LOCUS       XM_011240454            7820 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus low density lipoprotein receptor-related
            protein 8, apolipoprotein e receptor (Lrp8), transcript variant X1,
            mRNA.
ACCESSION   XM_011240454
VERSION     XM_011240454.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_011240454.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7820
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..7820
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /note="low density lipoprotein receptor-related protein 8,
                     apolipoprotein e receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 5 ESTs, 3543 long SRA reads, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 20 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
     CDS             259..3291
                     /gene="Lrp8"
                     /gene_synonym="4932703M08Rik; ApoER2; Lr8b"
                     /codon_start=1
                     /product="low-density lipoprotein receptor-related protein
                     8 isoform X1"
                     /protein_id="XP_011238756.1"
                     /db_xref="GeneID:16975"
                     /db_xref="MGI:MGI:1340044"
                     /translation="MGRPELGALRPLALLLLLLLQLQHLSAADPLPGGQGPVKECEED
                     QFRCRNERCIPLVWRCDEDNDCSDNSDEDDCPKRTCADSDFTCDNGHCIPERWKCDGE
                     EECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTL
                     CAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERW
                     VCDRQFDCEDRSDEAAELCGRAGQGTTATPAACAPTAQFTCRSGECIHLGWRCDGDRD
                     CKDKSDEADCSAPGPCRENEFQCGDGTCVLAIKRCNQERDCPDGSDEAGCLQESTCEG
                     PRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCVAPSFPGNRRHPRGLNECLHNNG
                     GCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHP
                     GYEMDTLTKNCKAVAGKSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVAT
                     NRIYWCDLSYRKIYSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVHKHIYWTDSGNK
                     TISVATTDGRRRCTLFSRELSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQT
                     LVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVA
                     VFEDKVFWTDLENEAIFSANRLNGLEIAILAENLNNPHDIVIFHELKQPKAADACDLS
                     AQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASAMT
                     RTVPATTRAPGTTIHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHS
                     QHYGNEGSQMGSTVTAAVIGVIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYR
                     KTTEEEEEDELHIGRTAQIGHVYPAAISNYDRPLWAEPCLGETRDLEDPAPALKELFV
                     LPGEPRSQLHQLPKNPLSELPVVKCKRVALSLEDDGLP"
ORIGIN      
        1 gaggcggcgg cgggagggag cgcgcgcgcc ggcggcggct gcccagggcc ggggccgcgc
       61 gcccagcctg agcccgcccc gccgccgagc gtcaccgaac ctgcttgaaa tgcagccggg
      121 gagccggggc gggcggcagc ggtggtggtg gcggcggcgg cagcggcagc cccggcgccg
      181 cggcaaggac ttggcgggct gaggcgcggc ggcggcgcgg gggtctcggg gcgcggcggc
      241 cggagccccg ggcccgctat gggccgccca gaactgggcg cgctccggcc gctggcgctg
