LOCUS       XM_011240461            7643 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus low density lipoprotein receptor-related
            protein 8, apolipoprotein e receptor (Lrp8), transcript variant X8,
            mRNA.
ACCESSION   XM_011240461
VERSION     XM_011240461.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_011240461.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7643
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..7643
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /note="low density lipoprotein receptor-related protein 8,
                     apolipoprotein e receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 5 ESTs, 3663 long SRA reads, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 20 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
     CDS             259..3114
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /codon_start=1
                     /product="low-density lipoprotein receptor-related protein
                     8 isoform X8"
                     /protein_id="XP_011238763.1"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
                     /translation="MGRPELGALRPLALLLLLLLQLQHLSAADPLPGGQGPVKECEED
                     QFRCRNERCIPLVWRCDEDNDCSDNSDEDDCPKRTCADSDFTCDNGHCIPERWKCDGE
                     EECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTL
                     CAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERW
                     VCDRQFDCEDRSDEAAELCGRAGQGTTATPAACAPTAQFTCRSGECIHLGWRCDGDRD
                     CKDKSDEADCSAPGPCRENEFQCGDGTCVLAIKRCNQERDCPDGSDEAGCLQESTCEG
                     PRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCVAPSFPGNRRHPRGLNECLHNNG
                     GCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHP
                     GYEMDTLTKNCKAVAGKSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVAT
                     NRIYWCDLSYRKIYSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVHKHIYWTDSGNK
                     TISVATTDGRRRCTLFSRELSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQT
                     LVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVA
                     VFEDKVFWTDLENEAIFSANRLNGLEIAILAENLNNPHDIVIFHELKQPKAADACDLS
                     AQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASAMT
                     RTVPATTRAPGTTIHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHS
                     QHYGNEGSQMGSTVTAAVIGVIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYR
                     KTTEEEEEDELHIGRTAQIGHVYPARVALSLEDDGLP"
ORIGIN      
        1 gaggcggcgg cgggagggag cgcgcgcgcc ggcggcggct gcccagggcc ggggccgcgc
       61 gcccagcctg agcccgcccc gccgccgagc gtcaccgaac ctgcttgaaa tgcagccggg
      121 gagccggggc gggcggcagc ggtggtggtg gcggcggcgg cagcggcagc cccggcgccg
      181 cggcaaggac ttggcgggct gaggcgcggc ggcggcgcgg gggtctcggg gcgcggcggc
      241 cggagccccg ggcccgctat gggccgccca gaactgggcg cgctccggcc gctggcgctg
      301 ttgctgttgc tgctgctgca gcttcagcat ctctccgcag cggatccgct gccgggcggc
