      121 gcatgctgag gaagatgggg gaggccgtgg ccagagttgc gaggaaggtc aatgagactg
      181 tggaaagcgg ctcagatacc ctggacctgg ccgactgcaa gcttgtttct ttccccatct
      241 gcatctacaa ggtcctgagg aacgtctctg atcagatcca tctcatcacg ctggctaaca
      301 atgaactcaa gtccctcacc agcaagttca tgaccacctt caatcagctt cgagagctac
      361 gcctggaggg caactacctc tttcgactcc ccaatgaggt cagcagcctg cagcacctca
      421 gggccattga cctgtcccgg aaccagtttc aagacttccc agagcagctg accaccttgc
      481 ctgcactgga gactatcaac ctggaggaga atgagatagt ggatgttccg gtggagaagc
      541 tggctgccat gccagctctg cgagtcatca acctgcgcct caaccccctg agcgccgacg
      601 tgcgtgtgat tgccccaccg ctcatcaagt ttgatatgct catgtctcca gaggatacgc
      661 gggcccctcc gccttaggac acactccttg cgctcaccca gcaagggaca aaggatactg
      721 gcctgccacc ctgagaggag gaaggcccat gggaagccaa gcttggggag cggggtgggt
      781 gggccaggca gcatacagag ggaggggcac agctaagcca gggtgggtag cttagcactg
      841 tagtgagccc tggtgctcca gagggaggag ggaggtgagg ctagagccta ggctcagggc
      901 catcacagct gctgagctga cttggttagg tctcttgctc tctctgagct tggttacttg
      961 agagaaggaa aaattgtggc aagcctttcc tgcctgggac ccctcagagg ttctgtctcc
     1021 acatcgtcgg acgccctcta agctcctgga tgagcctcgc tgggcatttg gtggacctta
     1081 tgatttgaag cctggtttct agtgtgagaa tcaatcacca ttctgagaga ccacctccac
     1141 ctatttatcg acttctgaac acagtggcgc ccatcatggt gccatgtcct ggccatcagt
     1201 gtccctggac tggtcagagc ctgagcccag acattggttg ggccttgtgg caggagcatt
     1261 tatgaagaac cccacagaca tctggccagc tcattcttcc ttgtcctgag acattgtgtg
     1321 aaggactttc tacacactcc gttctatccc tccctgagaa tggcctggcc tggtcagaca
     1381 ttacccacag ggccatagga gaggtggccc agagaagaca aagccacctg catgtgataa
     1441 ctgggatcca aggtccttag gtgacctcct tcaccctgac cttcctcttg tgacctccct
     1501 ctgatgacaa cctggttgcc tcaccctggc tcagtaccac caacctcaag gctgtcacca
     1561 taatgacctg ccatcttgat aacctttgcc tgtggcctaa ggggccacca actgtcccag
     1621 tatgcccaga actgtggcat ttcccaggag gcagctgggc ccttgccccc tgctaaggcc
     1681 tgtgcttggg gatatccctg acccccctca atcttcatgt gtctacctcc tcacctgaac
     1741 agcaggccta tcagctgccc ccggtcctgg ctggtctaca cctttgtata ggtctgtgga
     1801 ggccccagga cacaggcagg gctaggccac tttgtctcca acattttgcc tttagcaccc
     1861 aaactgttgt tcagcggaaa cccaccacgg agtttgtcca ggtccctgtc tcttcacaat
     1921 gttcctggct ctcagtaggg ttgccatggg agcactgctg gtatcatggc tgtgtatcct
     1981 aaaagaaacc ttgcctattc cgctttcatc cctaggccag ccagccagat gaggaggtag
     2041 acacagggcc caagcaaggg ctgggtgcag cctgaactgg aatggctcct ccagcaccac
     2101 ccccatcccc cgtgtctctg agttgggggt tttaccttgt aaaggaagag ggatgcaaga
     2161 gcctggcaac tctaagtgtt gataggctca cagcagcttg ctaaaaatac agcctccagg
     2221 ggtgtatacc tgagatccgg cacatggtgg gcctgagacc gtaggattgt ggaggtgagg
     2281 tcagcctatg ctgtataatg agagcctatc tcagtgcaac aaaagcagac aaagtaaaag
     2341 aagaagagtg tcagacatgg tgatggtccc ttataatccc agatctccga aagtagaagc
     2401 aggaaggtca ggagttctag gccaaccttg gcctagacta aataatcccg ggggctggag
     2461 agatggctcc gaggttaaga gtactgactg ttcttccaga ggtcctgagt tcaaatccca
     2521 gcaatcacat ggtggctcac aaccatctgt aatgggggat ccgatgcctt cttctggtgt
     2581 gtctgaagac agtgacagtg tatctatata catgaaatta aaaaaaaaaa aaaaaa
//
