LOCUS       NM_027599               2782 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus lysophosphatidylcholine acyltransferase 2B (Lpcat2b),
            mRNA.
ACCESSION   NM_027599 XM_132188
VERSION     NM_027599.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2782)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2782)
  AUTHORS   Saul,M.C., Stevenson,S.A., Zhao,C., Driessen,T.M., Eisinger,B.E.
            and Gammie,S.C.
  TITLE     Genomic variants in an inbred mouse model predict mania-like
            behaviors
  JOURNAL   PLoS One 13 (5), e0197624 (2018)
   PUBMED   29768498
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2782)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY714455.1, BB572733.1, AK029548.1 and AV255931.2.
            
            On Nov 16, 2011 this sequence version replaced NM_027599.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AA497987.1, BB572733.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-414               BY714455.1         2-415
            415-462             BB572733.1         13-60
            463-2590            AK029548.1         465-2592
            2591-2782           AV255931.2         813-1004
FEATURES             Location/Qualifiers
     source          1..2782
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 52.23 cM"
     gene            1..2782
                     /gene="Lpcat2b"
                     /gene_synonym="4921521K07Rik; Aytl1b"
                     /note="lysophosphatidylcholine acyltransferase 2B"
                     /db_xref="GeneID:70902"
                     /db_xref="MGI:MGI:1918152"
     exon            1..430
                     /gene="Lpcat2b"
                     /gene_synonym="4921521K07Rik; Aytl1b"
                     /inference="alignment:Splign:2.1.0"
     exon            431..2782
                     /gene="Lpcat2b"
                     /gene_synonym="4921521K07Rik; Aytl1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             550..2100
                     /gene="Lpcat2b"
                     /gene_synonym="4921521K07Rik; Aytl1b"
                     /note="lysophosphatidylcholine acyltransferase 2-B;
                     acyltransferase-like 1-B; acyltransferase like 1B"
                     /codon_start=1
                     /product="lysophosphatidylcholine acyltransferase 2B"
                     /protein_id="NP_081875.1"
                     /db_xref="CCDS:CCDS19502.1"
                     /db_xref="GeneID:70902"
                     /db_xref="MGI:MGI:1918152"
                     /translation="MAHQNQHQDTIDSTEVEVWDSRTAQEVNKSLYPPAVDSPFTLNT
                     HLSAWRWACTIILGTVLVPVRVSCIVFLLILLWPVAVLSAINLPTQPTKPIRRWRKHL
                     IKSALVFLFRLGFFFAGFLVKVKGKKATREEAPIFVSAPHSTFFDAIAVVVAGLPSVV
                     SDSQLARVPLAGKCILVTQPVLVKREDPNSRKTTRNEILRRVKSKMKWPQILIFPEGL
                     CTNRSCLVTFKLGAFSPGVPVQPVLLRYPNSLDTVTWTWNGFSGFQVCMLTLSQLFTR
                     VEVEFMPVYIPSEEEKKDPILFANTVRIKMANALKLPVTDHSLEDCKLMISAGALQLP
                     MEAGLVEFTKISQKLKLDWDNIHKHLDQYASFAVSSKGGKIGIEAFSRYLKLPISEPL
                     RQLFSLFDRNQDGTIDFREYVIGLTVLCNPSNTEKILQMSFKLFDLDEDGYVTERELT
                     TMLQAAFGVPDLDVSTLFQQMAGKDSDQVSYRTFRRFALKHPAYAKLFHSYIDLQAAY
                     IYSLPREV"
     regulatory      2177..2182
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lpcat2b"
                     /gene_synonym="4921521K07Rik; Aytl1b"
                     /note="hexamer: AATAAA"
     polyA_site      2202
                     /gene="Lpcat2b"
                     /gene_synonym="4921521K07Rik; Aytl1b"
