LOCUS       XM_011240455            7817 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus low density lipoprotein receptor-related
            protein 8, apolipoprotein e receptor (Lrp8), transcript variant X2,
            mRNA.
ACCESSION   XM_011240455
VERSION     XM_011240455.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_011240455.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..7817
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /note="low density lipoprotein receptor-related protein 8,
                     apolipoprotein e receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 6 ESTs, 3546 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 23 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
     CDS             259..3288
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /codon_start=1
                     /product="low-density lipoprotein receptor-related protein
                     8 isoform X2"
                     /protein_id="XP_011238757.1"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
                     /translation="MGRPELGALRPLALLLLLLLQLQHLSAADPLPGGQGPVKECEED
                     QFRCRNERCIPLVWRCDEDNDCSDNSDEDDCPKRTCADSDFTCDNGHCIPERWKCDGE
                     EECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTL
                     CAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERW
                     VCDRQFDCEDRSDEAAELCGRAGQGTTATPAACAPTAQFTCRSGECIHLGWRCDGDRD
                     CKDKSDEADCSPGPCRENEFQCGDGTCVLAIKRCNQERDCPDGSDEAGCLQESTCEGP
                     RRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCVAPSFPGNRRHPRGLNECLHNNGG
                     CSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHPG
                     YEMDTLTKNCKAVAGKSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVATN
                     RIYWCDLSYRKIYSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKT
                     ISVATTDGRRRCTLFSRELSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQTL
                     VSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAV
                     FEDKVFWTDLENEAIFSANRLNGLEIAILAENLNNPHDIVIFHELKQPKAADACDLSA
                     QPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASAMTR
                     TVPATTRAPGTTIHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHSQ
                     HYGNEGSQMGSTVTAAVIGVIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYRK
                     TTEEEEEDELHIGRTAQIGHVYPAAISNYDRPLWAEPCLGETRDLEDPAPALKELFVL
                     PGEPRSQLHQLPKNPLSELPVVKCKRVALSLEDDGLP"
ORIGIN      
        1 gaggcggcgg cgggagggag cgcgcgcgcc ggcggcggct gcccagggcc ggggccgcgc
       61 gcccagcctg agcccgcccc gccgccgagc gtcaccgaac ctgcttgaaa tgcagccggg
      121 gagccggggc gggcggcagc ggtggtggtg gcggcggcgg cagcggcagc cccggcgccg
      181 cggcaaggac ttggcgggct gaggcgcggc ggcggcgcgg gggtctcggg gcgcggcggc
      241 cggagccccg ggcccgctat gggccgccca gaactgggcg cgctccggcc gctggcgctg
      301 ttgctgttgc tgctgctgca gcttcagcat ctctccgcag cggatccgct gccgggcggc
      361 caagggccag tcaaggagtg tgaagaggac cagtttcggt gtcggaacga gcgctgcatt
