LOCUS       NM_001417808            1592 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus lamin tail domain containing 1 (Lmntd1), transcript
            variant 2, mRNA.
ACCESSION   NM_001417808
VERSION     NM_001417808.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Galbiati,F., Pettinicchio,A., Dragani,T.A. and Manenti,G.
  TITLE     Allelic effects of mouse Pas1 candidate genes in human lung cancer
            cell lines
  JOURNAL   Cancer Lett 244 (2), 176-181 (2006)
   PUBMED   16458428
REFERENCE   2  (bases 1 to 1592)
  AUTHORS   Liu,P., Wang,Y., Vikis,H., Maciag,A., Wang,D., Lu,Y., Liu,Y. and
            You,M.
  TITLE     Candidate lung tumor susceptibility genes identified through
            whole-genome association analyses in inbred mice
  JOURNAL   Nat Genet 38 (8), 888-895 (2006)
   PUBMED   16862160
REFERENCE   3  (bases 1 to 1592)
  AUTHORS   Wang,M., Futamura,M., Wang,Y. and You,M.
  TITLE     Pas1c1 is a candidate for the mouse pulmonary adenoma
            susceptibility 1 locus
  JOURNAL   Oncogene 24 (11), 1958-1963 (2005)
   PUBMED   15688036
  REMARK    GeneRIF: Pas1c1(lmna-rs1) is a candidate for the Pas1 locus and the
            strain-specific isoforms may have differential effects on cell
            proliferation in lung adenoma.
REFERENCE   4  (bases 1 to 1592)
  AUTHORS   Manenti,G., Galbiati,F., Gianni-Barrera,R., Pettinicchio,A.,
            Acevedo,A. and Dragani,T.A.
  TITLE     Haplotype sharing suggests that a genomic segment containing six
            genes accounts for the pulmonary adenoma susceptibility 1 (Pas1)
            locus activity in mice
  JOURNAL   Oncogene 23 (25), 4495-4504 (2004)
   PUBMED   15064703
  REMARK    GeneRIF: Lmna-rs1 is part of the complex multigenic Pas1 locus. It
            may be a tumor suppressor. AA changes and downregulation are
            associated with lung adenoma susceptibility.
REFERENCE   5  (bases 1 to 1592)
  AUTHORS   Wang,M., Lemon,W.J., Liu,G., Wang,Y., Iraqi,F.A., Malkinson,A.M.
            and You,M.
  TITLE     Fine mapping and identification of candidate pulmonary adenoma
            susceptibility 1 genes using advanced intercross lines
  JOURNAL   Cancer Res 63 (12), 3317-3324 (2003)
   PUBMED   12810665
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153577.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053420.1, SRR5189685.145059.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849379 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               AC153577.2         129426-129637       c
            213-322             AC153577.2         129238-129347       c
            323-573             AC153577.2         125432-125682       c
            574-769             AC153577.2         122831-123026       c
            770-956             AC153577.2         115240-115426       c
            957-1076            AC153577.2         112952-113071       c
            1077-1282           AC153577.2         108935-109140       c
            1283-1455           AC153577.2         100005-100177       c
            1456-1592           AC153577.2         92792-92928         c
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 77.37 cM"
     gene            1..1592
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /note="lamin tail domain containing 1"
                     /db_xref="GeneID:74071"
                     /db_xref="MGI:MGI:1921321"
     exon            1..212
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            213..322
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            323..573
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            574..769
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            770..956
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1076
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1282
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1455
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1592
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1567..1572
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /note="hexamer: AATAAA"
     polyA_site      1592
                     /gene="Lmntd1"
                     /gene_synonym="4933403M22Rik; Ifltd1; Lmna-rs1; Lmna1"
                     /note="major polyA site"
ORIGIN      
        1 agaggcagtg gtggccagat gcgaggtcgt tggttgtcat aaaggctgag ctgctcgcca
       61 tggtctctct gtggtttgtc tcagattctt cgcccataga gagaggcatt gaatacgtcg
      121 actctgacat ttctcgtgag aatggtcttt ctagtaccag tgtagcaaag gaatcataaa
      181 atttgataaa ctgaagacag ttggattagc agggaagaga agaggcacct cctctgccag
      241 ccatgatgaa ggaagcatcg gagcctctag ccagtgtcac cagcatcaat aagcaagaca
      301 gtaaagtaca ggatggagag ataagaaaag aaaaaattgg aaccatcact ccatcgaaac
      361 agcattcttc agtccacttc ttcccaaaga taatggattc agactccacc acgctcatcc
      421 cgttgtcccg ctcattttcc caagaaatgc caattggctt ctaccagatc accagcaccc
      481 agaacagctc caccttatcg tccagaggac agctggcttc taaatccacc atcctgagct
      541 gctcccacaa agacagcagc ctgggaaagc agagcaccag ctccatggtt ccacggaggc
      601 agccccagtc gagctctgac gtggatacgt atacttttgg gaatggtgag gattatttcc
      661 tttctttgtt tggagaatcg aagaagctca ccgcccacac accccaagcc gagaacgtga
      721 gcgaacacct ttctgtgatc cttgaggaag tcggccaatt tacatccagt tctctcggag
      781 aaattaaaat agctgaggta aatatcaagg gcctctttgt gaggcttgtc aactcctcca
      841 atgaaaagga agtagagatt ggaaaccaca ttcttcagca aaacgtgaat ggacacgcag
      901 tctccttgta ccagttcccc gacaacatca cactgcaggc caactccacg gtgacagtgt
      961 gggcagcagc ttcggaagca aagccacagc caccaacgga ctttgtttgg gaggaacaga
     1021 gcaagttccg atccagtccg gactgcacga ccatcttgtg caagcccaat ggtgaggcca
     1081 ttgcctggta cactcctatc cactggaagc aagcctggga gaagttagag actgacattg
     1141 aattcgaaag atgctcagtg gtggtcccat caatgagaaa ccacatgttt ggatggataa
     1201 cagcatctgt ctcttccaca aacgaggaga aagaagaacc aatacagaaa acgccctccc
     1261 aagtctaccc tgtcctctac agagaaaagg aaatcccgcc aactgtctta cccaataaga
     1321 gcccctggtg ccgcaatccc aacacttctc cacatccgta cagctctctg attgactcac
     1381 atgactcgga catttccgaa agcagtttag atacacagct caagcctcag ccaaccaagc
     1441 ccaaaccaga cccagggacc aagaaaaaga aagcaaagtc ataagaaaat ggaaagccat
     1501 gaaatctgtg aacgtgagta actattgtag agttgcttta taacaaaata ttccacaaat
     1561 aattgcaata aatttttgag ggtctcgctt ta
//
