LOCUS       NM_173418               2818 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus leucine-rich repeat, immunoglobulin-like and
            transmembrane domains 2 (Lrit2), transcript variant 1, mRNA.
ACCESSION   NM_173418
VERSION     NM_173418.5
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2818)
  AUTHORS   Ueno A, Omori Y, Sugita Y, Watanabe S, Chaya T, Kozuka T, Kon T,
            Yoshida S, Matsushita K, Kuwahara R, Kajimura N, Okada Y and
            Furukawa T.
  TITLE     Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse
            Formation in Cone Photoreceptor Cells and Visual Acuity
  JOURNAL   Cell Rep 22 (13), 3548-3561 (2018)
   PUBMED   29590622
  REMARK    GeneRIF: Lrit2 is dispensable for photoreceptor synapse formation
REFERENCE   2  (bases 1 to 2818)
  AUTHORS   Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y
            and Yoshida Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2818)
  AUTHORS   Homma S, Shimada T, Hikake T and Yaginuma H.
  TITLE     Expression pattern of LRR and Ig domain-containing protein (LRRIG
            protein) in the early mouse embryo
  JOURNAL   Gene Expr Patterns 9 (1), 1-26 (2009)
   PUBMED   18848646
REFERENCE   4  (bases 1 to 2818)
  AUTHORS   Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber
            G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong
            WH and Cepko CL.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158525.2.
            
            On Sep 1, 2022 this sequence version replaced NM_173418.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057628.1, AK044383.1 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-165               AC158525.2         12423-12587         c
            166-947             AC158525.2         11350-12131         c
            948-2818            AC158525.2         6864-8734           c
FEATURES             Location/Qualifiers
     source          1..2818
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 21.29 cM"
     gene            1..2818
                     /gene="Lrit2"
                     /gene_synonym="A930010E21Rik; Lrrc22"
                     /note="leucine-rich repeat, immunoglobulin-like and
                     transmembrane domains 2"
                     /db_xref="GeneID:239038"
                     /db_xref="MGI:MGI:2444885"
     exon            1..165
                     /gene="Lrit2"
                     /gene_synonym="A930010E21Rik; Lrrc22"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1705
                     /gene="Lrit2"
                     /gene_synonym="A930010E21Rik; Lrrc22"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; leucine-rich repeat, immunoglobulin-like domain
                     and transmembrane domain-containing protein 2;
                     leucine-rich repeat-containing protein 22"
                     /codon_start=1
                     /product="leucine-rich repeat, immunoglobulin-like domain
                     and transmembrane domain-containing protein 2 isoform 1
                     precursor"
                     /protein_id="NP_775594.1"
                     /db_xref="CCDS:CCDS26951.1"
                     /db_xref="GeneID:239038"
                     /db_xref="MGI:MGI:2444885"
                     /translation="MAFVFYCFLQVLVSWVIHAVQPFCLPECTCSEESFGRSLQCMSM
                     SLGKIPDNFPEELKQVRIENSPLFELSQGFFTNMSSLEYLWLNFNNVTVIHLGALEDL
                     PELRELRLEGNKLRSVPWTAFRATPLLRVLDLKHNRIDSVPELALQFLTNLIYLDISS
                     NRLTVVSKGVFLNWPAYQKRQQLGCGAEFLSNMVLSLHNNPWLCDCRLRGLAQFVKSV
                     GPPFILVNSYLVCQGPVSKAGQLLHETELGVCMKPTISTPSVNVTIQVGKNVTLQCFA
                     QASPSPTIAWKYPLSTWREFDVLASPIAEGIILSQLVIPAAQLVDGGNYTCMAFNSIG
                     RSSLVILLYVQPAQAMPGLHFLSTSSEVSAYVDLRVVKQTVHGILLQWLTVTNLAEEQ
                     WFTLYITSDEALRKKVVHIGPGINTYAVDDLLPATKYKACLSLRNQPPSQGQCVVFVT
                     GKDSGGLEGREHLLHVTVVLCAVLLALPVGAYVWVSQGPYNFSEWCWRRCPLHRKTLR
