LOCUS       XM_011240456            7781 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus low density lipoprotein receptor-related
            protein 8, apolipoprotein e receptor (Lrp8), transcript variant X3,
            mRNA.
ACCESSION   XM_011240456
VERSION     XM_011240456.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_011240456.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7781
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..7781
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /note="low density lipoprotein receptor-related protein 8,
                     apolipoprotein e receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 6 ESTs, 3553 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 22 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
     CDS             259..3252
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /codon_start=1
                     /product="low-density lipoprotein receptor-related protein
                     8 isoform X3"
                     /protein_id="XP_011238758.1"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
                     /translation="MGRPELGALRPLALLLLLLLQLQHLSAADPLPGGQGPVKECEED
                     QFRCRNERCIPLVWRCDEDNDCSDNSDEDDCPKRTCADSDFTCDNGHCIPERWKCDGE
                     EECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTL
                     CAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERW
                     VCDRQFDCEDRSDEAAELCGRAGQGTTATPAACAPTAQFTCRSGECIHLGWRCDGDRD
                     CKDKSDEADCSAPGPCRENEFQCGDGTCVLAIKRCNQERDCPDGSDEAGCLQESTCEG
                     PRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCGLNECLHNNGGCSHICTDLKIGF
                     ECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHPGYEMDTLTKNCKA
                     VAGKSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKI
                     YSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATTDGRRRC
                     TLFSRELSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQTLVSDNIEWPNGIT
                     LDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAVFEDKVFWTDLEN
                     EAIFSANRLNGLEIAILAENLNNPHDIVIFHELKQPKAADACDLSAQPNGGCEYLCLP
                     APQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASAMTRTVPATTRAPGTT
                     IHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHSQHYGNEGSQMGST
                     VTAAVIGVIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEEEDELHI
                     GRTAQIGHVYPAAISNYDRPLWAEPCLGETRDLEDPAPALKELFVLPGEPRSQLHQLP
                     KNPLSELPVVKCKRVALSLEDDGLP"
ORIGIN      
        1 gaggcggcgg cgggagggag cgcgcgcgcc ggcggcggct gcccagggcc ggggccgcgc
       61 gcccagcctg agcccgcccc gccgccgagc gtcaccgaac ctgcttgaaa tgcagccggg
      121 gagccggggc gggcggcagc ggtggtggtg gcggcggcgg cagcggcagc cccggcgccg
      181 cggcaaggac ttggcgggct gaggcgcggc ggcggcgcgg gggtctcggg gcgcggcggc
      241 cggagccccg ggcccgctat gggccgccca gaactgggcg cgctccggcc gctggcgctg
      301 ttgctgttgc tgctgctgca gcttcagcat ctctccgcag cggatccgct gccgggcggc