      361 caagggccag tcaaggagtg tgaagaggac cagtttcggt gtcggaacga gcgctgcatt
      421 cccttggtgt ggagatgcga tgaggacaac gactgctcgg acaacagcga cgaggacgac
      481 tgccccaaga ggacctgcgc ggacagcgac ttcacctgtg acaatggcca ctgcatccca
      541 gagcggtgga agtgcgacgg cgaggaggag tgtcccgatg gctctgacga atcgaaggcc
      601 acgtgctcca gtgaagagtg tcctgccgag aagttaagct gcggacccac cagccacaag
      661 tgtgtgcctg cctcatggcg ctgcgacgga gagaaggact gtgagggtgg tgctgacgag
      721 gccggctgtc ccaccttgtg cgccccgcac gagttccagt gcagcaaccg ctcctgcctg
      781 gcctctgtgt tcgtgtgcga tggtgacgat gactgcggcg acggcagcga cgagcgtggc
      841 tgctcggacc cggcctgccc gccccgcgag ttccgctgtg gaggaggcgg cacctgcatc
      901 cctgagcgct gggtctgcga ccgccagttc gactgcgagg accgctcgga tgaggcggcc
      961 gagctctgcg ggcgagcggg ccaggggacc acggccacgc cagcagcctg cgccccgacc
     1021 gcccagttca cctgccgcag cggcgagtgc atacacctgg gctggcgctg cgacggcgac
     1081 cgcgactgca aggacaagtc tgacgaggcc gactgctcag caccaggacc ctgccgcgag
     1141 aatgagttcc agtgtgggga tgggacttgc gttcttgcca tcaaacggtg caaccaggag
     1201 cgggactgcc cggacgggag tgacgaagcg ggctgccttc aggagtcaac ttgtgagggt
     1261 ccccgcagat ttcagtgtaa gagtggcgag tgcgtggacg gcgggaaagt gtgtgatgat
     1321 cagagggact gccgggactg gtcggatgag cctcagaaag tgtgtgttgc accatcattc
     1381 ccgggaaaca ggaggcatcc cagggggcta aatgagtgtc tgcacaataa cggcggctgt
     1441 tcccacatct gcactgacct caagatcggc tttgagtgca cgtgcccagc aggcttccag
     1501 ctcttggacc agaagacctg tggtgacatt gatgaatgcc aggacccgga tgcctgcagc
     1561 caaatctgcg tgaattacaa gggctacttt aagtgtgaat gccaccctgg ctatgagatg
     1621 gatacactga ccaagaactg caaagctgta gccggcaaga gcccatctct gatcttcacg
     1681 aaccgacacg aggtgcggag gatagacctg gtgaagcggg actactcgcg cctcatcccc
     1741 atgctcaaga atgtcgtggc gctggacgtg gaagtagcca ccaatcgcat atactggtgc
     1801 gacctctcct accgcaagat ctacagcgcc cacatggaca aggccagcat cccggacgag
     1861 caggtggtcc tcattgatga gcagctgcac tccccggagg gcctggcggt ggactgggtc
     1921 cataagcaca tctactggac agactcaggc aataagacca tctcagtggc cacaaccgat
     1981 ggacgccgcc gctgtactct cttcagccgt gagctcagtg agccccgagc cattgccgtt
     2041 gaccccctgc gagggttcat gtactggtct gactggggtt tccaggcaaa gattgagaag
     2101 gctgggctca atggtgcaga ccggcaaaca ctggtttcag acaacattga atggcccaat
     2161 ggaatcaccc tggacttgct gagccagcgt ttgtactggg tggactccaa gctgcaccaa
     2221 ctatccagca ttgacttcaa tggaggcaac agaaagatgc tgatcttctc cactgacttc
     2281 ctgagtcacc cttttggggt tgctgtattt gaggacaagg tattctggac agacctggag
     2341 aatgaggcca ttttcagcgc aaatcggctc aatggcctgg aaatcgccat cctggccgag
     2401 aacctcaata acccacatga cattgtaatc ttccacgagc tgaagcagcc aaaggctgca
     2461 gatgcctgtg acctgagtgc ccagcccaac ggcggctgtg aatacctgtg ccttcctgct
     2521 cctcaaatct ccagccactc ccccaagtac acgtgtgcct gtcctgacac gatgtggctg
     2581 ggcccagaca tgaagagatg ctaccgagca cctcagtcta cctcaactac aaccttagcc
     2641 tctgccatga caaggacagt acctgctacc acaagagctc ctgggacaac catccacgac
     2701 cctacctacc agaaccatag cacagagacg ccaagccaga cagctgccgc ccctcactcg
     2761 gttaacgtcc ctagggctcc cagcaccagc ccatccaccc cgagccctgc taccagcaac