                     /note="major polyA site"
ORIGIN      
        1 gactggagtc ttggagtctt gtaacaaaca tgcatggtag ggagtatcgc caacttaaag
       61 atgtgagaac aagttttaac atgtaacttt accaattccc cttgtgtaat gttggcacct
      121 ggaagaggtc ttccacggag atccatcttg cttaccaagc tttggtaccc atagctccct
      181 cctcttgtag tagggctaac ccgatacatg tcaatagatg tgaactcagg gacctaaaca
      241 atcactttca tttcgggaaa aggaattcag attaccagtt agtgaacaca gcaggaatcc
      301 tcagtgcagc atggtccgga tggtgactgc tcccagatcc agaagagagc ctagttcaca
      361 ctaactggct ctatgacgtc tcgaggactg caggaaacaa gggaatcgtc ctggaaaccg
      421 tgctgacaca gtagtgcatc atttcctatt aaccaacaat tagctgtaag ggcgctaatt
      481 acatgcaaac acggaaatag cccttggatg tggagaaagg aatagccata acgctgagaa
      541 gccggcttca tggctcatca gaaccagcac caggatacca tagactccac agaggtggag
      601 gtgtgggaca gcaggactgc gcaggaggtg aacaagtcct tatatcctcc ggcagtggac
      661 agtcccttca ctctcaacac tcacctgagt gcttggcgct gggcctgcac catcatcctg
      721 gggactgtgc tggtacccgt gcgggtgtcc tgcattgtct tcctcctcat ccttctctgg
      781 ccagtggccg tactctccgc cattaacttg cctactcaac ctaccaaacc cataaggaga
      841 tggaggaaac atctgataaa gtcggccctg gtattcttgt ttcgtttggg gttctttttt
      901 gctgggttcc tggttaaggt caaagggaaa aaggctacca gagaggaggc ccccatcttt
      961 gtctccgcac cacactccac cttctttgat gcaatcgccg ttgttgtggc ggggctccct
     1021 tcggtggtct ctgatagtca gcttgcgagg gtcccattgg ctgggaaatg catcctggta
     1081 actcagcctg tgcttgtgaa acgagaagac ccgaattcta gaaagactac ccggaatgaa
     1141 atcctcagac gagtgaaatc taaaatgaag tggccacaga ttctgatttt tccggaagga
     1201 ttgtgcacca accgctcctg tctcgtcact tttaaactag gagccttctc cccaggtgtc
     1261 cctgtgcagc cagtgctgct taggtacccc aacagcctgg acacagtgac ctggacttgg
     1321 aatgggttct caggcttcca ggtatgtatg cttactctga gtcagctctt cactagagtg
     1381 gaagtcgagt tcatgcctgt ttatatccca agtgaagaag aaaagaaaga ccccatcctt
     1441 tttgccaaca cagtccgaat caagatggca aacgctttga agctgcctgt aaccgatcac
     1501 agcttggaag actgtaaact gatgatatct gcgggtgccc ttcaactacc catggaagct
     1561 ggcttggtgg aatttacaaa aatcagtcag aaattgaaat tagattggga caacatccac
     1621 aagcacttgg accaatatgc ttcgtttgcg gtctcctcaa aaggaggcaa gattggaatt
     1681 gaagcattct cacgttattt aaaactccca atttcagagc ccttgagaca gcttttctct
     1741 ctctttgaca ggaatcagga tggcaccata gacttccgag agtatgtgat aggtctaact
     1801 gtcctgtgca acccatccaa tacggagaag attctgcaaa tgtcatttaa actttttgat
     1861 cttgatgagg atggttatgt aacagaacgg gagttgacaa ctatgcttca ggcagctttc
     1921 ggagtgccag acctagatgt ttccacactc ttccagcaga tggctggcaa ggattcagat
     1981 caggtttcat acagaacttt tcggaggttt gccctgaagc atccagcata tgccaaatta
     2041 tttcattcat acatagatct ccaggcagcc tatatatact cattaccaag agaagtataa
     2101 acatttccct aatattaaga tgttcaaggc atccttggaa acaggaaaag aacttttagg
     2161 tggaaatgat gaactaaata aaaattatcc tttgaggaaa aactcagtgg tttttactct
     2221 aagtaacatg gatactgtct tggaaaaagc aacttgggta agggcttcca tctttgagga
     2281 aagccaggcc aagcactcaa gcagaagtag agatggggac catggagggg tgctgcttac
     2341 tggcttgctc cccgtggctc actcagcata cttatacaat ccaggaccat ttgcccaggg
     2401 aaggcaccat tcactatgag ctaagccctc tcacatcagt attcaagaaa atgtaccact
     2461 gacttgtcca caggctggtc tgatggagac aattcttcag ttgtggtcct ttcttctcaa
     2521 atggccctag cttgtgtcat gttgacagaa actaatacac acagatatta tatgtaaaat
     2581 atgcttgagg aattataatg cctttccctc ccttaagata atgttcattg ggcacaatgg
     2641 catatgcctg tattcccatc cacccagtaa ataagaagca gaaacaaggc tttacaacca
     2701 agcaaacaga cttagactta aaaagattta cagcttgcgt tggggttttc cttttcattg
     2761 ataataaact gtcctcaagc tc
//