      301 ttgctgttgc tgctgctgca gcttcagcat ctctccgcag cggatccgct gccgggcggc
      361 caagggccag tcaaggagtg tgaagaggac cagtttcggt gtcggaacga gcgctgcatt
      421 cccttggtgt ggagatgcga tgaggacaac gactgctcgg acaacagcga cgaggacgac
      481 tgccccaaga ggacctgcgc ggacagcgac ttcacctgtg acaatggcca ctgcatccca
      541 gagcggtgga agtgcgacgg cgaggaggag tgtcccgatg gctctgacga atcgaaggcc
      601 acgtgctcca gtgaagagtg tcctgccgag aagttaagct gcggacccac cagccacaag
      661 tgtgtgcctg cctcatggcg ctgcgacgga gagaaggact gtgagggtgg tgctgacgag
      721 gccggctgtc ccaccttgtg cgccccgcac gagttccagt gcagcaaccg ctcctgcctg
      781 gcctctgtgt tcgtgtgcga tggtgacgat gactgcggcg acggcagcga cgagcgtggc
      841 tgctcggacc cggcctgccc gccccgcgag ttccgctgtg gaggaggcgg cacctgcatc
      901 cctgagcgct gggtctgcga ccgccagttc gactgcgagg accgctcgga tgaggcggcc
      961 gagctctgcg ggcgagcggg ccaggggacc acggccacgc cagcagcctg cgccccgacc
     1021 gcccagttca cctgccgcag cggcgagtgc atacacctgg gctggcgctg cgacggcgac
     1081 cgcgactgca aggacaagtc tgacgaggcc gactgctcag caccaggacc ctgccgcgag
     1141 aatgagttcc agtgtgggga tgggacttgc gttcttgcca tcaaacggtg caaccaggag
     1201 cgggactgcc cggacgggag tgacgaagcg ggctgccttc aggagtcaac ttgtgagggt
     1261 ccccgcagat ttcagtgtaa gagtggcgag tgcgtggacg gcgggaaagt gtgtgatgat
     1321 cagagggact gccgggactg gtcggatgag cctcagaaag tgtgtgttgc accatcattc
     1381 ccgggaaaca ggaggcatcc cagggggcta aatgagtgtc tgcacaataa cggcggctgt
     1441 tcccacatct gcactgacct caagatcggc tttgagtgca cgtgcccagc aggcttccag
     1501 ctcttggacc agaagacctg tggtgacatt gatgaatgcc aggacccgga tgcctgcagc
     1561 caaatctgcg tgaattacaa gggctacttt aagtgtgaat gccaccctgg ctatgagatg
     1621 gatacactga ccaagaactg caaagctgta gccggcaaga gcccatctct gatcttcacg
     1681 aaccgacacg aggtgcggag gatagacctg gtgaagcggg actactcgcg cctcatcccc
     1741 atgctcaaga atgtcgtggc gctggacgtg gaagtagcca ccaatcgcat atactggtgc
     1801 gacctctcct accgcaagat ctacagcgcc cacatggaca aggccagcat cccggacgag
     1861 caggtggtcc tcattgatga gcagctgcac tccccggagg gcctggcggt ggactgggtc
     1921 cataagcaca tctactggac agactcaggc aataagacca tctcagtggc cacaaccgat
     1981 ggacgccgcc gctgtactct cttcagccgt gagctcagtg agccccgagc cattgccgtt
     2041 gaccccctgc gagggttcat gtactggtct gactggggtt tccaggcaaa gattgagaag
     2101 gctgggctca atggtgcaga ccggcaaaca ctggtttcag acaacattga atggcccaat
     2161 ggaatcaccc tggacttgct gagccagcgt ttgtactggg tggactccaa gctgcaccaa
     2221 ctatccagca ttgacttcaa tggaggcaac agaaagatgc tgatcttctc cactgacttc
     2281 ctgagtcacc cttttggggt tgctgtattt gaggacaagg tattctggac agacctggag
     2341 aatgaggcca ttttcagcgc aaatcggctc aatggcctgg aaatcgccat cctggccgag
     2401 aacctcaata acccacatga cattgtaatc ttccacgagc tgaagcagcc aaaggctgca
     2461 gatgcctgtg acctgagtgc ccagcccaac ggcggctgtg aatacctgtg ccttcctgct
     2521 cctcaaatct ccagccactc ccccaagtac acgtgtgcct gtcctgacac gatgtggctg
     2581 ggcccagaca tgaagagatg ctaccgagca cctcagtcta cctcaactac aaccttagcc
     2641 tctgccatga caaggacagt acctgctacc acaagagctc ctgggacaac catccacgac
     2701 cctacctacc agaaccatag cacagagacg ccaagccaga cagctgccgc ccctcactcg
     2761 gttaacgtcc ctagggctcc cagcaccagc ccatccaccc cgagccctgc taccagcaac
