LOCUS       NM_001146021            1249 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus leucine rich repeat containing 18 (Lrrc18), transcript
            variant 2, mRNA.
ACCESSION   NM_001146021
VERSION     NM_001146021.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Nie,D.S., Xiang,Y., Wang,J., Deng,Y., Tan,X.J., Liang,Y.H. and
            Lu,G.X.
  TITLE     Identification of a novel testis-specific gene mtLR1, which is
            expressed at specific stages of mouse spermatogenesis
  JOURNAL   Biochem Biophys Res Commun 328 (4), 1010-1018 (2005)
   PUBMED   15707978
  REMARK    GeneRIF: The time-dependent expression pattern of mtLR1 in
            postnatal mouse testes suggested that mtLR1 gene might be involved
            in the regulation of spermatogenesis and sperm maturation.
REFERENCE   2  (bases 1 to 1249)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK015365.1, BC048444.1, AK005666.1, AK006063.1 and BB017856.1.
            
            Transcript Variant: This variant (2) uses a different segment for
            its 3' coding region and UTR, compared to variant 1. The resulting
            protein (isoform 2) lacks N-terminal sequence when it is compared
            to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006063.1, BC048444.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                AK015365.1         5-20
            17-615              BC048444.1         2-600
            616-1045            AK005666.1         556-985
            1046-1246           AK006063.1         983-1183
            1247-1249           BB017856.1         227-229
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 19.61 cM"
     gene            1..1249
                     /gene="Lrrc18"
                     /gene_synonym="4930442L21Rik; MTLR1"
                     /note="leucine rich repeat containing 18"
                     /db_xref="GeneID:67580"
                     /db_xref="MGI:MGI:1914830"
     exon            1..160
                     /gene="Lrrc18"
                     /gene_synonym="4930442L21Rik; MTLR1"
                     /inference="alignment:Splign:2.1.0"
     exon            161..258
                     /gene="Lrrc18"
                     /gene_synonym="4930442L21Rik; MTLR1"
                     /inference="alignment:Splign:2.1.0"
     exon            259..1249
                     /gene="Lrrc18"
                     /gene_synonym="4930442L21Rik; MTLR1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1229..1234
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lrrc18"
                     /gene_synonym="4930442L21Rik; MTLR1"
                     /note="hexamer: CATAAA"
     polyA_site      1249
                     /gene="Lrrc18"
                     /gene_synonym="4930442L21Rik; MTLR1"
                     /note="major polyA site"
ORIGIN      
        1 tttgtgaggt ttctctagag cggaatggag ctggggagag caagggtctc ctctcccttc
       61 ctctagatca tcggctatga gctccaagga agacccatcc tttctgttac caccagagaa
      121 agacgccatt accaaatggt ggtaagacat ccaaccaaaa gctggcgtca agattatgct
      181 gattaactcc aagtcccaag actcttgttg gctggaaacc aagtttcaca gcaaaggagc
      241 ttaaggacaa aaacacagag cttaccatct agcagtttca tgtgacttct tcctcaaaca
      301 catcaccatc ggctcgggaa ggacatcctt caaatacact cccatacttc gagaccatgg
      361 ccaaaggagg gaaaggcccc aagggcaaaa agatcaccct taatgtggca aagaactgca
      421 tcaaaatcac atttgatggg agaaaacgcc ttgacctgag caagatgggt atcaccacct
      481 tccccaagtg tatcttgcgg ctcagtgata tagatgagct agatcttagc cggaatatga
      541 tcagaaaaat tcccgactcc atcgccaagt tccagaacct gcgatggctc gacctgcaca
      601 gtaactatat tgacaagctc cctgaatcca ttggccagat gacctccttg ctcttcctca
      661 atgtgagcaa caacaggctg accaccaacg ggcttcctgt ggagctgaac caactcaaga
      721 acatccgcac cgtgaatctg ggccttaacc acctggacag cgtgcccacc acactggggg
      781 ccctgaagga gctccatgag gtggggctgc atgacaatct gctgactacc atccccgcca
      841 gcatcgccaa gctccccaag ctgaagaagc tcaacataaa gaggaacccc ttcccaaatg
      901 cagatgaatc ggagatgttc gtagactcca tcaaaaggct agaaaacctc tatctggtgg
      961 aagagaagga tatgtgttca tcctgtctgc agagatgcca acaggccagg gacaagttga
     1021 ataaaatcaa gagcatggcc ccctctgcac cgagaaaggc cctcttttcc aatttggttt
     1081 cacccaactc aacagccaag gatgcccagg aagaatggag gtgacctggg accctgaggc
     1141 aggagggaga aaggagggaa gacgagacag taggctgtac ccaaaggaga gggctcttgt
     1201 attactgtgg gagcctttcc acccaagcca taaaacacca ttccctacc
//