      361 caagggccag tcaaggagtg tgaagaggac cagtttcggt gtcggaacga gcgctgcatt
      421 cccttggtgt ggagatgcga tgaggacaac gactgctcgg acaacagcga cgaggacgac
      481 tgccccaaga ggacctgcgc ggacagcgac ttcacctgtg acaatggcca ctgcatccca
      541 gagcggtgga agtgcgacgg cgaggaggag tgtcccgatg gctctgacga atcgaaggcc
      601 acgtgctcca gtgaagagtg tcctgccgag aagttaagct gcggacccac cagccacaag
      661 tgtgtgcctg cctcatggcg ctgcgacgga gagaaggact gtgagggtgg tgctgacgag
      721 gccggctgtc ccaccttgtg cgccccgcac gagttccagt gcagcaaccg ctcctgcctg
      781 gcctctgtgt tcgtgtgcga tggtgacgat gactgcggcg acggcagcga cgagcgtggc
      841 tgctcggacc cggcctgccc gccccgcgag ttccgctgtg gaggaggcgg cacctgcatc
      901 cctgagcgct gggtctgcga ccgccagttc gactgcgagg accgctcgga tgaggcggcc
      961 gagctctgcg ggcgagcggg ccaggggacc acggccacgc cagcagcctg cgccccgacc
     1021 gcccagttca cctgccgcag cggcgagtgc atacacctgg gctggcgctg cgacggcgac
     1081 cgcgactgca aggacaagtc tgacgaggcc gactgctcag caccaggacc ctgccgcgag
     1141 aatgagttcc agtgtgggga tgggacttgc gttcttgcca tcaaacggtg caaccaggag
     1201 cgggactgcc cggacgggag tgacgaagcg ggctgccttc aggagtcaac ttgtgagggt
     1261 ccccgcagat ttcagtgtaa gagtggcgag tgcgtggacg gcgggaaagt gtgtgatgat
     1321 cagagggact gccgggactg gtcggatgag cctcagaaag tgtgtgggct aaatgagtgt
     1381 ctgcacaata acggcggctg ttcccacatc tgcactgacc tcaagatcgg ctttgagtgc
     1441 acgtgcccag caggcttcca gctcttggac cagaagacct gtggtgacat tgatgaatgc
     1501 caggacccgg atgcctgcag ccaaatctgc gtgaattaca agggctactt taagtgtgaa
     1561 tgccaccctg gctatgagat ggatacactg accaagaact gcaaagctgt agccggcaag
     1621 agcccatctc tgatcttcac gaaccgacac gaggtgcgga ggatagacct ggtgaagcgg
     1681 gactactcgc gcctcatccc catgctcaag aatgtcgtgg cgctggacgt ggaagtagcc
     1741 accaatcgca tatactggtg cgacctctcc taccgcaaga tctacagcgc ccacatggac
     1801 aaggccagca tcccggacga gcaggtggtc ctcattgatg agcagctgca ctccccggag
     1861 ggcctggcgg tggactgggt ccataagcac atctactgga cagactcagg caataagacc
     1921 atctcagtgg ccacaaccga tggacgccgc cgctgtactc tcttcagccg tgagctcagt
     1981 gagccccgag ccattgccgt tgaccccctg cgagggttca tgtactggtc tgactggggt
     2041 ttccaggcaa agattgagaa ggctgggctc aatggtgcag accggcaaac actggtttca
     2101 gacaacattg aatggcccaa tggaatcacc ctggacttgc tgagccagcg tttgtactgg
     2161 gtggactcca agctgcacca actatccagc attgacttca atggaggcaa cagaaagatg
     2221 ctgatcttct ccactgactt cctgagtcac ccttttgggg ttgctgtatt tgaggacaag
     2281 gtattctgga cagacctgga gaatgaggcc attttcagcg caaatcggct caatggcctg
     2341 gaaatcgcca tcctggccga gaacctcaat aacccacatg acattgtaat cttccacgag
     2401 ctgaagcagc caaaggctgc agatgcctgt gacctgagtg cccagcccaa cggcggctgt
     2461 gaatacctgt gccttcctgc tcctcaaatc tccagccact cccccaagta cacgtgtgcc
     2521 tgtcctgaca cgatgtggct gggcccagac atgaagagat gctaccgagc acctcagtct
     2581 acctcaacta caaccttagc ctctgccatg acaaggacag tacctgctac cacaagagct
     2641 cctgggacaa ccatccacga ccctacctac cagaaccata gcacagagac gccaagccag
     2701 acagctgccg cccctcactc ggttaacgtc cctagggctc ccagcaccag cccatccacc
     2761 ccgagccctg ctaccagcaa ccactcccag cattatggga atgaaggcag ccagatgggc
     2821 tcaacagtca ccgctgctgt cattggggtc atcgtgccca tagtggtaat agccctgcta