     2821 cactcccagc attatgggaa tgaaggcagc cagatgggct caacagtcac cgctgctgtc
     2881 attggggtca tcgtgcccat agtggtaata gccctgctat gtatgagtgg gtacctcatc
     2941 tggaggaact ggaagcggaa gaacaccaag agcatgaatt tcgacaaccc agtgtacagg
     3001 aaaacgacag aagaggaaga ggaagatgag cttcacatag ggaggacagc tcagattggc
     3061 cacgtctacc ccgcacgagt ggcattaagt cttgaagatg atggactgcc ctgaggatgg
     3121 gcccacccac ttcgtgcctc atggagttca gtcctatgca ctactctctc tggatggtgt
     3181 gtgattggat gagtgccatt tctatatatg ggtctgtgtg agtgtgtgtg tgtgtgtgtg
     3241 tgagtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tatgtgactt
     3301 tttttaaatt tatgttgcgg aaaggtaacc acaaagttat gatgaactgc aaacatccaa
     3361 aggatgtgaa agtttttata tgtataatgt tttatacact ttttaactgg ttgcactacc
     3421 cgtgaagaat tcatgggaca gccactgctg agtgactaac atgatgcaca taaccaaacg
     3481 gggccaatgg tacaaacttc actcatcatt tgaatacagt atttacagag gatgtttgag
     3541 ttgagagctt ttttaggttt gaggggcttg atttttttgt aaataaaatt atgctttgtg
     3601 gctatccatc aacataagta taaaaagaaa gaacgcttca acccccttcc ccatttagat
     3661 tatttattaa catatttcga aagtaaggtt agctctataa ataatttaga gaggtgagag
     3721 tatttatttt tggtatggct ggctcactgc acagactctg tgtttatgtg tgtgtgtctg
     3781 tgtgagagaa gaaaaatctg tagagaagag gcacgcttat gactattgtt caaatacata
     3841 aaaacagtta ttttaaaaca gtccacaaga ggggtgtcta gttttcagag acacttcaga
     3901 aactttgctc agaaaacaga tgctacagtt tgtgcaggca tgcggtagga aaggtagatc
     3961 acctctggct actcctgagg ccctgctgag ccagcaaaat gctttccagt tcctctttgg
     4021 ctctcacgat gcccacctag gctttctggc cagtgtactg aacagtgcta caagccctca
     4081 ggagctcaag atagcagagt ccttctttca aagcccagct tagtgaggac ttgggtcaac
     4141 ttcagtaagc ttcctctgaa gcaactgaag gccgagcctt tagagcaacc attgtcaacc
     4201 tttgtgggtc gcctaagagc atcgcaaacc agatatttac attatgattc ataacagtga
     4261 caatcacagt tatgaggtag aaaggaaagg gattttatgg ttgggggtta gtccaacaag
     4321 agggacagtg ttaatgcttc tgaagcatca ggaaggttga aagccactgc tctagagcca
     4381 agtgagtgca tgtctagggt tcccatgttt acagtaagga ccggctcagg cactgaccct
     4441 ctgagtcacg tgaatgagga cgaagaattt ggaataggtt tggttacatc tatttctcat
     4501 ccccttattt tccaccattt aaaaataata aacatgtttc ttaccaccgt atgttcatat
     4561 ggataagact aagtccaaaa aggtgactac atccaaattt atatttcggg gaaataccat
     4621 gagataatta tagcatactg ggcatgtgtc cacacacgga ttggtttcac tgctttataa
     4681 ataaaaggaa caactctggg tatttgtata gaattttctt catatgtaac atctttccat
     4741 ttcctgagcc ttgggggtgg ggtgggagaa tgccacttgc tgtctgtgaa gtccactgtt
     4801 ggaaacataa ttccatagtc ccagaaggaa ttcagtcccc accaacttac tctttcaaag
     4861 tgtggtcttc ccgcgactct gcagctctgc agttcactcc agctgaacga ccagggacaa
     4921 gtacaacaca ggagtttggc ttaagtggca gcagactaat atctaaagtt gacataactg
     4981 aaatctgaca tttgaggcat atgtctccgc gtccccacac accggcttga gtggctcacc
     5041 tgcttgatgt cctttcaact tccggggaga ccgtctggag acctgtcatc ctgtcatcct
     5101 gttcctagga gcttgctcta tgtcactcat gttttcctaa cctttaaaaa atggctgtgt
     5161 tccaagcctg gccattatgt ctgacaatgc acgtgttgat ggtcttgaga tatacagtga
