LOCUS       NM_178919               2861 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus lipase maturation factor 2 (Lmf2), transcript variant
            1, mRNA.
ACCESSION   NM_178919
VERSION     NM_178919.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2861)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113976.13.
            
            On Jan 20, 2023 this sequence version replaced NM_178919.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079532.1, AK149934.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-255               AC113976.13        133140-133394       c
            256-509             AC113976.13        132348-132601       c
            510-538             AC113976.13        132211-132239       c
            539-753             AC113976.13        131867-132081       c
            754-932             AC113976.13        131613-131791       c
            933-1074            AC113976.13        131241-131382       c
            1075-1209           AC113976.13        130994-131128       c
            1210-1315           AC113976.13        130818-130923       c
            1316-1412           AC113976.13        130643-130739       c
            1413-1595           AC113976.13        130388-130570       c
            1596-1764           AC113976.13        130143-130311       c
            1765-1876           AC113976.13        129937-130048       c
            1877-1973           AC113976.13        129767-129863       c
            1974-2861           AC113976.13        128784-129671       c
FEATURES             Location/Qualifiers
     source          1..2861
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 44.84 cM"
     gene            1..2861
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /note="lipase maturation factor 2"
                     /db_xref="GeneID:105847"
                     /db_xref="MGI:MGI:2146015"
     exon            1..255
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..2270
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transmembrane protein 153; transmembrane protein 112B"
                     /codon_start=1
                     /product="lipase maturation factor 2 isoform 1"
                     /protein_id="NP_849250.1"
                     /db_xref="CCDS:CCDS27746.1"
                     /db_xref="GeneID:105847"
                     /db_xref="MGI:MGI:2146015"
                     /translation="MASSRVPQQLFLQGVAAVYLFAFASLYTQIPGLYGPEGILPARR
                     TLRPQGKGLWQQLWETPTLLWEAPRLGLDTAQGLDLLTLLGTVLALGALLLNSLRHPF
                     VYLLLWVAYRSAYQVGQVFLYFQWDSLLLETGFLAILVAPLRGPSKHKILQGRLAGAL
                     PHEDLPFWLVRWLLFRLMFASGVVKLTSRCPTWWGLTALTYHYETQCLPTPAAWFAHH
                     LPVWLHKLSVVATFLIEIAVPPLFFAPIRRLRLTAFYAQALLQVLIIITGNYNFFNLL
                     TLVLTTALLDDRHLSAEPGLRCHKKMPTSWPKALLTALSLLLELTVYGLLAYGTVYYF
                     GLEVDWQQHIILSKTTFTFHQFSQWLKTVTLPTVWLGTASLAWELLVVLWRWIQVQGW
                     SRKFSAGIQLSVLGTATVALFLISLVPYSYVEPGTHGRLWTGAHRLFGSVEHLQLANS
                     YGLFRRMTGVGGRPEVVLEGSYDGQHWTEIEFMYKPGNVSRPPPFLTPHQPRLDWQMW
                     FAALGPHTHSPWFTGLVLRLLQGKEPVIRLVQSHVANYPFHERPPTYLRAQRYKYWFS
                     KPGDQSRWWHRQWVEEFFPSVSLGDPTLETLLQQFGLKDKSPPRARSPSNGLAQTLNW
                     VRTQLSPLEPPILLWGLFGAVVAIRVVQTLLAPRPLQSSKQTREEKRKQTSKKDSRAA
                     SEQAAANSNSRDSWAPRRKK"
     exon            256..509
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            510..538
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            539..753
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            754..932
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1074
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1209
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1315
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1412
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1595
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1764
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1876
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1973
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2861