     2881 tgtatgagtg ggtacctcat ctggaggaac tggaagcgga agaacaccaa gagcatgaat
     2941 ttcgacaacc cagtgtacag gaaaacgaca gaagaggaag aggaagatga gcttcacata
     3001 gggaggacag ctcagattgg ccacgtctac cccgcagcaa tcagcaacta tgatcgccca
     3061 ctgtgggcag agccctgtct tggggagacc agagacctgg aagacccagc ccctgccctc
     3121 aaggagcttt ttgtcttgcc gggagaacca aggtcacagc ttcaccaact cccgaagaac
     3181 cctctttccg agctgcctgt cgtcaagtgc aagcgagtgg cattaagtct tgaagatgat
     3241 ggactgccct gaggatgggc ccacccactt cgtgcctcat ggagttcagt cctatgcact
     3301 actctctctg gatggtgtgt gattggatga gtgccatttc tatatatggg tctgtgtgag
     3361 tgtgtgtgtg tgtgtgtgtg agtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     3421 tgtgtgtgta tgtgactttt tttaaattta tgttgcggaa aggtaaccac aaagttatga
     3481 tgaactgcaa acatccaaag gatgtgaaag tttttatatg tataatgttt tatacacttt
     3541 ttaactggtt gcactacccg tgaagaattc atgggacagc cactgctgag tgactaacat
     3601 gatgcacata accaaacggg gccaatggta caaacttcac tcatcatttg aatacagtat
     3661 ttacagagga tgtttgagtt gagagctttt ttaggtttga ggggcttgat ttttttgtaa
     3721 ataaaattat gctttgtggc tatccatcaa cataagtata aaaagaaaga acgcttcaac
     3781 ccccttcccc atttagatta tttattaaca tatttcgaaa gtaaggttag ctctataaat
     3841 aatttagaga ggtgagagta tttatttttg gtatggctgg ctcactgcac agactctgtg
     3901 tttatgtgtg tgtgtctgtg tgagagaaga aaaatctgta gagaagaggc acgcttatga
     3961 ctattgttca aatacataaa aacagttatt ttaaaacagt ccacaagagg ggtgtctagt
     4021 tttcagagac acttcagaaa ctttgctcag aaaacagatg ctacagtttg tgcaggcatg
     4081 cggtaggaaa ggtagatcac ctctggctac tcctgaggcc ctgctgagcc agcaaaatgc
     4141 tttccagttc ctctttggct ctcacgatgc ccacctaggc tttctggcca gtgtactgaa
     4201 cagtgctaca agccctcagg agctcaagat agcagagtcc ttctttcaaa gcccagctta
     4261 gtgaggactt gggtcaactt cagtaagctt cctctgaagc aactgaaggc cgagccttta
     4321 gagcaaccat tgtcaacctt tgtgggtcgc ctaagagcat cgcaaaccag atatttacat
     4381 tatgattcat aacagtgaca atcacagtta tgaggtagaa aggaaaggga ttttatggtt
     4441 gggggttagt ccaacaagag ggacagtgtt aatgcttctg aagcatcagg aaggttgaaa
     4501 gccactgctc tagagccaag tgagtgcatg tctagggttc ccatgtttac agtaaggacc
     4561 ggctcaggca ctgaccctct gagtcacgtg aatgaggacg aagaatttgg aataggtttg
     4621 gttacatcta tttctcatcc ccttattttc caccatttaa aaataataaa catgtttctt
     4681 accaccgtat gttcatatgg ataagactaa gtccaaaaag gtgactacat ccaaatttat
     4741 atttcgggga aataccatga gataattata gcatactggg catgtgtcca cacacggatt
     4801 ggtttcactg ctttataaat aaaaggaaca actctgggta tttgtataga attttcttca
     4861 tatgtaacat ctttccattt cctgagcctt gggggtgggg tgggagaatg ccacttgctg
     4921 tctgtgaagt ccactgttgg aaacataatt ccatagtccc agaaggaatt cagtccccac
     4981 caacttactc tttcaaagtg tggtcttccc gcgactctgc agctctgcag ttcactccag
     5041 ctgaacgacc agggacaagt acaacacagg agtttggctt aagtggcagc agactaatat
     5101 ctaaagttga cataactgaa atctgacatt tgaggcatat gtctccgcgt ccccacacac
     5161 cggcttgagt ggctcacctg cttgatgtcc tttcaacttc cggggagacc gtctggagac
     5221 ctgtcatcct gtcatcctgt tcctaggagc ttgctctatg tcactcatgt tttcctaacc
     5281 tttaaaaaat ggctgtgttc caagcctggc cattatgtct gacaatgcac gtgttgatgg