                     CPQAVPQCKDNSFKDPSGVYEDGESHRVMEEDEEVEKEGIS"
     exon            166..947
                     /gene="Lrit2"
                     /gene_synonym="A930010E21Rik; Lrrc22"
                     /inference="alignment:Splign:2.1.0"
     exon            948..2818
                     /gene="Lrit2"
                     /gene_synonym="A930010E21Rik; Lrrc22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaagctgag accataccta cccaaaccac acaaggtatt tgcctacaga taaatatggc
       61 ttttgttttt tactgtttct tgcaagttct ggtctcttgg gttatacatg cagtgcagcc
      121 gttctgtctg ccagagtgta cctgttcaga ggagagtttt ggcaggagcc ttcagtgcat
      181 gtctatgtct ttgggaaaga ttccagacaa ctttcccgaa gaactcaagc aagtgagaat
      241 tgaaaactca cccttatttg aactttccca ggggtttttc accaacatga gcagtttgga
      301 atacctttgg ctcaacttta acaatgtcac tgtgatccac ctaggcgccc tggaggacct
      361 gccagagctg agagagctga gactagaggg gaacaaactc cgttcagtac catggacagc
      421 gttccgcgcc acccctctcc tgcgggtttt ggatctcaaa cacaaccgga ttgattctgt
      481 cccagaactg gctcttcagt tcctaaccaa cctgatatac cttgacatat cctccaacag
      541 gttgacagtt gtatccaagg gtgtcttctt gaactggcca gcctatcaga aacggcaaca
      601 gcttggttgt ggagctgagt ttctttccaa tatggtattg tcgctgcaca ataatccttg
      661 gttgtgcgac tgccgattaa ggggacttgc tcagtttgtc aagtccgttg gtcccccttt
      721 catactggtg aattcgtacc tggtatgcca gggtcctgtc tctaaggcag ggcagctttt
      781 acatgagact gagctcggag tttgtatgaa gccaactatt tcaaccccta gtgtcaatgt
      841 cactatccag gtaggaaaga acgtgactct gcaatgtttt gcacaagcca gtccctcacc
      901 aaccattgca tggaagtatc ccctgagcac gtggagagaa tttgatgtgt tggcctcgcc
      961 aattgcagaa ggtatcattc tgtctcagct tgtcatccca gcagctcaac tggtagatgg
     1021 cggtaattat acctgcatgg ccttcaactc catcggcagg agctcccttg tcatcttact
     1081 ctatgtccag cctgcacagg ccatgcctgg attgcatttc ctttccacct cttcagaggt
     1141 cagtgcctat gttgacctac gagtggtcaa gcagacagtg catggcatct tgctgcagtg
     1201 gctcacagtg accaaccttg ctgaggaaca atggttcacc ctctatatta catctgatga
     1261 agctctcagg aagaaggtgg tccacatagg ccctggaatc aacacatacg ccgtggatga
     1321 ccttctccct gctacaaaat ataaagcatg tctcagcctg aggaatcagc ctccaagcca
     1381 gggccagtgt gtggtctttg tgacaggcaa agacagtggt gggctagagg gtcgtgagca
     1441 cctcttgcat gtcactgtag tcttgtgtgc tgtgctcctg gcactgcctg tgggtgctta
     1501 tgtctgggta tcccagggtc catacaactt cagtgagtgg tgttggcgcc gttgtcctct
     1561 tcacaggaaa accctaagat gcccacaagc agtaccacag tgcaaggata actctttcaa
     1621 agacccttca ggtgtctatg aggatggtga gagtcacaga gtcatggagg aggatgagga
     1681 ggtagaaaag gagggtatca gttaacaacc caccatggca tggaaatgaa tagacctcta
     1741 gttcctgaat ccaacttccc atgacagcac aacttggttc catccattta tcaagcaagg
     1801 atttcttgag cagccactgt gttctaatta aggtatttga tgaagagaat tcagaaataa
     1861 gaaaggggac acagtattta tcttcataaa gctaaagcca atagagctct gacctattaa
     1921 actatgcctg atagtggcta gaaaataaca aatattactc ttatatatgc ctagccctat
     1981 aaggtttaca cagaacatct catatgcatt atcctgcaaa gtataagatt tattgtagat
     2041 aaagaaactt gatctcataa aggtctatca agtttctgtc catcacttat ctagccagtg
     2101 gcagggcact ggtctacaga ggatggattc tgctgtttta caaataagcc aacaactggc
     2161 cttactacaa gcactgtgct catgtggatg cattgagaat caatgacagt tgaaataaca
     2221 ttttaaaaat tggtggcaac actcatattg aaattaatca cccttcatta ctttgggttc
     2281 ttatattttt ttcttcaagg aaaaagaatt aaacctttta aaatggaaat tccctgtgtg
     2341 tgctggacag ttttatttca agtcgacaca agccgaagtc atatgatagg aggaaaaaaa
     2401 aacttcaatc aaaactgcct tcacaagatt ggggctgtag gacatttttt aaattagtta
     2461 ttgagggggg gttggccctg cccactgtgg gtggtgccat tcccgggctg gtggtcctag
     2521 gttctataag aaagcagact gagcaagcca ttttgcagca cccctccatg gcctctgcat
     2581 cagttcctgg ctccaggttc cttccctgtt cgagtttctg tcctagcttc tttcaacaat
     2641 gtattgtgac acagaagtgt aggccaaata aaccctttcc cttccaactt cctttttagt
     2701 catggtgttt cagcatagca atgaaaatct aattaagtca ctattgtacc aaaagtagaa
     2761 aaaaattaca ttcctcccct ctgataactt caataaattt tagcattttc tagtctta
//
