LOCUS       NM_028275                911 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus leucine rich melanocyte differentiation associated
            (Lrmda), mRNA.
ACCESSION   NM_028275 XM_886604 XM_908132
VERSION     NM_028275.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 911)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 911)
  AUTHORS   Guo,Y.Y., Gao,Y., Hu,Y.R., Zhao,Y., Jiang,D., Wang,Y., Zhang,Y.,
            Gan,H., Xie,C., Liu,Z., Zhong,B., Zhang,Z.D. and Yao,J.
  TITLE     The Transient Receptor Potential Vanilloid 2 (TRPV2) Channel
            Facilitates Virus Infection Through the Ca2+ -LRMDA Axis in Myeloid
            Cells
  JOURNAL   Adv Sci (Weinh) 9 (34), e2202857 (2022)
   PUBMED   36261399
  REMARK    GeneRIF: The Transient Receptor Potential Vanilloid 2 (TRPV2)
            Channel Facilitates Virus Infection Through the Ca[2+] -LRMDA Axis
            in Myeloid Cells.
REFERENCE   3  (bases 1 to 911)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 911)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK007175.1 and BY516672.1.
            
            On or before Apr 10, 2009 this sequence version replaced
            XM_908132.2, XM_886604.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007175.1, SRR5189685.217974.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-908               AK007175.1         5-912
            909-911             BY516672.1         424-426
FEATURES             Location/Qualifiers
     source          1..911
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 12.03 cM"
     gene            1..911
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /note="leucine rich melanocyte differentiation associated"
                     /db_xref="GeneID:76633"
                     /db_xref="MGI:MGI:1923883"
     exon            1..197
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..857
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /note="leucine-rich repeat-containing protein C10orf11
                     homolog"
                     /codon_start=1
                     /product="leucine-rich melanocyte
                     differentiation-associated protein"
                     /protein_id="NP_082551.1"
                     /db_xref="CCDS:CCDS49415.1"
                     /db_xref="GeneID:76633"
                     /db_xref="MGI:MGI:1923883"
                     /translation="MAGLMVSGTQVSYVGQSCREIPEHLGRDFGHFAKRLDLSFNLLR
                     SLEGLSAFRSLEELILDNNLLGDDLVLPGLPHLHTLTLNKNQITDLEYLLDHLAEVTP
                     SLEYLSLLGNVACPNELVNLEKDEEDYKRYRCFVLHKLPKLKFLDAQKVTRQEREEAL
                     VRGAFMKVVKPKASSEEEKAAAPENQPQYTPLPSGSRDLTSHRGVLGKGRYFYYGRNS
                     EGNRFIRDDQL"
     exon            198..298
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            299..425
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            426..565
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            566..683
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            684..777
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            778..911
                     /gene="Lrmda"
                     /gene_synonym="1700112E06Rik; 2700009F18Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcacgtgc accgggttga gccagccagc ggcggcagcg ctgctgcgca cagttcttgg
       61 tggccgaccg gagtctaggg cttccgttgg tcagctgacc tcccagtgcg gaactgcgcc
      121 gcccgccacc ctgctcagtg ccgcccgcct gctgggttcc tgccacaatg gctgggctca
      181 tggtcagtgg aactcaagtg tcctacgtag gccagtcctg cagagaaatt ccagagcacc
      241 tgggccggga ctttggacat tttgcaaaga gacttgacct gagcttcaac ctcttgaggt
      301 cactggaagg actgagtgca ttcaggagcc tggaggagct cattttagac aacaatctgc
      361 tcggagacga cctcgtgttg ccagggttac cccacttgca caccttaacc ctcaacaaga
      421 accaaattac cgacttggag tacctccttg atcacctggc agaagtgaca ccatccttag
      481 agtacctcag cctcctggga aacgtggcat gtcccaatga gctggtcaac ttggagaagg
      541 atgaggaaga ctataagaga tacaggtgct ttgttctgca caagctgccc aagttgaagt
      601 ttctggatgc ccagaaagtc accagacaag aacgggagga ggcattggtc agaggggcct
      661 tcatgaaggt ggtgaaaccc aaggcttcca gtgaggagga gaaggctgct gctcctgaga
      721 accagcccca gtacacaccc ttgccttctg gatccagaga tctcaccagt catcgaggcg
      781 tcctcgggaa aggtcgctat ttttactatg gaagaaattc agagggtaac aggtttatcc
      841 gagatgatca gctctgaagc taaactctgc acgccttagc ctgtttcatg acaataaagt
      901 ggaaaagcaa g
//