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2697..2702
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /note="hexamer: AATAAA"
     polyA_site      2722
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /note="major polyA site"
     regulatory      2838..2843
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
                     /note="hexamer: AACAAA"
     polyA_site      2861
                     /gene="Lmf2"
                     /gene_synonym="Tmem112b; Tmem153"
ORIGIN      
        1 agactaagtt tctaggtggt tagcggtgag ttctttggca ctgggtggag ctcagtgacc
       61 cgaccggact gacggattcc ggctgcggcg tgggccagag gccgggctgg gggcagctag
      121 gagactagag ggcactactt cggcaagacc gcgtagcgga catggcgagc tcccgggtcc
      181 cacagcagct tttcctacag ggtgtggccg ctgtctactt gttcgccttt gcgtccctct
      241 acacccagat cccaggcctc tatggcccag agggcatcct tcctgctcga agaacactgc
      301 ggccccaagg caagggcctg tggcagcagc tgtgggaaac accaacgctg ctgtgggagg
      361 caccaagact ggggctggat actgcccaag gtctggattt actgacctta ttgggcaccg
      421 tgctagccct gggcgccctg ctcctgaact ctctgagaca ccccttcgtc tacctgctgc
      481 tctgggttgc ataccgatca gcctaccagg tgggccaagt gttcctttat ttccagtggg
      541 attccctgct gctggagact ggcttcctag ctatactggt agccccgctg agggggcctt
      601 ccaaacacaa gattctccag ggtagattag caggagcctt accccatgaa gacctcccat
      661 tctggctcgt gcgctggctg ctgtttcgac tcatgttcgc ctctggtgtg gtcaagttga
      721 ccagccgctg ccctacgtgg tggggactca ctgctctgac ctaccactat gagactcagt
      781 gcctgcccac acccgctgcc tggtttgctc accatctgcc ggtctggcta cacaagctca
      841 gcgtggtagc caccttcctc atcgagatcg cagtgccacc cctgttcttt gctcctattc
      901 gccgcctacg acttactgcc ttctacgctc aggcattatt gcaagtcctg attatcatca
      961 ctggcaacta caatttcttc aacctgctaa ccctggtgct caccactgcc ctcctggatg
     1021 accgtcacct gtctgctgag cctggcctca gatgccacaa gaagatgccc acctcctggc
     1081 ctaaagccct gctgaccgcg ctgtccttac tgctggaact gactgtctat gggctgctgg
     1141 cctacggcac tgtctactac tttggcctgg aggttgactg gcaacagcac atcatcctct
     1201 cgaaaaccac cttcaccttc catcagttct cccagtggct gaagacggta accctgccaa
     1261 ctgtgtggct agggacagcc tccctggcct gggagttgct tgttgtcctc tggaggtgga
     1321 tccaggtaca aggatggtca cggaagttct ctgcgggtat ccagctctcc gtcctgggca
     1381 cggcaacagt ggccttgttc ctgatcagcc tagtacctta ctcctatgtg gaacctggga
     1441 cccacgggcg tctctggact ggggctcatc gcctgttcgg ttctgtggag cacctacagc
     1501 tggccaactc ttacggcctt ttccgtcgga tgactggcgt gggcgggcgg ccggaagtgg
     1561 tcctagaggg cagctatgac ggacagcatt ggacagagat cgaattcatg tacaaacctg
     1621 ggaatgtgag ccgaccaccc cctttcctga ctcctcacca gccacgcctt gattggcaga
     1681 tgtggttcgc agcccttggc ccgcatacac acagcccctg gttcaccggc ctggtgctgc
     1741 gcctcctgca gggcaaggag ccagtgatcc gactagtcca gagccatgtt gccaactacc
     1801 cctttcatga acggccaccc acctacctgc gggcccagcg ctataagtac tggttctcaa
     1861 agcctggaga tcagagccgg tggtggcacc gccagtgggt agaggaattc ttcccatctg
     1921 tatccttggg ggacccaaca ctggaaaccc tgctccaaca gtttggacta aaggataaga
     1981 gtccaccccg ggcccgcagc cccagcaatg gcctagctca gacactgaac tgggtgcgga
     2041 cacagctgtc tcccctggag cctcccatcc tgctctgggg gctcttcggg gcagtggtgg
     2101 ctatccgagt tgtgcagacc ctactcgccc cccgcccgct ccagtcctca aaacagacta
     2161 gagaggaaaa acgtaagcaa acctccaaga aggattccag agccgcctct gagcaggctg
     2221 ccgccaacag caacagcagg gactcctggg cccctcggcg gaaaaaatag cgtcgtgtgc
     2281 taccatcagc tggccacgtg tcctaatgat gaagtcagag ccccgggatc ccagcacaca
     2341 ccgtgacaca gcccagccac tgtgccttag ccagtcctgc cagggcagat gcagacggga
     2401 acgccacccc cgaggaatgc tgggtgtcac ctttgagagc cctgctcatc cccctacacc
     2461 aaccacatcc ttcgctactc accttctact gtcttggaat caacccagaa gtgggcctgc
     2521 ggcctagctc aggacttctc ctgaaacact gtaatcagtg taccatagat gcacaggcct
     2581 gagtctggag ttcctaccca gccccacttt ggagaggggg agctaaacct gctgaggaca
     2641 ggagccaggg gaagtgggtc cttgagactg tgcctgcctg cccctcagac tgtaccaata
     2701 aaggcccatt tgtacatacc catttactag tggtttttcc ttctgaggag gcctgaggat
     2761 agctggcaca gcctagactg gttactgact gggctaaatg ggctccctcc ttgtagctca
     2821 atgttctcca taaaataaac aaaaaggcct ggttatgaga a
//