      421 cccttggtgt ggagatgcga tgaggacaac gactgctcgg acaacagcga cgaggacgac
      481 tgccccaaga ggacctgcgc ggacagcgac ttcacctgtg acaatggcca ctgcatccca
      541 gagcggtgga agtgcgacgg cgaggaggag tgtcccgatg gctctgacga atcgaaggcc
      601 acgtgctcca gtgaagagtg tcctgccgag aagttaagct gcggacccac cagccacaag
      661 tgtgtgcctg cctcatggcg ctgcgacgga gagaaggact gtgagggtgg tgctgacgag
      721 gccggctgtc ccaccttgtg cgccccgcac gagttccagt gcagcaaccg ctcctgcctg
      781 gcctctgtgt tcgtgtgcga tggtgacgat gactgcggcg acggcagcga cgagcgtggc
      841 tgctcggacc cggcctgccc gccccgcgag ttccgctgtg gaggaggcgg cacctgcatc
      901 cctgagcgct gggtctgcga ccgccagttc gactgcgagg accgctcgga tgaggcggcc
      961 gagctctgcg ggcgagcggg ccaggggacc acggccacgc cagcagcctg cgccccgacc
     1021 gcccagttca cctgccgcag cggcgagtgc atacacctgg gctggcgctg cgacggcgac
     1081 cgcgactgca aggacaagtc tgacgaggcc gactgctcac caggaccctg ccgcgagaat
     1141 gagttccagt gtggggatgg gacttgcgtt cttgccatca aacggtgcaa ccaggagcgg
     1201 gactgcccgg acgggagtga cgaagcgggc tgccttcagg agtcaacttg tgagggtccc
     1261 cgcagatttc agtgtaagag tggcgagtgc gtggacggcg ggaaagtgtg tgatgatcag
     1321 agggactgcc gggactggtc ggatgagcct cagaaagtgt gtgttgcacc atcattcccg
     1381 ggaaacagga ggcatcccag ggggctaaat gagtgtctgc acaataacgg cggctgttcc
     1441 cacatctgca ctgacctcaa gatcggcttt gagtgcacgt gcccagcagg cttccagctc
     1501 ttggaccaga agacctgtgg tgacattgat gaatgccagg acccggatgc ctgcagccaa
     1561 atctgcgtga attacaaggg ctactttaag tgtgaatgcc accctggcta tgagatggat
     1621 acactgacca agaactgcaa agctgtagcc ggcaagagcc catctctgat cttcacgaac
     1681 cgacacgagg tgcggaggat agacctggtg aagcgggact actcgcgcct catccccatg
     1741 ctcaagaatg tcgtggcgct ggacgtggaa gtagccacca atcgcatata ctggtgcgac
     1801 ctctcctacc gcaagatcta cagcgcccac atggacaagg ccagcatccc ggacgagcag
     1861 gtggtcctca ttgatgagca gctgcactcc ccggagggcc tggcggtgga ctgggtccat
     1921 aagcacatct actggacaga ctcaggcaat aagaccatct cagtggccac aaccgatgga
     1981 cgccgccgct gtactctctt cagccgtgag ctcagtgagc cccgagccat tgccgttgac
     2041 cccctgcgag ggttcatgta ctggtctgac tggggtttcc aggcaaagat tgagaaggct
     2101 gggctcaatg gtgcagaccg gcaaacactg gtttcagaca acattgaatg gcccaatgga
     2161 atcaccctgg acttgctgag ccagcgtttg tactgggtgg actccaagct gcaccaacta
     2221 tccagcattg acttcaatgg aggcaacaga aagatgctga tcttctccac tgacttcctg
     2281 agtcaccctt ttggggttgc tgtatttgag gacaaggtat tctggacaga cctggagaat
     2341 gaggccattt tcagcgcaaa tcggctcaat ggcctggaaa tcgccatcct ggccgagaac
     2401 ctcaataacc cacatgacat tgtaatcttc cacgagctga agcagccaaa ggctgcagat
     2461 gcctgtgacc tgagtgccca gcccaacggc ggctgtgaat acctgtgcct tcctgctcct
     2521 caaatctcca gccactcccc caagtacacg tgtgcctgtc ctgacacgat gtggctgggc
     2581 ccagacatga agagatgcta ccgagcacct cagtctacct caactacaac cttagcctct
     2641 gccatgacaa ggacagtacc tgctaccaca agagctcctg ggacaaccat ccacgaccct
     2701 acctaccaga accatagcac agagacgcca agccagacag ctgccgcccc tcactcggtt
     2761 aacgtcccta gggctcccag caccagccca tccaccccga gccctgctac cagcaaccac
     2821 tcccagcatt atgggaatga aggcagccag atgggctcaa cagtcaccgc tgctgtcatt