     2821 cactcccagc attatgggaa tgaaggcagc cagatgggct caacagtcac cgctgctgtc
     2881 attggggtca tcgtgcccat agtggtaata gccctgctat gtatgagtgg gtacctcatc
     2941 tggaggaact ggaagcggaa gaacaccaag agcatgaatt tcgacaaccc agtgtacagg
     3001 aaaacgacag aagaggaaga ggaagatgag cttcacatag ggaggacagc tcagattggc
     3061 cacgtctacc ccgcagcaat cagcaactat gatcgcccac tgtgggcaga gccctgtctt
     3121 ggggagacca gagacctgga agacccagcc cctgccctca aggagctttt tgtcttgccg
     3181 ggagaaccaa ggtcacagct tcaccaactc ccgaagaacc ctctttccga gctgcctgtc
     3241 gtcaagtgca agcgagtggc attaagtctt gaagatgatg gactgccctg aggatgggcc
     3301 cacccacttc gtgcctcatg gagttcagtc ctatgcacta ctctctctgg atggtgtgtg
     3361 attggatgag tgccatttct atatatgggt ctgtgtgagt gtgtgtgtgt gtgtgtgtga
     3421 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtat gtgacttttt
     3481 ttaaatttat gttgcggaaa ggtaaccaca aagttatgat gaactgcaaa catccaaagg
     3541 atgtgaaagt ttttatatgt ataatgtttt atacactttt taactggttg cactacccgt
     3601 gaagaattca tgggacagcc actgctgagt gactaacatg atgcacataa ccaaacgggg
     3661 ccaatggtac aaacttcact catcatttga atacagtatt tacagaggat gtttgagttg
     3721 agagcttttt taggtttgag gggcttgatt tttttgtaaa taaaattatg ctttgtggct
     3781 atccatcaac ataagtataa aaagaaagaa cgcttcaacc cccttcccca tttagattat
     3841 ttattaacat atttcgaaag taaggttagc tctataaata atttagagag gtgagagtat
     3901 ttatttttgg tatggctggc tcactgcaca gactctgtgt ttatgtgtgt gtgtctgtgt
     3961 gagagaagaa aaatctgtag agaagaggca cgcttatgac tattgttcaa atacataaaa
     4021 acagttattt taaaacagtc cacaagaggg gtgtctagtt ttcagagaca cttcagaaac
     4081 tttgctcaga aaacagatgc tacagtttgt gcaggcatgc ggtaggaaag gtagatcacc
     4141 tctggctact cctgaggccc tgctgagcca gcaaaatgct ttccagttcc tctttggctc
     4201 tcacgatgcc cacctaggct ttctggccag tgtactgaac agtgctacaa gccctcagga
     4261 gctcaagata gcagagtcct tctttcaaag cccagcttag tgaggacttg ggtcaacttc
     4321 agtaagcttc ctctgaagca actgaaggcc gagcctttag agcaaccatt gtcaaccttt
     4381 gtgggtcgcc taagagcatc gcaaaccaga tatttacatt atgattcata acagtgacaa
     4441 tcacagttat gaggtagaaa ggaaagggat tttatggttg ggggttagtc caacaagagg
     4501 gacagtgtta atgcttctga agcatcagga aggttgaaag ccactgctct agagccaagt
     4561 gagtgcatgt ctagggttcc catgtttaca gtaaggaccg gctcaggcac tgaccctctg
     4621 agtcacgtga atgaggacga agaatttgga ataggtttgg ttacatctat ttctcatccc
     4681 cttattttcc accatttaaa aataataaac atgtttctta ccaccgtatg ttcatatgga
     4741 taagactaag tccaaaaagg tgactacatc caaatttata tttcggggaa ataccatgag
     4801 ataattatag catactgggc atgtgtccac acacggattg gtttcactgc tttataaata
     4861 aaaggaacaa ctctgggtat ttgtatagaa ttttcttcat atgtaacatc tttccatttc
     4921 ctgagccttg ggggtggggt gggagaatgc cacttgctgt ctgtgaagtc cactgttgga
     4981 aacataattc catagtccca gaaggaattc agtccccacc aacttactct ttcaaagtgt
     5041 ggtcttcccg cgactctgca gctctgcagt tcactccagc tgaacgacca gggacaagta
     5101 caacacagga gtttggctta agtggcagca gactaatatc taaagttgac ataactgaaa
     5161 tctgacattt gaggcatatg tctccgcgtc cccacacacc ggcttgagtg gctcacctgc
     5221 ttgatgtcct ttcaacttcc ggggagaccg tctggagacc tgtcatcctg tcatcctgtt
     5281 cctaggagct tgctctatgt cactcatgtt ttcctaacct ttaaaaaatg gctgtgttcc
