LOCUS       NM_028977               2204 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus leucine rich repeat containing 17 (Lrrc17), mRNA.
ACCESSION   NM_028977 XM_904948 XM_919092
VERSION     NM_028977.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2204)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2204)
  AUTHORS   Decourtye,L., McCallum-Loudeac,J.A., Zellhuber-McMillan,S.,
            Young,E., Sircombe,K.J. and Wilson,M.J.
  TITLE     Characterization of a novel Lbx1 mouse loss of function strain
  JOURNAL   Differentiation 123, 30-41 (2022)
   PUBMED   34906895
REFERENCE   3  (bases 1 to 2204)
  AUTHORS   Liu,F., Yuan,Y., Bai,L., Yuan,L., Li,L., Liu,J., Chen,Y., Lu,Y.,
            Cheng,J. and Zhang,J.
  TITLE     LRRc17 controls BMSC senescence via mitophagy and inhibits the
            therapeutic effect of BMSCs on ovariectomy-induced bone loss
  JOURNAL   Redox Biol 43, 101963 (2021)
   PUBMED   33865167
  REMARK    GeneRIF: LRRc17 controls BMSC senescence via mitophagy and inhibits
            the therapeutic effect of BMSCs on ovariectomy-induced bone loss.
REFERENCE   4  (bases 1 to 2204)
  AUTHORS   Wu,Y., Dong,J., Feng,S., Zhao,Q., Duan,P., Xiong,M., Wen,Y., Lv,C.,
            Wang,X. and Yuan,S.
  TITLE     Maternal UHRF1 Is Essential for Transcription Landscapes and
            Repression of Repetitive Elements During the Maternal-to-Zygotic
            Transition
  JOURNAL   Front Cell Dev Biol 8, 610773 (2021)
   PUBMED   33634103
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2204)
  AUTHORS   Lui,J.H., Nowakowski,T.J., Pollen,A.A., Javaherian,A.,
            Kriegstein,A.R. and Oldham,M.C.
  TITLE     Radial glia require PDGFD-PDGFRbeta signalling in human but not
            mouse neocortex
  JOURNAL   Nature 515 (7526), 264-268 (2014)
   PUBMED   25391964
REFERENCE   6  (bases 1 to 2204)
  AUTHORS   Wong,J.C., Zhang,Y., Lieuw,K.H., Tran,M.T., Forgo,E.,
            Weinfurtner,K., Alzamora,P., Kogan,S.C., Akagi,K., Wolff,L., Le
            Beau,M.M., Killeen,N. and Shannon,K.
  TITLE     Use of chromosome engineering to model a segmental deletion of
            chromosome band 7q22 found in myeloid malignancies
  JOURNAL   Blood 115 (22), 4524-4532 (2010)
   PUBMED   20233966
REFERENCE   7  (bases 1 to 2204)
  AUTHORS   Malcuit,C., Trask,M.C., Santiago,L., Beaudoin,E., Tremblay,K.D. and
            Mager,J.
  TITLE     Identification of novel oocyte and granulosa cell markers
  JOURNAL   Gene Expr Patterns 9 (6), 404-410 (2009)
   PUBMED   19539053
REFERENCE   8  (bases 1 to 2204)
  AUTHORS   Kim,T., Kim,K., Lee,S.H., So,H.S., Lee,J., Kim,N. and Choi,Y.
  TITLE     Identification of LRRc17 as a negative regulator of receptor
            activator of NF-kappaB ligand (RANKL)-induced osteoclast
            differentiation
  JOURNAL   J Biol Chem 284 (22), 15308-15316 (2009)
   PUBMED   19336404
  REMARK    GeneRIF: These results demonstrated a novel inhibitory activity of
            LRRc17 in RANKL-induced osteoclastogenesis.
REFERENCE   9  (bases 1 to 2204)
  AUTHORS   Kratz,C.P., Emerling,B.M., Donovan,S., Laig-Webster,M.,
            Taylor,B.R., Thompson,P., Jensen,S., Banerjee,A., Bonifas,J.,
            Makalowski,W., Green,E.D., Le Beau,M.M. and Shannon,K.M.
  TITLE     Candidate gene isolation and comparative analysis of a commonly
            deleted segment of 7q22 implicated in myeloid malignancies
  JOURNAL   Genomics 77 (3), 171-180 (2001)
   PUBMED   11597142
REFERENCE   10 (bases 1 to 2204)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF914556.1, AK018071.1 and CD741871.1.