     2881 ggggtcatcg tgcccatagt ggtaatagcc ctgctatgta tgagtgggta cctcatctgg
     2941 aggaactgga agcggaagaa caccaagagc atgaatttcg acaacccagt gtacaggaaa
     3001 acgacagaag aggaagagga agatgagctt cacataggga ggacagctca gattggccac
     3061 gtctaccccg cagcaatcag caactatgat cgcccactgt gggcagagcc ctgtcttggg
     3121 gagaccagag acctggaaga cccagcccct gccctcaagg agctttttgt cttgccggga
     3181 gaaccaaggt cacagcttca ccaactcccg aagaaccctc tttccgagct gcctgtcgtc
     3241 aagtgcaagc gagtggcatt aagtcttgaa gatgatggac tgccctgagg atgggcccac
     3301 ccacttcgtg cctcatggag ttcagtccta tgcactactc tctctggatg gtgtgtgatt
     3361 ggatgagtgc catttctata tatgggtctg tgtgagtgtg tgtgtgtgtg tgtgtgagtg
     3421 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtatgtg acttttttta
     3481 aatttatgtt gcggaaaggt aaccacaaag ttatgatgaa ctgcaaacat ccaaaggatg
     3541 tgaaagtttt tatatgtata atgttttata cactttttaa ctggttgcac tacccgtgaa
     3601 gaattcatgg gacagccact gctgagtgac taacatgatg cacataacca aacggggcca
     3661 atggtacaaa cttcactcat catttgaata cagtatttac agaggatgtt tgagttgaga
     3721 gcttttttag gtttgagggg cttgattttt ttgtaaataa aattatgctt tgtggctatc
     3781 catcaacata agtataaaaa gaaagaacgc ttcaaccccc ttccccattt agattattta
     3841 ttaacatatt tcgaaagtaa ggttagctct ataaataatt tagagaggtg agagtattta
     3901 tttttggtat ggctggctca ctgcacagac tctgtgttta tgtgtgtgtg tctgtgtgag
     3961 agaagaaaaa tctgtagaga agaggcacgc ttatgactat tgttcaaata cataaaaaca
     4021 gttattttaa aacagtccac aagaggggtg tctagttttc agagacactt cagaaacttt
     4081 gctcagaaaa cagatgctac agtttgtgca ggcatgcggt aggaaaggta gatcacctct
     4141 ggctactcct gaggccctgc tgagccagca aaatgctttc cagttcctct ttggctctca
     4201 cgatgcccac ctaggctttc tggccagtgt actgaacagt gctacaagcc ctcaggagct
     4261 caagatagca gagtccttct ttcaaagccc agcttagtga ggacttgggt caacttcagt
     4321 aagcttcctc tgaagcaact gaaggccgag cctttagagc aaccattgtc aacctttgtg
     4381 ggtcgcctaa gagcatcgca aaccagatat ttacattatg attcataaca gtgacaatca
     4441 cagttatgag gtagaaagga aagggatttt atggttgggg gttagtccaa caagagggac
     4501 agtgttaatg cttctgaagc atcaggaagg ttgaaagcca ctgctctaga gccaagtgag
     4561 tgcatgtcta gggttcccat gtttacagta aggaccggct caggcactga ccctctgagt
     4621 cacgtgaatg aggacgaaga atttggaata ggtttggtta catctatttc tcatcccctt
     4681 attttccacc atttaaaaat aataaacatg tttcttacca ccgtatgttc atatggataa
     4741 gactaagtcc aaaaaggtga ctacatccaa atttatattt cggggaaata ccatgagata
     4801 attatagcat actgggcatg tgtccacaca cggattggtt tcactgcttt ataaataaaa
     4861 ggaacaactc tgggtatttg tatagaattt tcttcatatg taacatcttt ccatttcctg
     4921 agccttgggg gtggggtggg agaatgccac ttgctgtctg tgaagtccac tgttggaaac
     4981 ataattccat agtcccagaa ggaattcagt ccccaccaac ttactctttc aaagtgtggt
     5041 cttcccgcga ctctgcagct ctgcagttca ctccagctga acgaccaggg acaagtacaa
     5101 cacaggagtt tggcttaagt ggcagcagac taatatctaa agttgacata actgaaatct
     5161 gacatttgag gcatatgtct ccgcgtcccc acacaccggc ttgagtggct cacctgcttg
     5221 atgtcctttc aacttccggg gagaccgtct ggagacctgt catcctgtca tcctgttcct
     5281 aggagcttgc tctatgtcac tcatgttttc ctaaccttta aaaaatggct gtgttccaag