     5341 aagcctggcc attatgtctg acaatgcacg tgttgatggt cttgagatat acagtgacta
     5401 aatgcagctg acccctgacc cattccaaac agtctcaagg acaggcagct gagtcccctg
     5461 cagctcgcct gtcactgttc atccaggaat ggagaggaga aatcaagttt actaaagaaa
     5521 aaggttagaa gtgaaatcat caaaatttac acaagatagg cagggttttt ccctttaatc
     5581 tgcctccaag gaaactgaag cagtgatagt gtatagtttc tgaacaaacg ttcatagcct
     5641 agccttcaca acaaggctga aacataccgt ctagggtttc cgaaagatga aagaattcat
     5701 atcagaaata ccatgtttcc tgaatgtgcc acagctgcag tctaaaagca gcctacagta
     5761 aacagatggg caaatccagg gacggccgga gagcggaagc actctgaggg accagaccga
     5821 cctccttcta tccttggaaa ctttttgagc ctcattctga ggtgtaattc agacttctgt
     5881 tgcctttcgc ctctgcctat gtatccacag ccaataacag ctgaaaggaa actcagtaat
     5941 aaaccaaaag gacagaaaat tcaacaaacg ttacttatta aaacgaagcc aaccccttcc
     6001 ttctctagaa gacaactctg agcagcctga acaaggtctc agacctgcat cctctccaca
     6061 gctatctgcc cagtggattg aaggcactaa cagaaacgac tttcctgaaa caagaaacta
     6121 cagctttgtt tactcttcag aatgtgtgta tgtgtgtgca cagagggaca ggatgagacg
     6181 gcttctgaca aggagtaaga agaatgagac aggatttaaa ctgatgtcag tgaacactgt
     6241 tgaagccctc cagttatcct catgtcttag taacatactc agagtattca ctcgctgctg
     6301 tgtgccaggc tttgcagaca ttgcaggtca attcaacagt tttcaccctt tccaaactca
     6361 cagcagtaca tatggataca aaaagaaaaa aaaattttcc catagatttc acctagacta
     6421 ctcccaaggc acaacaaaag agatgggcca ttttacctga agaggtggaa ataggtctac
     6481 ataggaatga cccaaagcaa tgtcttaaaa cttaaaaagt ggtgttcagg ctgcttctat
     6541 gagaagaggc tgggctcaga ctgggagtga atcagcagca ggaatttcaa ggaaaacatg
     6601 gagttcctta cacctggaat aaagaacttt agcagggttg gcaagatgtg aaactggatg
     6661 gaaagacaag ttcaacacaa gcactttata aaatagtctg atgtaagtaa gcagacattt
     6721 gtttggtcgt cggttcctgt gtgcaaggca tcatgggaaa ctccctgcca gcacttggca
     6781 ggcattattc cacctcaagc tttccagaga ccacagggaa atgactgttt tctttatttg
     6841 agccagaggt tttgatatgg ttcctgaagg ctaacagaag ggcggtgggc ttgtcaacag
     6901 aagcacgcca tgttgccgag cacctgtgag gtcctcacgt gggaggaaga gaacaaggtg
     6961 gttaagatag agaatctgga gagggtaccc caatcacact acagtcgggt gctactgggt
     7021 ggaggagaaa accatcctaa ccccacagca ctgcaaagac gctcctgtcc cgccacactc
     7081 ccaccatcac gaacatcagt aagtcagcag tttcagattc tgccatttcc ttccccataa
     7141 aagcatgaag atagggagtc ggtgtcctta cgctttattt ttagggtatt tgggagtttc
     7201 caggatgtga agaagttagg tggaggaaat tacggcttca atttttttca gttaactaca
     7261 ggacgcttca ttcaggccgg gcaccatgtg cacagtctta agaagcagca ggaactgcat
     7321 ttgcaaacac gtgttgtaaa aaattaattt taaaaaagct acctgtataa atataaatat
     7381 atatatttaa agacaaggtt ttgatacttt ttttttaaaa aacaaaaact acaagagaag
     7441 actgtacaaa ccacgggctt ttaaaatagc attttgctct ctacaagctg ttaatgtcag
     7501 gggtgagggg tgagggactg gtttgcaaac acactatcca aatggatttg cttgttttgt
     7561 caagccaccc tccaaattac catatttggt gtaatagtag ggcatgtaaa gttattgggt
     7621 cccattaacc atttctgctc ttgtcatgtc attccgggtt ccgttagctc ccgtactcgg
     7681 caatccagct tcttccagag gcagaggggc tgaaggaagt gtgctccatt tcactagctg
     7741 tactgacatc atccacatgt ggacatttgt aatatcagta cactatttct agagagatta
     7801 aattcatttt ttaaaatctg
//