            
            On or before Nov 30, 2007 this sequence version replaced
            XM_904948.2, XM_919092.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC030317.1, AK018071.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                CF914556.1         1-36
            37-2184             AK018071.1         3-2150
            2185-2204           CD741871.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..2204
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 9.89 cM"
     gene            1..2204
                     /gene="Lrrc17"
                     /gene_synonym="37kDa; 4833425M04Rik; 6130400C22Rik; P37nb"
                     /note="leucine rich repeat containing 17"
                     /db_xref="GeneID:74511"
                     /db_xref="MGI:MGI:1921761"
     exon            1..193
                     /gene="Lrrc17"
                     /gene_synonym="37kDa; 4833425M04Rik; 6130400C22Rik; P37nb"
                     /inference="alignment:Splign:2.1.0"
     exon            194..1093
                     /gene="Lrrc17"
                     /gene_synonym="37kDa; 4833425M04Rik; 6130400C22Rik; P37nb"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1249
                     /gene="Lrrc17"
                     /gene_synonym="37kDa; 4833425M04Rik; 6130400C22Rik; P37nb"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..2197
                     /gene="Lrrc17"
                     /gene_synonym="37kDa; 4833425M04Rik; 6130400C22Rik; P37nb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttaaaacc tcagcagagt gttctgtgct ccacgcacag cattagtgca acatgagggc
       61 tggatgcagc tggctctcgg gaggacgtcc tcgcctgctg caggacagag aagactgaga
      121 ctgggaggca aacctgggtg cagccggaaa ggtccagata gatgagcttg tggcatccgt
      181 tccccaagtt caggagctct gcacacccca gttgggcctt actctccccg acctgtgttt
      241 gctaaggcta cccaaacttg gattccagag gaagactttc ttgttccttc tgcctggggc
      301 cagctgaacg tcagaatgcg catagtggcc atcttgcttc tgttctgcct ttgcagagct
      361 gctgagcctc gcaagtccag ccctggtgtt ttgagaagcc aaggcaatcc cagccgcagc
      421 cacggccgtg gtggcaggag gggctccagc ccagtcaaac gctatgcacc aggcctgcct
      481 tgtgatgtgt acacttatct ccatgaaaaa tacctagact gccaagaaag gaaactagtc
      541 tatgtgttgc ctgactggcc tcaagatttg ctgcacatgc tgctagcaag aaacaaaatc
      601 cgcgtgttaa agaacaacat gtttgctaag tttaaaaggc tgaagagcct ggacctgcag
      661 cagaacgaga tctccaaaat tgagagcgag gcgttctttg gtttaaataa acttaccacc
      721 ctcttgttgc agcacaacca gatcaaggtg ctgacagagg aggcgttcat ttacacgccg
      781 ctcctgagct acctgcggct ctatgacaac ccctggcact gcacttgtga gctagagacg
      841 ctcatttcca tgctgcagat tccacggaac cggaatctgg ggaactacgc caagtgcgga
      901 agcccaccag cactgagaaa taaaaagttg ctgcagctaa aacctcaaga gctgtgtgat
      961 gaagaggaga aggagcaact ggaccccaaa ccccaagtgt cggggatacc cgcagtcatc
     1021 aggccagaag cagactccac tctgtgccac aattacgtgt ttcccataca aaccctagac
     1081 tgcaagagga aagagttgaa gaaagtccca agcaacatcc ctccagacat agtgaagctt
     1141 gacctgtcat ccaacaaaat cagacagctc cgacccaagg agtttgaaga tgttcacgaa
     1201 ctaaagaagt taaacctaag cagcaatggc attgagttta tagatcctgc tgccttttta
     1261 gggctcatac acctagaaga gctcgactta tcaaacaaca gcctgcagaa ctttgactat
     1321 ggcgtgttag aggatttgta ctttctgaaa ctcctgtggc tcagagataa cccttggagg
     1381 tgtgactaca gcatccacta cctctactac tggttaaagc accactacaa cgtccactat
     1441 aacggtctgg aatgcaaaac gccggaagaa tacaaagggt ggtctgtggg gaaatacgta
     1501 cggagttact atgaagaatg ccccaaggac aagctgccag cctaccctga gacgtttgac
     1561 caggacacag aagatgatga atggcagaaa atacacagag atcacccagc aaagaagcac
     1621 agagtgagaa tcaccattgt ggggtagtta actaccgaac cgtcccagct agacccggct
     1681 gcacagcgct gtgtgggcgt ggggaaccgc atgtttacat tcggatgaat tgtgggtttg
     1741 gggatttagc tcagtggtag agcgcttgcc tagcaagcgc aaggccctgg gttcggtcct
     1801 cagctctgga aaaaaaaaac aaaacatttg gatgaattgt gatacctatt atgcagggta
     1861 atcaagctac aaggaggttc ctctgatttg ttagcaacaa ttattcggct gtggcaagtt
     1921 tgataatcta gggaaacctg cccgcctgcg gatcagactc ccatgacaag agtacacagt
     1981 gggccagaac tgctggtaca tgtccacagc tccaacacta aagctgaggc aggaggaccg
     2041 tggtgccaac ctgggctaca aagccagaaa cagtctcaaa agaacccaac tattccacac
     2101 tggtgacatg agggagttgg atattaatga tggtattaga atttcatagt gcatatgttt
     2161 ttagtggctt tttgaaataa aagtttaaaa aaaaaaaaaa aaaa
//