     5341 cctggccatt atgtctgaca atgcacgtgt tgatggtctt gagatataca gtgactaaat
     5401 gcagctgacc cctgacccat tccaaacagt ctcaaggaca ggcagctgag tcccctgcag
     5461 ctcgcctgtc actgttcatc caggaatgga gaggagaaat caagtttact aaagaaaaag
     5521 gttagaagtg aaatcatcaa aatttacaca agataggcag ggtttttccc tttaatctgc
     5581 ctccaaggaa actgaagcag tgatagtgta tagtttctga acaaacgttc atagcctagc
     5641 cttcacaaca aggctgaaac ataccgtcta gggtttccga aagatgaaag aattcatatc
     5701 agaaatacca tgtttcctga atgtgccaca gctgcagtct aaaagcagcc tacagtaaac
     5761 agatgggcaa atccagggac ggccggagag cggaagcact ctgagggacc agaccgacct
     5821 ccttctatcc ttggaaactt tttgagcctc attctgaggt gtaattcaga cttctgttgc
     5881 ctttcgcctc tgcctatgta tccacagcca ataacagctg aaaggaaact cagtaataaa
     5941 ccaaaaggac agaaaattca acaaacgtta cttattaaaa cgaagccaac cccttccttc
     6001 tctagaagac aactctgagc agcctgaaca aggtctcaga cctgcatcct ctccacagct
     6061 atctgcccag tggattgaag gcactaacag aaacgacttt cctgaaacaa gaaactacag
     6121 ctttgtttac tcttcagaat gtgtgtatgt gtgtgcacag agggacagga tgagacggct
     6181 tctgacaagg agtaagaaga atgagacagg atttaaactg atgtcagtga acactgttga
     6241 agccctccag ttatcctcat gtcttagtaa catactcaga gtattcactc gctgctgtgt
     6301 gccaggcttt gcagacattg caggtcaatt caacagtttt caccctttcc aaactcacag
     6361 cagtacatat ggatacaaaa agaaaaaaaa attttcccat agatttcacc tagactactc
     6421 ccaaggcaca acaaaagaga tgggccattt tacctgaaga ggtggaaata ggtctacata
     6481 ggaatgaccc aaagcaatgt cttaaaactt aaaaagtggt gttcaggctg cttctatgag
     6541 aagaggctgg gctcagactg ggagtgaatc agcagcagga atttcaagga aaacatggag
     6601 ttccttacac ctggaataaa gaactttagc agggttggca agatgtgaaa ctggatggaa
     6661 agacaagttc aacacaagca ctttataaaa tagtctgatg taagtaagca gacatttgtt
     6721 tggtcgtcgg ttcctgtgtg caaggcatca tgggaaactc cctgccagca cttggcaggc
     6781 attattccac ctcaagcttt ccagagacca cagggaaatg actgttttct ttatttgagc
     6841 cagaggtttt gatatggttc ctgaaggcta acagaagggc ggtgggcttg tcaacagaag
     6901 cacgccatgt tgccgagcac ctgtgaggtc ctcacgtggg aggaagagaa caaggtggtt
     6961 aagatagaga atctggagag ggtaccccaa tcacactaca gtcgggtgct actgggtgga
     7021 ggagaaaacc atcctaaccc cacagcactg caaagacgct cctgtcccgc cacactccca
     7081 ccatcacgaa catcagtaag tcagcagttt cagattctgc catttccttc cccataaaag
     7141 catgaagata gggagtcggt gtccttacgc tttattttta gggtatttgg gagtttccag
     7201 gatgtgaaga agttaggtgg aggaaattac ggcttcaatt tttttcagtt aactacagga
     7261 cgcttcattc aggccgggca ccatgtgcac agtcttaaga agcagcagga actgcatttg
     7321 caaacacgtg ttgtaaaaaa ttaattttaa aaaagctacc tgtataaata taaatatata
     7381 tatttaaaga caaggttttg atactttttt tttaaaaaac aaaaactaca agagaagact
     7441 gtacaaacca cgggctttta aaatagcatt ttgctctcta caagctgtta atgtcagggg
     7501 tgaggggtga gggactggtt tgcaaacaca ctatccaaat ggatttgctt gttttgtcaa
     7561 gccaccctcc aaattaccat atttggtgta atagtagggc atgtaaagtt attgggtccc
     7621 attaaccatt tctgctcttg tcatgtcatt ccgggttccg ttagctcccg tactcggcaa
     7681 tccagcttct tccagaggca gaggggctga aggaagtgtg ctccatttca ctagctgtac
     7741 tgacatcatc cacatgtgga catttgtaat atcagtacac tatttctaga gagattaaat
     7801 tcatttttta aaatctg
//