     5341 tcttgagata tacagtgact aaatgcagct gacccctgac ccattccaaa cagtctcaag
     5401 gacaggcagc tgagtcccct gcagctcgcc tgtcactgtt catccaggaa tggagaggag
     5461 aaatcaagtt tactaaagaa aaaggttaga agtgaaatca tcaaaattta cacaagatag
     5521 gcagggtttt tccctttaat ctgcctccaa ggaaactgaa gcagtgatag tgtatagttt
     5581 ctgaacaaac gttcatagcc tagccttcac aacaaggctg aaacataccg tctagggttt
     5641 ccgaaagatg aaagaattca tatcagaaat accatgtttc ctgaatgtgc cacagctgca
     5701 gtctaaaagc agcctacagt aaacagatgg gcaaatccag ggacggccgg agagcggaag
     5761 cactctgagg gaccagaccg acctccttct atccttggaa actttttgag cctcattctg
     5821 aggtgtaatt cagacttctg ttgcctttcg cctctgccta tgtatccaca gccaataaca
     5881 gctgaaagga aactcagtaa taaaccaaaa ggacagaaaa ttcaacaaac gttacttatt
     5941 aaaacgaagc caaccccttc cttctctaga agacaactct gagcagcctg aacaaggtct
     6001 cagacctgca tcctctccac agctatctgc ccagtggatt gaaggcacta acagaaacga
     6061 ctttcctgaa acaagaaact acagctttgt ttactcttca gaatgtgtgt atgtgtgtgc
     6121 acagagggac aggatgagac ggcttctgac aaggagtaag aagaatgaga caggatttaa
     6181 actgatgtca gtgaacactg ttgaagccct ccagttatcc tcatgtctta gtaacatact
     6241 cagagtattc actcgctgct gtgtgccagg ctttgcagac attgcaggtc aattcaacag
     6301 ttttcaccct ttccaaactc acagcagtac atatggatac aaaaagaaaa aaaaattttc
     6361 ccatagattt cacctagact actcccaagg cacaacaaaa gagatgggcc attttacctg
     6421 aagaggtgga aataggtcta cataggaatg acccaaagca atgtcttaaa acttaaaaag
     6481 tggtgttcag gctgcttcta tgagaagagg ctgggctcag actgggagtg aatcagcagc
     6541 aggaatttca aggaaaacat ggagttcctt acacctggaa taaagaactt tagcagggtt
     6601 ggcaagatgt gaaactggat ggaaagacaa gttcaacaca agcactttat aaaatagtct
     6661 gatgtaagta agcagacatt tgtttggtcg tcggttcctg tgtgcaaggc atcatgggaa
     6721 actccctgcc agcacttggc aggcattatt ccacctcaag ctttccagag accacaggga
     6781 aatgactgtt ttctttattt gagccagagg ttttgatatg gttcctgaag gctaacagaa
     6841 gggcggtggg cttgtcaaca gaagcacgcc atgttgccga gcacctgtga ggtcctcacg
     6901 tgggaggaag agaacaaggt ggttaagata gagaatctgg agagggtacc ccaatcacac
     6961 tacagtcggg tgctactggg tggaggagaa aaccatccta accccacagc actgcaaaga
     7021 cgctcctgtc ccgccacact cccaccatca cgaacatcag taagtcagca gtttcagatt
     7081 ctgccatttc cttccccata aaagcatgaa gatagggagt cggtgtcctt acgctttatt
     7141 tttagggtat ttgggagttt ccaggatgtg aagaagttag gtggaggaaa ttacggcttc
     7201 aatttttttc agttaactac aggacgcttc attcaggccg ggcaccatgt gcacagtctt
     7261 aagaagcagc aggaactgca tttgcaaaca cgtgttgtaa aaaattaatt ttaaaaaagc
     7321 tacctgtata aatataaata tatatattta aagacaaggt tttgatactt tttttttaaa
     7381 aaacaaaaac tacaagagaa gactgtacaa accacgggct tttaaaatag cattttgctc
     7441 tctacaagct gttaatgtca ggggtgaggg gtgagggact ggtttgcaaa cacactatcc
     7501 aaatggattt gcttgttttg tcaagccacc ctccaaatta ccatatttgg tgtaatagta
     7561 gggcatgtaa agttattggg tcccattaac catttctgct cttgtcatgt cattccgggt
     7621 tccgttagct cccgtactcg gcaatccagc ttcttccaga ggcagagggg ctgaaggaag
     7681 tgtgctccat ttcactagct gtactgacat catccacatg tggacatttg taatatcagt
     7741 acactatttc tagagagatt aaattcattt tttaaaatct g
//