     5221 ctaaatgcag ctgacccctg acccattcca aacagtctca aggacaggca gctgagtccc
     5281 ctgcagctcg cctgtcactg ttcatccagg aatggagagg agaaatcaag tttactaaag
     5341 aaaaaggtta gaagtgaaat catcaaaatt tacacaagat aggcagggtt tttcccttta
     5401 atctgcctcc aaggaaactg aagcagtgat agtgtatagt ttctgaacaa acgttcatag
     5461 cctagccttc acaacaaggc tgaaacatac cgtctagggt ttccgaaaga tgaaagaatt
     5521 catatcagaa ataccatgtt tcctgaatgt gccacagctg cagtctaaaa gcagcctaca
     5581 gtaaacagat gggcaaatcc agggacggcc ggagagcgga agcactctga gggaccagac
     5641 cgacctcctt ctatccttgg aaactttttg agcctcattc tgaggtgtaa ttcagacttc
     5701 tgttgccttt cgcctctgcc tatgtatcca cagccaataa cagctgaaag gaaactcagt
     5761 aataaaccaa aaggacagaa aattcaacaa acgttactta ttaaaacgaa gccaacccct
     5821 tccttctcta gaagacaact ctgagcagcc tgaacaaggt ctcagacctg catcctctcc
     5881 acagctatct gcccagtgga ttgaaggcac taacagaaac gactttcctg aaacaagaaa
     5941 ctacagcttt gtttactctt cagaatgtgt gtatgtgtgt gcacagaggg acaggatgag
     6001 acggcttctg acaaggagta agaagaatga gacaggattt aaactgatgt cagtgaacac
     6061 tgttgaagcc ctccagttat cctcatgtct tagtaacata ctcagagtat tcactcgctg
     6121 ctgtgtgcca ggctttgcag acattgcagg tcaattcaac agttttcacc ctttccaaac
     6181 tcacagcagt acatatggat acaaaaagaa aaaaaaattt tcccatagat ttcacctaga
     6241 ctactcccaa ggcacaacaa aagagatggg ccattttacc tgaagaggtg gaaataggtc
     6301 tacataggaa tgacccaaag caatgtctta aaacttaaaa agtggtgttc aggctgcttc
     6361 tatgagaaga ggctgggctc agactgggag tgaatcagca gcaggaattt caaggaaaac
     6421 atggagttcc ttacacctgg aataaagaac tttagcaggg ttggcaagat gtgaaactgg
     6481 atggaaagac aagttcaaca caagcacttt ataaaatagt ctgatgtaag taagcagaca
     6541 tttgtttggt cgtcggttcc tgtgtgcaag gcatcatggg aaactccctg ccagcacttg
     6601 gcaggcatta ttccacctca agctttccag agaccacagg gaaatgactg ttttctttat
     6661 ttgagccaga ggttttgata tggttcctga aggctaacag aagggcggtg ggcttgtcaa
     6721 cagaagcacg ccatgttgcc gagcacctgt gaggtcctca cgtgggagga agagaacaag
     6781 gtggttaaga tagagaatct ggagagggta ccccaatcac actacagtcg ggtgctactg
     6841 ggtggaggag aaaaccatcc taaccccaca gcactgcaaa gacgctcctg tcccgccaca
     6901 ctcccaccat cacgaacatc agtaagtcag cagtttcaga ttctgccatt tccttcccca
     6961 taaaagcatg aagataggga gtcggtgtcc ttacgcttta tttttagggt atttgggagt
     7021 ttccaggatg tgaagaagtt aggtggagga aattacggct tcaatttttt tcagttaact
     7081 acaggacgct tcattcaggc cgggcaccat gtgcacagtc ttaagaagca gcaggaactg
     7141 catttgcaaa cacgtgttgt aaaaaattaa ttttaaaaaa gctacctgta taaatataaa
     7201 tatatatatt taaagacaag gttttgatac ttttttttta aaaaacaaaa actacaagag
     7261 aagactgtac aaaccacggg cttttaaaat agcattttgc tctctacaag ctgttaatgt
     7321 caggggtgag gggtgaggga ctggtttgca aacacactat ccaaatggat ttgcttgttt
     7381 tgtcaagcca ccctccaaat taccatattt ggtgtaatag tagggcatgt aaagttattg
     7441 ggtcccatta accatttctg ctcttgtcat gtcattccgg gttccgttag ctcccgtact
     7501 cggcaatcca gcttcttcca gaggcagagg ggctgaagga agtgtgctcc atttcactag
     7561 ctgtactgac atcatccaca tgtggacatt tgtaatatca gtacactatt tctagagaga
     7621 ttaaattcat tttttaaaat ctg
//
